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Our top choices for Historic Southwest hotels

Lunch and dinner served, American cuisine
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
3.0 star property
Historic Southwest
8.6 out of 10, Excellent, (1004)
"the breakfast and the friendly check-in staff"
United States
Ella
The price is ￥21,407
￥24,644 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Exterior
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 star property
Historic Southwest
8.8 out of 10, Excellent, (894)
"Room was clean and comfortable Staff courteous Comfortable beds Great restaurant"
United States
Matney
The price is ￥12,510
￥14,403 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Breakfast served
Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN
3.0 star property
Historic Southwest
8.8 out of 10, Excellent, (856)
"Yes the workers are amazing "
United States
Luciana
The price is ￥16,693
￥19,218 total
includes taxes & fees
Jan 30 - Jan 31, 2026
Hilton Garden Inn Rochester Downtown, MN
Courtyard
EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG
4.0 star property
Kutzky Park, 0.8 km from Historic Southwest
9.4 out of 10, Exceptional, (971)
"The staff was very friendly and the room spotless. "
United States
Judith
The price is ￥17,827
￥20,837 total
includes taxes & fees
Jan 2 - Jan 3, 2026
EVEN Hotel Rochester - Mayo Clinic Area by IHG
Exterior
Holiday Inn Express Rochester South - Mayo Area by IHG

Holiday Inn Express Rochester South - Mayo Area by IHG

Holiday Inn Express Rochester South - Mayo Area by IHG
2.5 star property
6.2 km from Historic Southwest
8.8 out of 10, Excellent, (1001)
"Clean room, clean hotel, friendly staff Would stay here again."
United States
Chee
The price is ￥11,416
￥13,144 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Holiday Inn Express Rochester South - Mayo Area by IHG
Exterior
Hampton Inn & Suites Rochester-North

Hampton Inn & Suites Rochester-North

Hampton Inn & Suites Rochester-North
2.5 star property
8.1 km from Historic Southwest
9.2 out of 10, Wonderful, (1000)
"Love room, breakfast, and shuttle to Mayo. We always stay there"
United States
Laureen
The price is ￥13,941
￥16,048 total
includes taxes & fees
Jan 25 - Jan 26, 2026
Hampton Inn & Suites Rochester-North
Front of property
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3.0 star property
6.4 km from Historic Southwest
7.2 out of 10, Good, (1028)
"Staff was courteous and breakfast was well stocked."
United States
Doug
The price is ￥10,556
￥12,153 total
includes taxes & fees
Jan 3 - Jan 4, 2026
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Room, 2 Queen Beds | Desk, blackout drapes, iron/ironing board, free cribs/infant beds
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area
3.5 star property
Downtown Rochester, 1 km from Historic Southwest
8.0 out of 10, Very Good, (1525)
"Clean room, good room service and good breakfast."
United States
Donald
The price is ￥20,016
￥23,043 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Kahler Inn and Suites - Mayo Clinic Area
Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room) | Blackout drapes, soundproofing, iron/ironing board, rollaway beds
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 star property
1.9 km from Historic Southwest
8.2 out of 10, Very Good, (798)
"This hotel was"
United States
Sheila
The price is ￥14,669
￥16,888 total
includes taxes & fees
Jan 26 - Jan 27, 2026
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Front of property - evening/night
Kahler Grand Hotel

Kahler Grand Hotel

Kahler Grand Hotel
3.0 star property
Downtown Rochester, 1 km from Historic Southwest
8.4 out of 10, Very Good, (1847)
"Room was clean staff was excellent! "
United States
Helen
The price is ￥19,391
￥22,324 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Kahler Grand Hotel
Terrace/patio
Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area
3.0 star property
1.8 km from Historic Southwest
9.6 out of 10, Exceptional, (888)
"Great stay,clean and friendly"
United States
Janet
The price is ￥18,559
￥21,367 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Home2 Suites by Hilton Rochester Mayo Clinic Area
Exterior
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
3.0 star property
Kutzky Park, 1.1 km from Historic Southwest
9.2 out of 10, Wonderful, (773)
"Clean room and housekeeping service was excellent"
United States
Dawn
The price is ￥13,918
￥16,023 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Indoor spa tub
Quality Inn near Medical Center

Quality Inn near Medical Center

Quality Inn near Medical Center
2.5 star property
7.9 km from Historic Southwest
7.8 out of 10, Good, (814)
"Food was good. Staff was great then you go to know them. "
United States
Kayle
The price is ￥9,148
￥10,531 total
includes taxes & fees
Jan 23 - Jan 24, 2026
Quality Inn near Medical Center
Exterior
Spark by Hilton Rochester South

