Mission Bay, CA

San Francisco

A coastal cityscape with a large body of water, several ships, and ongoing construction on a prominent red building.
A coastal cityscape with a prominent skyscraper, a large stadium, and a marina with boats.
A cityscape at dusk with a parking lot and buildings.
A large reflective sphere in front of a modern building with a glass facade and a Christmas tree.

Stay near popular Mission Bay attractions

Chase Center

8.8/10 (1,176 reviews)
Catch an event at Chase Center during your trip to San Francisco. Amble around this vibrant area's Chinatown or experience its fascinating museums.
See properties

Things to do

Inside the cell block at Alcatraz

Alcatraz ticket with free round trip ferry & App Audio Packages

￥13,768
per adult
94% of travellers recommend
Alcatraz ticket with free round trip ferry & App Audio Packages
California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

￥7,844
per adult
86% of travellers recommend
California Academy of Sciences Daytime Admission
Aquarium of the Bay General Admission Ticket

San Francisco, Aquarium of the Bay General Admission Ticket

￥4,603
per adult
100% of travellers recommend
San Francisco, Aquarium of the Bay General Admission Ticket
Bridge 2 Bridge Tour: Golden Gate Bridge to Bay Bridge

San Francisco Bridge to Bridge Cruise (90-minutes)

￥7,684
per adult
94% of travellers recommend
San Francisco Bridge to Bridge Cruise (90-minutes)
San Francisco SkyStar Wheel - Private Gondolas

San Francisco SkyStar Wheel - Private Gondolas

￥3,006
per adult
82% of travellers recommend
San Francisco SkyStar Wheel - Private Gondolas
de Young Museum General Admission Ticket

de Young Museum General Admission Ticket

￥4,002
per adult
88% of travellers recommend
de Young Museum General Admission Ticket
See all activities in San Francisco

Mission Bay Hotel Deals

LUMA Hotel San Francisco

LUMA Hotel San Francisco

4 out of 5
100 Channel Street San Francisco CA
The price is ￥34,528 per night from Sep 20 to Sep 21
￥34,528
￥40,638 total
Sep 20 - Sep 21
includes taxes & fees
Stay at this hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our ...
9.6/10 Exceptional! (2,614 reviews)
"Everything was great. Central located for everything I needed."

Reviewed on Sep 15, 2026

LUMA Hotel San Francisco
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
The price is ￥26,240 per night from Sep 20 to Sep 21
￥26,240
￥30,883 total
Sep 20 - Sep 21
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
Holiday Inn Golden Gateway by IHG
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
The price is ￥24,887 per night from Sep 24 to Sep 25
￥24,887
￥35,682 total
Sep 24 - Sep 25
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast ...
9/10 Wonderful! (7,659 reviews)
"Breakfast was excellent but room had smell and noise on ac unit."

Reviewed on Sep 16, 2026

Hotel Riu Plaza Fisherman's Wharf
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St San Francisco CA
The price is ￥21,745 per night from Oct 16 to Oct 17
￥21,745
￥25,593 total
Oct 16 - Oct 17
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a fitness center, and valet parking (surcharge). Our guests praise the pool and ...
Handlery Union Square Hotel
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
The price is ￥23,114 per night from Sep 18 to Sep 19
￥23,114
￥27,204 total
Sep 18 - Sep 19
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...
Hilton San Francisco Financial District
Chancellor Hotel on Union Square

Chancellor Hotel on Union Square

3.5 out of 5
433 Powell St San Francisco CA
The price is ￥22,215 per night from Sep 20 to Sep 21
￥22,215
￥26,180 total
Sep 20 - Sep 21
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff ...
9.4/10 Exceptional! (3,456 reviews)
"The hotel is in an excellent location just a few steps from Union Square, the cable car stop, and the BART train station, not to mention all the clothing stores and food options around it. The room was clean and very comfortable with a refrigerator inside, and I really liked the free cookies, apples, ..."

Reviewed on Sep 16, 2026

Chancellor Hotel on Union Square
See all 4,423 properties in Mission Bay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Mission Bay

Find the best Mission Bay areas and neighborhoods for the activities you enjoy most. Learn more about Mission Bay
Learn more about Mission Bay
A street with shops, including a crystal shop and a crepes cafe.

Fisherman's Wharf

Pier 39 and San Francisco Bay are top sights in Fisherman's Wharf, and you should be sure to explore the popular shops. Hop aboard the metro at Jones St and Beach St Stop or Jefferson St & Taylor St Stop to see more sights in the area.

A cityscape with tall buildings, a central plaza with palm trees, and a flag on one of the buildings.

Union Square

Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city.

A trolley on a street with buildings and a clock tower.

Downtown San Francisco

Known for its fascinating museums, popular shops, and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and San Francisco Bay are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

A cityscape with modern skyscrapers, a central park with pathways, and a few people walking.

South of Market

Oracle Park and San Francisco Bay are top sights in South of Market, and you should be sure to explore the popular shops. Hop aboard the metro at Yerba Buena-Moscone Station or Fourth-Brannan Station to see more sights in the area.

A street lined with historic buildings, parked cars, and a clear blue sky.

Nob Hill

Travelers love Nob Hill for its popular shops, and you can see more of San Francisco by jumping on the metro at Washington St & Leavenworth St Stop or Washington St & Jones St Stop. You might spend time checking out top sights like SF Masonic Auditorium and Cable Car Museum.

Mission Bay, CA

Explore a world of travel with Expedia