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Find hotels in Hartsville, SC from ￥10,837

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Our top choices for Hartsville hotels

Rooftop terrace
The Mantissa Hotel

The Mantissa Hotel

The Mantissa Hotel
3.0 star property
Hartsville
9.2 out of 10, Wonderful, (270)
Discover stylish comfort at this Hartsville retreat with free breakfast, WiFi, and parking. After a workout in the fitness center, unwind at the rooftop terrace or bar. Located near Hartsville Museum and Center Theatre with attentive staff to assist.
"Very nice spacious rooms friendly staff"
United States
Duane
The price is ￥23,223
￥26,009 total
includes taxes & fees
Dec 22 - Dec 23
The Mantissa Hotel
Free daily buffet breakfast
Hampton Inn & Suites Hartsville

Hampton Inn & Suites Hartsville

Hampton Inn & Suites Hartsville
2.5 star property
Hartsville
9.2 out of 10, Wonderful, (479)
This Hampton Inn & Suites offers free breakfast, WiFi, and parking in Hartsville. Relax on the terrace after visiting the East Home Avenue Historic District. Rooms include convenient sofa beds and refrigerators, while the helpful staff ensures a pleasant stay.
"Staff was very friendly and accommodating!! Rooms were very clean! "
United States
Julia
The price is ￥18,573
￥20,803 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Hampton Inn & Suites Hartsville
Free daily continental breakfast
Fairfield Inn by Marriott Hartsville

Fairfield Inn by Marriott Hartsville

Fairfield Inn by Marriott Hartsville
2.5 star property
Hartsville
8.6 out of 10, Excellent, (677)
Dive into the tranquil atmosphere at this Hartsville hotel featuring a 24-hour fitness center and outdoor pool. Enjoy complimentary breakfast, WiFi, and parking while staying near East Home Avenue Historic District and local dining options.
"Good for overnight stay. Breakfast was a little disappointing….not much variety and hot food was warm at best. Room was very nice. Not familiar with area but hotel is in middle of downtown. "
United States
Lon
The price is ￥13,111
￥14,685 total
includes taxes & fees
Dec 20 - Dec 21
Fairfield Inn by Marriott Hartsville
Free daily continental breakfast
The Landmark Inn

The Landmark Inn

The Landmark Inn
2.5 star property
Hartsville
7.0 out of 10, Good, (314)
Set along Hartsville's main thoroughfare, this welcoming motel offers a seasonal outdoor pool and free breakfast. Nearby hiking trails provide adventure while Hartsville Museum and historic districts await exploration just minutes away.
"Great staff"
United States
Thomas
The price is ￥11,218
￥13,110 total
includes taxes & fees
Dec 16 - Dec 17
The Landmark Inn
Lobby
Quality Inn Hartsville

Quality Inn Hartsville

Quality Inn Hartsville
2.5 star property
Hartsville
6.2 out of 10, (328)
This business-friendly hotel offers free breakfast, WiFi, and parking near Hartsville Museum. Splash in the water park or unwind at the seasonal pool before exploring nearby attractions like Memorial Library.
"Lady at desk was plesant and helpful. Sstart3ed to ask for our money back"
United States
Cynthia
The price is ￥9,780
￥11,066 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Quality Inn Hartsville
Indoor pool
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
2.5 star property
Florence
9.2 out of 10, Wonderful, (1004)
Located in Florence near Regal Swamp Fox and Florence Veterans Park, this welcoming hotel offers a refreshing indoor pool experience. Free breakfast, WiFi, and parking complement the business-friendly amenities and attentive staff that guests consistently praise.
"Very good breakfast & convenient location"
United States
Diedre
The price is ￥17,139
￥19,194 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Terrace/patio
Tru by Hilton Florence I-95

Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
2.5 star property
Florence
8.4 out of 10, Very Good, (1005)
This Florence hotel offers convenience with an indoor pool, fitness center, and in-room refrigerators. Just 15 minutes from Darlington Raceway and close to Palmetto Shores Lake, guests appreciate the helpful staff, clean rooms, and complimentary parking.
"Hotel was clean , friendly staff"
United States
Gabriela
The price is ￥14,210
￥16,461 total
includes taxes & fees
Dec 21 - Dec 22
Tru by Hilton Florence I-95
View from property
Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
2.5 star property
Florence
9.0 out of 10, Wonderful, (550)
Conveniently located near Florence Veterans Park and Magnolia Mall, this hotel offers free breakfast and WiFi. The indoor pool provides year-round relaxation, while the attentive staff ensures a pleasant stay for business travelers.
"Clean room, professional and courteous staff. "
United States
Felicia
The price is ￥16,080
￥18,011 total
includes taxes & fees
Dec 21 - Dec 22
Fairfield Inn & Suites by Marriott Florence I-20
Front of property - evening/night
Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
3.0 star property
Florence
8.8 out of 10, Excellent, (1006)
Embrace comfort in this downtown Florence hotel with an outdoor pool, restaurant, and 24-hour fitness center. Just 5 minutes from Florence Regional Airport and a 16-minute walk to Florence Station, you'll find sofa beds and refrigerators in each clean, well-appointed room.
"Great stay"
United States
Michaelle
The price is ￥15,581
￥17,451 total
includes taxes & fees
Dec 22 - Dec 23
Hyatt Place Florence Downtown
Bar (on property)
Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
3.0 star property
Florence
8.8 out of 10, Excellent, (603)
This spa hotel features deep-tissue massages and body wraps in a convenient location near Florence Station. Enjoy meals at Victors Bistro, unwind at the bar, or stay active in the 24-hour fitness center. Free WiFi and parking enhance your relaxing South Carolina getaway.
"Special place. Great staff with an outstanding restaurant "
United States
John D
The price is ￥20,315
￥22,754 total
includes taxes & fees
Dec 21 - Dec 22
Hotel Florence, Tapestry Collection by Hilton
Terrace/patio
Home2 Suites by Hilton Florence, SC

Home2 Suites by Hilton Florence, SC

Home2 Suites by Hilton Florence, SC
3.0 star property
Florence
8.2 out of 10, Very Good, (1001)
"Clean room, good location, quick checkin"
United States
Brian
The price is ￥16,079
￥18,009 total
includes taxes & fees
Dec 23 - Dec 24
Home2 Suites by Hilton Florence, SC
Exterior
Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
3.0 star property
Florence
9.4 out of 10, Exceptional, (926)
Enjoy convenient amenities at this Florence hotel featuring an outdoor pool and children's pool. The restaurant serves tasty meals, while rooms include refrigerators and microwaves. Located close to Regal Swamp Fox and Florence Veterans Park with free WiFi and parking.
"Friendly staff, great breakfast, beautiful ammenities!"
United States
Brandi
The price is ￥18,386
￥20,593 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Staybridge Suites Florence - Civic Center by IHG
Exterior
Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
2.5 star property
Florence
9.0 out of 10, Wonderful, (813)
Located just 10 minutes from Florence Regional Airport, this welcoming hotel offers free breakfast and parking. Unwind in the hot tub after working out in the fitness center, or enjoy a refreshing drink at the coffee shop. Palmetto Shores Lake and tennis center are nearby attractions.
"The hotel was excellent. In fact we stayed 2 different nights on our travel up and down Rt 95. Breakfast was great and hotel very clean and quiet. "
United States
Cynthia
The price is ￥16,827
￥18,846 total
includes taxes & fees
Jan 15 - Jan 16, 2026
Hampton Inn & Suites Florence-North-I-95
Lobby
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
Florence
9.2 out of 10, Wonderful, (1165)
Located near Florence Veterans Park and Magnolia Mall, this welcoming hotel offers free breakfast and WiFi. Guests love the comfortable beds and can enjoy the 24-hour fitness center or seasonal outdoor pool after exploring nearby attractions.
"Enjoyed our stay there. "
United States
Cathy
The price is ￥15,422
￥17,274 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Comfort Inn & Suites Florence Center Area
Exterior
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
2.5 star property
Florence
9.0 out of 10, Wonderful, (2195)
Experience comfort and convenience at this Florence hotel, just minutes from the train station. Enjoy a daily buffet breakfast, free WiFi, and well-equipped fitness center. Nearby attractions include Dr. Eddie Floyd Tennis Center and Palmetto Shores Lake.
"Breakfast was great, room very clean ."
United States
Leann
The price is ￥13,322
￥14,920 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Park Inn by Radisson Florence, SC
Exterior
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
2.5 star property
Florence
8.6 out of 10, Excellent, (1005)
Near Eastern Carolina Agricultural Fairgrounds, this Florence hotel offers a refreshing indoor pool and 24-hour fitness center. Business travelers appreciate the complimentary WiFi, parking, and hot breakfast, while all guests enjoy clean rooms and helpful staff.
"Room was clean, staff was courteous and breakfast was great !"
United States
Angela
The price is ￥17,762
￥19,893 total
includes taxes & fees
Dec 21 - Dec 22
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Front of property
Best Western Inn

