A coastal fortress with a stone wall and a tiled-roof building.

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Check availability on Syracuse Luxury Hotels

This weekend
Oct 30 - Nov 1
Next weekend
Nov 6 - Nov 8

Our top choices for Syracuse luxury hotels

A poolside area with lounge chairs and umbrellas, a clear blue pool, and a building with balconies.

1. Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World
5.0 star property
Ortigia
9.2 out of 10, Wonderful, (111 reviews)
  • cleanliness
    Discover the epitome of Mediterranean luxury steps from Ortigia's coastline at this spa-focused retreat with poolside indulgence.
The price is ￥101,152
￥113,024 total
includes taxes & fees
Oct 30 - Oct 31
Grand Hotel Des Ètrangers - The Leading Hotels of the World
A spa room with a large window, a hot tub, and two candles.

2. Dimora Caiammari Luxury Hotel & Spa

Dimora Caiammari Luxury Hotel & Spa
5.0 star property
Syracuse
9.4 out of 10, Exceptional, (223 reviews)
  • cleanliness
    Coastal luxury awaits at this five-star retreat offering a full-service spa, two outdoor pools, and Mediterranean dining near Fanusa Beach.
The price is ￥50,609
￥57,427 total
includes taxes & fees
Nov 1 - Nov 2
Dimora Caiammari Luxury Hotel & Spa
A large, historic building with multiple floors, a prominent tower, and a waterfront marina with boats.

3. Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection
5.0 star property
Ortigia
9.2 out of 10, Wonderful, (286 reviews)
  • cleanliness
    Mediterranean luxury awaits at this 5-star Syracuse hotel with spa, sauna, and two restaurants near Ortigia's beaches.
The price is ￥45,879
￥52,224 total
includes taxes & fees
Nov 8 - Nov 9
Ortea Palace Hotel, Sicily, Autograph Collection
A large swimming pool with a modern building in the background.

4. Wellness & Spa Hotel Principe di Fitalia

Wellness & Spa Hotel Principe di Fitalia
5.0 star property
Syracuse
9.4 out of 10, Exceptional, (99 reviews)
  • cleanliness
    Sicilian spa escape boasts 2 outdoor pools and a serene full-service wellness center.
The price is ￥51,603
￥58,520 total
includes taxes & fees
Nov 17 - Nov 18
Wellness & Spa Hotel Principe di Fitalia
A balcony with a view of the sea, a cactus, and potted plants.

5. Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa
5.0 star property
Ortigia
9.0 out of 10, Wonderful, (640 reviews)
  • cleanliness
    Experience luxury at grand hotel with spa services, private beach, and seaside dining in Ortigia.
The price is ￥38,359
￥43,952 total
includes taxes & fees
Nov 16 - Nov 17
Grand Hotel Ortigia Siracusa
An aerial view of a resort with multiple swimming pools, palm trees, and a clear view of the coastline.

6. Minareto

Minareto
5.0 star property
Syracuse
8.8 out of 10, Excellent, (282 reviews)
  • cleanliness
    Syracuse seaside splendor offers indulgent relaxation with private beach access, beachfront dining, and Art Deco elegance.
The price is ￥44,652
￥50,874 total
includes taxes & fees
Nov 7 - Nov 8
Minareto
A rooftop terrace with lounge chairs, a hot tub, and a view of palm trees and buildings.

7. Caportigia Boutique Hotel

Caportigia Boutique Hotel
5.0 star property
Santa Lucia
9.2 out of 10, Wonderful, (300 reviews)
  • cleanliness
    Elegant Mediterranean luxury, impeccable service, and fine dining near Ortigia await at this boutique Syracuse hotel.
The price is ￥21,806
￥25,744 total
includes taxes & fees
Nov 26 - Nov 27
Caportigia Boutique Hotel
A modern kitchen with grey cabinets, a marble backsplash, and a dining area with a long table and chairs.

