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Dec 13 - Dec 14
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Dec 14 - Dec 15
Next weekend
Dec 19 - Dec 21
In two weeks
Dec 26 - Dec 28

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Our top choices for Greenville hotels

Standard Room, 2 Queen Beds | Desk, iron/ironing board, free cribs/infant beds, rollaway beds
Super 8 by Wyndham Greenville

Super 8 by Wyndham Greenville

Super 8 by Wyndham Greenville
2.0 star property
Greenville
8.0 out of 10, Very Good, (757)
"A good breakfast, clean and tidy. I felt like I was at home."
United States
Olesia
The price is ￥10,340
￥11,475 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Super 8 by Wyndham Greenville
Desk, blackout drapes, iron/ironing board, free WiFi
Comfort Inn & Suites Greenville I-70

Comfort Inn & Suites Greenville I-70

Comfort Inn & Suites Greenville I-70
2.5 star property
Greenville
8.4 out of 10, Very Good, (415)
"Room was clean and comfortable."
United States
Michael
The price is ￥14,124
￥15,674 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Comfort Inn & Suites Greenville I-70
Desk, laptop workspace, iron/ironing board, bed sheets
SureStay Hotel by Best Western Greenville

SureStay Hotel by Best Western Greenville

SureStay Hotel by Best Western Greenville
2.5 star property
Greenville
7.6 out of 10, Good, (559)
"A great place to stay"
United States
Eileen
The price is ￥9,578
￥10,630 total
includes taxes & fees
Dec 14 - Dec 15
SureStay Hotel by Best Western Greenville
Desk, free WiFi
Budget Inn- Greenville

Budget Inn- Greenville

Budget Inn- Greenville
2.0 star property
Greenville
6.6 out of 10, (165)
"The hotel is a great value and good location. "
United States
Michael
The price is ￥7,697
￥8,543 total
includes taxes & fees
Dec 21 - Dec 22
Budget Inn- Greenville
Restaurant
Baymont by Wyndham Litchfield

Baymont by Wyndham Litchfield

Baymont by Wyndham Litchfield
2.5 star property
Litchfield
8.4 out of 10, Very Good, (1000)
"Staff was friendly and the room was clean and tidy. "
United States
Kasey
The price is ￥15,394
￥16,930 total
includes taxes & fees
Dec 16 - Dec 17
Baymont by Wyndham Litchfield
Reception
Best Western Plus Centralia Hotel & Suites

Best Western Plus Centralia Hotel & Suites

Best Western Plus Centralia Hotel & Suites
2.5 star property
Centralia
9.6 out of 10, Exceptional, (600)
"Very beautiful place to stay "
United States
Valerie
The price is ￥18,752
￥20,998 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Best Western Plus Centralia Hotel & Suites
Seasonal outdoor pool, pool umbrellas, sun loungers
Quality Inn & Suites Vandalia near I-70 and Hwy 51

Quality Inn & Suites Vandalia near I-70 and Hwy 51

Quality Inn & Suites Vandalia near I-70 and Hwy 51
2.5 star property
Vandalia
8.4 out of 10, Very Good, (1001)
"Awesome place to stay. Clean room, comfortable bed, amenities were accommodating, plenty of restaurants near by to choose from, and near the highway."
United States
Evelyn
The price is ￥10,572
￥11,522 total
includes taxes & fees
Dec 14 - Dec 15
Quality Inn & Suites Vandalia near I-70 and Hwy 51
Exterior
Holiday Inn Express & Suites Litchfield West by IHG

Holiday Inn Express & Suites Litchfield West by IHG

Holiday Inn Express & Suites Litchfield West by IHG
2.5 star property
Litchfield
9.6 out of 10, Exceptional, (574)
"Clean room, great shower, excellent breakfast."
United States
Nancy
The price is ￥20,369
￥22,402 total
includes taxes & fees
Dec 24 - Dec 25
Holiday Inn Express & Suites Litchfield West by IHG
Free daily full breakfast
Holiday Inn Express & Suites Vandalia by IHG

Holiday Inn Express & Suites Vandalia by IHG

Holiday Inn Express & Suites Vandalia by IHG
2.5 star property
Vandalia
8.8 out of 10, Excellent, (771)
"Room is great. Check in person was very welcoming "
United States
walter
The price is ￥16,360
￥17,830 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Holiday Inn Express & Suites Vandalia by IHG
Lobby
Ramada by Wyndham Vandalia

