Find hotels in Otay Mesa, San Diego from ￥9,805

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Discover 4,517 Otay Mesa hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Terrace/patio
Hampton Inn & Suites Imperial Beach San Diego
2.5 star property
9.4 out of 10, Exceptional, (635)
"Great place to stay everything was clean and needs are cozzy. Pier not so far and lots of restaurants near by"
The price is ￥22,442
per night
May 27 - May 28
Hampton Inn & Suites Imperial Beach San Diego
Lobby lounge
Fairfield Inn & Suites by Marriott Tijuana
3.5 star property
9.2 out of 10, Wonderful, (1000)
"Nice "
The price is ￥16,287
per night
May 26 - May 27
Fairfield Inn & Suites by Marriott Tijuana
Property entrance
Hotel Ticuán
3.5 star property
9.0 out of 10, Wonderful, (1716)
"The people are amazing "
The price is ￥13,915
per night
May 16 - May 17
Hotel Ticuán
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Terrace/patio
Quartz Hotel & SPA
4.5 star property
9.0 out of 10, Wonderful, (1007)
"The staff was super friendly! We loved the spa and the couple's massage. It was very relaxing. The food was delicious, and our server was excellent. We will be staying here again."
The price is ￥25,388
per night
Jun 2 - Jun 3
Quartz Hotel & SPA
Premium bedding, pillowtop beds, in-room safe, individually decorated
Hotel Real del Río
3.5 star property
9.0 out of 10, Wonderful, (1000)
"I’ll recomend this place , very relaxing"
The price is ￥18,982
per night
May 28 - May 29
Hotel Real del Río
Outdoor pool
Grand Hotel Tijuana
3.5 star property
8.8 out of 10, Excellent, (2466)
"The staff is really nice. And they had nice views of the city and the golf course. Is very convenient to everything also"
The price is ￥18,861
per night
Jun 2 - Jun 3
Grand Hotel Tijuana
Exterior
Loews Coronado Bay Resort
4.0 star property
8.6 out of 10, Excellent, (1054)
"A quiet and peaceful place to relax"
The price is ￥34,214
per night
May 27 - May 28
Loews Coronado Bay Resort
Reception
Hotel Caesar's
2.5 star property
8.6 out of 10, Excellent, (1000)
"Best"
The price is ￥10,311
per night
May 19 - May 20
Hotel Caesar's
Beach/ocean view
Hotel Jatay
3.0 star property
8.6 out of 10, Excellent, (1000)
"Location"
The price is ￥11,855
per night
Jun 10 - Jun 11
Hotel Jatay
Terrace/patio
Hotel Grand One Plaza
3.0 star property
8.4 out of 10, Very Good, (598)
"A little noise, but staff very friendly and accommodating "
The price is ￥8,125
per night
May 15 - May 16
Hotel Grand One Plaza
Terrace/patio
Holiday Inn Tijuana Zona Rio, an IHG Hotel
3.5 star property
8.4 out of 10, Very Good, (1337)
"Everything is ok "
The price is ￥15,731
per night
Jun 9 - Jun 10
Holiday Inn Tijuana Zona Rio, an IHG Hotel
Front of property
Sand Castle Inn
2.5 star property
8.4 out of 10, Very Good, (421)
"Nice little hotel located across the street from the beach. Parking is a little cramped "
Sand Castle Inn
Outdoor pool
Marriott Hotel Tijuana
4.5 star property
8.4 out of 10, Very Good, (1003)
"Great service but elevators were stuck and hot water was difficult to get/regulate. "
The price is ￥19,544
per night
May 26 - May 27
Marriott Hotel Tijuana
Lobby lounge
City Express Plus by Marriott Tijuana
3.0 star property
8.4 out of 10, Very Good, (1008)
"This was an awesome experience "
The price is ￥17,200
per night
May 19 - May 20
City Express Plus by Marriott Tijuana
Meeting facility
Pier South Resort, Autograph Collection by Marriott
4.0 star property
8.4 out of 10, Very Good, (1000)
" Beautiful room and ocean view and great hospitality staff! I just finding like the flies outside of my room and a few inside my room :( "
The price is ￥32,652
per night
May 16 - May 17
Pier South Resort, Autograph Collection by Marriott
Outdoor pool
Hotel Lucerna Tijuana
4.5 star property
8.2 out of 10, Very Good, (1002)
"View was amazing"
The price is ￥25,103
per night
Jun 2 - Jun 3
Hotel Lucerna Tijuana
Standard Double Room | Desk, laptop workspace, blackout drapes, iron/ironing board
Baja Inn Hoteles Rio
3.5 star property
8.2 out of 10, Very Good, (1000)
"The staff great customer service, attention to detail Thanks for everything Mr. Fernando."
The price is ￥15,431
per night
May 15 - May 16
Baja Inn Hoteles Rio
Lobby lounge
City Express by Marriott Tijuana Río
3.0 star property
8.2 out of 10, Very Good, (1000)
"Nice to have Security in the lobby and be a deterrent but Security needs to be friendly with guests during the stay."
The price is ￥17,191
per night
Jun 2 - Jun 3
City Express by Marriott Tijuana Río
3 outdoor pools
Rosarito Beach Hotel
3.0 star property
7.8 out of 10, Good, (1001)
"I like services"
The price is ￥15,803
per night
May 15 - May 16
Rosarito Beach Hotel
Lobby
Del Mar Inn Rosarito
3.0 star property
7.8 out of 10, Good, (894)
"Quiet, Clean, and in-house bar. Drinks are the bomb. "
The price is ￥13,147
per night
May 28 - May 29
Del Mar Inn Rosarito
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Otay Mesa

Hotels in top San Diego neighborhoods Learn more about Otay Mesa
US Grant Hotel

Downtown San Diego

2 out of top 10 points of interest in this area
4.5/5(8,497 area reviews)

Petco Park and USS Midway Museum are a few top attractions in Downtown San Diego. Hop around the city on the metro at Civic Center Station or Civic Center Station and check out the area's fantastic nightlife, fascinating museums, and beautiful waterfront views.

Find hotels in Downtown San Diego

Otay Mesa hotels information

Number of reviews
21,697
Accommodation
4,517 hotels
Lowest Price
￥9,805
Highest Price
￥34,214

Frequently asked questions

What's it like in Otay Mesa?

Otay Mesa is a neighborhood that travelers like for its beaches, restaurants, and shopping.

Where is the best hotel for a stay in Otay Mesa?

Based on Expedia customer reviews, Quality Suites San Diego Otay Mesa is the highest ranked property in Otay Mesa. This hotel offers free breakfast and an outdoor pool. Another top choice in the area is Holiday Inn Express Hotel & Suites San Diego Otay Mesa, an IHG Hotel.

How many hotels will I be able to find in the Otay Mesa area?

Expedia has 5 Otay Mesa hotels and other accommodations, and one might make a good home base for venturing out into the greater San Diego area.

If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Otay Mesa.

Where can I learn more about changing or cancelling my trip to Otay Mesa?

To find more details about changing or cancelling your trip to Otay Mesa, go to https://www.expedia.com/service/.

What is there to do in this San Diego neighborhood?

A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana, and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.

Recent reviews of Otay Mesa hotels

The Dana on Mission Bay

The Dana on Mission Bay

5/5 Excellent
"Love that it’s family friendly!"
A verified traveler stayed at The Dana on Mission Bay
Posted 12 hours ago
The Dana on Mission Bay