A coastal fortress with a stone wall and a tiled-roof building.

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Check availability on Syracuse Luxury Hotels

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Oct 2 - Oct 3
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Oct 3 - Oct 4
This weekend
Oct 2 - Oct 4
Next weekend
Oct 9 - Oct 11

Our top choices for Syracuse luxury hotels

A poolside area with lounge chairs and umbrellas, a clear blue pool, and a building with balconies.
A spacious dining area with round tables and blue chairs, large windows offering a city view, and a wooden ceiling structure.
A terrace with a view of the sea and a cruise ship, featuring outdoor seating and potted cacti.
A grand hallway with a marble floor, ornate columns, and a staircase leading to an upper level.

1. Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World
Ortigia
  • Discover the epitome of Mediterranean luxury steps from Ortigia's coastline at this spa-focused retreat with poolside indulgence.
￥98,990
￥110,666 total
includes taxes & fees
Oct 19 - Oct 20
Grand Hotel Des Ètrangers - The Leading Hotels of the World
A large, historic building with multiple floors, a prominent tower, and a waterfront marina with boats.
A balcony with a glass table and two red chairs, overlooking a coastal view with buildings and boats.
A grand atrium with a central column, ornate railings, and a large mural on the wall.
A balcony with a view of the sea and a cityscape, furnished with two chairs and a small table with a vase of flowers.

2. Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection
Ortigia
  • Mediterranean luxury awaits at this 5-star Syracuse hotel with spa, sauna, and two restaurants near Ortigia's beaches.
￥55,443
￥62,765 total
includes taxes & fees
Nov 1 - Nov 2
Ortea Palace Hotel, Sicily, Autograph Collection
A large swimming pool with a modern building in the background.
A woman relaxing in a spa bath with a modern design, including a ceiling with blue lighting and a tiled floor.
A beach with clear turquoise water, sandy shore, and sparse vegetation.
A sauna with wooden benches and a central stone pillar.

3. Wellness & Spa Hotel Principe di Fitalia

Wellness & Spa Hotel Principe di Fitalia
Syracuse
  • Sicilian spa escape boasts 2 outdoor pools and a serene full-service wellness center.
￥66,099
￥74,486 total
includes taxes & fees
Oct 23 - Oct 24
Wellness & Spa Hotel Principe di Fitalia
A spa room with a large window, a hot tub, and two candles.
A stone building with arched walkways and outdoor seating areas.
A courtyard with a stone pathway, palm trees, and potted plants.
A spacious lobby with arched ceilings, a central round table with decorative items, and a modern chandelier.

4. Dimora Caiammari Luxury Hotel & Spa

Dimora Caiammari Luxury Hotel & Spa
Syracuse
  • Coastal luxury awaits at this five-star retreat offering a full-service spa, two outdoor pools, and Mediterranean dining near Fanusa Beach.
￥47,922
￥54,492 total
includes taxes & fees
Oct 21 - Oct 22
Dimora Caiammari Luxury Hotel & Spa
A rooftop terrace with lounge chairs, a hot tub, and a view of palm trees and buildings.
A multi-story building with a rooftop terrace featuring outdoor seating and a hot tub.
A modern hotel room with a stone wall, a staircase, a seating area with two chairs, a small table, and a desk with a phone and a lamp.
A modern hotel room with a stone accent wall, a grey sofa, a large mirror, a chandelier, and a neatly made bed with rolled towels.

5. Caportigia Boutique Hotel

Caportigia Boutique Hotel
Santa Lucia
  • Elegant Mediterranean luxury, impeccable service, and fine dining near Ortigia await at this boutique Syracuse hotel.
￥28,271
￥32,875 total
includes taxes & fees
Oct 29 - Oct 30
Caportigia Boutique Hotel
An outdoor seating area with sofas, a table with candles, and lanterns.
A dining area with stone walls, wooden beams, and tables set for dining.
A garden with a pool, lounge chairs, and a gazebo.
A villa with a spacious patio, a well-maintained garden, and a view of the surrounding landscape.

6. Donna Coraly Country Boutique Hotel

Donna Coraly Country Boutique Hotel
Syracuse
￥43,662
￥49,805 total
includes taxes & fees
Oct 29 - Oct 30
Donna Coraly Country Boutique Hotel
A beachside restaurant with outdoor seating overlooking the sea, a clear sky, and a distant mountain range.
A woman in a red swimsuit sitting in a bathtub with a view of the ocean. There is a bottle of wine, two glasses, and a bowl of fruit on the edge of the bathtub.
A balcony with a view of the ocean, a glass shower enclosure, and a table with fruits and drinks.
A room with a large window overlooking the sea, a bathtub, a table with a magazine, and a towel hanging on the wall.

7. White Bay Resort

White Bay Resort
Syracuse
￥26,425
￥30,844 total
includes taxes & fees
Oct 28 - Oct 29
White Bay Resort
A poolside area with lounge chairs and umbrellas, surrounded by palm trees and a building with a tiled roof.
A beach with rows of sun loungers and umbrellas, a clear sky, and the ocean in the background.
A hotel room with a bed, green sofa, and a table with candles. There is a balcony with a table and chairs, and a view of greenery and a palm tree.
A wine cellar with a long wooden table and chairs, surrounded by shelves of wine bottles.

