Photo by Caroline Nunez

Find hotels in Hartsville, SC from ￥8,561

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 9 - Dec 10
Tomorrow
Dec 10 - Dec 11
This weekend
Dec 12 - Dec 14
Next weekend
Dec 19 - Dec 21

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Hartsville hotels

Free daily continental breakfast
Fairfield Inn by Marriott Hartsville

Fairfield Inn by Marriott Hartsville

2.5 star property
Hartsville
8.6 out of 10, Excellent, (676)
"Good for overnight stay. Breakfast was a little disappointing….not much variety and hot food was warm at best. Room was very nice. Not familiar with area but hotel is in middle of downtown. "
United States
Lon
The price is ￥13,110
￥14,684 total
includes taxes & fees
Dec 20 - Dec 21
Fairfield Inn by Marriott Hartsville
Free daily buffet breakfast
Hampton Inn & Suites Hartsville

Hampton Inn & Suites Hartsville

2.5 star property
Hartsville
9.2 out of 10, Wonderful, (478)
"Nice clean hotel. Comfortable beds, nice amenities."
United States
Peggyanne
The price is ￥18,570
￥20,800 total
includes taxes & fees
Dec 19 - Dec 20
Hampton Inn & Suites Hartsville
Free daily continental breakfast
The Landmark Inn

The Landmark Inn

2.5 star property
Hartsville
7.0 out of 10, Good, (313)
"Great staff"
United States
Thomas
The price is ￥11,217
￥13,108 total
includes taxes & fees
Dec 10 - Dec 11
The Landmark Inn
Rooftop terrace
The Mantissa Hotel

The Mantissa Hotel

3.0 star property
Hartsville
9.2 out of 10, Wonderful, (270)
"Very nice spacious rooms friendly staff"
United States
Duane
The price is ￥23,220
￥26,006 total
includes taxes & fees
Dec 17 - Dec 18
The Mantissa Hotel
Lobby
Quality Inn Hartsville

Quality Inn Hartsville

2.5 star property
Hartsville
6.2 out of 10, (327)
"Lady at desk was plesant and helpful. Sstart3ed to ask for our money back"
United States
Cynthia
The price is ￥9,793
￥11,080 total
includes taxes & fees
Dec 23 - Dec 24
Quality Inn Hartsville
Lobby
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 star property
Florence
9.2 out of 10, Wonderful, (1161)
"Enjoyed our stay there. "
United States
Cathy
The price is ￥15,758
￥17,649 total
includes taxes & fees
Dec 28 - Dec 29
Comfort Inn & Suites Florence Center Area
Exterior
Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95

2.5 star property
Florence
9.0 out of 10, Wonderful, (810)
"Clean room, courteous staff and easy access to and from highway."
United States
Joe
The price is ￥16,451
￥18,425 total
includes taxes & fees
Dec 16 - Dec 17
Hampton Inn & Suites Florence-North-I-95
Exterior
Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG

3.0 star property
Florence
9.4 out of 10, Exceptional, (924)
"Friendly staff, great breakfast, beautiful ammenities!"
United States
Brandi
The price is ￥20,970
￥23,485 total
includes taxes & fees
Dec 14 - Dec 15
Staybridge Suites Florence - Civic Center by IHG
Exterior
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 star property
Florence
9.0 out of 10, Wonderful, (2197)
"Breakfast was great, room very clean ."
United States
Leann
The price is ￥14,644
￥16,401 total
includes taxes & fees
Dec 23 - Dec 24
Park Inn by Radisson Florence, SC
Lobby
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2.0 star property
Florence
8.6 out of 10, Excellent, (2479)
"I nice place to stay, very quiet, good breakfast, nice staff, spotless room. "
United States
Timothy
The price is ￥9,675
￥10,836 total
includes taxes & fees
Dec 10 - Dec 11
Howard Johnson by Wyndham Florence
View from property
Residence Inn Marriott Florence

Residence Inn Marriott Florence

3.0 star property
Florence
8.8 out of 10, Excellent, (470)
"Clean rooms and nice size suite area. "
United States
Yolanda
The price is ￥14,787
￥16,561 total
includes taxes & fees
Dec 14 - Dec 15
Residence Inn Marriott Florence
Exterior
La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

