A forested valley with autumn foliage, a rocky cliff, and a sunset.

Find all hotels by La Quinta Inn & Suites in Southern Illinois, IL from ¥12,805

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Check prices for these dates

Tonight
Sep 15 - Sep 16
Tomorrow
Sep 16 - Sep 17
This weekend
Sep 18 - Sep 20
Next weekend
Sep 25 - Sep 27

Our top choices for Southern Illinois La Quinta Inn & Suites

1. La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
Eastport
United States
Gireesh Kumar
¥13,896
¥15,978 total
includes taxes & fees
Oct 12 - Oct 13
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

2. La Quinta Inn & Suites by Wyndham Effingham

La Quinta Inn & Suites by Wyndham Effingham
Effingham
United States
Alexis
¥17,571
¥19,676 total
includes taxes & fees
Sep 20 - Sep 21
La Quinta Inn & Suites by Wyndham Effingham

3. La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis

La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
O'Fallon
United States
Tahjae
¥11,137
¥12,805 total
includes taxes & fees
Sep 17 - Sep 18
La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis

4. La Quinta Inn & Suites by Wyndham Pontoon Beach

La Quinta Inn & Suites by Wyndham Pontoon Beach
Granite City
United States
Weldon
¥16,743
¥19,251 total
includes taxes & fees
Sep 22 - Sep 23
La Quinta Inn & Suites by Wyndham Pontoon Beach
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Top Southern Illinois Hotel Reviews

Ramada by Wyndham Effingham

Ramada by Wyndham Effingham

8/10 Good
"Breakfast not even hot tea"
Rhonda 1-night trip
Posted 1 hour ago
Ramada by Wyndham Effingham
Quality Inn O'Fallon - St. Louis - Shiloh

Quality Inn O'Fallon - St. Louis - Shiloh

8/10 Good
"Nice people but it’s been almost 2 weeks since a refund was supposed to reach my account already but still has not. Supposedly released on Sept. 3rd the day we spoke face to face but have yet to receive refund on a room and security deposit. Don’t like that every time I call their number then click option 2 the phone always hangs up no matter the day or time. Please if anyone at the hotel working there can see this review please try to reach out to me so we can resolve this or know what’s going on."
Maximiliano 4-night trip
Posted 5 hours ago
Quality Inn O'Fallon - St. Louis - Shiloh
Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis

10/10 Excellent
"Great property that met all my expectations and had very kind staff."
Scarlett 1-night trip
Posted 8 hours ago
Comfort Inn Edwardsville - St. Louis
Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

10/10 Excellent
"G"
Candy 1-night trip
Posted 9 hours ago
Drury Plaza Hotel Mt. Vernon
Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL

10/10 Excellent
"Room was nicely decorated and clean, bed and pillows very comfortable, staff friendly and helpful, breakfast was delicious. Only downside was air conditioning loud with a scratching sound with blower"
NANCY 1-night trip
Posted 23 hours ago
Drury Inn & Suites St. Louis O'Fallon, IL
Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

10/10 Excellent
"The amenities where excellent and offered more then other places offer. The staff were kind d and friendly. The rooms where clean, comfortable, and up to what you wa t feom a hotel stay.I would stay there again."
Janet 6-night trip
Posted 2 days ago
Drury Inn & Suites St. Louis Fairview Heights
Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination

Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination

10/10 Excellent
"I enjoyed my stay at Harrahs. The hotel was nice and clean. The staff was friendly and helpful. I ordered room service food from the grill which arrived quickly and tasted fresh. The only thing I was wondering was why The Bridges didn't have room service. I did go to Bridges for breakfast and it tasted fresh and flavorful. I enjoyed the casino with had a good selection of slots, but I would stay there even without gaming. I enjoyed it very much."
Alisa 1-night trip
Posted 3 days ago
Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination
Comfort Suites Fairview Heights - St. Louis

Comfort Suites Fairview Heights - St. Louis

8/10 Good
"There was a smell in our room that was very strong. Other than that it was clean."
Stacey 1-night trip
Posted 4 days ago
Comfort Suites Fairview Heights - St. Louis

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