8. Il San Corrado di Noto Luxury Resort

Il San Corrado di Noto Luxury Resort
Noto
  • Mediterranean luxury resort with private beach access, full-service spa, and poolside dining in rural Sicily.
￥202,055
￥224,038 total
includes taxes & fees
Oct 19 - Oct 20
Il San Corrado di Noto Luxury Resort
A luxurious hotel with a reflective pool, elegant outdoor seating, and a well-lit interior.
A cozy room with a cushioned bench, wooden furniture, and potted plants.
An arched entrance with a wooden door, surrounded by stone walls and trees.
An outdoor seating area with wicker furniture and umbrellas, stone columns, and a garden.

9. Dimora delle Balze

Dimora delle Balze
Noto
  • Sicilian countryside inn elevates relaxation with full-service spa treatments and poolside serenity.
￥135,402
￥150,008 total
includes taxes & fees
Oct 7 - Oct 8
Dimora delle Balze
A bedroom with a large window, a bed, and a view of pink flowers outside.
A modern building with a wooden sloped roof, large glass windows, and outdoor seating.
A modern building with large windows, surrounded by olive trees and a dry landscape.
A dining area with a table set for two, a view of the countryside, and a large window.

10. Country House Villadorata

Country House Villadorata
Noto
￥114,417
￥126,928 total
includes taxes & fees
Oct 3 - Oct 4
Country House Villadorata
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Top Syracuse Hotel Reviews

Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World

10/10 Excellent
"Amazing pool beautiful hotel"
Steven 2-night trip
Posted 9 hours ago
Grand Hotel Des Ètrangers - The Leading Hotels of the World
Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel

10/10 Excellent
"Beautiful hotel with wonderful hospitality We absolutely loved our stay at Hotel Algilà Ortigia Charme. From the moment we arrived, the staff were warm, friendly and genuinely welcoming. The hotel is full of Sicilian character and charm, and its location in Ortigia was perfect for exploring on foot. Our room was comfortable and beautifully suited to the character of the hotel, and the staff were always happy to help with recommendations and anything we needed. After travelling throughout Sicily for two weeks, what stood out most was the genuine hospitality. We felt like valued guests, not just another reservation. Algilà was exactly what we hoped for from a Sicilian hotel — charming, personal and welcoming. We would happily stay here again and highly recommend it to anyone visiting Ortigia!"
Sarah 3-night trip
Posted 2 days ago
Algila' Ortigia Charme Hotel
Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa

8/10 Good
"The hotel is conveniently located and balcony restaurant and bar had a great view."
SEAN 3-night trip
Posted 3 days ago
Grand Hotel Ortigia Siracusa
Grand Hotel Villa Politi

Grand Hotel Villa Politi

10/10 Excellent
"Nice hotel, good breakfast, beautiful pool, decent rooms, helpful staff. Free parking is a plus. Easy to access Ortigia by car and easy to access local beaches by car."
Peter 3-night trip
Posted 3 days ago
Grand Hotel Villa Politi
Grande Albergo Alfeo

Grande Albergo Alfeo

10/10 Excellent
"We enjoyed our stay"
Anna 3-night trip
Posted 3 days ago
Grande Albergo Alfeo
Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection

10/10 Excellent
"El mejor de Ortigia"
William 2-night trip
Posted 2 weeks ago
Palazzo Artemide - VRetreats, SLH Collection
Eureka Palace Hotel Spa

Eureka Palace Hotel Spa

8/10 Good
"The rooms were spacious and clean. The spa was also very good and well maintained"
IKECHUKWU 6-night trip
Posted 1 month ago
Eureka Palace Hotel Spa

Frequently asked questions

Are you searching for a great accommodation for your luxury holiday in Syracuse?
Travel to Fontanarossa Airport (CTA) Airport or Vincenzo Magliocco Airport (CIY) Airport, and then treat yourself to a stay at one of 9 Syracuse luxury hotels. While you're visiting, you might want to think about enjoying the ruins and sightseeing, which Syracuse is known for.
What's the best high-end place to stay in Syracuse?
Ortea Palace Hotel, Sicily, Autograph Collection is a luxury hotel with 2 restaurants and a full-service spa, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Grand Hotel Ortigia Siracusa and Grand Hotel Des Ètrangers - The Leading Hotels of the World are other upscale choices for your vacation.
How many luxury hotels will I be able to find in Syracuse?
Lie in the lap of luxury during your getaway to Syracuse in one of Expedia's 9 luxury hotels.
When can I expect good weather in Syracuse?
Planning for the weather is a good way to make your trip to Syracuse relaxing and enjoyable, especially when you're splurging. The hottest months are usually August and July with an average temp of 78°F, while the coldest months are February and January with an average of 56°F. Average annual precipitation for Syracuse is 26 inches.
What's there to see and do in Syracuse?
Experience all that Syracuse has to offer when you visit Temple of Apollo, Lungomare di Ortigia, and Piazza del Duomo. If you have a little extra time during your trip, you might want to check out Cathedral of Syracuse and Porto Piccolo.
How can I get around Syracuse?
It's easier to get around town in style when you know your options. To explore the surrounding area, ride one of the trains from Syracuse Station or Targia Station.

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