The Best Resorts & Hotels with Spas in Ortygia from ￥14,849 in 2026

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Our top choices for Ortygia hotels with a spa

A room with a bed, a mirror, and a wall with a mosaic.

1. Grand Hotel Ortigia Siracusa

Ortigia

Rejuvenating waterfront sanctuary offers spa treatments and a private beach, with a rooftop terrace overlooking Ortigia's historical charm.

￥44,632 total

includes taxes & fees

Dec 8 - Dec 9

A room with a bed, curtains, and a view of the sea through a balcony door.

2. EGEO - Ortigia

Ortigia

￥42,781 total

includes taxes & fees

Nov 9 - Nov 10

A reception area with a marble floor, a reception desk with a TV, and a glass table with chairs.

3. Ortea Palace Hotel, Sicily, Autograph Collection

Ortigia

Relax in waterfront luxury at this spa retreat with sauna, hot tub, and massage treatments.

￥45,419 total

includes taxes & fees

Nov 29 - Nov 30

A spa area with a mosaic-tiled bench, a framed picture on the wall, and a door in the background.

4. Domus Mariae Albergo

Ortigia

Seaside wellness sanctuary offers rejuvenating spa treatments and blissful hot tub soaks in the heart of Ortigia's historic district.

￥17,570 total

includes taxes & fees

Dec 9 - Dec 10

5. Domus Mariae Benessere

Ortigia

Unwind with waterfront serenity at this Ortigia retreat, featuring a full-service spa with couples' treatment rooms and a Turkish hammam.

￥19,351 total

includes taxes & fees

Nov 22 - Nov 23

A modern bar area with wooden pendant lighting, a reception desk, and a seating area with a round table.

6. Mercure Siracusa Prometeo

Neapolis

Luxurious rooftop pool meets rejuvenating spa experiences at this upscale Siracusa retreat.

￥18,693 total

includes taxes & fees

Nov 23 - Nov 24

A modern spa area with a pool, a seating area, and a stone cave-like structure.

7. UNA Hotels One Siracusa Wellness & SPA

Grottasanta

Unwind at an Art Deco waterfront hotel in Grottasanta with a full-service spa offering hydrotherapy treatments and a Turkish hammam.

￥18,989 total

includes taxes & fees

Nov 9 - Nov 10

A modern bathroom with a freestanding bathtub, a round table with a magazine, and a view of a pool and greenery.

8. Minareto

Syracuse

Relax in an Art Deco sanctuary with a private beach and outdoor spa treatments, creating a perfect blend of coastal elegance and wellness.

￥52,212 total

includes taxes & fees

Nov 16 - Nov 17

A bathroom with a marble floor, a white vanity with a mirror, and a green wall.

9. Casa Miranda Boutique

Santa Lucia

￥38,162 total

includes taxes & fees

Dec 8 - Dec 9

A spa area with a hot tub, a massage chair, and a massage table.

10. Wellness & Spa Hotel Principe di Fitalia

Syracuse

Immerse in this wellness oasis with spectacular spa treatments, outdoor pools, and dedicated staff for a therapeutic escape.

￥54,981 total

includes taxes & fees

Nov 14 - Nov 15

View all properties

Choose what matters most at spa hotels in Ortygia

Pool

Breakfast included

Top Ortygia Hotel Reviews

EGEO - Ortigia

Ortigia

10/10 Excellent

rafael

Domus Mariae Albergo

Ortigia

10/10 Excellent

This charming hotel is in a great location overlooking the sea and within easy walking distance of everything in historic Ortygia. Our room was spotlessly clean and came with a small balcony that overlooked the street and ancient church below. There is an amazing rooftop terrace, open to guests, where one can sunbathe or eat a meal overlooking the absolutely beautiful blue Mediterranean. The helpful staff assisted us as we found a nearby parking spot for our car and gave us a paper to put on the...

KellKat

Ortea Palace Hotel, Sicily, Autograph Collection

Ortigia

10/10 Excellent

Facundo

Domus Mariae Benessere

Ortigia

10/10 Excellent

Noelle

A courtyard with a round seating area, a wooden table with items, and a building with multiple doors and windows.

Borgo Pantano

Syracuse

10/10 Excellent

James

Wellness & Spa Hotel Principe di Fitalia

Syracuse

10/10 Excellent

Jeffrey

Mercure Siracusa Prometeo

Neapolis

10/10 Excellent

Very friendly reception with welcome drink in roof top bar. Very helpful staff including manager Signore Dino (as well as the owner always in the background). Modern and beautiful rooms with high quality equipment. Roof top swimming pool area as well as restaurant offering breathtaking views. Best breakfast buffet on our Sicily trip: fresh fruit, juices, breads, cakes, croissants, cheeses, Italian sausages. All coffee choices - espresso, cappuccino, lattes - available from 3 large automatic...

Annette

Minareto

Syracuse

10/10 Excellent

Is this one of the best hotels in the world?15 minutes from Siracusa, in a wonderful position facing the bay the hotel is in a beautiful carefully planned garden.The 90 rooms are spread in the garden, each a building with just ground floor. We had a large room for three and a large bathroom. Elegant and efficient, excellent bed and private balcony. The hotel has a reception and a restaurant building. All is close, 200m. Swimming pool. But the top are the two options for swimming and sunning: on...

Arnoldo

UNA Hotels One Siracusa Wellness & SPA

Grottasanta

10/10 Excellent

When we arrived we needed to change the room and they were very helpful with 2 options. We got the one facing the ocean. Breakfast was very good. I had to wash my car and one of the helpers at the reception drove with her motorcycle in front of me until we got the place. We used the gym and was very good. The helpers at the reception are young women and were excellent service. The top fllor (4) is an open terrace very nice to stay in the afternoon. The place was not dark at all as I read in...

Anonymous traveler