A coastal fortress with a stone wall and a tiled-roof building.

Find Luxury Hotels in Syracuse

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Syracuse Luxury Hotels

Tonight
Oct 7 - Oct 8
Tomorrow
Oct 8 - Oct 9
This weekend
Oct 9 - Oct 11
Next weekend
Oct 16 - Oct 18

Our top choices for Syracuse luxury hotels

A poolside area with lounge chairs and umbrellas, a clear blue pool, and a building with balconies.
A grand hallway with a marble floor, ornate columns, and a staircase leading to an upper level.
A terrace with a view of the sea and a cruise ship, featuring outdoor seating and potted cacti.
A spacious dining area with round tables and blue chairs, large windows offering a city view, and a wooden ceiling structure.

1. Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World
Ortigia
  • Discover the epitome of Mediterranean luxury steps from Ortigia's coastline at this spa-focused retreat with poolside indulgence.
￥101,994
￥113,965 total
includes taxes & fees
Oct 16 - Oct 17
Grand Hotel Des Ètrangers - The Leading Hotels of the World
A large, historic building with multiple floors, a prominent tower, and a waterfront marina with boats.
A balcony with a glass table and two red chairs, overlooking a coastal view with buildings and boats.
A balcony with a view of the sea and a cityscape, furnished with two chairs and a small table with a vase of flowers.
A grand atrium with a central column, ornate railings, and a large mural on the wall.

2. Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection
Ortigia
  • Mediterranean luxury awaits at this 5-star Syracuse hotel with spa, sauna, and two restaurants near Ortigia's beaches.
￥55,558
￥62,894 total
includes taxes & fees
Nov 1 - Nov 2
Ortea Palace Hotel, Sicily, Autograph Collection
A large swimming pool with a modern building in the background.
An outdoor dining area with tables and chairs, a pool, and palm trees in the background.
A woman relaxing in a spa bath with a modern design, including a ceiling with blue lighting and a tiled floor.
A sauna with wooden benches and a central stone pillar.

3. Wellness & Spa Hotel Principe di Fitalia

Wellness & Spa Hotel Principe di Fitalia
Syracuse
  • Sicilian spa escape boasts 2 outdoor pools and a serene full-service wellness center.
￥53,130
￥60,224 total
includes taxes & fees
Nov 6 - Nov 7
Wellness & Spa Hotel Principe di Fitalia
A balcony with a view of the sea, a cactus, and potted plants.
A poolside area with lounge chairs and umbrellas, a clear pool, and a building with multiple windows in the background.
A large, multi-story building with a symmetrical facade, arched windows, and a central entrance with a colorful awning.
A large, classical building with multiple windows and balconies, surrounded by a calm body of water with several yachts docked.

4. Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa
Ortigia
  • Experience luxury at grand hotel with spa services, private beach, and seaside dining in Ortigia.
￥48,779
￥55,438 total
includes taxes & fees
Nov 7 - Nov 8
Grand Hotel Ortigia Siracusa
An aerial view of a resort with multiple swimming pools, palm trees, and a clear view of the coastline.
A table set with breakfast items overlooking a coastal view.
A pathway lined with palm trees leading to a building with a red-tiled roof.
A modern bathroom with a freestanding bathtub, a small table with toiletries, and a view of the ocean.

5. Minareto

Minareto
Syracuse
  • Syracuse seaside splendor offers indulgent relaxation with private beach access, beachfront dining, and Art Deco elegance.
￥44,750
￥51,006 total
includes taxes & fees
Nov 7 - Nov 8
Minareto
A spa room with a large window, a hot tub, and two candles.
A courtyard with a stone pathway, palm trees, and potted plants.
A stone building with arched walkways and outdoor seating areas.
A spacious lobby with arched ceilings, a central round table with decorative items, and a modern chandelier.

6. Dimora Caiammari Luxury Hotel & Spa

Dimora Caiammari Luxury Hotel & Spa
Syracuse
  • Coastal luxury awaits at this five-star retreat offering a full-service spa, two outdoor pools, and Mediterranean dining near Fanusa Beach.
￥48,021
￥54,604 total
includes taxes & fees
Oct 25 - Oct 26
Dimora Caiammari Luxury Hotel & Spa
A rooftop terrace with lounge chairs, a hot tub, and a view of palm trees and buildings.
A multi-story building with a rooftop terrace, balconies, and a street view.
A modern hotel room with a stone wall, a staircase, a seating area with two chairs, a small table, and a desk with a phone and a lamp.
A multi-story building with a rooftop terrace featuring outdoor seating and a hot tub.

7. Caportigia Boutique Hotel

Caportigia Boutique Hotel
Santa Lucia
  • Elegant Mediterranean luxury, impeccable service, and fine dining near Ortigia await at this boutique Syracuse hotel.
￥22,097
￥26,088 total
includes taxes & fees
Nov 6 - Nov 7
Caportigia Boutique Hotel
A modern kitchen with grey cabinets, a marble backsplash, and a dining area with a long table and chairs.
A two-story house with a balcony, a covered patio, and a garden area.
A bedroom with a bed, a wardrobe, a window, and a wall-mounted picture.
A covered outdoor dining area with a table and chairs, a wooden ceiling, and a view of the surrounding landscape.

