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Discover 378 East Side Pioneers hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Courtyard
EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
4.0 star property
9.6 out of 10, Exceptional, (586)
"Awesome"
The price is ￥16,349
per night
May 23 - May 24
EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
Aerial view
Kahler Inn and Suites - Mayo Clinic Area
3.5 star property
7.6 out of 10, Good, (1192)
"It was right across the street from where I needed to be at the Mayo. I liked that there was a restaurant in the hotel. Rooms are great but we stayed less than 12 hours. "
The price is ￥17,944
per night
May 17 - May 18
Kahler Inn and Suites - Mayo Clinic Area
Indoor pool
Kahler Grand Hotel
3.0 star property
8.2 out of 10, Very Good, (1003)
"This was a great place to stay if you are a patient at Mayo Clinic. It is quiet and very luxurious for the price. My only complaint was that the shower was kind of small, but that would not prevent me from staying there the next time I have to make the trip to the Mayor Clinic"
The price is ￥23,029
per night
May 17 - May 18
Kahler Grand Hotel
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Terrace/patio
Hyatt House Rochester/Mayo Clinic Area
3.0 star property
9.0 out of 10, Wonderful, (539)
"Easy and quick check-in. Staff is friendly and experienced. Their buffet breakfast has hot entrees, pastries, fruit and fruit juices, cereal, plus wonderful coffee. Clean rooms with walk-in showers. Covered parking is attached. Our decision is based on: close to Kutzky park, free covered parking and includes breakfast. . Our decision is based on: close to Kutzky park, free covered parking and includes breakfast."
The price is ￥17,620
per night
Jun 7 - Jun 8
Hyatt House Rochester/Mayo Clinic Area
Front of property
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3.0 star property
8.0 out of 10, Very Good, (1002)
"nice quiet, clean and comfortable. It’s just out of the the downtown area but a short drive to the heart of Rochester. My kids loved the pool and I enjoyed the hot tub. The gym is nice. Free breakfast was good (hot and cold options) nice eating area, all staff were nice. This hotel was the most affordable option in the Rochester area and it’s a great place. I’d definitely stay here again"
The price is ￥13,076
per night
May 19 - May 20
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Exterior
Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
3.5 star property
8.8 out of 10, Excellent, (533)
"Clean property close to the clinic "
The price is ￥18,207
per night
Jun 1 - Jun 2
Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
Exterior
Holiday Inn Express Rochester South - Mayo Area, an IHG Hotel
2.5 star property
8.6 out of 10, Excellent, (1000)
"Excellent stay, as usual. Friendly staff, clean rooms and comfy bed. "
The price is ￥14,057
per night
May 24 - May 25
Holiday Inn Express Rochester South - Mayo Area, an IHG Hotel
In-room safe, desk, iron/ironing board, free cribs/infant beds
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
2.0 star property
8.0 out of 10, Very Good, (1004)
"Great place to stay for the price. We had a room with two beds and a recliner. The room for was nice size for a Microtel. The window opened which was nice for fresh air at night. Like all older motels it could be updated. There is a gas station real close in case you need anything "
The price is ￥10,379
per night
May 19 - May 20
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
Terrace/patio
Hampton Inn Rochester-South
2.5 star property
9.0 out of 10, Wonderful, (1003)
"Great staff, clean room, friendly people. More parking or space for parking would have been more convenient for customers "
The price is ￥13,758
per night
Jun 16 - Jun 17
Hampton Inn Rochester-South
Blackout drapes, soundproofing, iron/ironing board, free WiFi
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 star property
8.2 out of 10, Very Good, (388)
"Very nice, family friendly hotel, & very convenient, walking distance to the Mall, restaurants, variety shopping areas. Great full breakfast served, & great staff. Fair price too. 👍 "
The price is ￥13,663
per night
May 20 - May 21
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
BBQ/picnic area
Residence Inn by Marriott Rochester Mayo Clinic Area South
3.0 star property
9.4 out of 10, Exceptional, (78)
"Separate rooms and the kitchen "
The price is ￥18,238
per night
May 23 - May 24
Residence Inn by Marriott Rochester Mayo Clinic Area South
Exterior
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
3.0 star property
9.0 out of 10, Wonderful, (615)
"A nice hotel at a reasonable rate. Our three night stay was very pleasant."
The price is ￥16,847
per night
May 25 - May 26
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Free daily buffet breakfast
TownePlace Suites by Marriott Rochester Mayo Clinic Area
3.0 star property
9.8 out of 10, Exceptional, (275)
"I appreciate the convenience of the location to Mayo Clinic. Staff were accommodating and friendly. Beds are very comfortable. "
The price is ￥18,238
per night
Jun 1 - Jun 2
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Exterior
Holiday Inn Express & Suites Rochester – Mayo Clinic Area, an IHG Hotel
2.5 star property
8.8 out of 10, Excellent, (606)
"Courteous helpful staff. Only negative is syreet noise fron nearby highway "
The price is ￥17,289
per night
May 18 - May 19
Holiday Inn Express & Suites Rochester – Mayo Clinic Area, an IHG Hotel
Terrace/patio
Home2 Suites by Hilton Rochester Mayo Clinic Area
3.0 star property
9.6 out of 10, Exceptional, (619)
"The service was great! The shuttle bus and driver were so helpful!"
The price is ￥19,575
per night
May 23 - May 24
Home2 Suites by Hilton Rochester Mayo Clinic Area
Lobby
Hilton Rochester Mayo Clinic Area
3.5 star property
9.6 out of 10, Exceptional, (334)
"All staff are nice and friendly "
The price is ￥26,144
per night
Jun 1 - Jun 2
Hilton Rochester Mayo Clinic Area
Indoor spa tub
Quality Inn near Medical Center
2.5 star property
8.0 out of 10, Very Good, (483)
"The staff were very friendly and helpful. The continental breakfast was good, had scrambled eggs, sausage and make your own waffles. It also had many extras: toast, bagels, hot and cold cereal and fruit. There were some minor repairs that needed to be done, but nothing that was disruptive to the comfort and safety of our stay. "
The price is ￥9,722
per night
May 22 - May 23
Quality Inn near Medical Center
Desk, iron/ironing board, free WiFi, bed sheets
Brentwood Inn & Suites
2.5 star property
8.6 out of 10, Excellent, (1002)
"I was in Rochester for surgery, and found the accommodations pleasant and quiet. The bathroom ceiling above the shower/tub needs attention; overall, I would stay here again."
The price is ￥16,847
per night
May 19 - May 20
Brentwood Inn & Suites
Lunch and dinner served, American cuisine
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
3.0 star property
8.2 out of 10, Very Good, (1001)
"This is our standby hotel for our trips 2-3 times each year to Mayo Clinic. They operate the main hotel and at least one former apartment building. We have stayed in both and the staff have always been great, making this a great value. I usually prefer more modern-looking hotels with more spacious rooms, but the location, service, price and great attached restaurant (Twigs) make it a great value. I have never taken the shuttle to Mayo since the several block distance makes it is a nice walk...
The price is ￥18,090
per night
May 30 - May 31
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Premium bedding, desk, iron/ironing board, free cribs/infant beds
Aspen Select
3.5 star property
8.6 out of 10, Excellent, (1000)
"Very close to Mayo Clinic. Across the street! Reasonable rate thru Expedia"
The price is ￥17,386
per night
May 17 - May 18
Aspen Select
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around East Side Pioneers

