Santa Cruz
Seville
Visit Santa Cruz
Popular places to visit
Royal Alcázar of Seville
Discover a millennium’s worth of royal treasures in this architectural masterpiece in the heart of Seville.
Giralda Tower
Once among the tallest religious monuments in the world, this former minaret is now the eye-catching bell tower to Seville Cathedral.
Triunfo Plaza
From this ancient and picturesque square, access some of the oldest and most impressive buildings in Seville, including the world’s largest gothic cathedral.
Cabildo Catedral
Stop by a 16th-century meeting room inside the Cathedral of Seville that is stunningly decorated with religious paintings, sculptures and reliefs.
San Telmo Palace
Tour the striking interior and exterior of a palatial building that serves as the headquarters of the president of the autonomous region of Andalusia.
University of Seville
Enjoy the collegiate vibe when you visit University of Seville, during your travels in Paseo de Las Delicias. Visit the stunning cathedral and shops in this culturally rich area.
Things to do
Cathedral & Alcázar of Seville Guided Tour Combo
Boat Trip "Los Rincones del Guadalquivir"
Ticket for Casa de la Guitarra Flamenco Show
Three Cities in One Day: Córdoba, White Villages and Ronda from Sevilla
Flamenco Show at Tablao El Arenal with Drink and Optional Dinner or Tapas
Flamenco Show at Casa de la Memoria Admission Ticket
Santa Cruz Hotel Deals
Hotel Murillo
I do not recommend staying here. Our room was extremely loud. There is a restaurant right outside the hotel that’s open till 1am and all of the noise from people eating outside comes up into the room. Then when the restaurant finally closes at 1am, you get the noise of them cleaning up the restaurant ...
Reviewed on May 15, 2026
Las Casas de la Judería, Sevilla Historic City Center
Good breakfast.
Reviewed on May 15, 2026
Hotel Amadeus Sevilla
Nice location and music every way …
Reviewed on May 16, 2026
Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
The property was beautiful and very well maintained and the hotel is centrally located which is the biggest plus. The front desk was also extremely helpful and the breakfast was great as well. The concierge were not as helpful as I thought but nothing to complain but rest of the staff up to the room ...
Reviewed on May 16, 2026
Hotel Rey Alfonso X
Perfect well localed too
Reviewed on May 16, 2026
Hotel Murillo Reinoso
The place was sensational Central to everything that you need to do in Seville. From check in with Laura to check out cannot fault anyone or anything.
Reviewed on May 12, 2026
Other neighborhoods around Santa Cruz
El Arenal
Located in Seville's historical center, El Arenal boasts the 13th-century Torre del Oro, Royal Shipyards, and La Real Maestranza bullring. Explore this vibrant area on the Guadalquivir river's east bank.
San Bartolomé
Travelers come to San Bartolomé for its lively bars, and you can see top attractions like Pilate's House and Zurbarán Statue while you're in town.
Alfalfa
Unique features of Alfalfa include the bars and historic sites. Make a stop by Salvador Plaza or Calle Sierpes while you're exploring the area.
Historical Center
Casa de la Memoria Cultural Center and Calle Sierpes are a few top attractions in Historical Center. Hop around the city on the metro at Plaza Nueva Tram Stop or Archivo de Indias Tram Stop and check out the area's fantastic nightlife, stunning cathedral, and popular shops.
La Florida
The restaurants and shopping are a few reasons travelers visit La Florida. Want to see more of the surrounding area? Murillo Gardens and Pilate's House are a few top sights nearby.
San Bernardo
Even though there aren't top sights in San Bernardo, you can explore the larger area and take in top sights like Murillo Gardens. Jump on the metro at Prado San Sebastián Tram Stop to see more of the city.