Spark by Hilton Rochester South

Spark by Hilton Rochester South
3.0 star property
6.2 km from Historic Southwest
9.4 out of 10, Exceptional, (333)
"Very good accommodations at a wonderful price. "
United States
David
The price is ￥11,028
￥12,696 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Spark by Hilton Rochester South
Exterior
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
2.5 star property
Kutzky Park, 1.3 km from Historic Southwest
8.8 out of 10, Excellent, (766)
"Clean room, friendly staff. The only minus is the lighting in the bathroom, way too dim. "
United States
Stacy
The price is ￥17,045
￥19,623 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
Exterior
Aspen Select

Aspen Select

Aspen Select
3.5 star property
1 km from Historic Southwest
8.4 out of 10, Very Good, (1002)
"I had a wonderful stay at Aspen Select. "
United States
Nehra
Aspen Select
Property entrance
Country Inn & Suites Rochester South Mayo Clinic

Country Inn & Suites Rochester South Mayo Clinic

Country Inn & Suites Rochester South Mayo Clinic
3.0 star property
4.9 km from Historic Southwest
8.4 out of 10, Very Good, (1002)
"Very friendly staff; clean, comfortable room. "
United States
Colleen
The price is ￥14,489
￥16,679 total
includes taxes & fees
Jan 21 - Jan 22, 2026
Country Inn & Suites Rochester South Mayo Clinic
Desk, iron/ironing board, free WiFi, bed sheets
Brentwood Inn & Suites

Brentwood Inn & Suites

Brentwood Inn & Suites
2.5 star property
Downtown Rochester, 1 km from Historic Southwest
8.8 out of 10, Excellent, (1003)
"Convenient, clean location and friendly staff"
United States
Kaushika
The price is ￥17,593
￥20,253 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Brentwood Inn & Suites
Serves lunch, dinner, and happy hour
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic
3.0 star property
2 km from Historic Southwest
8.2 out of 10, Very Good, (1154)
"Check in was fast, room, and pool area were great, its connected to the crooked pint, making dining convenient. "
United States
Brian
The price is ￥11,669
￥13,434 total
includes taxes & fees
Jan 3 - Jan 4, 2026
AmericInn by Wyndham Rochester Near Mayo Clinic
Front of property
Aspen Suites

Aspen Suites

Aspen Suites
3.0 star property
0.9 km from Historic Southwest
9.0 out of 10, Wonderful, (697)
"Room was clean and inviting and staff always willing to help"
United States
Maria del Carmen
Aspen Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Historic Southwest

Find the best Historic Southwest areas and neighborhoods for the activities you enjoy most.
Rochester showing skyline and a city
Photo by Howard Lower Photography
Open Photo by Howard Lower Photography

Downtown Rochester

If you're spending some time in Downtown Rochester, Mayo Civic Center and Rochester Civic Theater are top sights worth seeing.

Kutzky Park

While there might not be top attractions in Kutzky Park, you can explore the larger area and discover places like Soldiers Field Veterans Memorial and Mayo Civic Center.

Slatterly Park

Slatterly Park might not have many top sights, but Rochester Art Center and Soldiers Field Veterans Memorial are two attractions nearby that you can check out.

Folwell

While there might not be top attractions in Folwell, you can explore the larger area and discover places like Soldiers Field Veterans Memorial and Apache Mall.

East Side Pioneers

If you're spending some time in East Side Pioneers, Rochester Art Center and Rochester Civic Theater are top sights worth seeing.

Top Historic Southwest Hotel Reviews

Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

10/10 Excellent
"This place is top notch! Our room had a kitchenette was very convenient for us while we were there. "
Koreen 7-night trip
Posted 1 day ago
Hyatt House Rochester/Mayo Clinic Area

Frequently asked questions

What is Historic Southwest like?
Guests are sure to enjoy their time checking out all that Rochester's Historic Southwest neighborhood has to offer. Be sure to check out Soldiers Field Veterans Memorial and Plummer House as part of your Historic Southwest travel plans.
What's the best accommodation in Historic Southwest?
Based on Expedia customer reviews, Hotel Indigo Rochester – Mayo Clinic Area by IHG is the highest ranked property in Historic Southwest. This hotel is a short 6-minute walk from Mayo Clinic, and it offers a restaurant and a fitness center. Other favorite options in the area include Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area and Hilton Garden Inn Rochester Downtown, MN.
How many hotels can I expect to find in the Historic Southwest area?
If you're searching for places to stay in Rochester, choose from one of Expedia's 12 hotels and other accommodations in Historic Southwest.
If I need to cancel my hotel reservation in Historic Southwest, will I receive a refund?
Yes, most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review top deals in Historic Southwest.
Where can I learn more about changing or cancelling my trip to Historic Southwest?
For additional details about rescheduling or cancelling your trip to Historic Southwest, go to https://www.expedia.com/service/.
What is there to do in this Rochester neighborhood?
A few attractions you might want to check out while you're in Historic Southwest are Soldiers Field Veterans Memorial and Plummer House. When you're sightseeing in Rochester, Soldiers Field Golf Course and Plummer Building are also worth a stop.

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