Top 10 Hotels in Effingham, SC from ￥11,425 - Competitive Prices

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in Effingham

Pet friendly

Apartment

Pool

Condo

Hot tub

Family friendly

Waterpark

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Our top choices for Effingham hotels

A hotel room with a large bed, a desk with a chair, a television, and a walk-in closet.

A reception area with a modern design, featuring a reception desk, a digital display, and a sign for Holiday Inn Express & Suites.

A coffee station with two coffee machines and a display of coffee pods and cups.

A hotel pool area with two pools, a lifeguard stand, and a towel service station.

1. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Florence

Leigh

￥18,001

￥20,161 total

includes taxes & fees

Oct 18 - Oct 19

A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.

A modern bar area with a long counter, multiple bar stools, and a variety of bottles and glasses.

A modern bar area with a long counter, bar stools, and a variety of bottles and glasses.

A modern lounge area with brick walls, large windows, and contemporary furniture.

2. Hyatt Place Florence Downtown

Florence

Ivette

￥15,831

￥17,732 total

includes taxes & fees

Nov 2 - Nov 3

A hotel lobby with a reception desk, seating area, and a television screen.

A hotel room with a bed, a sofa, an ottoman, and a lamp.

A spacious dining area with multiple tables and chairs, large windows, and a flat-screen TV mounted on the wall.

A hotel room with a sectional sofa, two ottomans, a bed with a green bedspread, and framed pictures on the wall.

3. Comfort Inn & Suites Florence Center Area

Florence

Mila

￥16,013

￥17,935 total

includes taxes & fees

Nov 1 - Nov 2

A hotel entrance with a stone facade, glass doors, and a number '501' above.

An indoor swimming pool with a tiled floor, a pool ladder, and lounge chairs.

A modern living room with a stone fireplace, a blue sofa, a brown leather chair, and a round coffee table.

A hotel reception area with a wooden floor, a reception desk, a seating area with chairs, and a decorative wall with a tree pattern.

4. Fairfield Inn & Suites by Marriott Florence I-20

Florence

Alma

￥18,704

￥20,950 total

includes taxes & fees

Oct 25 - Oct 26

An outdoor patio area with wicker furniture, a wooden pergola, and a barbecue setup.

A hotel with a sign reading "Homewood Suites Hilton" and a landscaped entrance area with a circular brick pathway and benches.

A modern kitchen with dark wood cabinets, a central island with a glass enclosure, and a white countertop.

A modern lobby with a round table, sofas, and a reception desk.

5. Homewood Suites by Hilton Florence

Florence

Aekyung

￥16,686

￥20,255 total

includes taxes & fees

Nov 1 - Nov 2

A spacious lobby with a reception desk, seating area, and large windows.

A Hilton Garden Inn with a large, multi-story building, a covered entrance, and a parking lot.

A spacious lobby with a large fireplace, comfortable seating, and potted plants.

An indoor swimming pool with clear poolside areas, a lifeguard station, and a view of the outside.

6. Hilton Garden Inn Florence

Florence

Derrick

￥18,656

￥20,895 total

includes taxes & fees

Oct 18 - Oct 19

A hotel room with two beds, a wooden headboard, a window with curtains, and a wall-mounted air conditioner.

A spacious lobby with a reception desk, a large window display, and a 'market' sign on the wall.

A modern kitchen with a built-in coffee station, a refrigerator, and a seating area with a patterned rug.

7. SpringHill Suites by Marriott Florence

Florence

John

￥14,629

￥17,324 total

includes taxes & fees

Oct 18 - Oct 19

A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.

A lobby with a fireplace, seating area, and a television.

A hotel lobby with a reception desk, seating area, and a welcome mat.

A hotel room with two beds, a desk, a TV, and a window with patterned curtains.

8. Hampton Inn & Suites Florence Center

Florence

Ryan

￥17,985

￥20,143 total

includes taxes & fees

Oct 18 - Oct 19

A hotel room with a bed, a desk, a green sofa, and a painting on the wall.

A spacious lobby with a reception desk, seating area with patterned chairs, and a coffee station.

A hotel room with a desk, a green armchair, a small purple ottoman, a bed with a white headboard, and a large window.

9. Home2 Suites by Hilton Florence, SC

Florence

saleh

￥17,353

￥20,375 total

includes taxes & fees

Oct 18 - Oct 19

A restaurant with brick walls, framed awards, and a bar area.

An outdoor patio area with a brick wall, a covered seating area with string lights, and potted plants.

A spacious living room with a wooden floor, a ceiling fan, and a dining area with a wooden table and chairs.

A bar area with a curved counter, multiple stools, and a brick wall backdrop.

10. Hotel Florence, Tapestry Collection by Hilton

Florence

Ankh

￥18,174

￥20,356 total

includes taxes & fees

Nov 1 - Nov 2

A modern kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker. There is a dining area with two red chairs and a table.

A conference room with round tables, chairs, and a carpeted floor.

A hotel room with a bed, a desk, a TV, a refrigerator, and a painting on the wall.

An outdoor kitchen area with a grill, a pool, and a covered seating area.