Best Western Inn

Best Western Inn
2.5 star property
Florence
7.6 out of 10, Good, (1002)
Serene atmosphere and helpful staff make this Florence hotel an ideal base. Enjoy the seasonal outdoor pool, free continental breakfast, and easy access to Dr. Eddie Floyd Tennis Center. Just 9 minutes from Florence Regional Airport with complimentary WiFi and parking.
"Spotless room and courteous staff"
United States
Krusaundra
The price is ￥13,867
￥15,532 total
includes taxes & fees
Dec 16 - Dec 17
Best Western Inn
Free daily on-the-go breakfast
Homewood Suites by Hilton Florence

Homewood Suites by Hilton Florence

Homewood Suites by Hilton Florence
3.0 star property
Florence
8.4 out of 10, Very Good, (657)
Offering a 24-hour fitness center and complimentary breakfast, this hotel sits conveniently close to Regal Swamp Fox and Florence Veterans Park. Clean rooms, free WiFi and parking complement the exceptional staff service that guests consistently praise.
"The staff was amazing and the hotel is pretty fresh in terms of amenities "
United States
Shahid
The price is ￥14,833
￥17,228 total
includes taxes & fees
Dec 21 - Dec 22
Homewood Suites by Hilton Florence
Lobby sitting area
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
2.5 star property
Florence
8.0 out of 10, Very Good, (25)
"Friendly staff and clean environment "
United States
john
The price is ￥14,210
￥16,529 total
includes taxes & fees
Dec 21 - Dec 22
Spark by Hilton Florence North I-95, SC
Exterior
Comfort Suites Florence I-95

Comfort Suites Florence I-95

Comfort Suites Florence I-95
2.5 star property
Florence
8.4 out of 10, Very Good, (1003)
Discover this Florence hotel with complimentary breakfast, WiFi, and parking just minutes from Darlington Raceway. Unwind in the indoor pool or fitness center after exploring nearby Palmetto Shores Lake. Guests consistently praise the attentive staff and convenient location.
"Good place to stay, good price"
United States
Carlos
The price is ￥15,986
￥18,528 total
includes taxes & fees
Dec 28 - Dec 29
Comfort Suites Florence I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Great weekend hotel deals in Hartsville, SC

Showing deals for:Dec 26 - Dec 28

Image gallery for Lakeside 2-bedroom RV in charming Hartsville with AC, WiFi

Interior

Lakeside 2-bedroom RV in charming Hartsville with AC, WiFi

Hartsville
8.0/10Very Good (1 review)
10% off
Price is ￥14,023
￥44,157 total
includes taxes & fees
Lakeside 2-bedroom RV in charming Hartsville with AC, WiFi
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Stay near popular Hartsville attractions

Kalmia Gardens

4.0/5 (27 reviews)
Explore the great outdoors at Kalmia Gardens, a lovely green space in Hartsville. You'll find more to see and do in this walkable area.
See properties

Coker College

4.2/5 (59 reviews)
Take a campus tour or just explore the area of Coker College, during your trip to Hartsville. You'll find more to see and do in this walkable area.
See properties

Learn more about Hartsville

Stroll along the scenic Black Creek, where kayakers glide past historic buildings and lush parks. Sonoco Park's trails and Kalmia Gardens' blooms offer peaceful retreats, while Coker University's campus adds a vibrant collegiate atmosphere to this charming Southern town.

