
Panama City Vacations
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Where to stay in Panama City
Find the best Panama City areas and neighborhoods for the activities you enjoy most. Learn more about Panama City

Casco Viejo
4.5/5(178 area reviews)
Unique features of Casco Viejo include the historic sites and bars. Make a stop by Interoceanic Canal Museum or National Theater while you're exploring the area.
Find the Best Panama City Vacation Packages
Panama City Hotel Deals

Hotel Riu Plaza Panama
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is ¥18,118 per night from Sep 21 to Sep 22
¥18,118
¥19,930 total
Sep 21 - Sep 22
includes taxes & fees
9/10 Wonderful! (4,282 reviews)
"Enjoyed the stay here. More quiet than other RIU locations I've been to"
Reviewed on Sep 19, 2025

Waymore Hotel Spa & Casino
Calle Augusto Samuel Boyd y Calle Eusebi, Panama City
Fully refundableReserve now, pay when you stay
The price is ¥13,316 per night from Sep 21 to Sep 22
¥13,316
¥14,648 total
Sep 21 - Sep 22
includes taxes & fees
9/10 Wonderful! (487 reviews)
1st solo trip- nailed it!!
"This was an awesome trip! The hotel was well worth the $$. The people were nice and the area was great! I will be back!!!"
Reviewed on Sep 17, 2025

Sheraton Grand Panama
Via Israel And 77th Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is ¥19,840 per night from Sep 26 to Sep 27
¥19,840
¥21,824 total
Sep 26 - Sep 27
includes taxes & fees
8.4/10 Very Good! (949 reviews)
"My favorite things were the Bakery, a restaurant and a Casino on property."
Reviewed on Sep 14, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Panama City

Avenida Balboa
You can find the perfect gifts to bring home at Avenida Balboa during your trip to Panama City. While you're in the area, wander around the natural setting.

Panama Canal Railway
Enjoy an outing to Panama Canal Railway during your stay in Ancon. Stroll along the seaside or visit the shops in this culturally rich area.
Albrook Shopping Mall
You can enjoy some retail therapy with a trip to Albrook Shopping Mall, a favorite shopping spot in Ancon. Amble around this culturally rich area's seaside and enjoy its top-notch restaurants.
What to do in Panama City

Day Tour in San Blas Islands All Included Visiting 4 Islands
¥22,121
per adult
94% of travellers recommend

Panama City Visit an Indian town Embera and waterfall with lunch
¥7,423
per adult
94% of travellers recommend
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