A brick wall with a street sign reading 'GREENVILLE ST.' and a black street lamp.

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Oct 30 - Nov 1
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Nov 6 - Nov 8

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Our top choices for Greenville hotels

A modern living room with a fireplace, blue sofa, red chairs, and a flat-screen TV mounted on a textured wall.

1. Comfort Inn & Suites Greenville I-70

Comfort Inn & Suites Greenville I-70
2.5 star property
Greenville
8.4 out of 10, Very good, (484 reviews)
"Very nice and quiet hotel. Breakfast was exceptional, we really enjoyed our stay."
United States
Debbie
The price is ￥16,308
￥18,099 total
includes taxes & fees
Nov 2 - Nov 3
Comfort Inn & Suites Greenville I-70
A hotel room with a bed, a television, a desk, and a chair.

2. Super 8 by Wyndham Greenville

Super 8 by Wyndham Greenville
2.0 star property
Greenville
8.0 out of 10, Very good, (859 reviews)
"Clean comfortable room right off the highway. Cute town with good restaurant. Fit our needs perfectly."
United States
Sharon
The price is ￥10,623
￥11,790 total
includes taxes & fees
Nov 26 - Nov 27
Super 8 by Wyndham Greenville
A hotel room with two beds, a desk, and a chair.

3. SureStay Hotel by Best Western Greenville

SureStay Hotel by Best Western Greenville
2.5 star property
Greenville
7.4 out of 10, Good, (623 reviews)
"good breakfest"
United States
jesse
The price is ￥8,632
￥9,580 total
includes taxes & fees
Nov 23 - Nov 24
SureStay Hotel by Best Western Greenville
A hotel room with a bed, bedside tables, a desk, a chair, a TV, and a window with curtains.

4. Budget Inn Motel

Budget Inn Motel
2.0 star property
Greenville
7.0 out of 10, Good, (199 reviews)
"Great for the price you pay"
United States
Steven
The price is ￥7,640
￥8,479 total
includes taxes & fees
Nov 10 - Nov 11
Budget Inn Motel
A buffet with various food items, including omelets and other dishes, arranged on a counter with a patterned tile backsplash.

5. Holiday Inn Express & Suites Vandalia by IHG

Holiday Inn Express & Suites Vandalia by IHG
2.5 star property
Vandalia
8.8 out of 10, Excellent, (868 reviews)
"Room was clean, parking was adequate. Breakfast was very good"
United States
Russell
The price is ￥17,537
￥19,111 total
includes taxes & fees
Nov 1 - Nov 2
Holiday Inn Express & Suites Vandalia by IHG
A hotel room with a large bathtub, a bedside table with a phone, and a neatly made bed.

6. Hampton Inn by Hilton Litchfield

Hampton Inn by Hilton Litchfield
2.5 star property
Litchfield
9.0 out of 10, Wonderful, (699 reviews)
"Good room and breakfast"
United States
Aimee
The price is ￥16,599
￥18,256 total
includes taxes & fees
Nov 8 - Nov 9
Hampton Inn by Hilton Litchfield
A modern living room with patterned carpet, two sofas, a coffee table, and a TV.

7. Super 8 by Wyndham Staunton

Super 8 by Wyndham Staunton
2.0 star property
Staunton
8.6 out of 10, Excellent, (824 reviews)
"It was a good location and served our needs for a night"
United States
Shelby
The price is ￥13,387
￥14,856 total
includes taxes & fees
Nov 26 - Nov 27
Super 8 by Wyndham Staunton
A neatly made bed with a patterned bedspread, a framed picture above it, a chair, a lamp, and a checkered floor.

8. Powhatan Motel

Powhatan Motel
2.5 star property
Pocahontas
8.6 out of 10, Excellent, (229 reviews)
"Basic, old style motel. Room was clean and food was excellent."
United States
Bob
The price is ￥15,237
￥16,149 total
includes taxes & fees
Nov 13 - Nov 14
Powhatan Motel
An indoor swimming pool with a clear view of the sky through the roof, surrounded by red lounge chairs and a few tables.

9. Baymont by Wyndham Litchfield

Baymont by Wyndham Litchfield
2.5 star property
Litchfield
8.2 out of 10, Very good, (1,002 reviews)
"Nice staff and nice place!"
United States
Kathy
The price is ￥14,962
￥16,455 total
includes taxes & fees
Oct 29 - Oct 30
Baymont by Wyndham Litchfield
A hotel room with a bed, a desk with a chair, a sofa, and a small table.

