Medical Center District Vacations from ￥227,135

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The Latest Medical Center District Vacation Packages

Price found within the past 48 hours. Click for updated prices.
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
Medical Center District
Price was ￥255,942, price is now ￥227,135 per person
￥227,135
per person
Jan 18 - Jan 23
found 8 hours ago
Roundtrip non-stop flight included
Tokyo (TYO) to San Antonio (SAT)
8.6/10 Excellent! (3,018 reviews)
The breakfast food was always replenished, and there was plenty of it. The staff was friendly and very professional. The room was comfortable. It had a microwave and minifridge. The only issue i had with the room was the hot water. It took so long to get warm. Overall, it was a pleasant stay. Easy access to the highway. Close to the airport.

Reviewed on Nov 5, 2025

Thompson San Antonio - Riverwalk, by Hyatt

Thompson San Antonio - Riverwalk, by Hyatt

5 out of 5
Downtown San Antonio
Price was ￥329,210, price is now ￥282,480 per person
￥282,480
per person
Jan 18 - Jan 23
found 8 hours ago
Roundtrip non-stop flight included
Tokyo (TYO) to San Antonio (SAT)
9/10 Wonderful! (866 reviews)
This property is nice. I would pick a location nearer to the Alamo.

Reviewed on Nov 6, 2025

Kimpton Santo San Antonio - Riverwalk by IHG

Kimpton Santo San Antonio - Riverwalk by IHG

4.5 out of 5
Downtown San Antonio
Price was ￥299,026, price is now ￥262,857 per person
￥262,857
per person
Jan 18 - Jan 23
found 8 hours ago
Roundtrip non-stop flight included
Tokyo (TYO) to San Antonio (SAT)
9.4/10 Exceptional! (552 reviews)
Most friendly staff. Also we loved the free wine at night!

Reviewed on Nov 3, 2025

Hotel Gibbs Downtown Riverwalk

Hotel Gibbs Downtown Riverwalk

2 out of 5
Downtown San Antonio
Price was ￥350,010, price is now ￥312,552 per person
￥312,552
per person
Jan 18 - Jan 23
found 8 hours ago
Roundtrip non-stop flight included
Tokyo (TYO) to San Antonio (SAT)
9/10 Wonderful! (1,786 reviews)
Upon arrival we really liked the obvious history the building had and the architecture that was preserved was cool! But when we got up to the room I noticed a spill on the carpet in which we called them up to clean and it took them only but 5 minutes, which means the room was not properly looked over and cleaned before. There was mold along the grout on the shower floor, and the water pressure was terrible! Basically a trickle lol but breakfast was good and the staff was very friendly it just felt like a lot was missed tbh

Reviewed on Nov 6, 2025

Hotel Contessa

Hotel Contessa

4 out of 5
Downtown San Antonio
Price was ￥351,536, price is now ￥315,177 per person
￥315,177
per person
Dec 9 - Dec 11
found 13 hours ago
Roundtrip non-stop flight included
Tokyo (TYO) to San Antonio (SAT)
9/10 Wonderful! (3,330 reviews)
Great food and the mariachi band was incredible! Very convenient location.

Reviewed on Nov 5, 2025

Where to stay in Medical Center District

Find the best Medical Center District areas and neighborhoods for the activities you enjoy most. Learn more about Medical Center District
Downtown - Riverwalk which includes heritage architecture, boating and a river or creek

Downtown San Antonio

4 out of top 10 points of interest in this area
4/5(9,525 area reviews)

Explore the heart of San Antonio with top attractions like the Alamo and River Walk, or enjoy kayaking and bicycling to the World Heritage Missions. Discover historic sites, theaters, and shopping at Rivercenter, all easily accessible by public transit.

