A brick wall with a street sign reading 'GREENVILLE ST.' and a black street lamp.

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Check prices for these dates

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Nov 6 - Nov 8
Next weekend
Nov 13 - Nov 15

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Our top choices for Greenville hotels

A modern living room with a fireplace, blue sofa, red chairs, and a flat-screen TV mounted on a textured wall.

1. Comfort Inn & Suites Greenville I-70

Comfort Inn & Suites Greenville I-70
2.5 star property
Greenville
8.4 out of 10, Very good, (486 reviews)
"Very nice and quiet hotel. Breakfast was exceptional, we really enjoyed our stay."
United States
Debbie
The price is ļæ„16,315
ļæ„18,106 total
includes taxes & fees
Nov 8 - Nov 9
Comfort Inn & Suites Greenville I-70
A hotel room with a bed, a television, a desk, and a chair.

2. Super 8 by Wyndham Greenville

Super 8 by Wyndham Greenville
2.0 star property
Greenville
8.0 out of 10, Very good, (859 reviews)
"Clean comfortable room right off the highway. Cute town with good restaurant. Fit our needs perfectly."
United States
Sharon
The price is ļæ„10,927
ļæ„12,127 total
includes taxes & fees
Nov 8 - Nov 9
Super 8 by Wyndham Greenville
A hotel room with two beds, a desk, and a chair.

3. SureStay Hotel by Best Western Greenville

SureStay Hotel by Best Western Greenville
2.5 star property
Greenville
7.4 out of 10, Good, (624 reviews)
"good breakfest"
United States
jesse
The price is ļæ„8,636
ļæ„9,584 total
includes taxes & fees
Nov 23 - Nov 24
SureStay Hotel by Best Western Greenville
A hotel room with a bed, bedside tables, a desk, a chair, a TV, and a window with curtains.

4. Budget Inn Motel

Budget Inn Motel
2.0 star property
Greenville
7.0 out of 10, Good, (200 reviews)
"Great for the price you pay"
United States
Steven
The price is ļæ„7,620
ļæ„8,457 total
includes taxes & fees
Nov 10 - Nov 11
Budget Inn Motel
A modern hotel lobby with a reception desk, seating area, and a large wall mural.

5. Holiday Inn Express & Suites Vandalia by IHG

Holiday Inn Express & Suites Vandalia by IHG
2.5 star property
Vandalia
8.8 out of 10, Excellent, (869 reviews)
"Room was clean, parking was adequate. Breakfast was very good"
United States
Russell
The price is ļæ„16,701
ļæ„18,201 total
includes taxes & fees
Nov 8 - Nov 9
Holiday Inn Express & Suites Vandalia by IHG
A hotel dining area with multiple tables and chairs, a reception desk, and a clock on the wall.

6. Hampton Inn by Hilton Litchfield

Hampton Inn by Hilton Litchfield
2.5 star property
Litchfield
9.0 out of 10, Wonderful, (699 reviews)
"Good room and breakfast"
United States
Aimee
The price is ļæ„16,607
ļæ„18,264 total
includes taxes & fees
Nov 8 - Nov 9
Hampton Inn by Hilton Litchfield
A neatly made bed with a patterned bedspread, a framed picture above it, a chair, a lamp, and a checkered floor.

7. Powhatan Motel

Powhatan Motel
2.5 star property
Pocahontas
8.6 out of 10, Excellent, (230 reviews)
"Basic, old style motel. Room was clean and food was excellent."
United States
Bob
The price is ļæ„15,244
ļæ„16,156 total
includes taxes & fees
Nov 3 - Nov 4
Powhatan Motel
A lobby with a wooden staircase, a desk with a computer, and patterned armchairs.

8. Ramada by Wyndham Vandalia

Ramada by Wyndham Vandalia
2.0 star property
Vandalia
7.8 out of 10, Good, (876 reviews)
"Staff is always helpful and welcoming."
United States
Samantha
The price is ļæ„12,605
ļæ„13,738 total
includes taxes & fees
Nov 3 - Nov 4
Ramada by Wyndham Vandalia
A hotel room with a bed, a desk with a chair, a sofa, and a small table.

9. Quality Inn & Suites Vandalia near I-70 and Hwy 51

Quality Inn & Suites Vandalia near I-70 and Hwy 51
2.5 star property
Vandalia
8.2 out of 10, Very good, (1,002 reviews)
"It is an older property but I thought it was very nice"
United States
Colleen
The price is ļæ„11,344
ļæ„12,362 total
includes taxes & fees
Nov 3 - Nov 4
Quality Inn & Suites Vandalia near I-70 and Hwy 51
An indoor swimming pool with a clear view of the sky through the roof, surrounded by red lounge chairs and a few tables.