See all hotels in Hartsville
The Midnight Rooster is my go to spot in my hometown of Hartsville, SC. Great brunch and coffee! Love the courtyard!
Photo by Caroline Nunez
Open Photo by Caroline Nunez

Top Hartsville Hotel Reviews

Residence Inn Marriott Florence

Residence Inn Marriott Florence

10/10 Excellent
"Yes our stay was great big variety on breakfast clean hotel rooms nice to have a kitchen had a great day"
Marialinda 2-night trip
Posted 22 hours ago
Residence Inn Marriott Florence

More cheap stays in Hartsville

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2038 W Lucas Street Florence SC
The price is ￥9,676 per night from Dec 16 to Dec 17
￥9,676
￥10,837 total
Dec 16 - Dec 17
includes taxes & fees
8.6/10 Excellent! (2,486 reviews)

Frequently asked questions

What's the best place to stay in Hartsville?
The Mantissa Hotel is ranked highly by Expedia customers. This hotel offers free breakfast and a restaurant. Reviews from our site also recommend Fairfield Inn by Marriott Hartsville and The Landmark Inn as top options for your trip. See all available top hotels, or vacation rentals in Hartsville.
What are some of the best vacation rentals in Hartsville?
Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's: This vacation home rental outside of Hartsville offers a fireplace, a patio, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the garden in this rental home to help you unwind. See all vacation rentals in Hartsville.
If I need to cancel my hotel reservation in Hartsville, will I receive a refund?
Yes, you'll find most hotel room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Hartsville.
Where can I learn more about changing or cancelling my trip to Hartsville?
For additional details about updating your trip to Hartsville or cancelling it, click here.
What is the favorite LGBTQ-friendly accommodation in Hartsville?
Fairfield Inn by Marriott Hartsville is a top LGBTQ-friendly hotel that features free breakfast and free WiFi. Hampton Inn & Suites Hartsville is another good option for your stay. See all available hotels listed as LGBTQ-friendly in Hartsville.
What's the best pet-friendly place to stay in Hartsville?
Hampton Inn & Suites Hartsville is a top hotel for people traveling with their pets, and offers an outdoor pool and a fitness center for its human guests. Other good choices for you and your pet include The Landmark Inn and Quality Inn Hartsville. See more pet-friendly hotel accommodations in Hartsville.
Where is the best hotel to stay with easy access to Coker College?
Adjacent to Coker College, Fairfield Inn by Marriott Hartsville is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an outdoor pool. Other good options close by include Hampton Inn & Suites Hartsville, SC and The Mantissa Hotel.
What about the best place to stay close to Kalmia Gardens?
One of the top choices for your stay is Fairfield Inn by Marriott Hartsville, located 2.7 mi (4.3 km) from Kalmia Gardens, and this hotel offers free breakfast and an outdoor pool. Hampton Inn & Suites Hartsville, SC and The Mantissa Hotel are two other good choices within a few miles.
What are some accommodations with pools in Hartsville?
Hampton Inn & Suites Hartsville is a top hotel with a pool, free buffet breakfast, and free WiFi. View all hotels with pools in Hartsville.
What's the top hotel in Hartsville with an on-site water park or a water park nearby?
Quality Inn Hartsville is a popular hotel featuring water park access, a seasonal outdoor pool, and free parking. You'll find Neptune Island Waterpark within 5 minutes by car. Check out all hotels with or near waterparks in Hartsville.
What is the best accommodation for staying close to Florence Regional Airport (FLO)?
Hyatt Place Florence Downtown is one of the top choices for your stay and is a popular 3-star hotel featuring a restaurant and an outdoor pool. It's located 2.2 mi (3.5 km) from Florence Regional Airport. Other good choices near the airport include Hotel Florence, an Ascend Hotel Collection Member and Baymont Inn & Suites Florence by Wyndham.
How is it staying in Hartsville?
Visitors to Hartsville are sure to enjoy the restaurants. Tourists can also enjoy the city's university setting and shopping. In Hartsville, there are 19 hotels and other accommodations to choose from. Find out more about Hartsville.
What should I see while I'm in Hartsville?
Cultural venues include Hartsville Museum and Center Theatre. Landmarks like Kalmia Gardens and East Home Avenue Historic District might be worth a visit. The picturesque setting of Byerly Park and Segars-McKinnon Heritage Preserve exemplify the area's natural beauty. Check out what more to see and do in Expedia's Hartsville guide.
What's the seasonal weather like in Hartsville?
The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and February with an average of 49°F. Average annual precipitation for Hartsville is 52 inches.

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