Find hotels in Downtown San Antonio

Medical Center District Hotel Deals

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is ￥13,582 per night from Nov 9 to Nov 10
￥13,582
￥16,054 total
Nov 9 - Nov 10
includes taxes & fees
8.4/10 Very Good! (3,037 reviews)
Yes all

Reviewed on Nov 6, 2025

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is ￥13,613 per night from Nov 14 to Nov 15
￥13,613
￥16,178 total
Nov 14 - Nov 15
includes taxes & fees
8.6/10 Excellent! (1,025 reviews)
Yes

Reviewed on Nov 1, 2025

San Antonio Marriott Northwest Medical Center
Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center

2.5 out of 5
7203 Wurzbach Road, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is ￥12,236 per night from Nov 17 to Nov 18
￥12,236
￥14,285 total
Nov 17 - Nov 18
includes taxes & fees
9/10 Wonderful! (1,029 reviews)
Staff was helpful! Everything super clean and free breakfast was good

Reviewed on Nov 2, 2025

Fairfield Inn & Suites by Marriott San Antonio Medical Center
See all 4,617 properties in Medical Center District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Medical Center District vacation package cost?
Starting from just ￥227,135, a vacation package is your passport to low-priced travel. Create your own Medical Center District adventure by picking from our huge range of airfares, hotels and rental cars.
How do I get a cheap travel package to Medical Center District?
It's as simple as bundling. Hotels, rental cars and flights — combine whatever you need into a Medical Center District vacation package and save. Score even better deals when you include extras such as activities or tours to your booking. But that's not the only good part. You have the freedom to customize your vacation your own way. We offer over 550 airlines and 1,000,000 properties throughout the world, so that everyone has a chance to travel and fulfill those vacation dreams.
Where should I stay in Medical Center District?
Make a reservation just around the corner from Six Flags Fiesta Texas, one of this area's most well-known attractions. It's the ideal spot for serious sightseers.
What are the top hotels in Medical Center District?
Amazing, Contemporary, Beautiful and Fairfield Inn & Suites by Marriott San Antonio Medical Center are two of the most well-known hotels in Medical Center District. Why not take a look at the amenities and rates at each and then make up your mind?
How far in advance should I book my Medical Center District vacation?
It all depends on the airline, but it's usually possible to look up international fares on Expedia up to 12 months in advance. While it's generally recommended to book ahead of time, lucky customers will sometimes nab a cheaper ticket just weeks before the date of departure.
What does an Expedia Medical Center District travel package include?
Flights, car rentals and hotels — we connect you to the very best deals. All you'll have to do is figure out your ideal combination. Once you've made your booking, you can add on the fun stuff like activities and sightseeing tours. Our travel packages make it easy to customize an exciting Medical Center District vacation.
What should I know before booking a Medical Center District travel package?
You'll save plenty with an Expedia travel package. Combine your airfares, rental cars and hotels and land fantastic discounts. You're not limited to hotels, however. Book with us and select from island resorts, city apartments and just about everything in between!
Can I choose my airline with a Medical Center District Expedia vacation package?
Yes, you're in charge. We have access to over 550 partner airlines globally, so you can tailor your Medical Center District trip according to your budget and travel needs.
If I'm not able to travel, can I cancel my Medical Center District vacation package?
Whether it's your hotel or flight, you can cancel or change it. Booked your Medical Center District vacation package in the last 24 hours? You may be able to make any changes for free. For bookings made more than 24 hours ago, you may be charged a fee by your airline, hotel or car rental company. For more information, head to our Customer Service Portal. We're here to help you every step of the way.

Discover the most popular places to visit in Medical Center District

South Texas Medical Center

Though South Texas Medical Center might be what brings you to town, perhaps you'll have a chance to explore more of San Antonio while you are here.

South Texas Medical Center

University of Texas Health and Science Center at San Antonio

Though University of Texas Health and Science Center at San Antonio might be what brings you to town, perhaps you'll have a chance to explore more of San Antonio while you are here.

University of Texas Health and Science Center at San Antonio

Things to do

SEA LIFE San Antonio

SEA LIFE San Antonio

￥3,592
per adult
78% of travellers recommend
SEA LIFE San Antonio
San Antonio: San Antonio Zoo Any Day Ticket

San Antonio: San Antonio Zoo Any Day Ticket

￥4,517
per adult
94% of travellers recommend
San Antonio: San Antonio Zoo Any Day Ticket
San Antonio Old Town Trolley Hop-on Hop-Off Tour

San Antonio Old Town Trolley Hop-on Hop-Off Tour

￥7,886
per adult
96% of travellers recommend
San Antonio Old Town Trolley Hop-on Hop-Off Tour
See all activities in San Antonio
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.