Medical Center District Vacations from ￥359,726

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The Latest Medical Center District Vacation Packages

Price found within the past 48 hours. Click for updated prices.
The Continental, powered by Placemakr - Downtown - Market Square

The Continental, powered by Placemakr - Downtown - Market Square

3.5 out of 5
Downtown San Antonio
Price was ￥408,844, price is now ￥359,726 per person
￥359,726
per person
Jun 14 - Jun 20
found 1 day ago
Roundtrip non-stop flight included
Tokyo (HND) to San Antonio (SAT)
9.6/10 Exceptional! (84 reviews)
Parking is a bit frustrating, but cheaper than other places

Reviewed on Mar 27, 2026

Hyatt Regency Hill Country Resort and Villas

Hyatt Regency Hill Country Resort and Villas

4 out of 5
Far West Side
Price was ￥577,361, price is now ￥479,454 per person
￥479,454
per person
Jun 14 - Jun 20
found 1 day ago
Roundtrip non-stop flight included
Tokyo (HND) to San Antonio (SAT)
8.8/10 Excellent! (1,003 reviews)
Everything was amazing!

Reviewed on Mar 30, 2026

Thompson San Antonio - Riverwalk, by Hyatt

Thompson San Antonio - Riverwalk, by Hyatt

5 out of 5
Downtown San Antonio
Price was ￥497,252, price is now ￥437,360 per person
￥437,360
per person
Jun 14 - Jun 20
found 1 day ago
Roundtrip non-stop flight included
Tokyo (HND) to San Antonio (SAT)
9/10 Wonderful! (965 reviews)
The Thompson was excellent all around. The staff was especially helpful and the valet service was a huge plus given the lack of available parking in the area. Highly recommended.

Reviewed on Mar 19, 2026

Plaza San Antonio Hotel & Spa, Autograph Collection

Plaza San Antonio Hotel & Spa, Autograph Collection

4 out of 5
Downtown San Antonio
Price was ￥468,591, price is now ￥413,712 per person
￥413,712
per person
Jun 14 - Jun 20
found 1 day ago
Roundtrip non-stop flight included
Tokyo (HND) to San Antonio (SAT)
9.4/10 Exceptional! (742 reviews)
A+++ staff. Great pool area. Oasis in the city. Accessible room. Only con - No grab bars in shower or lav. Overall very pleased.

Reviewed on Mar 29, 2026

Kimpton Santo San Antonio - Riverwalk by IHG

Kimpton Santo San Antonio - Riverwalk by IHG

4.5 out of 5
Downtown San Antonio
Price was ￥465,160, price is now ￥414,634 per person
￥414,634
per person
Jun 14 - Jun 20
found 1 day ago
Roundtrip non-stop flight included
Tokyo (HND) to San Antonio (SAT)
9.4/10 Exceptional! (772 reviews)
I stayed here with my son for Monster Jam. The hotel was very conveniently located for a short walk to the Alamodome. The nightly happy hour was a nice touch. The overnight front desk agent gave my son a cowboy hat at check out, which he absolutely loved. Thanks for a great stay!

Reviewed on Mar 30, 2026

Where to stay in Medical Center District

Find the best Medical Center District areas and neighborhoods for the activities you enjoy most. Learn more about Medical Center District
Downtown San Antonio

Downtown San Antonio

4 out of top 10 points of interest in this area
4/5(9,632 area reviews)

Explore the heart of San Antonio with top attractions like the Alamo and River Walk, or enjoy kayaking and bicycling to the World Heritage Missions. Discover historic sites, theaters, and shopping at Rivercenter, all easily accessible by public transit.

Find hotels in Downtown San Antonio

Medical Center District Hotel Deals

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd San Antonio TX
Fully refundableReserve now, pay when you stay
The price is ￥13,104 per night from May 1 to May 2
￥13,104
￥15,488 total
May 1 - May 2
includes taxes & fees
8.4/10 Very Good! (3,245 reviews)
The front desk staff need improvement, they are not friendly at all and when you ask for something they answer in a terrible mood

Reviewed on Mar 31, 2026

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410 San Antonio TX
Fully refundableReserve now, pay when you stay
The price is ￥17,169 per night from Apr 16 to Apr 17
￥17,169
￥20,402 total
Apr 16 - Apr 17
includes taxes & fees
8.6/10 Excellent! (1,009 reviews)
The safe batteries were completely dead. The cleaning people did not fully stock the toilet paper, or cups. Things that should be automatic. The check in staff were great, especially the midnight crew.

