The Best Hotels Closest to Penn Center in Saint Helena Island for 2026

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Our top choices for Penn Center hotels

1. City Loft Hotel

9.9 km from Penn Center

Terri

￥28,045 total

includes taxes & fees

Aug 4 - Aug 5

2. Best Western Sea Island Inn

10.2 km from Penn Center

Matt

￥31,584 total

includes taxes & fees

Aug 16 - Aug 17

3. Beaufort Inn

10 km from Penn Center

"Wish we had more time to spend in the Beaufort area. A very lovely Inn & charming town to visit. The staff is very welcoming . Our room was perfect for an overnight....would like one of the larger rooms if we were to stay longer. Breakfast in the morning was delicious.... Fresh, warm Southern biscuits as well as donuts were a hit With a location of the Inn in the historic district, it makes strolling around the town and the waterfront very easy. Look forward to our next visit!"

Mary Sue

￥29,565 total

includes taxes & fees

Aug 10 - Aug 11

4. 607 Bay Inn Downtown Beaufort

9.8 km from Penn Center

Marni

￥32,855 total

includes taxes & fees

Aug 3 - Aug 4

5. Rhett House Inn

10.3 km from Penn Center

CHRISTINE

￥37,918 total

includes taxes & fees

Jul 23 - Jul 24

6. Tru by Hilton Beaufort, SC

14.9 km from Penn Center

Scott

￥19,655 total

includes taxes & fees

Aug 2 - Aug 3

7. Holiday Inn Hotel & Suites Beaufort at Highway 21 by IHG

12.7 km from Penn Center

Courtney

￥19,103 total

includes taxes & fees

Aug 22 - Aug 23

8. Hampton Inn Beaufort

13 km from Penn Center

Alicca

￥22,958 total

includes taxes & fees

Aug 22 - Aug 23

9. Anchorage 1770

10.3 km from Penn Center

Jeanne

￥46,713 total

includes taxes & fees

Jul 29 - Jul 30

10. Hilton Garden Inn Beaufort

12 km from Penn Center

James

￥23,175 total

includes taxes & fees

Aug 5 - Aug 6

11. Home2 Suites BY Hilton Beaufort, SC

15 km from Penn Center

Maria

￥24,895 total

includes taxes & fees

Aug 21 - Aug 22

12. Cuthbert House

10.4 km from Penn Center

Ivan

￥64,940 total

includes taxes & fees

Aug 10 - Aug 11

13. Sleep Inn Beaufort near MCAS

13.7 km from Penn Center

Eugene

￥15,043 total

includes taxes & fees

Aug 16 - Aug 17

14. Comfort Suites near MCAS Beaufort

13.8 km from Penn Center

Heriberto

￥19,478 total

includes taxes & fees

Aug 5 - Aug 6

Room, 1 King Bed, Refrigerator & Microwave | Desk, iron/ironing board, WiFi (free), bed sheets

15. Oasis Inn

12.8 km from Penn Center

Steven

￥16,087 total

includes taxes & fees

Jul 26 - Jul 27

16. Oceanfront St Helena Island Condo w/ Beach Access!

13.7 km from Penn Center

Darrell

￥84,138 total

includes taxes & fees

Aug 5 - Aug 6

17. Super 8 by Wyndham Port Royal/Beaufort

10.3 km from Penn Center

John David Moore

￥12,764 total

includes taxes & fees

Aug 16 - Aug 17

18. Howard Johnson by Wyndham Beaufort/Parris Island

15.1 km from Penn Center

Pamela

￥12,763 total

includes taxes & fees

Aug 16 - Aug 17

19. America's Best Inn and Suites Beaufort

13.4 km from Penn Center

Shauna

￥14,299 total

includes taxes & fees

Jul 26 - Jul 27

20. Harbor Island Beach Retreat - Steps to Ocean!

13.8 km from Penn Center

￥69,894 total

includes taxes & fees

Aug 5 - Aug 6

View all properties

Compare popular hotels close to Penn Center

Property	Star rating	Guest rating
City Loft Hotel	3.5 star property	9.6 Exceptional 845 reviews	View
Best Western Sea Island Inn	2.5 star property	9.6 Exceptional 1,001 reviews	View
Beaufort Inn	3.5 star property	9.0 Wonderful 1,000 reviews	View
607 Bay Inn Downtown Beaufort	2.5 star property	9.8 Exceptional 122 reviews	View
Rhett House Inn	4.0 star property	9.2 Wonderful 680 reviews	View

Top Penn Center Hotel Reviews

Best Western Sea Island Inn

10/10 Excellent

"This place just feels super good. The rooms are kinda basic but nice- nothing unusual but the people who work here are really kind and the place just feels very warm and home like. The location is the best- right next to beautiful views. The breakfast is really good- the scones especially are fire."

Sweet cottage, Best Location, Close to Everything, River View

10/10 Excellent

"Would highly recommend staying here if you are visiting Beaufort! Great location to downtown Beaufort and surrounding islands. The house was spotless and identical to what you see in the pictures. Barbara did an excellent job communicating leading up to our stay and helped us have a stress free trip!"

Relax in a Pet-Friendly Lowcountry Home Near Beaches, Downtown Beaufort, and USMC Graduation!

