Photo by Southernmost Illinois Tourism Bureau

Find hotels in Southwest Illinois, IL from ¥8,848

Start date: Check-in selected.
To Date
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Compare 712 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Our top choices for Southwest Illinois hotels

The Principal Hotel

3.5 star property
9.8 out of 10, Exceptional, (141)
"Loved the history, clean rooms, excellent service, professional staff, Will be back."
The price is ¥15,322
¥17,004 total
includes taxes & fees
Oct 2 - Oct 3
The Principal Hotel

Drury Plaza Hotel Mt. Vernon

3.0 star property
9.6 out of 10, Exceptional, (1466)
"Loved our stay"
The price is ¥14,021
¥15,856 total
includes taxes & fees
Sep 28 - Sep 29
Drury Plaza Hotel Mt. Vernon

Drury Inn & Suites St. Louis Collinsville

3.0 star property
9.6 out of 10, Exceptional, (1010)
"Had a great stay! Will stay again. "
The price is ¥15,498
¥17,820 total
includes taxes & fees
Oct 19 - Oct 20
Drury Inn & Suites St. Louis Collinsville

Drury Inn & Suites St. Louis O'Fallon, IL

3.0 star property
9.6 out of 10, Exceptional, (1009)
"Clean, friendly staff, easy check in, comfortable bed, great breakfast, close to airport "
The price is ¥15,055
¥17,461 total
includes taxes & fees
Oct 5 - Oct 6
Drury Inn & Suites St. Louis O'Fallon, IL

Best Western Plus Centralia Hotel & Suites

2.5 star property
9.6 out of 10, Exceptional, (577)
"A good hotel. We always stay there when we travel to centralia to visit family "
The price is ¥20,518
¥22,976 total
includes taxes & fees
Sep 28 - Sep 29
Best Western Plus Centralia Hotel & Suites

Holiday Inn Express Troy by IHG

2.5 star property
9.4 out of 10, Exceptional, (660)
"The staff was friendly and helpful and the continental breakfast was fantastic."
The price is ¥19,485
¥21,624 total
includes taxes & fees
Oct 12 - Oct 13
Holiday Inn Express Troy by IHG

Drury Inn & Suites Marion

3.0 star property
9.4 out of 10, Exceptional, (1009)
"We had an excellent stay."
The price is ¥13,874
¥16,646 total
includes taxes & fees
Oct 12 - Oct 13
Drury Inn & Suites Marion

Walker's Bluff Casino Resort

4.5 star property
9.4 out of 10, Exceptional, (374)
"Very nice room, nice scenery not an interstate running thru it"
Walker's Bluff Casino Resort

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

2.5 star property
9.4 out of 10, Exceptional, (480)
"Rooms were clean and comfy, great breakfast "
The price is ¥19,042
¥21,133 total
includes taxes & fees
Oct 8 - Oct 9
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Drury Inn & Suites St. Louis Fairview Heights

3.0 star property
9.2 out of 10, Wonderful, (1020)
"A very comfortable stay!"
The price is ¥13,800
¥15,591 total
includes taxes & fees
Sep 29 - Sep 30
Drury Inn & Suites St. Louis Fairview Heights

Comfort Inn & Suites Marion I-57

2.5 star property
9.2 out of 10, Wonderful, (1007)
"Wonderful place to stay!"
The price is ¥15,942
¥19,128 total
includes taxes & fees
Oct 12 - Oct 13
Comfort Inn & Suites Marion I-57

Holiday Inn Express & Suites Edwardsville by IHG

2.5 star property
9.2 out of 10, Wonderful, (781)
"Probably one of the best Holiday Inn & Suites we’ve ever stayed at. Very clean, suite was huge, updated, pillows were awesome… no complaints! Would definitely stay here again. "
The price is ¥21,551
¥24,779 total
includes taxes & fees
Oct 5 - Oct 6
Holiday Inn Express & Suites Edwardsville by IHG

Hampton Inn O'Fallon

2.5 star property
9.2 out of 10, Wonderful, (784)
"Nice hotel. Clean. Spacious."
The price is ¥16,813
¥19,499 total
includes taxes & fees
Oct 5 - Oct 6
Hampton Inn O'Fallon

Best Western Plus MidAmerica Hotel

2.5 star property
9.0 out of 10, Wonderful, (1006)
"Staff was very helpful..military discount.. Clean rooms and breakfast lounge.."
The price is ¥16,538
¥18,354 total
includes taxes & fees
Sep 28 - Sep 29
Best Western Plus MidAmerica Hotel

TownePlace Suites by Marriott St. Louis O'Fallon

3.0 star property
9.0 out of 10, Wonderful, (125)
"Stayed 4th of July weekend and was very accommodating of our baseball team. "
The price is ¥17,861
¥20,715 total
includes taxes & fees
Oct 19 - Oct 20
TownePlace Suites by Marriott St. Louis O'Fallon

Holiday Inn Express & Suites Mount Vernon by IHG

2.5 star property
9.0 out of 10, Wonderful, (1011)
"Convenient area and friendly staff "
The price is ¥16,237
¥18,315 total
includes taxes & fees
Oct 5 - Oct 6
Holiday Inn Express & Suites Mount Vernon by IHG

Holiday Inn Express Hotel & Suites Marion Northeast by IHG

2.5 star property
9.0 out of 10, Wonderful, (911)
"Newly remodeled looked very nice"
The price is ¥16,828
¥20,189 total
includes taxes & fees
Oct 12 - Oct 13
Holiday Inn Express Hotel & Suites Marion Northeast by IHG

Red Bud Country Inn

2.5 star property
9.0 out of 10, Wonderful, (46)
"Nice staff, very clean, easy parking. "
The price is ¥13,144
¥14,587 total
includes taxes & fees
Oct 7 - Oct 8
Red Bud Country Inn

SureStay Hotel by Best Western Whittington Rend Lake

2.5 star property
8.8 out of 10, Excellent, (863)
"Nice well kept property, breakfast very limited. Great choice to stay"
The price is ¥9,962
¥11,055 total
includes taxes & fees
Oct 1 - Oct 2
SureStay Hotel by Best Western Whittington Rend Lake

Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake

2.5 star property
8.8 out of 10, Excellent, (670)
"Great place to stay"
The price is ¥14,802
¥16,722 total
includes taxes & fees
Oct 18 - Oct 19
Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Southwest Illinois, IL

Showing deals for:Oct 3 - Oct 5
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Southwest Illinois attractions

Learn more about Southwest Illinois

Explore a “natural city” of trees, enjoy incredible hilltop views, marvel at geological wonders and hop between small towns in this beautiful region.

Southern Illinois which includes a lake or waterhole and forests
Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau

Top Southwest Illinois Hotel Reviews

More cheap stays in Southwest Illinois

More cheap stays in Southwest Illinois

Hotels in Southwest Illinois with star-rating

Hotels in Southwest Illinois with star-rating

Explore a world of travel with Expedia

Explore a world of travel with Expedia