3.0 star property
Florence
8.0 out of 10, Very Good, (1678)
"Th room was nice comfortable breakfast was good and the people were very friendly "
United States
George
The price is ￥15,423
￥17,272 total
includes taxes & fees
Dec 23 - Dec 24
La Quinta Inn & Suites by Wyndham Florence
Desk, iron/ironing board, free WiFi, bed sheets
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 star property
Florence
6.8 out of 10, (1001)
"Clean rooms and wonderful staff "
United States
Rita
The price is ￥9,659
￥10,818 total
includes taxes & fees
Dec 10 - Dec 11
Days Inn by Wyndham Florence Near Civic Center
Premium bedding, in-room safe, desk, iron/ironing board
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 star property
Florence
7.8 out of 10, Good, (1254)
"Room was spotless, bed extremely comfortable and staff was very helpful and courteous. Would DEFINITELY stay there again. "
United States
Tim
The price is ￥12,568
￥14,076 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Quality Inn & Suites Florence Civic Center
View from property
Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20

2.5 star property
Florence
9.0 out of 10, Wonderful, (547)
"Good breakfast and room service "
United States
Indira
The price is ￥16,701
￥18,705 total
includes taxes & fees
Dec 14 - Dec 15
Fairfield Inn & Suites by Marriott Florence I-20
Free daily full breakfast
Springhill Suites by Marriott Cheraw

Springhill Suites by Marriott Cheraw

3.0 star property
Cheraw
9.4 out of 10, Exceptional, (279)
"Great room and hotel. Would definitely recommend and stay again."
United States
Brian
The price is ￥19,006
￥21,288 total
includes taxes & fees
Dec 11 - Dec 12
Springhill Suites by Marriott Cheraw
Indoor pool
Courtyard by Marriott Florence

Courtyard by Marriott Florence

3.0 star property
Florence
7.8 out of 10, Good, (698)
"Room was good, and the restaurant had amazing drinks and the wings and salad was great. Indoor pool was great "
United States
James H
The price is ￥15,051
￥16,856 total
includes taxes & fees
Dec 21 - Dec 22
Courtyard by Marriott Florence
Desk, blackout drapes, iron/ironing board, free WiFi
SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence

3.0 star property
Florence
8.6 out of 10, Excellent, (966)
"Easy check-in. Nice room. "
United States
Tim
The price is ￥16,500
￥18,480 total
includes taxes & fees
Dec 14 - Dec 15
SpringHill Suites by Marriott Florence
Terrace/patio
Home2 Suites by Hilton Florence, SC

Home2 Suites by Hilton Florence, SC

3.0 star property
Florence
8.2 out of 10, Very Good, (1007)
"Clean room, good location, quick checkin"
United States
Brian
The price is ￥16,078
￥18,008 total
includes taxes & fees
Dec 15 - Dec 16
Home2 Suites by Hilton Florence, SC
Exterior
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

2.5 star property
Florence
8.6 out of 10, Excellent, (1001)
"Room was clean, staff was courteous and breakfast was great !"
United States
Angela
The price is ￥17,760
￥19,891 total
includes taxes & fees
Dec 14 - Dec 15
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Stay near popular Hartsville attractions

Kalmia Gardens

4.0/5 (27 reviews)
Explore the great outdoors at Kalmia Gardens, a lovely green space in Hartsville. You'll find more to see and do in this walkable area.
See properties

Coker College

4.2/5 (59 reviews)
Take a campus tour or just explore the area of Coker College, during your trip to Hartsville. You'll find more to see and do in this walkable area.
See properties

Learn more about Hartsville

Stroll along the scenic Black Creek, where kayakers glide past historic buildings and lush parks. Sonoco Park's trails and Kalmia Gardens' blooms offer peaceful retreats, while Coker University's campus adds a vibrant collegiate atmosphere to this charming Southern town.