Reviewed on Mar 31, 2026

San Antonio Marriott Northwest Medical Center
Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

3 out of 5
8585 Marriott Dr San Antonio TX
Fully refundableReserve now, pay when you stay
The price is ￥15,661 per night from Apr 9 to Apr 10
￥15,661
￥18,512 total
Apr 9 - Apr 10
includes taxes & fees
8.8/10 Excellent! (1,003 reviews)
The staff is knowledgeable ,friendly and professional

Reviewed on Mar 24, 2026

Courtyard by Marriott Medical Center San Antonio
See all 4,735 properties in Medical Center District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Medical Center District vacation package cost?
Starting from just ￥359,726, a vacation package is your passport to low-priced travel. Create your own Medical Center District adventure by picking from our huge range of airfares, hotels and rental cars.
How do I get a cheap travel package to Medical Center District?
It's as simple as bundling. Hotels, rental cars and flights — combine whatever you need into a Medical Center District vacation package and save. Score even better deals when you include extras such as activities or tours to your booking. But that's not the only good part. You have the freedom to customize your vacation your own way. We offer over 550 airlines and 1,000,000 properties throughout the world, so that everyone has a chance to travel and fulfill those vacation dreams.
Where should I stay in Medical Center District?
Make a reservation just around the corner from Six Flags Fiesta Texas, one of this area's most well-known attractions. It's the ideal spot for serious sightseers.
What are the top hotels in Medical Center District?
Amazing, Contemporary, Beautiful and Fairfield Inn & Suites by Marriott San Antonio Medical Center are two of the most well-known hotels in Medical Center District. Why not take a look at the amenities and rates at each and then make up your mind?
How far in advance should I book my Medical Center District vacation?
It all depends on the airline, but it's usually possible to look up international fares on Expedia up to 12 months in advance. While it's generally recommended to book ahead of time, lucky customers will sometimes nab a cheaper ticket just weeks before the date of departure.
What does an Expedia Medical Center District travel package include?
Flights, car rentals and hotels — we connect you to the very best deals. All you'll have to do is figure out your ideal combination. Once you've made your booking, you can add on the fun stuff like activities and sightseeing tours. Our travel packages make it easy to customize an exciting Medical Center District vacation.
What should I know before booking a Medical Center District travel package?
You'll save plenty with an Expedia travel package. Combine your airfares, rental cars and hotels and land fantastic discounts. You're not limited to hotels, however. Book with us and select from island resorts, city apartments and just about everything in between!
Can I choose my airline with a Medical Center District Expedia vacation package?
Yes, you're in charge. We have access to over 550 partner airlines globally, so you can tailor your Medical Center District trip according to your budget and travel needs.
If I'm not able to travel, can I cancel my Medical Center District vacation package?
Whether it's your hotel or flight, you can cancel or change it. Booked your Medical Center District vacation package in the last 24 hours? You may be able to make any changes for free. For bookings made more than 24 hours ago, you may be charged a fee by your airline, hotel or car rental company. For more information, head to our Customer Service Portal. We're here to help you every step of the way.

Discover the most popular places to visit in Medical Center District

SanAntonio_SouthTexasMedicalCenter_6193120_01

South Texas Medical Center

4/5(36 reviews)

Though South Texas Medical Center might be what brings you to town, perhaps you'll have a chance to explore more of San Antonio while you are here.

South Texas Medical Center

University of Texas Health and Science Center at San Antonio

4/5(29 reviews)

Though University of Texas Health and Science Center at San Antonio might be what brings you to town, perhaps you'll have a chance to explore more of San Antonio while you are here.

University of Texas Health and Science Center at San Antonio

Things to do

SEA LIFE San Antonio

SEA LIFE San Antonio

￥4,051
per adult
78% of travellers recommend
SEA LIFE San Antonio
San Antonio Zoo Any Day Ticket including ZooLights

San Antonio Zoo Any Day Ticket

￥4,613
per adult
96% of travellers recommend
San Antonio Zoo Any Day Ticket
San Antonio Old Town Trolley Hop-on Hop-Off Tour

San Antonio Old Town Trolley Hop-on Hop-Off Tour

￥8,430
per adult
92% of travellers recommend
San Antonio Old Town Trolley Hop-on Hop-Off Tour
See all activities in San Antonio
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.