11. Staybridge Suites Florence - Civic Center by IHG

Florence

Tishia

￥21,372

￥23,935 total

includes taxes & fees

Nov 1 - Nov 2

A spacious lobby with a high ceiling, a central seating area with armchairs and a coffee table, a flat-screen TV, and a dining area with tables and chairs.

A modern hotel lobby with a fireplace, seating area, and a reception desk.

A hotel with a modern design, featuring multiple floors and a parking lot.

A modern hotel lobby with a central seating area, a large abstract painting, and a patterned carpet.

12. Residence Inn Marriott Florence

Florence

Teri

￥17,604

￥19,717 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.

A reception area with a wooden desk, a map on the wall, and a sign welcoming visitors to Florence, SC.

A self-service beverage station with refrigerated and non-refrigerated drink options, snack shelves, and a sign indicating the location.

A hotel with a central entrance, multiple floors, and a parking lot.

13. TownePlace Suites by Marriott Florence

Florence

Crystal

￥17,359

￥19,444 total

includes taxes & fees

Nov 2 - Nov 3

A spacious lobby with a checkered floor, a reception desk, and a chandelier.

A two-story building with a brick facade, a flat roof, and a covered entrance area.

A hotel room with two beds, a desk with a computer, a chair, and a bathroom with a mirror.

A vending area with snack and drink options, including Pepsi refrigerators and a 'MARKET' display with various products.

14. Howard Johnson by Wyndham Florence

Florence

HOMERO

￥10,200

￥11,425 total

includes taxes & fees

Oct 18 - Oct 19

A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.

A hotel room with a large bed, a desk with a lamp, a chair, a TV, and a window with curtains.

A modern kitchen with a patterned backsplash, wooden cabinets, and stainless steel appliances.

A modern living room with a grey sofa, a flat-screen TV, geometric wall art, and a bookshelf with decorative items.

15. Park Inn by Radisson Florence, SC

Florence

Windia

￥14,100

￥15,792 total

includes taxes & fees

Oct 18 - Oct 19

A modern hotel with a covered entrance, large windows, and a sign indicating it is a hotel.

A modern kitchen with a white countertop, three black stools, and a red accent wall.

A modern lounge area with a pool table, sofas, and yellow chairs.

16. Aloft by Marriott Florence

Florence

SARAH

￥17,558

￥20,605 total

includes taxes & fees

Oct 18 - Oct 19

An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.

A modern lounge area with seating, tables, and a pool table.

A modern hotel restaurant with a breakfast bar, seating area, and a view of the city.

A modern hotel with a prominent 'TRU by Hilton' sign, a well-lit entrance, and a landscaped front yard.

17. Tru by Hilton Florence I-95

Florence

Tiffany

￥15,972

￥18,829 total

includes taxes & fees

Oct 25 - Oct 26

A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.

A lobby with leather sofas, a coffee table, potted plants, and a reception desk.

A corridor with shelves stocked with snacks and a frozen food display.

A Hampton Inn & Suites hotel with a well-lit entrance, multiple floors, and a parking area.

18. Hampton Inn & Suites Florence-North-I-95

Florence

Ashokraju

￥19,327

￥21,647 total

includes taxes & fees

Oct 18 - Oct 19

A hotel room with a desk, chair, bed, and a yellow sofa.

A reception desk with a stone wall backdrop, a sign reading 'Quality Choice Hotels,' and a reception area with a wooden reception desk and two chairs.

A hotel dining area with wooden tables and chairs, a fireplace, and a television.

A swimming pool with lounge chairs and a building with balconies.

19. Quality Inn & Suites Florence Civic Center

Florence

Sharhonda

￥13,927

￥15,597 total

includes taxes & fees

Oct 18 - Oct 19

A hotel room with two beds, a desk with a TV, and a bathroom visible through an open door.

A breakfast buffet with a variety of food items, including pastries and cereal boxes, and a sign indicating the availability of cinnamon sweet rolls.

A large, two-story building with a central entrance flanked by columns, labeled "DIR FRANK B. LEE NURSING BUILDING."

An outdoor patio area with brick walls, a fire pit, and outdoor seating.

20. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

Florence

Christopher

￥19,264

￥23,138 total

includes taxes & fees

Oct 18 - Oct 19

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Top Effingham Hotel Reviews

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

8/10 Good

"Good"

Howard Johnson by Wyndham Florence

8/10 Good

"The air conditioner was not as cold as the last time we were there but overall good place"

La Quinta Inn & Suites by Wyndham Florence

10/10 Excellent

"Room was very clean and well presented. Bathroom was large and well stocked with extra tissue, towels, and shower had complementary shampoo, body wash and conditioner. Room had mini fridge and microwave. Large screen tv with all needed channels plus HBO. Breakfast buffet was excellent as well as all staff present. A very big bonus for us is the place is PET FRIENDLY!!! We will be back!"

Super 8 by Wyndham Florence

10/10 Excellent

"Room was clean. Bed was comfortable. This was a stop for the night, but we were happy with it, especially for the reasonable price."