10. Quality Inn & Suites Vandalia near I-70 and Hwy 51

Quality Inn & Suites Vandalia near I-70 and Hwy 51
2.5 star property
Vandalia
8.2 out of 10, Very good, (1,003 reviews)
"Nothing unique, just a comfortable place to stay for a short time."
United States
Raymond
The price is ￥10,754
￥11,719 total
includes taxes & fees
Nov 4 - Nov 5
Quality Inn & Suites Vandalia near I-70 and Hwy 51
A multi-story hotel with a central entrance, illuminated by exterior lights, and a clear sky in the background.

11. Best Western Plus Centralia Hotel & Suites

Best Western Plus Centralia Hotel & Suites
2.5 star property
Centralia
9.6 out of 10, Exceptional, (684 reviews)
"We stayed here with 2 adults and 3 kids and it was perfect. We highly recommend staying here"
United States
Jeremy
The price is ￥21,891
￥24,513 total
includes taxes & fees
Oct 29 - Oct 30
Best Western Plus Centralia Hotel & Suites
A lobby with a wooden staircase, a desk with a computer, and patterned armchairs.

12. Ramada by Wyndham Vandalia

Ramada by Wyndham Vandalia
2.0 star property
Vandalia
7.8 out of 10, Good, (876 reviews)
"Staff is always helpful and welcoming."
United States
Samantha
The price is ￥12,599
￥13,730 total
includes taxes & fees
Nov 4 - Nov 5
Ramada by Wyndham Vandalia
A spacious living room with a fireplace, a television, and a modern chandelier.

13. Quality Inn Litchfield Route 66

Quality Inn Litchfield Route 66
2.5 star property
Litchfield
8.6 out of 10, Excellent, (718 reviews)
"Good location. Couch was broken down but otherwise a good stay."
United States
Franklin
The price is ￥12,851
￥14,133 total
includes taxes & fees
Nov 17 - Nov 18
Quality Inn Litchfield Route 66
A hotel room with a large bed, a red bedspread, a bathtub, a nightstand with a lamp, and two framed pictures on the wall.

14. Seasons Inn & Suites Highland

Seasons Inn & Suites Highland
2.5 star property
Highland
8.0 out of 10, Very good, (698 reviews)
"Front desk was very helpful and friendly. Reasonably priced and clean."
United States
Jeffrey
The price is ￥14,396
￥15,977 total
includes taxes & fees
Nov 25 - Nov 26
Seasons Inn & Suites Highland
A building with a covered entrance, stone pillars, and a bench outside.

15. Holiday Inn Express & Suites Litchfield West by IHG

Holiday Inn Express & Suites Litchfield West by IHG
2.5 star property
Litchfield
9.6 out of 10, Exceptional, (674 reviews)
"I enjoyed the proximity to Route 66 and the long sidewalk next to the prairie for long walks."
United States
Michael
The price is ￥19,371
￥21,304 total
includes taxes & fees
Nov 27 - Nov 28
Holiday Inn Express & Suites Litchfield West by IHG
A restaurant with a bar area, seating, and a view of the outside.

16. Americas Best Value Inn Vandalia

Americas Best Value Inn Vandalia
2.0 star property
Vandalia
7.8 out of 10, Good, (220 reviews)
"Quiet, clean, convenient comfortable bed and a good breakfast of waffles, cereal, yogurt, and juice. Old building, but rooms well refurbished"
Canada
Paula
The price is ￥10,114
￥11,023 total
includes taxes & fees
Oct 29 - Oct 30
Americas Best Value Inn Vandalia
An ice dispenser with a sign indicating it's for ice machines, a caution sign about not filling ice chests, and a plant in the foreground.

17. Motel 6 Litchfield, IL

Motel 6 Litchfield, IL
2.0 star property
Litchfield
7.2 out of 10, Good, (185 reviews)
"The man at the front desk was friendly, both at check in and check out."
United States
Pam
The price is ￥10,235
￥11,256 total
includes taxes & fees
Oct 29 - Oct 30
Motel 6 Litchfield, IL
A riverside view with a gravel path and a building with a red facade.

18. Innkeeper Motel

Innkeeper Motel
2.0 star property
Hamel
7.6 out of 10, Good, (11 reviews)
"Older property with no extras, Clean and updated rooms."
United States
Timothy
The price is ￥8,460
￥9,389 total
includes taxes & fees
Nov 17 - Nov 18
Innkeeper Motel
A hotel room with a bed, a chair, a small table, a lamp, a television, and a window with curtains.

19. Countryside Inn

Countryside Inn
2.0 star property
Hillsboro
5.6 out of 10, (41 reviews)
"The space is excellent and includes more than the usual room--full kitchen, for example. Staff are exceptionally welcoming and skilled. "
United States
Susanne
The price is ￥12,434
￥13,675 total
includes taxes & fees
Nov 8 - Nov 9
Countryside Inn
A white door with the number 16, a mailbox, and a small light fixture on the left.

