Photo by Southernmost Illinois Tourism Bureau

Find hotels in Southern Illinois, IL from ¥8,781

Start date: Check-in selected.
To Date
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Compare 1,080 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Days Inn by Wyndham Mount Vernon

2.0 star property
6.6 out of 10, (1007)
"Staff was very friendly "
The price is ¥9,362
¥10,688 total
includes taxes & fees
Sep 29 - Sep 30
Days Inn by Wyndham Mount Vernon

Drury Plaza Hotel Mt. Vernon

3.0 star property
9.6 out of 10, Exceptional, (1468)
"Loved our stay"
The price is ¥14,075
¥15,921 total
includes taxes & fees
Oct 5 - Oct 6
Drury Plaza Hotel Mt. Vernon

Super 8 by Wyndham Carbondale

2.0 star property
7.4 out of 10, Good, (1008)
"The hotel was very clean & the breakfast was more than enough "
The price is ¥9,673
¥11,122 total
includes taxes & fees
Sep 29 - Sep 30
Super 8 by Wyndham Carbondale

La Quinta Inn & Suites by Wyndham Effingham

3.0 star property
9.2 out of 10, Wonderful, (1011)
"Loved the quietness during our stay. "
The price is ¥14,422
¥16,150 total
includes taxes & fees
Oct 5 - Oct 6
La Quinta Inn & Suites by Wyndham Effingham

Drury Inn & Suites Marion

3.0 star property
9.4 out of 10, Exceptional, (1010)
"We had an excellent stay."
The price is ¥9,672
¥11,605 total
includes taxes & fees
Oct 5 - Oct 6
Drury Inn & Suites Marion

Days Inn & Suites by Wyndham Casey

2.0 star property
7.4 out of 10, Good, (792)
"Clean, nice staff, ok stay"
The price is ¥9,643
¥10,702 total
includes taxes & fees
Sep 28 - Sep 29
Days Inn & Suites by Wyndham Casey

Super 8 by Wyndham Mt. Vernon IL

2.5 star property
7.8 out of 10, Good, (1008)
"Decent hotel. Everything's pretty well kept "
The price is ¥9,701
¥11,066 total
includes taxes & fees
Oct 5 - Oct 6
Super 8 by Wyndham Mt. Vernon IL

Baymont by Wyndham Marion

2.5 star property
8.4 out of 10, Very Good, (1037)
"We stayed overnight for work and were very impressed with the hotel."
The price is ¥12,650
¥15,177 total
includes taxes & fees
Sep 28 - Sep 29
Baymont by Wyndham Marion

Comfort Suites Mount Vernon

2.5 star property
8.8 out of 10, Excellent, (1029)
"Our stay was very good. "
The price is ¥16,323
¥18,416 total
includes taxes & fees
Sep 28 - Sep 29
Comfort Suites Mount Vernon

SureStay Hotel by Best Western Whittington Rend Lake

2.5 star property
8.8 out of 10, Excellent, (863)
"Nice well kept property, breakfast very limited. Great choice to stay"
The price is ¥10,044
¥11,147 total
includes taxes & fees
Oct 5 - Oct 6
SureStay Hotel by Best Western Whittington Rend Lake

Best Western Delta Inn

2.5 star property
9.2 out of 10, Wonderful, (1024)
"Courteous staff, feel safe, clean rooms Thank you"
The price is ¥13,281
¥14,872 total
includes taxes & fees
Oct 5 - Oct 6
Best Western Delta Inn

Seasons Inn & Suites Highland

2.5 star property
8.0 out of 10, Very Good, (619)
"Staff was very accommodating and quick"
Seasons Inn & Suites Highland

Best Western Marion Hotel

2.5 star property
8.2 out of 10, Very Good, (1018)
"Conveniently located for dining, shopping and interstate access."
The price is ¥11,251
¥13,499 total
includes taxes & fees
Sep 28 - Sep 29
Best Western Marion Hotel

Quality Inn Effingham North

2.5 star property
8.4 out of 10, Very Good, (957)
"Clean nice hotel"
The price is ¥12,858
¥14,270 total
includes taxes & fees
Oct 5 - Oct 6
Quality Inn Effingham North

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

2.5 star property
9.4 out of 10, Exceptional, (480)
"Rooms were clean and comfy, great breakfast "
The price is ¥19,198
¥21,306 total
includes taxes & fees
Oct 9 - Oct 10
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Harrah's Metropolis Hotel & Casino

3.5 star property
8.2 out of 10, Very Good, (1009)
"Excellent hotel for the overnight stay "
The price is ¥16,323
¥20,511 total
includes taxes & fees
Sep 29 - Sep 30
Harrah's Metropolis Hotel & Casino

Super 8 by Wyndham Harrisburg

2.0 star property
7.0 out of 10, Good, (513)
"Quit place to stay "
The price is ¥11,980
¥13,295 total
includes taxes & fees
Sep 27 - Sep 28
Super 8 by Wyndham Harrisburg

Days Inn by Wyndham Effingham

2.0 star property
6.0 out of 10, (1002)
"This was a great place to stay "
The price is ¥7,590
¥8,500 total
includes taxes & fees
Sep 28 - Sep 29
Days Inn by Wyndham Effingham

Super 8 by Wyndham Greenville

2.0 star property
8.0 out of 10, Very Good, (736)
"It’s not super fancy, as you’d expect, but the place was decent and seemed clean, the staff was very friendly and helpful, and the prices are decent if you need a quick stay. "
The price is ¥10,101
¥11,210 total
includes taxes & fees
Oct 5 - Oct 6
Super 8 by Wyndham Greenville

Red Lion Inn & Suites Pontoon Beach

2.5 star property
7.8 out of 10, Good, (516)
"Very clean, friendly, delicious breakfast, highly recommended"
The price is ¥10,269
¥11,625 total
includes taxes & fees
Sep 28 - Sep 29
Red Lion Inn & Suites Pontoon Beach
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Southern Illinois, IL

Showing deals for:Oct 3 - Oct 5
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Southern Illinois attractions

Southern Illinois University
Campus Lake at Southern Illinois University in Carbondale, IL.

Southern Illinois University

4.5/5(173 reviews)

Take a campus tour or just explore the area of Southern Illinois University, during your trip to Carbondale. Check out the shops and top-notch restaurants in this family-friendly area.

Scott Air Force Base

Scott Air Force Base

4.5/5(40 reviews)

After visiting Scott Air Force Base, make a plan to see the other sights and activities in Scott Air Force Base. Attend a sporting event in this family-friendly area.

DuQuoin State Fairgrounds

DuQuoin State Fairgrounds

4/5(25 reviews)

Catch an event at DuQuoin State Fairgrounds during your trip to Du Quoin. Experience the area's festivals and live music.

Learn more about Southern Illinois

Discover the culture and history of this region shaped by indigenous and pioneering communities and spend time in its peaceful, picturesque landscapes.

Southern Illinois showing forest scenes, a sunset and landscape views
Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau

Top Southern Illinois Hotel Reviews

More cheap stays in Southern Illinois

More cheap stays in Southern Illinois

Hotels in Southern Illinois with star-rating

Hotels in Southern Illinois with star-rating

Explore a world of travel with Expedia

Explore a world of travel with Expedia