Ramada by Wyndham Vandalia

Ramada by Wyndham Vandalia
2.0 star property
Vandalia
7.8 out of 10, Good, (808)
"Staffing was awesome and helpful. "
United States
Warren
The price is ￥10,573
￥11,522 total
includes taxes & fees
Dec 15 - Dec 16
Ramada by Wyndham Vandalia
Desk, laptop workspace, blackout drapes, iron/ironing board
Quality Inn Litchfield Route 66

Quality Inn Litchfield Route 66

Quality Inn Litchfield Route 66
2.5 star property
Litchfield
8.6 out of 10, Excellent, (591)
"Great value for the money"
United States
Lori
The price is ￥14,616
￥16,074 total
includes taxes & fees
Dec 16 - Dec 17
Quality Inn Litchfield Route 66
Free daily continental breakfast
Super 8 by Wyndham Staunton

Super 8 by Wyndham Staunton

Super 8 by Wyndham Staunton
2.0 star property
Staunton
8.6 out of 10, Excellent, (765)
"Both great"
United States
Pam
The price is ￥10,992
￥12,199 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Super 8 by Wyndham Staunton
Reception
Americas Best Value Inn Vandalia

Americas Best Value Inn Vandalia

Americas Best Value Inn Vandalia
2.0 star property
Vandalia
7.8 out of 10, Good, (191)
"It was definitely what we needed after a long day on the road"
United States
Jeremy
The price is ￥7,550
￥8,227 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Americas Best Value Inn Vandalia
Exterior
Motel 6 Litchfield, IL

Motel 6 Litchfield, IL

Motel 6 Litchfield, IL
2.0 star property
Litchfield
7.2 out of 10, Good, (153)
"The room was very clean and the staff was very helpful "
United States
Susan
The price is ￥8,617
￥9,477 total
includes taxes & fees
Dec 26 - Dec 27
Motel 6 Litchfield, IL
Porch
Historic Red Rooster Inn

Historic Red Rooster Inn

Historic Red Rooster Inn
2.0 star property
Hillsboro
9.8 out of 10, Exceptional, (28)
"Very nicely renovated historic hotel, great brew pub."
United States
Donald
The price is ￥17,331
￥18,367 total
includes taxes & fees
Dec 14 - Dec 15
Historic Red Rooster Inn
Front of property
Lighthouse Lodge

Lighthouse Lodge

Lighthouse Lodge
2.0 star property
Pocahontas
8.8 out of 10, Excellent, (22)
"Excellent breakfast across the street at Funderburk’s!"
United States
Gary
The price is ￥10,914
￥12,344 total
includes taxes & fees
Dec 14 - Dec 15
Lighthouse Lodge
Classic Room, 1 King Bed | Desk, free WiFi, bed sheets
Powhatan Motel

Powhatan Motel

Powhatan Motel
2.5 star property
Pocahontas
8.6 out of 10, Excellent, (192)
"Clean, updated bathroom, easy parking, great breakfast."
United States
Cheryl
The price is ￥15,044
￥15,944 total
includes taxes & fees
Dec 14 - Dec 15
Powhatan Motel
Desk, blackout drapes, iron/ironing board, free cribs/infant beds
Hampton Inn by Hilton Litchfield

Hampton Inn by Hilton Litchfield

Hampton Inn by Hilton Litchfield
2.5 star property
Litchfield
9.0 out of 10, Wonderful, (625)
"Was a nice place to stay for a weekend get a way"
United States
Katrina
The price is ￥15,456
￥16,999 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hampton Inn by Hilton Litchfield
Reception
Americas Best Value Inn Litchfield

Americas Best Value Inn Litchfield

Americas Best Value Inn Litchfield
1.5 star property
Litchfield
5.4 out of 10, (271)
"the motel was very clean for the age; it is an older place the staff was very nice bed was very comfortable."
United States
Arthur
The price is ￥7,930
￥8,721 total
includes taxes & fees
Dec 18 - Dec 19
Americas Best Value Inn Litchfield
Room, 1 Queen Bed, Non Smoking, Kitchenette | Private kitchen | Mini-fridge, microwave
Countryside Inn

