Our top choices for Southern Arizona hotels

Hampton Inn & Suites Tucson Marana

Tucson

Erin

￥28,820 total

includes taxes & fees

Mar 22 - Mar 23

Holiday Inn Express & Suites Nogales by IHG

Nogales

Deborah

￥20,811 total

includes taxes & fees

Feb 26 - Feb 27

Best Western Sonora Inn & Suites

Nogales

Scott

￥18,156 total

includes taxes & fees

Feb 26 - Feb 27

Hampton Inn Tucson-Airport

Tucson Airport Authority

Sallie

￥20,707 total

includes taxes & fees

Mar 1 - Mar 2

Americas Choice Inn And Suites

Gila Bend

Herendira

Casino Del Sol Resort

Drexel Heights

Rebekkah

￥22,003 total

includes taxes & fees

Mar 8 - Mar 9

Comfort Inn Benson near Kartchner Caverns

Benson

Robin

￥20,465 total

includes taxes & fees

Mar 25 - Mar 26

La Quinta Inn & Suites by Wyndham NW Tucson Marana

Cortaro

Dean

￥19,606 total

includes taxes & fees

Mar 8 - Mar 9

Desert Diamond Casino & Hotel

Tucson

Jean

￥22,922 total

includes taxes & fees

Mar 3 - Mar 4

Comfort Suites At Tucson Mall

Tucson

Fallon

￥26,329 total

includes taxes & fees

Mar 9 - Mar 10

Hampton Inn & Suites Tucson Tech Park

Tucson

Harlan

￥27,546 total

includes taxes & fees

Mar 1 - Mar 2

3 Palms Tucson North Foothills

Casas Adobes

Jesse

￥12,967 total

includes taxes & fees

Feb 23 - Feb 24

Hotel Americana

Nogales

George

￥16,938 total

includes taxes & fees

Feb 27 - Feb 28

Estrella at Casino Del Sol

Drexel Heights

Darryl

￥19,463 total

includes taxes & fees

Mar 8 - Mar 9

Premium Suite, 1 Bedroom, Non Smoking | Premium bedding, down comforters, desk, blackout drapes

Country Inn & Suites by Radisson, Tucson Airport, AZ

Tucson Airport Authority

Michael

￥20,791 total

includes taxes & fees

Mar 1 - Mar 2

Suite, 1 King Bed, Non Smoking | Terrace/patio

Canoa Ranch Golf Resort

Canoa Ranch

Yetty

￥26,706 total

includes taxes & fees

Mar 2 - Mar 3

Tombstone Grand Hotel, a Baymont by Wyndham

Tombstone

Kayla

￥17,210 total

includes taxes & fees

Mar 1 - Mar 2

La Quinta Inn & Suites by Wyndham Maricopa - Copper Sky

Maricopa

Kelly

￥28,047 total

includes taxes & fees

Mar 9 - Mar 10

Sonoran Desert Inn & Conference Center

Ajo

Deena

￥25,192 total

includes taxes & fees

Feb 23 - Feb 24

Inn History Tombstone

Tombstone

James

￥17,905 total

includes taxes & fees

Feb 23 - Feb 24

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Vacation Rentals in Southern Arizona

Apartment

Bisbee Brownstone Suites

Bisbee

"Amazing spacious suite, excellent central location for the festival."

Apartment

Centrally Located Yuma Retreat w/ Fenced Patio

Yuma

"We didn't do much cooking but it was so wonderful to have a full kitchen! Not something you get with a hotel room. All the amenities of home! Very comfortable and convenient location in Yuma. "

Cabin

Boho hip bungalow in Old Bisbee

Bisbee

"The place was really nice, clean and great location. We had a great time, we will definitely be back....."

Aparthotel

Ventana Canyon Club and Lodge

Catalina Foothills

"Excellent place to stay. Great rooms, staff are very friendly. Food is tasty. I did not want to leave!"

Vacation Home

Luminous Sunrise Home with Pool and BBQ

Casa Grande

"Thank you so much for an incredible stay! The pool and hot tub right out front gave us such a unique and relaxing experience, and we loved having the BBQ grill to enjoy evenings outside. Plenty of great parking, super quiet, and felt completely safe the entire time. Your team was wonderful – we can’t wait to come back!"

Apartment

Lower East side NYC in Old Bisbee

Bisbee

"Kevin and Grechen’s place was filled with fun art and memorabilia. The location was awesome. The heater was a bit loud during the night but that is my only complaint. "

Vacation Home

Dreamlight Modern Home with Pool and BBQ

Casa Grande

"Nice place. Would stay here again "

Vacation Home

Sunny Contemporary Home with Pool BBQ

Casa Grande

"Great place to stay and secure."

Cottage

Sunny Tucson Abode w/ Fire Pit 9 Mi to U of A

Stella Mann

"The host was very receptive to what I needed in a timely manner!"

Cottage

Tucson Home w/ Patio & Games < 1 Mi to Park Place

Tucson

"Beautiful, clean home.. just like the pics in real life! Great host."

Cottage

Bisbee Home: Fantastic Views & Walkable Location!

Bisbee

"Perfectly suited for Bisbee. Appointed with everything you need, but you will need to ascend stairs and walk uphill to get there. Not recommended for anyone with mobility issues, but most of Bisbee is accessed by stairs or walking! If you want a true Bisbee experience, and want the comfort and freedom of your own kitchen, this is a great choice!"

Apartment

Single-story Eloy Apartment w/ Patio Space!

Eloy

"Desert Rose is such a beautiful peaceful place to stay! The living quarters are built in a square around a landscaped courtyard with shade trees, l lovely flowers and fountains. We enjoyed sitting out here on our back patio each morning! We will definitely return on our next trip to AZ!!"

Cottage

Lovely Tucson Home ~ Walk to Reid Park Zoo!

Midtown

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Stay near popular Southern Arizona attractions

Saguaro National Park

4.6/5 (2,157 reviews)

Hike, bike or drive through fields and forests containing one of the most recognized cactus plants in the world.

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Pima Air and Space Museum

4.4/5 (902 reviews)

One of the largest aviation museums in the world houses aircraft and spacecraft from the 1920s to the present.

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Learn more about Southern Arizona

The iconic, cactus-lined deserts of Southern Arizona hark back to the days of the Old West, while the rest of the region offers trendy cities and lush vineyards.

See all hotels in Southern Arizona

Saguaro National Park featuring desert views and a sunset

Top Southern Arizona Hotel Reviews

Ramada by Wyndham Viscount Suites Tucson East

10/10 Excellent

"The room was clean, a bit run down, but not bad by any means. The staff was friendly and efficient. The breakfast was substantial and a good variety was offered daily. "

3 Palms Tucson North Foothills

10/10 Excellent

"It’s an amazing spot to stay. The staff is accommodating and pleasant. The rooms are very reasonably priced and the layouts and decor make it feel spacious and like you’re actually in a room vs a lifeless cubicle. I like the separation between living space and bedroom. Pillows are comfortable and appropriate size vs a small deteriorating piece of fluff. "