A forested valley with autumn foliage, a rocky cliff, and a sunset.

Find all hotels by La Quinta Inn & Suites in Southern Illinois, IL from ¥13,239

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Check prices for these dates

Tonight
Sep 29 - Sep 30
Tomorrow
Sep 30 - Oct 1
This weekend
Oct 2 - Oct 4
Next weekend
Oct 9 - Oct 11

Our top choices for Southern Illinois La Quinta Inn & Suites

1. La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
Eastport
United States
Lauren
¥14,580
¥16,764 total
includes taxes & fees
Oct 26 - Oct 27
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

2. La Quinta Inn & Suites by Wyndham Effingham

La Quinta Inn & Suites by Wyndham Effingham
Effingham
United States
Alexis
¥17,395
¥19,479 total
includes taxes & fees
Oct 4 - Oct 5
La Quinta Inn & Suites by Wyndham Effingham

3. La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis

La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
O'Fallon
United States
Tahjae
¥11,515
¥13,239 total
includes taxes & fees
Oct 4 - Oct 5
La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis

4. La Quinta Inn & Suites by Wyndham Pontoon Beach

La Quinta Inn & Suites by Wyndham Pontoon Beach
Granite City
United States
Weldon
¥17,158
¥19,729 total
includes taxes & fees
Oct 6 - Oct 7
La Quinta Inn & Suites by Wyndham Pontoon Beach
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Top Southern Illinois Hotel Reviews

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

10/10 Excellent
"Everything was great clean staff was great food was great can’t wait to go back"
Barbara 1-night trip
Posted 4 hours ago
Drury Plaza Hotel Mt. Vernon
Country Inn & Suites by Radisson, Effingham, IL

Country Inn & Suites by Radisson, Effingham, IL

10/10 Excellent
"The staff were kind and helpful with any questions. The room and hotel itself were very clean and comfortable. The only concern I had, was that no maid staff came in and made our beds or gave us fresh towels; even when we didn't have a sign on the door stating for them not to. Other than that, it was a wonderful experience!"
Jamie 1-night trip
Posted 4 hours ago
Country Inn & Suites by Radisson, Effingham, IL
Quality Inn & Suites Metropolis I-24

Quality Inn & Suites Metropolis I-24

8/10 Good
"Motel is close to the interstate and has a bar and grill next door. Staff was very pleasant and helpful. Lobby and room were clean and neat. The hallway to the room had a musty mildew smell to it. Shower pressure was adequate but weak. TV and Air conditioning were both working well."
Paul 1-night trip
Posted 4 hours ago
Quality Inn & Suites Metropolis I-24
Comfort Suites Mount Vernon

Comfort Suites Mount Vernon

8/10 Good
"Finally a room with a walk in shower and grab bars by toilet"
Anjanette 1-night trip
Posted 10 hours ago
Comfort Suites Mount Vernon
Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL

10/10 Excellent
"Fabulous that I arrived & had Happy Hour Meal with Drinks & a great breakfast! Thx! Dennis D."
Dennis 1-night trip
Posted 23 hours ago
Drury Inn & Suites St. Louis O'Fallon, IL
Ramada by Wyndham Effingham

Ramada by Wyndham Effingham

10/10 Excellent
"It is a modest hotel with helpful staff, easily accessible handicapped parking, and surprisingly good scrambled eggs :)"
Noreen 1-night trip
Posted 2 days ago
Ramada by Wyndham Effingham
Baymont by Wyndham Marion

Baymont by Wyndham Marion

8/10 Good
"The only thing that I think would be good to change is to add something so the bath tubs are not so slippery."
Deb 3-night trip
Posted 2 days ago
Baymont by Wyndham Marion
Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis

10/10 Excellent
"Property was well maintained. The room was clean and the bed was comfortable. The shower looked a little worn in some spots but it was fine overall. Room was cool and you could control the temperature. The breakfast was great and a nice touch every morning. Food was fresh and hot. Staff was friendly. We came for family weekend and we would stay again."
Veronica 3-night trip
Posted 2 days ago
Comfort Inn Edwardsville - St. Louis
Walker's Bluff Casino Resort

Walker's Bluff Casino Resort

10/10 Excellent
"The staff were very kind and helpful! The security guard even noticed my trunk was opened and closed it for me. I’ve stayed twice and both times the hotel and room was very clean and staff were friendly and welcoming. My only two complaints would be that the music in the lobby is loud and annoying and that the breakfast isn’t worth the price. But those things won’t keep from staying again when I’m in the area. I think the hotel clerk was Miranda in the evening and she was above and beyond friendly!"
Amber 1-night trip
Posted 2 days ago
Walker's Bluff Casino Resort

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