See all hotels in Hartsville
The Midnight Rooster is my go to spot in my hometown of Hartsville, SC. Great brunch and coffee! Love the courtyard!
Photo by Caroline Nunez
Open Photo by Caroline Nunez

Top Hartsville Hotel Reviews

The Landmark Inn

The Landmark Inn

10/10 Excellent
"Had a late check in @11pm. Front desk rep was friendly and professional. Check in was quick. Room was very clean. Bathroom was very clean. Sheets and pillows were clean and bed was very comfortable. No hassle about late checkout. Cleaning staff were very respectful and courteous. Excellent stay. I recommend The Landmark in Hartsville, SC. I will definitely be staying here again. "
Keechon 1-night trip
Posted 2 days ago
The Landmark Inn

More cheap stays in Hartsville

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2038 W Lucas Street Florence SC
The price is ￥9,675 per night from Dec 10 to Dec 11
￥9,675
￥10,836 total
Dec 10 - Dec 11
includes taxes & fees
8.6/10 Excellent! (2,476 reviews)

Frequently asked questions

What's the best place to stay in Hartsville?
Hampton Inn & Suites Hartsville is ranked highly by Expedia customers. This hotel offers free breakfast and an outdoor pool. Reviews from our site also recommend Fairfield Inn by Marriott Hartsville and The Landmark Inn as top options for your trip. See all available top hotels, or vacation rentals in Hartsville.
What are some of the best vacation rentals in Hartsville?
Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's: This vacation home rental outside of Hartsville offers a fireplace, a patio, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the garden in this rental home to help you unwind. See all vacation rentals in Hartsville.
If I need to cancel my hotel reservation in Hartsville, will I receive a refund?
Yes, you'll find most hotel room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Hartsville.
Where can I learn more about changing or cancelling my trip to Hartsville?
For additional details about updating your trip to Hartsville or cancelling it, click here.
What is the favorite LGBTQ-friendly accommodation in Hartsville?
Fairfield Inn by Marriott Hartsville is a top LGBTQ-friendly hotel that features free breakfast and free WiFi. Hampton Inn & Suites Hartsville is another good option for your stay. See all available hotels listed as LGBTQ-friendly in Hartsville.
What's the best pet-friendly place to stay in Hartsville?
Hampton Inn & Suites Hartsville is a top hotel for people traveling with their pets, and offers an outdoor pool and a fitness center for its human guests. Other good choices for you and your pet include Quality Inn and The Landmark Inn. See more pet-friendly hotel accommodations in Hartsville.
Where is the best hotel to stay with easy access to Coker College?
Adjacent to Coker College, Fairfield Inn by Marriott Hartsville is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an outdoor pool. Other good options close by include Hampton Inn & Suites Hartsville, SC and The Mantissa Hotel.
What about the best place to stay close to Kalmia Gardens?
One of the top choices for your stay is Fairfield Inn by Marriott Hartsville, located 2.7 mi (4.3 km) from Kalmia Gardens, and this hotel offers free breakfast and an outdoor pool. Hampton Inn & Suites Hartsville, SC and The Mantissa Hotel are two other good choices within a few miles.
What are some accommodations with pools in Hartsville?
Hampton Inn & Suites Hartsville is a top hotel with a pool, free buffet breakfast, and free WiFi. View all hotels with pools in Hartsville.
What's the top hotel in Hartsville with an on-site water park or a water park nearby?
Quality Inn is a popular hotel featuring water park access, a seasonal outdoor pool, and free parking. You'll find Neptune Island Waterpark within 3 minutes by car. Check out all hotels with or near waterparks in Hartsville.
What is the best accommodation for staying close to Florence Regional Airport (FLO)?
Hyatt Place Florence Downtown is one of the top choices for your stay and is a popular 3-star hotel featuring a restaurant and an outdoor pool. It's located 2.2 mi (3.5 km) from Florence Regional Airport. Other good choices near the airport include Hotel Florence, an Ascend Hotel Collection Member and Baymont Inn & Suites Florence by Wyndham.
How is it staying in Hartsville?
Visitors to Hartsville are sure to enjoy the restaurants. Tourists can also enjoy the city's university setting and shopping. In Hartsville, there are 17 hotels and other accommodations to choose from. Find out more about Hartsville.
What should I see while I'm in Hartsville?
Cultural venues include Hartsville Museum and Center Theatre. Landmarks like Kalmia Gardens and East Home Avenue Historic District might be worth a visit. The picturesque setting of Byerly Park and Segars-McKinnon Heritage Preserve exemplify the area's natural beauty. Check out what more to see and do in Expedia's Hartsville guide.
What's the seasonal weather like in Hartsville?
The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and February with an average of 49°F. Average annual precipitation for Hartsville is 52 inches.

Explore a world of travel with Expedia