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Check prices for these dates

Tonight
Mar 11 - Mar 12
Tomorrow
Mar 12 - Mar 13
This weekend
Mar 13 - Mar 15
Next weekend
Mar 20 - Mar 22

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Our top choices for Otay Mesa hotels

Free buffet breakfast

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2.5 star property
Otay Mesa
8.0 out of 10, Very Good, (1,662 reviews)
"Clean, great breakfast, good service."
United States
Sara
The price is ￥20,403
￥23,209 total
includes taxes & fees
Mar 15 - Mar 16
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Free on-the-go breakfast

Quality Suites San Diego Otay Mesa

Quality Suites San Diego Otay Mesa
2.5 star property
Otay Mesa
7.0 out of 10, Good, (1,009 reviews)
"Great staff.. location close to the airport!"
United States
Vivian
The price is ￥17,010
￥19,349 total
includes taxes & fees
Apr 5 - Apr 6
Quality Suites San Diego Otay Mesa
Property amenity

Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG
3.5 star property
29.8 km from Otay Mesa
8.0 out of 10, Very Good, (1,028 reviews)
"Great stay"
United States
Viviann
The price is ￥15,974
￥18,424 total
includes taxes & fees
Apr 5 - Apr 6
Crowne Plaza San Diego - Mission Valley by IHG
Studio Suite, 1 King Bed with Sofa bed, Balcony | View from room

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
28.1 km from Otay Mesa
8.4 out of 10, Very Good, (3,370 reviews)
"Love this hotel will always stay here when I come to San Diego "
United States
Darlene
The price is ￥19,770
￥29,684 total
includes taxes & fees
Apr 2 - Apr 3
Sheraton San Diego Resort
Exterior

Valli Hi Motel

Valli Hi Motel
2.5 star property
7.9 km from Otay Mesa
8.4 out of 10, Very Good, (1,000 reviews)
"Excelente "
Mexico
Julio
Valli Hi Motel
3 outdoor pools, cabanas (surcharge), pool umbrellas

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
28.5 km from Otay Mesa
9.2 out of 10, Wonderful, (1,783 reviews)
"Very clean resort. "
United States
Petrina
Sycuan Casino Resort
Exterior

Motel 6 El Cajon, CA - San Diego

Motel 6 El Cajon, CA - San Diego
2.0 star property
27 km from Otay Mesa
7.4 out of 10, Good, (1,580 reviews)
"We only stayed one night but it was comfortable and clean "
United States
Brandy
The price is ￥10,342
￥11,400 total
includes taxes & fees
Mar 20 - Mar 21
Motel 6 El Cajon, CA - San Diego
Free continental breakfast

Best Western Chula Vista/Otay Valley Hotel

Best Western Chula Vista/Otay Valley Hotel
2.5 star property
7.1 km from Otay Mesa
7.8 out of 10, Good, (1,638 reviews)
"Clean rooms and the breakfast was amazing "
United States
Vanessa
The price is ￥16,322
￥17,954 total
includes taxes & fees
Mar 15 - Mar 16
Best Western Chula Vista/Otay Valley Hotel
3 bars/lounges, lobby lounge, cocktail bar, cocktail bar

Lafayette Hotel & Club

Lafayette Hotel & Club
4.0 star property
26.8 km from Otay Mesa
9.2 out of 10, Wonderful, (1,515 reviews)
"Stunning hotel, I could have stayed there all day looking at every little design detail. "
United States
Holly
The price is ￥36,219
￥41,562 total
includes taxes & fees
Mar 19 - Mar 20
Lafayette Hotel & Club
View from property

SpringHill Suites by Marriott Chula Vista Eastlake

SpringHill Suites by Marriott Chula Vista Eastlake
3.5 star property
10.5 km from Otay Mesa
9.6 out of 10, Exceptional, (592 reviews)
"Clean room and friendly staff "
United States
Michael
The price is ￥27,045
￥29,802 total
includes taxes & fees
Mar 23 - Mar 24
SpringHill Suites by Marriott Chula Vista Eastlake
Lobby sitting area

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
31.3 km from Otay Mesa
7.4 out of 10, Good, (4,205 reviews)
"Good location friendly staff"
United States
Anya
The price is ￥15,515
￥17,834 total
includes taxes & fees
Mar 23 - Mar 24
Wyndham Garden San Diego Near SeaWorld
Premium bedding, in-room safe, desk, laptop workspace

Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
16.9 km from Otay Mesa
9.2 out of 10, Wonderful, (3,747 reviews)
"My favorite place to stay"
United States
Rubidia
The price is ￥21,383
￥23,563 total
includes taxes & fees
Mar 15 - Mar 16
Best Western Plus Marina Gateway Hotel
Lobby

