A forested valley with autumn foliage, a rocky cliff, and a sunset.

Find all hotels by La Quinta Inn & Suites in Southern Illinois, IL from ¥12,877

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Check prices for these dates

Tonight
Sep 16 - Sep 17
Tomorrow
Sep 17 - Sep 18
This weekend
Sep 18 - Sep 20
Next weekend
Sep 25 - Sep 27

Our top choices for Southern Illinois La Quinta Inn & Suites

1. La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
Eastport
United States
Gireesh Kumar
¥13,636
¥15,678 total
includes taxes & fees
Sep 27 - Sep 28
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

2. La Quinta Inn & Suites by Wyndham Effingham

La Quinta Inn & Suites by Wyndham Effingham
Effingham
United States
Alexis
¥17,406
¥19,492 total
includes taxes & fees
Sep 20 - Sep 21
La Quinta Inn & Suites by Wyndham Effingham

3. La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis

La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
O'Fallon
United States
Tahjae
¥11,200
¥12,877 total
includes taxes & fees
Sep 17 - Sep 18
La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis

4. La Quinta Inn & Suites by Wyndham Pontoon Beach

La Quinta Inn & Suites by Wyndham Pontoon Beach
Granite City
United States
Weldon
¥16,813
¥19,332 total
includes taxes & fees
Sep 22 - Sep 23
La Quinta Inn & Suites by Wyndham Pontoon Beach
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Top Southern Illinois Hotel Reviews

Drury Inn & Suites Marion

Drury Inn & Suites Marion

10/10 Excellent
"Clean room, staff was great, breakfast was wonderful. Hot tub was large and"
Holly 2-night trip
Posted 1 hour ago
Drury Inn & Suites Marion
Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL

10/10 Excellent
"This was my first stay. Staff were super friendly, rooms and common areas clean. Even with roof replacement going on, we couldn't even tell. Definitely will keep Drury on our short list of places when we need to stay in hotel"
Charlene 2-night trip
Posted 2 hours ago
Drury Inn & Suites St. Louis O'Fallon, IL
Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

8/10 Good
"Good"
Mark 1-night trip
Posted 5 hours ago
Drury Plaza Hotel Mt. Vernon
Comfort Suites Mount Vernon

Comfort Suites Mount Vernon

10/10 Excellent
"Very nice new/updated hotel. Good breakfast. Sausage gravy both days we were there. It’s a good location with several restaurants walkable. The BBQ place across the street was great. My only complaint is the room air conditioning was very loud and had a rattling sound. It kept my wife and me up during the night."
Gregory 2-night trip
Posted 21 hours ago
Comfort Suites Mount Vernon
Ramada by Wyndham Effingham

Ramada by Wyndham Effingham

8/10 Good
"Breakfast not even hot tea"
Rhonda 1-night trip
Posted 1 day ago
Ramada by Wyndham Effingham
Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis

10/10 Excellent
"Great property that met all my expectations and had very kind staff."
Scarlett 1-night trip
Posted 1 day ago
Comfort Inn Edwardsville - St. Louis
Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

10/10 Excellent
"The amenities where excellent and offered more then other places offer. The staff were kind d and friendly. The rooms where clean, comfortable, and up to what you wa t feom a hotel stay.I would stay there again."
Janet 6-night trip
Posted 3 days ago
Drury Inn & Suites St. Louis Fairview Heights
Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination

Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination

10/10 Excellent
"I enjoyed my stay at Harrahs. The hotel was nice and clean. The staff was friendly and helpful. I ordered room service food from the grill which arrived quickly and tasted fresh. The only thing I was wondering was why The Bridges didn't have room service. I did go to Bridges for breakfast and it tasted fresh and flavorful. I enjoyed the casino with had a good selection of slots, but I would stay there even without gaming. I enjoyed it very much."
Alisa 1-night trip
Posted 4 days ago
Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination

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