Otay Mesa, CA
San Diego
Visit Otay Mesa
Stay near popular Otay Mesa attractions
Things to do
From Tijuana: Valle de Guadalupe Shared Winery Tour
￥13,202
per adult
100% of travellers recommend
From Tijuana: Valle de Guadalupe Private Winery Tour
￥22,762
per adult
100% of travellers recommend
Taco Tuesday Hop to Tijuana from San Diego
￥13,021
per adult
Tour of San Diego>Rosarito >Giant Christ>Puerto Nuevo Lobster
￥23,532
per adult
Otay Mesa Hotel Deals
Wyndham San Diego Bayside
1355 N Harbor Drive San Diego CA
The price is ￥24,091 per night from Oct 26 to Oct 27
￥24,091
￥33,443 total
Oct 26 - Oct 27
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,329 reviews)
"1. Housekeeping did not show up to service the room until 6:30 pm 2. Adjacent restaurant (claim jumpers) had extremely poor service"
Reviewed on Oct 14, 2026
Paradise Point Resort & Spa
1404 Vacation Rd San Diego CA
Fully refundableReserve now, pay when you stay
The price is ￥32,670 per night from Nov 8 to Nov 9
￥32,670
￥45,948 total
Nov 8 - Nov 9
includes taxes & fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8.8/10 Excellent! (2,939 reviews)
"The property is very beautiful; however, it feels a tad bit outdated. Overall, we enjoyed our stay and wouldn’t mind staying again."
Reviewed on Oct 14, 2026
Handlery Hotel
950 Hotel Cir N San Diego CA
The price is ￥14,673 per night from Nov 12 to Nov 13
￥14,673
￥16,866 total
Nov 12 - Nov 13
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff ...
Bay Club Hotel & Marina
2131 Shelter Island Dr San Diego CA
The price is ￥24,083 per night from Oct 28 to Oct 29
￥24,083
￥27,683 total
Oct 28 - Oct 29
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant in ...
Sheraton San Diego Resort
1380 Harbor Island Dr San Diego CA
The price is ￥22,009 per night from Nov 1 to Nov 2
￥22,009
￥33,307 total
Nov 1 - Nov 2
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
8.6/10 Excellent! (3,763 reviews)
"Beautiful property, however cleaning staff could have been more helpful. Also, nobody answered the guest service phone."
Reviewed on Oct 14, 2026
Hard Rock Hotel San Diego
207 5th Ave San Diego CA
The price is ￥26,074 per night from Nov 3 to Nov 4
￥26,074
￥37,893 total
Nov 3 - Nov 4
includes taxes & fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Otay Mesa
Find the best Otay Mesa areas and neighborhoods for the activities you enjoy most. Learn more about Otay Mesa
Learn more about Otay Mesa
Downtown San Diego
Petco Park and Port of San Diego are a few top attractions in Downtown San Diego. Hop around the city on the metro at Civic Center Station or Civic Center Station and check out the area's fantastic nightlife, fascinating museums, and beautiful waterfront views.
Pacific Beach
The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Pacific Beach while you're exploring the area.
Gaslamp Quarter
Fantastic nightlife and popular shops are a few of the things travelers enjoy most about Gaslamp Quarter. A visit to Gaslamp Museum at the Davis-Horton House or Nova SD is also recommended, and you can jump aboard the metro at Gaslamp Quarter Station to get around town.
Mission Beach
If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.
Mission Bay
If you're spending some time in Mission Bay, Mission Bay and Ski Beach are top sights worth seeing.
Otay Mesa, CA
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