Countryside Inn

Countryside Inn
2.0 star property
Hillsboro
5.6 out of 10, (38)
"The property was very well kept and the inside was clean."
United States
Kai-Lyn
The price is ￥12,276
￥13,501 total
includes taxes & fees
Dec 24 - Dec 25
Countryside Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Greenville attractions

Patriot's Park

4.1/5 (9 reviews)
You can take time to visit Patriot's Park during your travels to Greenville. Wander the parks in this family-friendly area.
See properties

Greenville Country Club

3.6/5 (8 reviews)
Enjoy a round of golf in Greenville at Greenville Country Club. You'll find more to see and do in this family-friendly area.
See properties

Learn more about Greenville

Stroll through the historic downtown square where vintage storefronts house local shops and the 'World's Largest Mailbox' stands proudly. Outdoor enthusiasts can hike scenic trails at nearby Patriot's Park or catch a baseball game at Greenville College's field during spring season.

See all hotels in Greenville
Autumns End is the end of another season as winter approaches

Top Greenville Hotel Reviews

Best Western Plus Centralia Hotel & Suites

Best Western Plus Centralia Hotel & Suites

10/10 Excellent
"Team was very welcoming and allowed us to check in a little early."
Czar 1-night trip
Posted 1 day ago
Best Western Plus Centralia Hotel & Suites

More cheap stays in Greenville

Super 8 by Wyndham Greenville

Super 8 by Wyndham Greenville

1700 State Route 127 Greenville IL
The price is ￥10,340 per night from Jan 13 to Jan 14
￥10,340
￥11,475 total
Jan 13 - Jan 14, 2026
includes taxes & fees
7.8/10 Good! (757 reviews)

Frequently asked questions

What's the best place to stay in Greenville?
Comfort Inn & Suites Greenville I-70 is a favorite property for Expedia customers. This hotel offers free breakfast and an indoor pool. Reviews from our site also recommend SureStay Hotel by Best Western Greenville and Super 8 by Wyndham Greenville as top options for your stay. See all available top hotels, or vacation rentals in Greenville.
What are some of the best vacation home rentals in Greenville?
The Aerie- Luxury Lakeside Getaway - Private Beach & Boatdock: Visitors like this Greenville vacation home rental. It is located on a lake and has a fireplace, a patio, and a barbecue grill to put you at ease in your new surroundings. It has 6 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You can relax into your vacation with a garden and a selection of games. Some other top choices in Greenville are THE NEST getaways&gatherings, beach/lake sleeps 20+ and The Beaumont Retreat. See all vacation rentals in Greenville.
If I need to cancel my hotel reservation in Greenville, will I receive a refund?
Yes, most hotel bookings are fully refundable if cancelled prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Greenville.
Where can I learn more about changing or cancelling my trip to Greenville?
For more details about picking new dates or cancelling your trip to Greenville, head over to our customer service page.
What's the best pet-friendly accommodation in Greenville?
SureStay Hotel by Best Western Greenville is a top hotel for people traveling with their pets, and offers an indoor pool and laundry facilities for its human guests. Super 8 by Wyndham Greenville is another option if you're bringing your pet along. See more pet-friendly hotel accommodations in Greenville.
What are some accommodations with pools in Greenville?
Comfort Inn & Suites Greenville I-70: Features buffet, an indoor pool, and free self parking. SureStay Hotel by Best Western Greenville and Baymont by Wyndham Litchfield are two additional hotels with an onsite pool. View all hotels with pools in Greenville.
What's the best place to stay near Lambert-St. Louis International Airport (STL)?
Marriott St. Louis Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.5 km) from Lambert-St. Louis Intl. Airport. Other good choices within close proximity to the airport include Pear Tree Inn Airport - St. Louis - St. Ann, MO and Drury Inn & Suites St. Louis Airport.
How is it staying in Greenville?
Visitors to Greenville are sure to enjoy the restaurants. Tourists can also enjoy so much more including its golf courses. In Greenville, there are 8 hotels and other accommodations to choose from. Find out more about Greenville.
What should I see while I'm in Greenville?
A couple of favorite places to visit are Greenville Country Club and Patriot's Park. You'll also find Copper Dock Winery and Carlyle Lake in the area. Check out what more to see and do in Expedia's Greenville guide.
What's the weather like in Greenville?
The hottest months are usually July and August with an average temp of 74°F, while the coldest months are January and February with an average of 36°F. Average annual precipitation for Greenville is 51 inches.

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