10. Baymont by Wyndham Litchfield

Baymont by Wyndham Litchfield
2.5 star property
Litchfield
8.2 out of 10, Very good, (1,002 reviews)
"Nice staff and nice place!"
United States
Kathy
The price is ļæ„14,968
ļæ„16,462 total
includes taxes & fees
Nov 3 - Nov 4
Baymont by Wyndham Litchfield
A multi-story hotel with a central entrance, illuminated by exterior lights, and a clear sky in the background.

11. Best Western Plus Centralia Hotel & Suites

Best Western Plus Centralia Hotel & Suites
2.5 star property
Centralia
9.6 out of 10, Exceptional, (686 reviews)
"We stayed here with 2 adults and 3 kids and it was perfect. We highly recommend staying here"
United States
Jeremy
The price is ļæ„21,901
ļæ„24,524 total
includes taxes & fees
Nov 3 - Nov 4
Best Western Plus Centralia Hotel & Suites
A modern living room with patterned carpet, two sofas, a coffee table, and a TV.

12. Super 8 by Wyndham Staunton

Super 8 by Wyndham Staunton
2.0 star property
Staunton
8.6 out of 10, Excellent, (825 reviews)
"It was a good location and served our needs for a night"
United States
Shelby
The price is ļæ„13,550
ļæ„15,037 total
includes taxes & fees
Nov 5 - Nov 6
Super 8 by Wyndham Staunton
A spacious living room with a fireplace, a television, and a modern chandelier.

13. Quality Inn Litchfield Route 66

Quality Inn Litchfield Route 66
2.5 star property
Litchfield
8.6 out of 10, Excellent, (719 reviews)
"Good location. Couch was broken down but otherwise a good stay."
United States
Franklin
The price is ļæ„12,857
ļæ„14,140 total
includes taxes & fees
Nov 22 - Nov 23
Quality Inn Litchfield Route 66
A hotel room with a large bed, a red bedspread, a bathtub, a nightstand with a lamp, and two framed pictures on the wall.

14. Seasons Inn & Suites Highland

Seasons Inn & Suites Highland
2.5 star property
Highland
8.0 out of 10, Very good, (698 reviews)
"Front desk was very helpful and friendly. Reasonably priced and clean."
United States
Jeffrey
The price is ļæ„14,145
ļæ„15,698 total
includes taxes & fees
Nov 29 - Nov 30
Seasons Inn & Suites Highland
A building with a covered entrance, stone pillars, and a bench outside.

15. Holiday Inn Express & Suites Litchfield West by IHG

Holiday Inn Express & Suites Litchfield West by IHG
2.5 star property
Litchfield
9.6 out of 10, Exceptional, (674 reviews)
"I enjoyed the proximity to Route 66 and the long sidewalk next to the prairie for long walks."
United States
Michael
The price is ļæ„19,380
ļæ„21,314 total
includes taxes & fees
Dec 2 - Dec 3
Holiday Inn Express & Suites Litchfield West by IHG
A hotel room with a bed, a desk, a chair, a table, a mirror, and a bathroom visible in the background.

16. Americas Best Value Inn Vandalia

Americas Best Value Inn Vandalia
2.0 star property
Vandalia
7.8 out of 10, Good, (221 reviews)
"Quiet, clean, convenient comfortable bed and a good breakfast of waffles, cereal, yogurt, and juice. Old building, but rooms well refurbished"
Canada
Paula
The price is ļæ„9,611
ļæ„10,474 total
includes taxes & fees
Nov 5 - Nov 6
Americas Best Value Inn Vandalia
A hotel room with a bed, desk, chair, lamp, TV, and a bathroom visible through an open door.

17. Motel 6 Litchfield, IL

Motel 6 Litchfield, IL
2.0 star property
Litchfield
7.2 out of 10, Good, (185 reviews)
"The man at the front desk was friendly, both at check in and check out."
United States
Pam
The price is ļæ„11,028
ļæ„12,129 total
includes taxes & fees
Nov 3 - Nov 4
Motel 6 Litchfield, IL
A riverside view with a gravel path and a building with a red facade.

18. Innkeeper Motel

Innkeeper Motel
2.0 star property
Hamel
7.6 out of 10, Good, (11 reviews)
"Older property with no extras, Clean and updated rooms."
United States
Timothy
The price is ļæ„9,628
ļæ„10,685 total
includes taxes & fees
Nov 22 - Nov 23
Innkeeper Motel
A hotel room with a bed, a chair, a small table, a lamp, a television, and a window with curtains.

19. Countryside Inn

Countryside Inn
2.0 star property
Hillsboro
5.6 out of 10, (41 reviews)
"The space is excellent and includes more than the usual room--full kitchen, for example. Staff are exceptionally welcoming and skilled. "
United States
Susanne
The price is ļæ„12,439
ļæ„13,681 total
includes taxes & fees
Nov 3 - Nov 4
Countryside Inn
A white door with the number 16, a mailbox, and a small light fixture on the left.

