A coastal fortress with a stone wall and a tiled-roof building.

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Check availability on Syracuse Luxury Hotels

Tonight
Oct 6 - Oct 7
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Oct 7 - Oct 8
This weekend
Oct 9 - Oct 11
Next weekend
Oct 16 - Oct 18

Our top choices for Syracuse luxury hotels

A poolside area with lounge chairs and umbrellas, a clear blue pool, and a building with balconies.
A spacious dining area with round tables and blue chairs, large windows offering a city view, and a wooden ceiling structure.
A grand hallway with ornate columns, a tiled floor, and large potted plants.
A grand hallway with a marble floor, ornate columns, and a staircase leading to an upper level.

1. Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World
Ortigia
  • Discover the epitome of Mediterranean luxury steps from Ortigia's coastline at this spa-focused retreat with poolside indulgence.
￥98,704
￥110,346 total
includes taxes & fees
Oct 28 - Oct 29
Grand Hotel Des Ètrangers - The Leading Hotels of the World
A large, historic building with multiple floors, a prominent tower, and a waterfront marina with boats.
A grand atrium with a central column, ornate railings, and a large mural on the wall.
A balcony with a glass table and two red chairs, overlooking a coastal view with buildings and boats.
A balcony with a view of the sea and a cityscape, furnished with two chairs and a small table with a vase of flowers.

2. Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection
Ortigia
  • Mediterranean luxury awaits at this 5-star Syracuse hotel with spa, sauna, and two restaurants near Ortigia's beaches.
￥55,283
￥62,583 total
includes taxes & fees
Nov 2 - Nov 3
Ortea Palace Hotel, Sicily, Autograph Collection
A large swimming pool with a modern building in the background.
A sauna with wooden benches and a central stone pillar.
A woman relaxing in a spa bath with a modern design, including a ceiling with blue lighting and a tiled floor.
An outdoor dining area with tables and chairs, a pool, and palm trees in the background.

3. Wellness & Spa Hotel Principe di Fitalia

Wellness & Spa Hotel Principe di Fitalia
Syracuse
  • Sicilian spa escape boasts 2 outdoor pools and a serene full-service wellness center.
￥52,868
￥59,927 total
includes taxes & fees
Nov 6 - Nov 7
Wellness & Spa Hotel Principe di Fitalia
A balcony with a view of the sea, a cactus, and potted plants.
A large, multi-story building with a symmetrical facade, arched windows, and a central entrance with a colorful awning.
A poolside area with lounge chairs and umbrellas, a clear pool, and a building with multiple windows in the background.
A large, classical building with multiple windows and balconies, surrounded by a calm body of water with several yachts docked.

4. Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa
Ortigia
  • Experience luxury at grand hotel with spa services, private beach, and seaside dining in Ortigia.
￥44,729
￥50,974 total
includes taxes & fees
Nov 4 - Nov 5
Grand Hotel Ortigia Siracusa
A spa room with a large window, a hot tub, and two candles.
A spacious living room with a high ceiling, white sofas, a coffee table, and a large mirror.
A stone building with arched walkways and outdoor seating areas.
A spacious lobby with arched ceilings, a central round table with decorative items, and a modern chandelier.

5. Dimora Caiammari Luxury Hotel & Spa

Dimora Caiammari Luxury Hotel & Spa
Syracuse
  • Coastal luxury awaits at this five-star retreat offering a full-service spa, two outdoor pools, and Mediterranean dining near Fanusa Beach.
￥47,782
￥54,332 total
includes taxes & fees
Oct 25 - Oct 26
Dimora Caiammari Luxury Hotel & Spa
An aerial view of a resort with multiple swimming pools, palm trees, and a clear view of the coastline.
A pathway lined with palm trees leading to a building with a red-tiled roof.
A modern bathroom with a freestanding bathtub, a small table with toiletries, and a view of the ocean.
A modern bathroom with a freestanding bathtub, a round table with a magazine, and a view of a pool and greenery.

6. Minareto

Minareto
Syracuse
  • Syracuse seaside splendor offers indulgent relaxation with private beach access, beachfront dining, and Art Deco elegance.
￥47,240
￥53,736 total
includes taxes & fees
Nov 3 - Nov 4
Minareto
A rooftop terrace with lounge chairs, a hot tub, and a view of palm trees and buildings.
A modern hotel room with a stone wall, a staircase, a seating area with two chairs, a small table, and a desk with a phone and a lamp.
A multi-story building with a rooftop terrace featuring outdoor seating and a hot tub.
A modern hotel room with a stone accent wall, a grey sofa, a large mirror, a chandelier, and a neatly made bed with rolled towels.

7. Caportigia Boutique Hotel

Caportigia Boutique Hotel
Santa Lucia
  • Elegant Mediterranean luxury, impeccable service, and fine dining near Ortigia await at this boutique Syracuse hotel.
￥20,375
￥24,185 total
includes taxes & fees
Nov 6 - Nov 7
Caportigia Boutique Hotel
A modern kitchen with grey cabinets, a marble backsplash, and a dining area with a long table and chairs.
A covered outdoor dining area with a table and chairs, a wooden ceiling, and a view of the surrounding landscape.
A modern dining area with a table set for four, a decorative bowl centerpiece, and a view into a living area with a sofa and a window.
A bedroom with a bed, a wardrobe, a window, and a wall-mounted picture.

8. Villa Segesta holiday flat with terrace, WiFi and air conditioning

Villa Segesta holiday flat with terrace, WiFi and air conditioning
Tiche
￥95,417
￥104,300 total
includes taxes & fees
Oct 12 - Oct 13
Villa Segesta holiday flat with terrace, WiFi and air conditioning
An outdoor seating area with sofas, a table with candles, and lanterns.
A garden with a pool, lounge chairs, and a gazebo.
A dining area with stone walls, wooden beams, and tables set for dining.
A villa with a spacious patio, a well-maintained garden, and a view of the surrounding landscape.