Comfort Inn Sea World Area

Comfort Inn Sea World Area
3.5 star property
30.8 km from Otay Mesa
8.6 out of 10, Excellent, (3,470 reviews)
"Nice beds and breakfast, really convenient "
Canada
Margarita
The price is ￥16,215
￥18,638 total
includes taxes & fees
Apr 6 - Apr 7
Comfort Inn Sea World Area
Superior Double Room Single Use, 2 Queen Beds, Non Smoking, City View | Terrace/patio

Ash&9th

Ash&9th
2.0 star property
24.7 km from Otay Mesa
8.2 out of 10, Very Good, (407 reviews)
"Great location… stuff was really friendly "
United States
Aurora
The price is ￥12,447
￥14,158 total
includes taxes & fees
Apr 7 - Apr 8
Ash&9th
Outdoor pool

Heritage Inn San Diego

Heritage Inn San Diego
2.0 star property
31.8 km from Otay Mesa
7.4 out of 10, Good, (1,316 reviews)
"Clean room, staff was great during check in and checking out. "
United States
Amber
The price is ￥9,475
￥10,891 total
includes taxes & fees
Mar 26 - Mar 27
Heritage Inn San Diego
Front of property

Heritage Inn La Mesa

Heritage Inn La Mesa
2.0 star property
24.3 km from Otay Mesa
7.0 out of 10, Good, (1,307 reviews)
"Very friendly at front desk I wish it was a little cheaper and I would stay the whole trip here"
United States
Haley
The price is ￥9,617
￥10,611 total
includes taxes & fees
Mar 18 - Mar 19
Heritage Inn La Mesa
Breakfast, lunch, dinner served; Mediterranean cuisine

Bahia Resort Hotel

Bahia Resort Hotel
3.5 star property
Central Mission Beach, 34.9 km from Otay Mesa
8.6 out of 10, Excellent, (1,907 reviews)
"Amazing place "
United States
Richard
The price is ￥26,580
￥39,392 total
includes taxes & fees
Apr 12 - Apr 13
Bahia Resort Hotel
Lobby

Best Western Americana Inn

Best Western Americana Inn
2.5 star property
8 km from Otay Mesa
9.0 out of 10, Wonderful, (1,228 reviews)
"Great stay"
United States
Elisa
The price is ￥18,687
￥21,256 total
includes taxes & fees
Mar 17 - Mar 18
Best Western Americana Inn
3 restaurants, breakfast, lunch, dinner served; Regional cuisine

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
25.7 km from Otay Mesa
8.4 out of 10, Very Good, (6,051 reviews)
"Great place to stay"
United States
David
The price is ￥24,064
￥33,404 total
includes taxes & fees
Mar 19 - Mar 20
Wyndham San Diego Bayside
Gazebo

Berkshire Motor Hotel

Berkshire Motor Hotel
2.5 star property
North Park, 26.7 km from Otay Mesa
8.4 out of 10, Very Good, (1,000 reviews)
"Clean, very chill easy check in"
United States
Susana
The price is ￥14,220
￥16,033 total
includes taxes & fees
Mar 15 - Mar 16
Berkshire Motor Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Otay Mesa

Find the best Otay Mesa areas and neighborhoods for the activities you enjoy most. Learn more about Otay Mesa
Learn more about Otay Mesa
Seaport Village featuring a church or cathedral

Downtown San Diego

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Pacific Beach Park showing surfing, swimming and rugged coastline

Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

Belmont Park showing rides

Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

Gaslamp Quarter featuring signage

Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

Ocean Beach

Ocean Beach

Ocean Beach is known for its stunning beaches, and with sights like Ocean Beach and Dog Beach, you won't get bored spending a day wandering around this part of San Diego.

Top Otay Mesa Hotel Reviews

Best Western Seven Seas

Best Western Seven Seas

4/10 Poor
"Need to update bedding. "
Bruce 1-night trip
Posted 1 hour ago
Best Western Seven Seas

Frequently asked questions

What's it like in Otay Mesa?
Otay Mesa is a neighborhood that travelers like for its beaches, restaurants, and shopping.
Where is the best hotel for a stay in Otay Mesa?
Based on Expedia customer reviews, Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG is the highest ranked property in Otay Mesa. This hotel offers free breakfast and an outdoor pool. Another top choice in the area is Quality Suites San Diego Otay Mesa.
If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Otay Mesa.
Where can I learn more about changing or cancelling my trip to Otay Mesa?
To find more details about changing or cancelling your trip to Otay Mesa, go to https://www.expedia.com/service/.
What is there to do in this San Diego neighborhood?
A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana, and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.

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