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Find hotels in Medical Center District, San Antonio from ￥13,086

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Tonight
May 13 - May 14
Tomorrow
May 14 - May 15
This weekend
May 17 - May 19
Next weekend
May 24 - May 26

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Discover 4,352 Medical Center District hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Indoor pool
Drury Inn & Suites Near La Cantera Parkway
3.0 star property
9.4 out of 10, Exceptional, (1008)
"This place is great. I love the kickbacks. Free parking, 3 free drinks, free wifi, free popcorn, free food, and free breakfast! It's a great family hotel. The hotel was so good I didn't mind the construction near by. You can walk to the Applebee's it's so close. Pool was okay and the outside terrace was a nice place to enjoy my free wine. I will go back over and over again. "
The price is ￥15,421
￥18,228 total
includes taxes & fees
May 20 - May 21
Drury Inn & Suites Near La Cantera Parkway
Lobby
Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
9.4 out of 10, Exceptional, (1079)
"very nice, with great location"
The price is ￥14,019
￥16,571 total
includes taxes & fees
May 20 - May 21
Drury Inn & Suites San Antonio Northwest Medical Center
Exterior
Omni La Mansion del Rio
4.0 star property
9.2 out of 10, Wonderful, (2133)
"Location"
The price is ￥29,340
￥35,202 total
includes taxes & fees
Jun 5 - Jun 6
Omni La Mansion del Rio
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Terrace/patio
Canopy by Hilton San Antonio Riverwalk
4.0 star property
9.2 out of 10, Wonderful, (1262)
"the location of the hotel"
The price is ￥29,793
￥35,843 total
includes taxes & fees
May 19 - May 20
Canopy by Hilton San Antonio Riverwalk
Pillowtop beds, in-room safe, blackout drapes, iron/ironing board
Spark By Hilton San Antonio Northwest near Six Flags
3.0 star property
9.0 out of 10, Wonderful, (30)
"I will definitely stay here again. My room was clean, the staff was very kind, the air conditioner was great, and the location was perfect for my needs. (close to UTSA/shopping/restaurants)"
The price is ￥14,477
￥17,113 total
includes taxes & fees
May 20 - May 21
Spark By Hilton San Antonio Northwest near Six Flags
Lobby
Tru By Hilton San Antonio At The Rim, Tx
2.5 star property
9.0 out of 10, Wonderful, (512)
"Excellent hotel and great location "
The price is ￥15,757
￥18,626 total
includes taxes & fees
May 27 - May 28
Tru By Hilton San Antonio At The Rim, Tx
Outdoor pool, a heated pool, open 8:00 AM to 10:00 PM, free cabanas
Hotel Contessa
4.0 star property
8.8 out of 10, Excellent, (2745)
"Amazing service and accommodations! "
The price is ￥25,922
￥32,928 total
includes taxes & fees
May 21 - May 22
Hotel Contessa
Miscellaneous
Grand Hyatt San Antonio River Walk
4.0 star property
8.8 out of 10, Excellent, (1060)
"Close to the Riverwalk and very nice and clean"
The price is ￥29,474
￥35,308 total
includes taxes & fees
May 26 - May 27
Grand Hyatt San Antonio River Walk
3 outdoor pools, cabanas (surcharge), sun loungers
Hyatt Regency Hill Country Resort & Spa
4.0 star property
8.8 out of 10, Excellent, (1004)
"Great service; hotel is pretty; but a little inconvenience about repairing "
The price is ￥43,618
￥59,214 total
includes taxes & fees
May 19 - May 20
Hyatt Regency Hill Country Resort & Spa
4 outdoor pools, cabanas (surcharge), pool umbrellas
JW Marriott San Antonio Hill Country Resort & Spa
4.5 star property
8.8 out of 10, Excellent, (1004)
"Staff was extremely helpful and friendly. Food in restaurants was delicious. "
The price is ￥55,925
￥74,016 total
includes taxes & fees
May 27 - May 28
JW Marriott San Antonio Hill Country Resort & Spa
Exterior
San Antonio Marriott Rivercenter on the River Walk
4.0 star property
8.8 out of 10, Excellent, (1002)
"Was nice that everything is a short walking distance to all the attractions "
The price is ￥25,688
￥34,505 total
includes taxes & fees
May 26 - May 27
San Antonio Marriott Rivercenter on the River Walk
Lobby
Aloft San Antonio UTSA Area
3.0 star property
8.8 out of 10, Excellent, (545)
"Very nice property "
The price is ￥13,086
￥15,469 total
includes taxes & fees
May 19 - May 20
Aloft San Antonio UTSA Area
Front of property
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
2.5 star property
8.6 out of 10, Excellent, (2992)
"Everything was good, I don’t have any complaint "
The price is ￥14,830
￥17,530 total
includes taxes & fees
May 19 - May 20
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
Restaurant
Element San Antonio Riverwalk
4.0 star property
8.6 out of 10, Excellent, (236)
"Simple design and very clean!"
The price is ￥17,759
￥20,992 total
includes taxes & fees
May 19 - May 20
Element San Antonio Riverwalk
Outdoor pool, sun loungers
Home2 Suites by Hilton San Antonio Riverwalk, TX
3.0 star property
8.6 out of 10, Excellent, (1002)
"Nice room."
The price is ￥19,730
￥23,035 total
includes taxes & fees
May 27 - May 28
Home2 Suites by Hilton San Antonio Riverwalk, TX
Indoor pool, outdoor pool, open 6 AM to 10 PM, pool umbrellas
Holiday Inn San Antonio Seaworld, an IHG Hotel
3.0 star property
8.6 out of 10, Excellent, (1002)
"Front desk clerk Anthony was friendly and helpful "
The price is ￥16,679
￥19,716 total
includes taxes & fees
May 19 - May 20
Holiday Inn San Antonio Seaworld, an IHG Hotel
Pool
Sonesta ES Suites San Antonio Downtown Alamo Plaza
3.0 star property
8.4 out of 10, Very Good, (1320)
"The property is a bit dated but good value for money overall. There is no daily cleaning service so you need to book this in advance. The staff are very friendly and helpful and the daily parking rate is pretty standard for downtown San Antonio"
The price is ￥16,279
￥19,244 total
includes taxes & fees
Jun 2 - Jun 3
Sonesta ES Suites San Antonio Downtown Alamo Plaza
Meeting facility
Holiday Inn San Antonio - Riverwalk, an IHG Hotel
3.0 star property
8.4 out of 10, Very Good, (1478)
"Everyone at the front desk was helpful and provided great customer service. "
The price is ￥19,488
￥23,036 total
includes taxes & fees
May 26 - May 27
Holiday Inn San Antonio - Riverwalk, an IHG Hotel
Terrace/patio
AC Hotel by Marriott San Antonio Riverwalk
4.0 star property
8.4 out of 10, Very Good, (224)
"Room very clean, great location "
The price is ￥19,005
￥22,465 total
includes taxes & fees
May 19 - May 20
AC Hotel by Marriott San Antonio Riverwalk
Exterior
Sonesta ES Suites San Antonio Northwest - Medical Center
3.0 star property
8.4 out of 10, Very Good, (1005)
"Good enough for a quick stay but its still a regular motel feel. Breakfast was good though!"
The price is ￥14,947
￥17,668 total
includes taxes & fees
May 19 - May 20
Sonesta ES Suites San Antonio Northwest - Medical Center
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Medical Center District