10/10 Excellent

"We are so happy we found this house for our vacation. We have older teens-adult kids, 5 between the ages of 13-19. Which means, the 3 bathrooms were a HUGE plus for us. The neighborhood was great! Quiet, relaxing, after the 1st night, we didn’t even lock the motorcycle. Plenty of room for everyone, clean, all the basics you need in the kitchen. It’s also really close to get to everything you could want to do while you’re there. Would highly recommend!"

Charming Custom Carriage House on 40 Acres! Only 5 minutes to Beaufort's Bay St.

10/10 Excellent

"We have stayed at this carriage house many times. It’s perfect for a couples getaway. It is furnished to meet our every need and the property is impeccable. We will be back again."

Ranch, 6 bedrooms and 5 baths home near Parris Island and Beaufort is beautiful.

8/10 Good

"The home is great for a large family and comfortable. There were 10 us at the house. Travelers do not have control over the thermostat and must text the owners if you want it adjusted. The heat and humidity were significant while we were there which is why central AC was important to us and we had to keep asking the owners to turn it down and keep it at 68 as we weren't comfortable at night. Once that was done, all was well in that area. We two of the shower faucet handles were not attached and came off easily. We were able to make it work and saw that a replacement kit was on the kitchen counter and just hadn't been installed in one of them. We discovered mouse droppings in the cabinet under the kitchen sink where mice had enjoyed snacking on the spare sponges. We ran out of toilet paper quickly and there was only one backup roll. Additionally, there were only two bath towels per room (12 towels) which wasn't enough for 10 people, most of whom were women. There was also no dishwasher detergent so we bought our own. The owners did also drop some off. Overall, the house is great and comfortable. We were there for my son's graduation from Parris Island boot camp so it was a great place for our large family to stay during this time. A couple of tweaks to make sure there are enough supplies and some minor maintenance were all that was needed. Would stay there again!"

Dreamworthy, waterfront St. Helena home with pool and deep water dock.

8/10 Good

"Eric was very responsive and quickly resolved our check in code issue, the home was maintained well and clean, the pool was clean (although due to nature - not the homeowner- it needed daily cleaning) and was a huge hit with our kids, the dock had lovely views and was great for fishing and crabbing. We spent the vast majority of our time outside at the outdoor seating area, the pool, and the dock. Another plus, was having the guesthouse (although we didn't cook or sleep in it) to have the fridge to keep our drinks cold and closer to where we spent our time. We had a wonderful stay and look forward to returning in the future."

The Offbeat Oasis by the Marsh- State Park Pass Included🏖

10/10 Excellent

"We loved our stay on the marsh at St Helena!! We enjoyed the morning sunrise over the marsh as we enjoyed our coffee. We took full advantage of the kitchen. The home was very clean and we slept comfortably. We hope to visit again soon!!"

Hotels near other Penn Center attractions

Sanctuary Golf Club

Enjoy a round of golf in Beaufort at Sanctuary Golf Club. Wander the beautiful beaches in this family-friendly area.

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Frequently asked questions

What's the area like around Penn Center?

Penn Center is located in a historic area of Saint Helena Island known for its beautiful island views. You'll find 66 hotels and other accommodations within a few miles for a convenient home base.

What's the best hotel to stay close to Penn Center?

"The Mini Hideaway"-Short drive to Hunting Island State Park(PASS INCLUDED) is one of the top choices for your stay based on our traveler data, and this guesthouse offers private decks and free WiFi. It's located 2.2 mi (3.6 km) from Penn Center.

How many hotels should I expect to find close to Penn Center?

Expedia has 66 hotels and other accommodations a few miles from Penn Center.

If I need to cancel the hotel reservation for my stay near Penn Center, will I receive a refund?

Yes, most hotel reservations are refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, it may still be possible to cancel it and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the top deals on offer near Penn Center.

Where can I learn more about changing or cancelling my trip in the area near Penn Center?

To find more details about updating your stay near Penn Center or cancelling it, go to https://www.expedia.com/service/.

What can I see and do near Penn Center?

Attractions like York W. Bailey Museum and Red Piano Too Gallery highlight the local culture. You can enjoy nature at Horse Island, Cherry Hill Knoll Island, or Sheep Island. You might plan a visit to Cat Island Driving Range or Sanctuary Golf Club while you're in the area.

Find hotels near Penn Center, Saint Helena Island from ￥12,763

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Our top choices for Penn Center hotels

1. City Loft Hotel

2. Best Western Sea Island Inn

3. Beaufort Inn

4. 607 Bay Inn Downtown Beaufort

5. Rhett House Inn

6. Tru by Hilton Beaufort, SC

7. Holiday Inn Hotel & Suites Beaufort at Highway 21 by IHG

8. Hampton Inn Beaufort

9. Anchorage 1770

10. Hilton Garden Inn Beaufort

11. Home2 Suites BY Hilton Beaufort, SC

12. Cuthbert House

13. Sleep Inn Beaufort near MCAS

14. Comfort Suites near MCAS Beaufort

15. Oasis Inn

16. Oceanfront St Helena Island Condo w/ Beach Access!

17. Super 8 by Wyndham Port Royal/Beaufort

18. Howard Johnson by Wyndham Beaufort/Parris Island

19. America's Best Inn and Suites Beaufort

20. Harbor Island Beach Retreat - Steps to Ocean!

Compare popular hotels close to Penn Center

Top Penn Center Hotel Reviews

Best Western Sea Island Inn

Hotels near other Penn Center attractions

Sanctuary Golf Club

Frequently asked questions