A coastal fortress with a stone wall and a tiled-roof building.

Find Luxury Hotels in Syracuse

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Syracuse Luxury Hotels

Tonight
Oct 25 - Oct 26
Tomorrow
Oct 26 - Oct 27
Next weekend
Oct 30 - Nov 1
In two weeks
Nov 6 - Nov 8

Our top choices for Syracuse luxury hotels

A poolside area with lounge chairs and umbrellas, a clear blue pool, and a building with balconies.
A grand hallway with a marble floor, ornate columns, and a staircase leading to an upper level.
A terrace with a view of the sea and a cruise ship, featuring outdoor seating and potted cacti.
A spacious dining area with round tables and blue chairs, large windows offering a city view, and a wooden ceiling structure.

1. Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World
Ortigia
  • Discover the epitome of Mediterranean luxury steps from Ortigia's coastline at this spa-focused retreat with poolside indulgence.
￥101,152
￥113,024 total
includes taxes & fees
Oct 29 - Oct 30
Grand Hotel Des Ètrangers - The Leading Hotels of the World
A spa room with a large window, a hot tub, and two candles.
A courtyard with a stone pathway, palm trees, and potted plants.
A stone building with arched walkways and outdoor seating areas.
A spacious living room with a high ceiling, white sofas, a coffee table, and a large mirror.

2. Dimora Caiammari Luxury Hotel & Spa

Dimora Caiammari Luxury Hotel & Spa
Syracuse
  • Coastal luxury awaits at this five-star retreat offering a full-service spa, two outdoor pools, and Mediterranean dining near Fanusa Beach.
￥50,609
￥57,427 total
includes taxes & fees
Nov 1 - Nov 2
Dimora Caiammari Luxury Hotel & Spa
A large, historic building with multiple floors, a prominent tower, and a waterfront marina with boats.
A balcony with a view of the sea and a cityscape, furnished with two chairs and a small table with a vase of flowers.
A grand atrium with a central column, ornate railings, and a large mural on the wall.
A balcony with a glass table and two red chairs, overlooking a coastal view with buildings and boats.

3. Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection
Ortigia
  • Mediterranean luxury awaits at this 5-star Syracuse hotel with spa, sauna, and two restaurants near Ortigia's beaches.
￥45,879
￥52,224 total
includes taxes & fees
Nov 8 - Nov 9
Ortea Palace Hotel, Sicily, Autograph Collection
A large swimming pool with a modern building in the background.
A beach with clear turquoise water, sandy shore, and sparse vegetation.
A sauna with wooden benches and a central stone pillar.
A woman relaxing in a spa bath with a modern design, including a ceiling with blue lighting and a tiled floor.

4. Wellness & Spa Hotel Principe di Fitalia

Wellness & Spa Hotel Principe di Fitalia
Syracuse
  • Sicilian spa escape boasts 2 outdoor pools and a serene full-service wellness center.
￥51,603
￥58,520 total
includes taxes & fees
Nov 17 - Nov 18
Wellness & Spa Hotel Principe di Fitalia
A balcony with a view of the sea, a cactus, and potted plants.
A dining area with a table set for two, overlooking a coastal view.
A large, classical building with multiple windows and balconies, surrounded by a calm body of water with several yachts docked.
A poolside area with lounge chairs and umbrellas, a clear pool, and a building with multiple windows in the background.

5. Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa
Ortigia
  • Experience luxury at grand hotel with spa services, private beach, and seaside dining in Ortigia.
￥38,359
￥43,952 total
includes taxes & fees
Nov 24 - Nov 25
Grand Hotel Ortigia Siracusa
An aerial view of a resort with multiple swimming pools, palm trees, and a clear view of the coastline.
A modern bathroom with a freestanding bathtub, a round table with a magazine, and a view of a pool and greenery.
A table set with breakfast items overlooking a coastal view.
A modern bathroom with a freestanding bathtub, a small table with toiletries, and a view of the ocean.

6. Minareto

Minareto
Syracuse
  • Syracuse seaside splendor offers indulgent relaxation with private beach access, beachfront dining, and Art Deco elegance.
￥44,652
￥50,874 total
includes taxes & fees
Nov 8 - Nov 9
Minareto
A rooftop terrace with lounge chairs, a hot tub, and a view of palm trees and buildings.
A modern hotel room with a stone wall, a staircase, a seating area with two chairs, a small table, and a desk with a phone and a lamp.
A multi-story building with a rooftop terrace, balconies, and a street view.
A modern hotel room with a stone accent wall, a grey sofa, a large mirror, a chandelier, and a neatly made bed with rolled towels.

7. Caportigia Boutique Hotel

Caportigia Boutique Hotel
Santa Lucia
  • Elegant Mediterranean luxury, impeccable service, and fine dining near Ortigia await at this boutique Syracuse hotel.
￥21,806
￥25,744 total
includes taxes & fees
Nov 25 - Nov 26
Caportigia Boutique Hotel
A modern kitchen with grey cabinets, a marble backsplash, and a dining area with a long table and chairs.
A modern dining area with a table set for four, a decorative bowl centerpiece, and a view into a living area with a sofa and a window.
A bedroom with a bed, a wardrobe, a window, and a wall-mounted picture.
A covered outdoor dining area with a table and chairs, a wooden ceiling, and a view of the surrounding landscape.