20. Lighthouse Lodge

Lighthouse Lodge
2.0 star property
Pocahontas
8.6 out of 10, Excellent, (30 reviews)
"Check-in as at the gas station directly next door. We arrived very late, but the store clerk was friendly and helpful. Room was clean and comfortable."
United States
Danica
The price is ￥13,182
￥13,970 total
includes taxes & fees
Oct 30 - Oct 31
Lighthouse Lodge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Greenville attractions

Patriot's Park

8.4/10 (14 reviews)
This peaceful community park offers scenic trails around a serene lake, plus disc golf and playgrounds. Enjoy a morning walk through wooded areas to spot local wildlife or cast a line for some relaxing fishing.
See properties

Learn more about Greenville

Stroll through the historic downtown square where vintage storefronts house local shops and the 'World's Largest Mailbox' stands proudly. Outdoor enthusiasts can hike scenic trails at nearby Patriot's Park or catch a baseball game at Greenville College's field during spring season.

See all hotels in Greenville
A brick wall with a street sign reading 'GREENVILLE ST.' and a black street lamp.

Top Greenville Hotel Reviews

Comfort Inn & Suites Greenville I-70

Comfort Inn & Suites Greenville I-70

10/10 Excellent
"Staff was very friendly. Hot well maintained"
Ryan 3-night trip
Posted 17 hours ago
Comfort Inn & Suites Greenville I-70

More cheap stays in Greenville

Quality Inn Litchfield Route 66

Quality Inn Litchfield Route 66

1010 E Columbian Blvd N Litchfield IL
The price is ￥12,851 per night from Nov 17 to Nov 18
￥12,851
￥14,133 total
Nov 17 - Nov 18
includes taxes & fees
8.6/10 Excellent! (718 reviews)

Frequently asked questions

What's the best place to stay in Greenville?
Comfort Inn & Suites Greenville I-70 is one of the top choices for your stay based on our traveler data. This hotel offers free breakfast and an indoor pool. Other good choices for your trip include Super 8 by Wyndham Greenville and SureStay Hotel by Best Western Greenville. See all available top hotels, or vacation rentals in Greenville.
What are some of the best vacation home rentals in Greenville?
Private 7-Acre Multi Family Retreat Perfect for Reunions or Other Venues: Visitors like this Greenville vacation home rental. It offers an outdoor pool, a fireplace, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a balcony and a selection of games. Some other top choices in Greenville are THE NEST getaways&gatherings, beach/lake sleeps 20+ and The Beaumont Suite !. See all vacation rentals in Greenville.
If I need to cancel my hotel reservation in Greenville, will I receive a refund?
Yes, most hotel bookings are fully refundable if cancelled prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Greenville.
Where can I learn more about changing or cancelling my trip to Greenville?
For more details about picking new dates or cancelling your trip to Greenville, head over to our customer service page.
What's the best pet-friendly accommodation in Greenville?
SureStay Hotel by Best Western Greenville is a top hotel for people traveling with their pets, and offers an indoor pool and laundry facilities for its human guests. Super 8 by Wyndham Greenville is another option if you're bringing your pet along. See more pet-friendly hotel accommodations in Greenville.
What are some accommodations with pools in Greenville?
Comfort Inn & Suites Greenville I-70: Features buffet, an indoor pool, and free self parking. SureStay Hotel by Best Western Greenville and Private 7-Acre Multi Family Retreat Perfect for Reunions or Other Venues are two additional hotels with an onsite pool. View all hotels with pools in Greenville.
What's the best place to stay near Lambert-St. Louis International Airport (STL)?
Marriott St. Louis Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.5 km) from Lambert-St. Louis Intl. Airport. Other good choices within close proximity to the airport include Pear Tree Inn Airport - St. Louis - St. Ann, MO and Drury Inn & Suites St. Louis Airport.
How is it staying in Greenville?
Visitors to Greenville are sure to enjoy the restaurants. Tourists can also enjoy so much more including its golf courses. In Greenville, there are 9 hotels and other accommodations to choose from. Find out more about Greenville.
What should I see while I'm in Greenville?
A couple of favorite places to visit are Greenville Country Club and Patriot's Park. You'll also find Carlyle Lake and Silver Lake Park in the area. Check out what more to see and do in Expedia's Greenville guide.
What's the weather like in Greenville?
The hottest months are usually July and August with an average temp of 74°F, while the coldest months are January and February with an average of 36°F. Average annual precipitation for Greenville is 51 inches.

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