Medical Center District, TX

San Antonio

River walk in San Antonio
Riverboat on the San Antonio River Walk, San Antonio, Texas, United States of America.
River walk in San Antonio
SanAntonio_SouthTexasMedicalCenter_6193120_01

Popular places to visit

Things to do


Medical Center District Hotel Deals

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd San Antonio TX
The price is ¥13,092 per night from Apr 23 to Apr 24
¥13,092
¥15,476 total
Apr 23 - Apr 24
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (3,244 reviews)
Charged a $10 parking fee which was not mentioned up front. Expedia jacked up the price which me to call the hotel directly to get the original price. I will not use Expedia again.

Reviewed on Apr 4, 2026

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410 San Antonio TX
The price is ¥14,882 per night from May 1 to May 2
¥14,882
¥17,684 total
May 1 - May 2
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy a free area shuttle, room service, and a 24-hour fitness center. Our guests praise the helpful ...
8.6/10 Excellent! (1,006 reviews)
Room was clean the bed & pillows felt amazing

Reviewed on Apr 4, 2026

San Antonio Marriott Northwest Medical Center
Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

3 out of 5
8585 Marriott Dr San Antonio TX
The price is ¥15,648 per night from Apr 12 to Apr 13
¥15,648
¥18,498 total
Apr 12 - Apr 13
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,002 reviews)
The staff was excellent in the front and they approved my reservation on Expedia to be canceled as I needed. I had reserved a week out and I needed the room the moment I was there in the front. The manager booked the reservation for me that night and I had somewhere to stay without getting double ...

Reviewed on Apr 2, 2026

Courtyard by Marriott Medical Center San Antonio
Sonesta ES Suites San Antonio Downtown Alamo Plaza

Sonesta ES Suites San Antonio Downtown Alamo Plaza

3 out of 5
425 Bonham San Antonio TX
The price is ¥16,151 per night from Apr 6 to Apr 7
¥16,151
¥19,091 total
Apr 6 - Apr 7
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (2,082 reviews)
Breakfast was fine. Did not like the $35.00 parking fee

Reviewed on Apr 4, 2026

Sonesta ES Suites San Antonio Downtown Alamo Plaza
Riverwalk Plaza

Riverwalk Plaza

4 out of 5
100 Villita Street San Antonio TX
The price is ¥14,226 per night from Apr 12 to Apr 13
¥14,226
¥16,817 total
Apr 12 - Apr 13
includes taxes & fees
Book a stay at this family-friendly hotel in San Antonio. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the restaurant and the ...
8/10 Very Good! (6,416 reviews)
Ok property. Out of date and the "river view" is more like a drainage ditch, but still ok

Reviewed on Apr 4, 2026

Riverwalk Plaza
Crockett Hotel

Crockett Hotel

3 out of 5
320 Bonham San Antonio TX
The price is ¥16,645 per night from May 3 to May 4
¥16,645
¥19,677 total
May 3 - May 4
includes taxes & fees
Book a stay at this historic hotel in San Antonio. Enjoy free WiFi, valet parking (surcharge), and a 24-hour front desk. Our guests praise the pool and the restaurant ...
8.8/10 Excellent! (2,623 reviews)
Loved the restaurant food and drinks, easy to walk to places

Reviewed on Apr 3, 2026

Crockett Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Medical Center District

SanAntonio_UniversityofTexasSanAntonio_502634_03

Northwest Side

While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Dub Farris Athletic Complex.

Northwest Side
River Walk in San Antonio, Texas

Midtown

3.5/5(201 area reviews)

Unique features of Midtown include the river views and bars. Make a stop by San Antonio Zoo and Aquarium or The DoSeum while you're exploring the area.

Midtown
Historic architecture Spanish San Antonio Texas Mission San Jose on a cloudy day

La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

La Cantera District
Tobin Hill

Tobin Hill

Though Tobin Hill might not have many top sights, you can venture to the surrounding area to see attractions like Alamo and San Antonio Zoo and Aquarium.

Tobin Hill
Dallas Skyline Reflection on Trinity River During Sunset, Dallas, Texas.

Uptown

While visiting Uptown, you might make a stop by sights like San Antonio Zoo and Aquarium and Marion Koogler McNay Art Museum.

Uptown
SanAntonio_AlamoHeights_553248633938969296_04

Alamo Heights

You'll enjoy the museums and coffeehouses in Alamo Heights. You might want to make time for a stop at San Antonio River or Toilet Seat Museum.

Alamo Heights


Medical Center District, TX

Explore a world of travel with Expedia