20. Lighthouse Lodge

Lighthouse Lodge
2.0 star property
Pocahontas
8.6 out of 10, Excellent, (30 reviews)
"Check-in as at the gas station directly next door. We arrived very late, but the store clerk was friendly and helpful. Room was clean and comfortable."
United States
Danica
The price is ļæ„13,188
ļæ„13,977 total
includes taxes & fees
Nov 3 - Nov 4
Lighthouse Lodge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Greenville attractions

Patriot's Park

8.4/10 (14 reviews)
This peaceful community park offers scenic trails around a serene lake, plus disc golf and playgrounds. Enjoy a morning walk through wooded areas to spot local wildlife or cast a line for some relaxing fishing.
See properties

Learn more about Greenville

Stroll through the historic downtown square where vintage storefronts house local shops and the 'World's Largest Mailbox' stands proudly. Outdoor enthusiasts can hike scenic trails at nearby Patriot's Park or catch a baseball game at Greenville College's field during spring season.

See all hotels in Greenville
A brick wall with a street sign reading 'GREENVILLE ST.' and a black street lamp.

Top Greenville Hotel Reviews

Comfort Inn & Suites Greenville I-70

Comfort Inn & Suites Greenville I-70

10/10 Excellent
"Room was comfy breakfast was great staff was very friendly and kind"
Melissa 2-night trip
Posted 11 hours ago
Comfort Inn & Suites Greenville I-70

More cheap stays in Greenville

Quality Inn Litchfield Route 66

Quality Inn Litchfield Route 66

1010 E Columbian Blvd N Litchfield IL
The price is ļæ„12,857 per night from Nov 22 to Nov 23
ļæ„12,857
ļæ„14,140 total
Nov 22 - Nov 23
includes taxes & fees
8.6/10 Excellent! (719 reviews)

Frequently asked questions

What's the best place to stay in Greenville?
Comfort Inn & Suites Greenville I-70 is one of the top choices for your stay based on our traveler data. This hotel offers free breakfast and an indoor pool. Other good choices for your trip include Super 8 by Wyndham Greenville and SureStay Hotel by Best Western Greenville. See all available top hotels, or vacation rentals in Greenville.
What are some of the best vacation home rentals in Greenville?
Private 7-Acre Multi Family Retreat Perfect for Reunions or Other Venues: Visitors like this Greenville vacation home rental. It offers an outdoor pool, a fireplace, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a balcony and a selection of games. Some other top choices in Greenville are THE NEST getaways&gatherings, beach/lake sleeps 20+ and The Beaumont Suite !. See all vacation rentals in Greenville.
If I need to cancel my hotel reservation in Greenville, will I receive a refund?
Yes, most hotel bookings are fully refundable if cancelled prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Greenville.
Where can I learn more about changing or cancelling my trip to Greenville?
For more details about picking new dates or cancelling your trip to Greenville, head over to our customer service page.
What's the best pet-friendly accommodation in Greenville?
SureStay Hotel by Best Western Greenville is a top hotel for people traveling with their pets, and offers an indoor pool and laundry facilities for its human guests. Super 8 by Wyndham Greenville is another option if you're bringing your pet along. See more pet-friendly hotel accommodations in Greenville.
What are some accommodations with pools in Greenville?
Comfort Inn & Suites Greenville I-70: Features buffet, an indoor pool, and free self parking. SureStay Hotel by Best Western Greenville and Private 7-Acre Multi Family Retreat Perfect for Reunions or Other Venues are two additional hotels with an onsite pool. View all hotels with pools in Greenville.
What's the best place to stay near Lambert-St. Louis International Airport (STL)?
Marriott St. Louis Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.5 km) from Lambert-St. Louis Intl. Airport. Other good choices within close proximity to the airport include Pear Tree Inn Airport - St. Louis - St. Ann, MO and Drury Inn & Suites St. Louis Airport.
How is it staying in Greenville?
Visitors to Greenville are sure to enjoy the restaurants. Tourists can also enjoy so much more including its golf courses. In Greenville, there are 9 hotels and other accommodations to choose from. Find out more about Greenville.
What should I see while I'm in Greenville?
A couple of favorite places to visit are Greenville Country Club and Patriot's Park. You'll also find Carlyle Lake and Silver Lake Park in the area. Check out what more to see and do in Expedia's Greenville guide.
What's the weather like in Greenville?
The hottest months are usually July and August with an average temp of 74Ā°F, while the coldest months are January and February with an average of 36Ā°F. Average annual precipitation for Greenville is 51 inches.

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