9. Donna Coraly Country Boutique Hotel

Donna Coraly Country Boutique Hotel
Syracuse
￥43,572
￥49,706 total
includes taxes & fees
Oct 25 - Oct 26
Donna Coraly Country Boutique Hotel
A beachside restaurant with outdoor seating overlooking the sea, a clear sky, and a distant mountain range.
A room with a large window overlooking the sea, a bathtub, a table with a magazine, and a towel hanging on the wall.
A beach with clear shallow waters, a sandy shore, and a distant pier with buildings.
A woman in a red swimsuit sitting in a bathtub with a view of the ocean. There is a bottle of wine, two glasses, and a bowl of fruit on the edge of the bathtub.

10. White Bay Resort

White Bay Resort
Syracuse
￥27,497
￥32,018 total
includes taxes & fees
Oct 15 - Oct 16
White Bay Resort
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Top Syracuse Hotel Reviews

Hotel Posta

Hotel Posta

10/10 Excellent
"Super emplacement. Parking publique juste à côté. Notre chambre était petit , mais coquette et une belle vue sur la mer. Nous avons aimé. La terrasse sur le toit pour déjeuner, est super."
Katy 2-night trip
Posted 3 days ago
Hotel Posta
Grand Hotel Villa Politi

Grand Hotel Villa Politi

8/10 Good
"We overall really enjoyed our 3 night stay here, and appreciated the quiet and historic charm of this hotel. It is an incredibly unique peace of property, with an attached historic Latomie that was both beautiful and intriguing—we really wished the hotel had access to explore the areas below. We also really appreciated the continental breakfast, and were surprised by other’s complaints in reviews we had read before staying here. It was the most elaborate continental breakfast we have ever experienced, with options ranging from fresh fruit, to delicious pastries, and even eggs and bacon for those with used to a more American meal. We loved the pool as well, however we were disappointed that it was only open until 7pm every day, we would have enjoyed an evening swim. The bar was also closed, though they provided service through the bar inside. We also really enjoyed the 2 for $22 aperitivo offered from the bar. The room we stayed in was small and a bit dated, but met our expectations for an older hotel. We also had issues with the AC not turning off and making our room very cold. We were able to find parking every night, however I would not describe it as a big parking lot, and it was overflowing every night with people crammed wherever they could find room."
Rachel 3-night trip
Posted 4 days ago
Grand Hotel Villa Politi
Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel

10/10 Excellent
"Beautiful hotel with wonderful hospitality We absolutely loved our stay at Hotel Algilà Ortigia Charme. From the moment we arrived, the staff were warm, friendly and genuinely welcoming. The hotel is full of Sicilian character and charm, and its location in Ortigia was perfect for exploring on foot. Our room was comfortable and beautifully suited to the character of the hotel, and the staff were always happy to help with recommendations and anything we needed. After travelling throughout Sicily for two weeks, what stood out most was the genuine hospitality. We felt like valued guests, not just another reservation. Algilà was exactly what we hoped for from a Sicilian hotel — charming, personal and welcoming. We would happily stay here again and highly recommend it to anyone visiting Ortigia!"
Sarah 3-night trip
Posted 6 days ago
Algila' Ortigia Charme Hotel
Grande Albergo Alfeo

Grande Albergo Alfeo

10/10 Excellent
"We enjoyed our stay"
Anna 3-night trip
Posted 7 days ago
Grande Albergo Alfeo
Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection

10/10 Excellent
"El mejor de Ortigia"
William 2-night trip
Posted 3 weeks ago
Palazzo Artemide - VRetreats, SLH Collection
Eureka Palace Hotel Spa

Eureka Palace Hotel Spa

8/10 Good
"The rooms were spacious and clean. The spa was also very good and well maintained"
IKECHUKWU 6-night trip
Posted 1 month ago
Eureka Palace Hotel Spa

Frequently asked questions

Are you searching for a great accommodation for your luxury holiday in Syracuse?
Travel to Fontanarossa Airport (CTA) Airport or Vincenzo Magliocco Airport (CIY) Airport, and then treat yourself to a stay at one of 9 Syracuse luxury hotels. While you're visiting, you might want to think about enjoying the ruins and sightseeing, which Syracuse is known for.
What's the best high-end place to stay in Syracuse?
Ortea Palace Hotel, Sicily, Autograph Collection is a luxury hotel with 2 restaurants and a full-service spa, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Grand Hotel Ortigia Siracusa and Grand Hotel Des Ètrangers - The Leading Hotels of the World are other upscale choices for your vacation.
How many luxury hotels will I be able to find in Syracuse?
Lie in the lap of luxury during your getaway to Syracuse in one of Expedia's 9 luxury hotels.
When can I expect good weather in Syracuse?
Planning for the weather is a good way to make your trip to Syracuse relaxing and enjoyable, especially when you're splurging. The hottest months are usually August and July with an average temp of 78°F, while the coldest months are February and January with an average of 56°F. Average annual precipitation for Syracuse is 26 inches.
What's there to see and do in Syracuse?
Experience all that Syracuse has to offer when you visit Temple of Apollo, Lungomare di Ortigia, and Piazza del Duomo. If you have a little extra time during your trip, you might want to check out Cathedral of Syracuse and Porto Piccolo.
How can I get around Syracuse?
It's easier to get around town in style when you know your options. To explore the surrounding area, ride one of the trains from Syracuse Station or Targia Station.

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