Hotels in top San Antonio neighborhoods Learn more about Medical Center District
Downtown - Riverwalk which includes heritage architecture, boating and a river or creek

Downtown San Antonio

3 out of top 10 points of interest in this area
4/5(9,525 area reviews)

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

Find hotels in Downtown San Antonio

Medical Center District hotels information

Number of reviews
22,480
Accommodation
4,352 hotels
Lowest Price
￥13,086
Highest Price
￥55,925

Frequently asked questions

What is Medical Center District like?

Travelers are sure to enjoy a stay in San Antonio's Medical Center District neighborhood. Are you looking for Medical Center District travel tips? Be sure to check out USAA Corporate Office Headquarters and The San Antonio Art Institute while you're in the neighborhood.

What's a favorite place to stay in Medical Center District?

Based on Expedia customer reviews, Fairfield Inn & Suites by Marriott San Antonio Medical Center is the highest ranked property in Medical Center District. This hotel offers free breakfast and free parking. Other favorite options in the area include Atria Inn & Suites and Courtyard by Marriott Medical Center San Antonio.

How many hotels will I be able to find in Medical Center District?

Expedia has 127 hotels and other accommodations in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.

If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?

Yes! You'll find that most hotel bookings are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view top deals in Medical Center District.

Where can I learn more about changing or cancelling my trip to Medical Center District?

For more information about changing or cancelling your trip to Medical Center District, go to https://www.expedia.com/service/.

What can I see and do in this San Antonio neighborhood?

A few attractions you might want to check out while you're in Medical Center District are USAA Corporate Office Headquarters and The San Antonio Art Institute. Wonderland of the Americas Mall and First Unitarian Universalist Church are also worth a visit when you're out sightseeing in San Antonio.

Recent reviews of Medical Center District hotels

Hotel Valencia Riverwalk

Hotel Valencia Riverwalk

5/5 Excellent
Valencia
"great place to stay ..... "
A verified traveler stayed at Hotel Valencia Riverwalk
Posted 13 hours ago
Hotel Valencia Riverwalk