Hotels in top Rochester neighborhoods Learn more about East Side Pioneers
Rochester showing skyline and a city

Downtown Rochester

3 out of top 10 points of interest in this area
4.5/5(250 area reviews)

If you're spending some time in Downtown Rochester, Mayo Civic Center and Rochester Art Center are top sights worth seeing.

Find hotels in Downtown Rochester

East Side Pioneers hotels information

Number of reviews
14,204
Accommodation
378 hotels
Lowest Price
￥9,722
Highest Price
￥26,144

Frequently asked questions

What's it like in East Side Pioneers?

Travelers are sure to enjoy a stay in Rochester's East Side Pioneers neighborhood. Are you looking for East Side Pioneers travel tips? Be sure to check out Mayo Civic Center and Rochester Civic Theater while you're in the neighborhood.

What's a favorite place to stay in East Side Pioneers?

Based on Expedia customer reviews, Hilton Rochester Mayo Clinic Area is the highest ranked property in East Side Pioneers. This hotel is a short 3-minute walk from Mayo Civic Center, and it offers a full-service spa and 2 restaurants. Another favorite option in the neighborhood is Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel.

How many hotels will I be able to find in East Side Pioneers?

If you're searching for places to stay in Rochester, Expedia has something to meet your needs with 24 East Side Pioneers hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in East Side Pioneers, will I receive a refund?

Yes! You'll find that most hotel room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of booking. Enter your dates, click on "Search", then you can filter by "fully refundable" to review top deals in East Side Pioneers.

Where can I learn more about changing or cancelling my trip to East Side Pioneers?

To access more information about changing or cancelling your trip to East Side Pioneers, click here.

What can I see and do in this Rochester neighborhood?

Spend some time exploring the natural setting of East Side Pioneers with a visit to Mayo Park and Silver Lake Park. You could also plan a visit to Mayo Civic Center or Rochester Civic Theater while you're in the neighborhood. A few places to visit in the area around East Side Pioneers include Rochester Art Center, Shops University Square, and Soldiers Field Veterans Memorial. While you're out sightseeing, Soldiers Field Golf Course and Quarry Hill Nature Center are a couple of additional sights to visit in Rochester.

Recent reviews of East Side Pioneers hotels

AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

5/5 Excellent
"Loved they had a restaurant attached to the hotel"
A verified traveler from Waterloo stayed at AmericInn by Wyndham Rochester Near Mayo Clinic
Posted 3 days ago
AmericInn by Wyndham Rochester Near Mayo Clinic