8. Villa Segesta holiday flat with terrace, WiFi and air conditioning

Villa Segesta holiday flat with terrace, WiFi and air conditioning
Tiche
￥95,164
￥104,023 total
includes taxes & fees
Oct 12 - Oct 13
Villa Segesta holiday flat with terrace, WiFi and air conditioning
An outdoor seating area with sofas, a table with candles, and lanterns.
A garden with a pool, lounge chairs, and a gazebo.
A dining area with stone walls, wooden beams, and tables set for dining.
A villa with a spacious patio, a well-maintained garden, and a view of the surrounding landscape.

9. Donna Coraly Country Boutique Hotel

Donna Coraly Country Boutique Hotel
Syracuse
￥43,673
￥49,821 total
includes taxes & fees
Oct 25 - Oct 26
Donna Coraly Country Boutique Hotel
A beachside restaurant with outdoor seating overlooking the sea, a clear sky, and a distant mountain range.
A room with a large window overlooking the sea, a bathtub, a table with a magazine, and a towel hanging on the wall.
A woman in a red swimsuit sitting in a bathtub with a view of the ocean. There is a bottle of wine, two glasses, and a bowl of fruit on the edge of the bathtub.
A balcony with a view of the ocean, a glass shower enclosure, and a table with fruits and drinks.

10. White Bay Resort

White Bay Resort
Syracuse
￥24,871
￥29,139 total
includes taxes & fees
Oct 15 - Oct 16
White Bay Resort
View all properties

Top Syracuse Hotel Reviews

Grand Hotel Villa Politi

Grand Hotel Villa Politi

8/10 Good
"Large older hotel, built in 1862 but renovated. Quiet. Situated in an historic park. Many bus tours stay here. Rooms are clean, fairly large and adequately equipped. Bed needs to be upgraded, mattress is hard and uncomfortable. Shower is in the bathtub, you need to step over the bathtub to access. Limited views from rooms. Convenient city bus stop not far from the main gate to access downtown and Ortigia. Free parking for those with rental cars. Breakfast is okay, typical large group buffet-style with chaotic frenzy to grab fresh items in limited quantities. Restaurant for dinner is okay but overpriced. Much better dining options in town."
Richard 4-night trip
Posted 15 hours ago
Grand Hotel Villa Politi
Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel

10/10 Excellent
"Very nice place! Staff was wonderful and helpful. Will stay there again."
Hitendra 1-night trip
Posted 20 hours ago
Algila' Ortigia Charme Hotel
Hotel Posta

Hotel Posta

10/10 Excellent
"Super emplacement. Parking publique juste à côté. Notre chambre était petit , mais coquette et une belle vue sur la mer. Nous avons aimé. La terrasse sur le toit pour déjeuner, est super."
Katy 2-night trip
Posted 4 days ago
Hotel Posta
Grande Albergo Alfeo

Grande Albergo Alfeo

10/10 Excellent
"We enjoyed our stay"
Anna 3-night trip
Posted 9 days ago
Grande Albergo Alfeo
Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection

10/10 Excellent
"El mejor de Ortigia"
William 2-night trip
Posted 3 weeks ago
Palazzo Artemide - VRetreats, SLH Collection
Eureka Palace Hotel Spa

Eureka Palace Hotel Spa

8/10 Good
"The rooms were spacious and clean. The spa was also very good and well maintained"
IKECHUKWU 6-night trip
Posted 1 month ago
Eureka Palace Hotel Spa

Frequently asked questions

Are you searching for a great accommodation for your luxury holiday in Syracuse?
Travel to Fontanarossa Airport (CTA) Airport or Vincenzo Magliocco Airport (CIY) Airport, and then treat yourself to a stay at one of 9 Syracuse luxury hotels. While you're visiting, you might want to think about enjoying the ruins and sightseeing, which Syracuse is known for.
What's the best high-end place to stay in Syracuse?
Ortea Palace Hotel, Sicily, Autograph Collection is a luxury hotel with 2 restaurants and a full-service spa, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Grand Hotel Ortigia Siracusa and Grand Hotel Des Ètrangers - The Leading Hotels of the World are other upscale choices for your vacation.
How many luxury hotels will I be able to find in Syracuse?
Lie in the lap of luxury during your getaway to Syracuse in one of Expedia's 9 luxury hotels.
When can I expect good weather in Syracuse?
Planning for the weather is a good way to make your trip to Syracuse relaxing and enjoyable, especially when you're splurging. The hottest months are usually August and July with an average temp of 78°F, while the coldest months are February and January with an average of 56°F. Average annual precipitation for Syracuse is 26 inches.
What's there to see and do in Syracuse?
Experience all that Syracuse has to offer when you visit Temple of Apollo, Lungomare di Ortigia, and Piazza del Duomo. If you have a little extra time during your trip, you might want to check out Cathedral of Syracuse and Porto Piccolo.
How can I get around Syracuse?
It's easier to get around town in style when you know your options. To explore the surrounding area, ride one of the trains from Syracuse Station or Targia Station.

Explore a world of travel with Expedia