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Our top choices for Syracuse luxury hotels

Exterior

Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection
5.0 star property
Ortigia
9.4 out of 10, Exceptional, (263 reviews)
  • cleanliness
    Mediterranean luxury awaits at this 5-star Syracuse hotel with spa, sauna, and two restaurants near Ortigia's beaches.
The price is ￥80,586
￥90,491 total
includes taxes & fees
May 23 - May 24
Ortea Palace Hotel, Sicily, Autograph Collection
Seasonal outdoor pool, pool umbrellas, sun loungers

Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World
5.0 star property
Ortigia
9.6 out of 10, Exceptional, (77 reviews)
  • cleanliness
    Discover the epitome of Mediterranean luxury steps from Ortigia's coastline at this spa-focused retreat with poolside indulgence.
The price is ￥86,039
￥96,489 total
includes taxes & fees
Jun 4 - Jun 5
Grand Hotel Des Ètrangers - The Leading Hotels of the World
Sports facility

Wellness & Spa Hotel Principe di Fitalia

Wellness & Spa Hotel Principe di Fitalia
5.0 star property
Syracuse
9.6 out of 10, Exceptional, (94 reviews)
  • cleanliness
    Sicilian spa escape boasts 2 outdoor pools and a serene full-service wellness center.
The price is ￥55,851
￥63,283 total
includes taxes & fees
May 18 - May 19
Wellness & Spa Hotel Principe di Fitalia
Exterior

Minareto

Minareto
5.0 star property
Syracuse
8.8 out of 10, Excellent, (269 reviews)
  • cleanliness
    Syracuse seaside splendor offers indulgent relaxation with private beach access, beachfront dining, and Art Deco elegance.
The price is ￥51,645
￥60,503 total
includes taxes & fees
Jun 3 - Jun 4
Minareto
Front of property - evening/night

Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel
4.0 star property
Ortigia
9.6 out of 10, Exceptional, (952 reviews)
  • cleanliness
    Historic charm meets seaside luxury in Syracuse with private balconies, rainfall showers, and sea-view breakfast.
The price is ￥63,462
￥71,655 total
includes taxes & fees
May 29 - May 30
Algila' Ortigia Charme Hotel
Bicycling

Charme Hotel Henry's House

Charme Hotel Henry's House
4.0 star property
Ortigia
9.6 out of 10, Exceptional, (327 reviews)
  • cleanliness
    Luxurious Mediterranean retreat offers memory foam beds, designer toiletries, and sea-view rooftop terrace in Ortigia.
The price is ￥56,572
￥64,077 total
includes taxes & fees
May 12 - May 13
Charme Hotel Henry's House
Front of property

Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection
4.0 star property
Ortigia
9.4 out of 10, Exceptional, (669 reviews)
  • cleanliness
    Relax in a grand Beaux Arts hotel in Ortigia, where upscale comfort meets historic charm steps from Syracuse Cathedral.
The price is ￥66,694
￥75,210 total
includes taxes & fees
May 31 - Jun 1
Palazzo Artemide - VRetreats, SLH Collection
Sauna, hot tub, Turkish bath, body treatments, body scrubs, facials

Dimora Caiammari Luxury Hotel & Spa

Dimora Caiammari Luxury Hotel & Spa
5.0 star property
Syracuse
9.4 out of 10, Exceptional, (213 reviews)
  • cleanliness
    Coastal luxury awaits at this five-star retreat offering a full-service spa, two outdoor pools, and Mediterranean dining near Fanusa Beach.
The price is ￥51,676
￥58,690 total
includes taxes & fees
May 12 - May 13
Dimora Caiammari Luxury Hotel & Spa
Terrace/patio

Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa
5.0 star property
Ortigia
9.0 out of 10, Wonderful, (590 reviews)
  • cleanliness
    Experience luxury at grand hotel with spa services, private beach, and seaside dining in Ortigia.
The price is ￥48,412
￥55,101 total
includes taxes & fees
May 25 - May 26
Grand Hotel Ortigia Siracusa
Rooftop terrace

Caportigia Boutique Hotel

Caportigia Boutique Hotel
5.0 star property
Santa Lucia
9.4 out of 10, Exceptional, (274 reviews)
  • cleanliness
    Elegant Mediterranean luxury, impeccable service, and fine dining near Ortigia await at this boutique Syracuse hotel.
The price is ￥32,679
￥37,794 total
includes taxes & fees
May 26 - May 27
Caportigia Boutique Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Syracuse Hotel Reviews

Grande Albergo Alfeo

Grande Albergo Alfeo

6/10 Okay
"Breakfast menu fine. The air conditions was great. The front desk staff was uninterested and not interested in welcoming anyone."
keith 2-night trip
Posted 1 day ago
Grande Albergo Alfeo

Frequently asked questions

Are you searching for a great accommodation for your luxury holiday in Syracuse?
Travel to Fontanarossa Airport (CTA) Airport or Vincenzo Magliocco Airport (CIY) Airport, and then treat yourself to a stay at one of 11 Syracuse luxury hotels. While you're visiting, you might want to think about enjoying the ruins and sightseeing, which Syracuse is known for.
What's the best high-end place to stay in Syracuse?
Grand Hotel Ortigia Siracusa is a luxury hotel with a private beach and spa services, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Ortea Palace Hotel, Sicily, Autograph Collection and Grand Hotel Des Ètrangers - The Leading Hotels of the World are other upscale choices for your vacation.
How many luxury hotels will I be able to find in Syracuse?
Lie in the lap of luxury during your getaway to Syracuse in one of Expedia's 11 luxury hotels.
When can I expect good weather in Syracuse?
Planning for the weather is a good way to make your trip to Syracuse relaxing and enjoyable, especially when you're splurging. The hottest months are usually August and July with an average temp of 78°F, while the coldest months are February and January with an average of 56°F. Average annual precipitation for Syracuse is 26 inches.
What's there to see and do in Syracuse?
Experience all that Syracuse has to offer when you visit Temple of Apollo, Lungomare di Ortigia, and Piazza del Duomo. If you have a little extra time during your trip, you might want to check out Cathedral of Syracuse and Teatro dei Pupi.
How can I get around Syracuse?
It's easier to get around town in style when you know your options. To explore the surrounding area, ride one of the trains from Syracuse Station or Targia Station.