8. Villa Segesta holiday flat with terrace, WiFi and air conditioning

Villa Segesta holiday flat with terrace, WiFi and air conditioning
Tiche
9.6 out of 10, Exceptional, (5 reviews)
The price is ￥94,379
￥103,165 total
includes taxes & fees
Oct 30 - Oct 31
Villa Segesta holiday flat with terrace, WiFi and air conditioning
An outdoor seating area with sofas, a table with candles, and lanterns.

9. Donna Coraly Country Boutique Hotel

Donna Coraly Country Boutique Hotel
Syracuse
9.8 out of 10, Exceptional, (12 reviews)
The price is ￥43,098
￥49,165 total
includes taxes & fees
Oct 29 - Oct 30
Donna Coraly Country Boutique Hotel
A beachside restaurant with outdoor seating overlooking the sea, a clear sky, and a distant mountain range.

10. White Bay Resort

White Bay Resort
Syracuse
8.8 out of 10, Excellent, (53 reviews)
The price is ￥24,358
￥28,550 total
includes taxes & fees
Nov 13 - Nov 14
White Bay Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Syracuse Hotel Reviews

Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa

10/10 Excellent
"I enjoyed four unforgettable days exploring beautiful Ortigia -staying at the Grand Hotel Ortigia, which is a 5-star luxury hotel overlooking the harbor. It is just a short stroll to the must-see landmarks such as the ruins of the Temple of Apollo, the Aretusa Fountain, and the renowned Cathedral of Syracuse. it was built in 1890 and was completely renovated while preserving its classic old-world charm with marble floors, Corinthian columns, and beautiful art-filled common areas. They have an upscale rooftop restaurant and lounge on the third floor, which serves a sumptuous breakfast buffet and has great outdoor seating with spectacular views. I went up to the terrace one evening to enjoy the sunset with an Aperol Spritz and some nibbles and, after the sun went down, an exceptionally talented young man beautifully played his violin serenading the guests. Parking in the old city is a challenge, and not for the faint of heart. But the hotel does have a small lot nearby, but which seemed to stay full and was hard to find. With the helpful staff, I was able to register my rental car to allow me to drive to hotel which is in the restricted tourist zone and I moved my car to their lot one evening once the crowds had dissipated a bit. The staff couldn’t have been more helpful and even helped arrange a small group boat tour. This hotel truly deserves its name the Grand Hotel Ortigia Siracusa!"
Robert 4-night trip
Posted 5 hours ago
Grand Hotel Ortigia Siracusa

Frequently asked questions

Are you searching for a great accommodation for your luxury holiday in Syracuse?
Travel to Fontanarossa Airport (CTA) Airport or Vincenzo Magliocco Airport (CIY) Airport, and then treat yourself to a stay at one of 9 Syracuse luxury hotels. While you're visiting, you might want to think about enjoying the ruins and sightseeing, which Syracuse is known for.
What's the best high-end place to stay in Syracuse?
Ortea Palace Hotel, Sicily, Autograph Collection is a luxury hotel with 2 restaurants and a full-service spa, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Grand Hotel Ortigia Siracusa and Grand Hotel Des Ètrangers - The Leading Hotels of the World are other upscale choices for your vacation.
How many luxury hotels will I be able to find in Syracuse?
Lie in the lap of luxury during your getaway to Syracuse in one of Expedia's 9 luxury hotels.
When can I expect good weather in Syracuse?
Planning for the weather is a good way to make your trip to Syracuse relaxing and enjoyable, especially when you're splurging. The hottest months are usually August and July with an average temp of 78°F, while the coldest months are February and January with an average of 56°F. Average annual precipitation for Syracuse is 26 inches.
What's there to see and do in Syracuse?
Experience all that Syracuse has to offer when you visit Temple of Apollo, Lungomare di Ortigia, and Piazza del Duomo. If you have a little extra time during your trip, you might want to check out Cathedral of Syracuse and Porto Piccolo.
How can I get around Syracuse?
It's easier to get around town in style when you know your options. To explore the surrounding area, ride one of the trains from Syracuse Station or Targia Station.