8. Villa Segesta holiday flat with terrace, WiFi and air conditioning

Villa Segesta holiday flat with terrace, WiFi and air conditioning
Tiche
￥89,660
￥98,446 total
includes taxes & fees
Oct 26 - Oct 27
Villa Segesta holiday flat with terrace, WiFi and air conditioning
An outdoor seating area with sofas, a table with candles, and lanterns.
A villa with a spacious patio, a well-maintained garden, and a view of the surrounding landscape.
A garden with a pool, lounge chairs, and a gazebo.
A living room with a sofa, a fireplace, a television, and a bookshelf.

9. Donna Coraly Country Boutique Hotel

Donna Coraly Country Boutique Hotel
Syracuse
￥43,098
￥49,165 total
includes taxes & fees
Oct 26 - Oct 27
Donna Coraly Country Boutique Hotel
A beachside restaurant with outdoor seating overlooking the sea, a clear sky, and a distant mountain range.
A woman in a red swimsuit sitting in a bathtub with a view of the ocean. There is a bottle of wine, two glasses, and a bowl of fruit on the edge of the bathtub.
A balcony with a view of the ocean, a glass shower enclosure, and a table with fruits and drinks.
A beach with clear shallow waters, a sandy shore, and a distant pier with buildings.

10. White Bay Resort

White Bay Resort
Syracuse
￥24,358
￥28,550 total
includes taxes & fees
Nov 13 - Nov 14
White Bay Resort
View all properties

Top Syracuse Hotel Reviews

Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel

10/10 Excellent
"Great location in historical area of Siracusa. Right across from water. Great bar and bfast. Would stay again. Love our sea view room"
john 2-night trip
Posted 18 hours ago
Algila' Ortigia Charme Hotel
Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World

10/10 Excellent
"Clean room but not all rooms have a coffee maker which seems odd otherwise great property and breakfast was amazing"
Lisa 2-night trip
Posted 4 days ago
Grand Hotel Des Ètrangers - The Leading Hotels of the World
Grand Hotel Villa Politi

Grand Hotel Villa Politi

8/10 Good
"Overall, we had a good stay at Grand Hotel Villa Politi. The hotel has a beautiful historic character and was very clean. The breakfast was excellent, with a wide variety of both continental and traditional Italian options. The swimming pool was another great highlight. Its location was very convenient for travelling by car, just outside the ZTL, with on-site parking available. However, the hotel has quite a lot of stairs, which can make getting around less convenient, and we found the staff could have been more helpful and attentive. Overall, a good option for exploring Syracuse, especially for travellers arriving by car."
Cristian 2-night trip
Posted 5 days ago
Grand Hotel Villa Politi
Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa

10/10 Excellent
"A splendid, classic property with first rate service, comfortable beds and a glorious breakfast on a breathtaking outdoor terrace. Wish we could have stayed longer."
Richard 1-night trip
Posted 12 days ago
Grand Hotel Ortigia Siracusa
Grande Albergo Alfeo

Grande Albergo Alfeo

10/10 Excellent
"We enjoyed our stay"
Anna 3-night trip
Posted 1 month ago
Grande Albergo Alfeo
Eureka Palace Hotel Spa

Eureka Palace Hotel Spa

8/10 Good
"The rooms were spacious and clean. The spa was also very good and well maintained"
IKECHUKWU 6-night trip
Posted 2 months ago
Eureka Palace Hotel Spa

Frequently asked questions

Are you searching for a great accommodation for your luxury holiday in Syracuse?
Travel to Fontanarossa Airport (CTA) Airport or Vincenzo Magliocco Airport (CIY) Airport, and then treat yourself to a stay at one of 9 Syracuse luxury hotels. While you're visiting, you might want to think about enjoying the ruins and sightseeing, which Syracuse is known for.
What's the best high-end place to stay in Syracuse?
Ortea Palace Hotel, Sicily, Autograph Collection is a luxury hotel with 2 restaurants and a full-service spa, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Grand Hotel Ortigia Siracusa and Grand Hotel Des Ètrangers - The Leading Hotels of the World are other upscale choices for your vacation.
How many luxury hotels will I be able to find in Syracuse?
Lie in the lap of luxury during your getaway to Syracuse in one of Expedia's 9 luxury hotels.
When can I expect good weather in Syracuse?
Planning for the weather is a good way to make your trip to Syracuse relaxing and enjoyable, especially when you're splurging. The hottest months are usually August and July with an average temp of 78°F, while the coldest months are February and January with an average of 56°F. Average annual precipitation for Syracuse is 26 inches.
What's there to see and do in Syracuse?
Experience all that Syracuse has to offer when you visit Temple of Apollo, Lungomare di Ortigia, and Piazza del Duomo. If you have a little extra time during your trip, you might want to check out Cathedral of Syracuse and Porto Piccolo.
How can I get around Syracuse?
It's easier to get around town in style when you know your options. To explore the surrounding area, ride one of the trains from Syracuse Station or Targia Station.

Explore a world of travel with Expedia