Aloft by Marriott Florence

8/10 Good

"Room was clean. Staff was helpful."

Comfort Suites Florence I-95

10/10 Excellent

"Everything was excellent- the staff, the rooms, the parking, you name it. Very satisfied"

Spark by Hilton Florence North I-95, SC

10/10 Excellent

"Overview... it was Excellent. Clean, very comfortable spacious and convenient to restaurants. Staff was helpful and nice. Updates were very nice.Would definitely stay again."

Best Western Executive Inn

10/10 Excellent

"Not necessarily unique property. However, the staff were so kind!! We would stay here again for sure! Thank you ladies - from desk to housekeeping!!"

Comfort Inn & Suites Florence Center Area

8/10 Good

"Nothing to say"

More cheap stays in Effingham

Howard Johnson by Wyndham Florence

2038 W Lucas Street Florence SC

￥10,200

￥11,425 total

Oct 14 - Oct 15

includes taxes & fees

8.6/10 Excellent! (2,742 reviews)

Days Inn by Wyndham Florence Near Civic Center

140 Dunbarton Dr Florence SC

￥10,290

￥11,525 total

Oct 15 - Oct 16

includes taxes & fees

Quality Inn & Suites Florence Civic Center

150 Dunbarton Dr Florence SC

￥13,927

￥15,597 total

Oct 18 - Oct 19

includes taxes & fees

Park Inn by Radisson Florence, SC

1729 Mandeville Road Florence SC

￥14,100

￥15,792 total

Oct 18 - Oct 19

includes taxes & fees

Comfort Inn & Suites Florence Center Area

527 Woody Jones Blvd Florence SC

￥16,013

￥17,935 total

Nov 1 - Nov 2

includes taxes & fees

9/10 Wonderful! (1,367 reviews)

The Inn at the Crossroads

128 West Main Street Lake City SC

￥16,060

￥17,987 total

Nov 10 - Nov 11

includes taxes & fees

Frequently asked questions

Where is the best place to stay in Effingham?

Park Inn by Radisson Florence, SC, located 12.2 mi (19.6 km) from the heart of Effingham, is a top choice for your stay based on our traveler data. Other good options for your stay in the area are Howard Johnson by Wyndham Florence and Quality Inn & Suites Florence Civic Center. See all available top hotels, or vacation rentals in Effingham.

What's the top vacation rental that Effingham has to offer?

Stunning historic home w/ large rooms. Close to attractions. Kid & pet friendly!: This vacation home rental near Effingham is located on a lake and has a balcony, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 5 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games. See all vacation rentals in Effingham.

If I need to cancel my hotel reservation in Effingham, will I receive a refund?

Yes, the majority of hotel bookings are fully refundable if cancelled before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Effingham.

Where can I learn more about changing or cancelling my trip to Effingham?

For more details about changing or cancelling your trip to Effingham, click here.

How is it to stay in Effingham?

Travelers to Effingham will find plenty to explore and enjoy. There are 160 hotels and other accommodations in the surrounding area. Find out more about Effingham.

What should I see while I'm in Effingham?

A favorite place to visit is Lynches River State Park. You'll also find Florence National Cemetery and Florence County Museum in the area. Check out what more to see and do in Expedia's Effingham guide.

What's the weather like in Effingham?

The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and February with an average of 50°F. Average annual precipitation for Effingham is 54 inches.

Explore a world of travel with Expedia

Pinewood Vacation Rentals

Book Hotels in Effingham on Expedia.com

Find hotels in Effingham, SC from ￥11,425

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Effingham

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for Effingham hotels

1. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

2. Hyatt Place Florence Downtown

3. Comfort Inn & Suites Florence Center Area

4. Fairfield Inn & Suites by Marriott Florence I-20

5. Homewood Suites by Hilton Florence

6. Hilton Garden Inn Florence

7. SpringHill Suites by Marriott Florence

8. Hampton Inn & Suites Florence Center

9. Home2 Suites by Hilton Florence, SC

10. Hotel Florence, Tapestry Collection by Hilton

11. Staybridge Suites Florence - Civic Center by IHG

12. Residence Inn Marriott Florence

13. TownePlace Suites by Marriott Florence

14. Howard Johnson by Wyndham Florence

15. Park Inn by Radisson Florence, SC

16. Aloft by Marriott Florence

17. Tru by Hilton Florence I-95

18. Hampton Inn & Suites Florence-North-I-95

19. Quality Inn & Suites Florence Civic Center

20. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

Top Effingham Hotel Reviews

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

Howard Johnson by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

Super 8 by Wyndham Florence

Aloft by Marriott Florence

Comfort Suites Florence I-95

Spark by Hilton Florence North I-95, SC

Best Western Executive Inn

Comfort Inn & Suites Florence Center Area

More cheap stays in Effingham

Howard Johnson by Wyndham Florence

Days Inn by Wyndham Florence Near Civic Center

Quality Inn & Suites Florence Civic Center

Park Inn by Radisson Florence, SC

Comfort Inn & Suites Florence Center Area

The Inn at the Crossroads

Frequently asked questions

Explore a world of travel with Expedia

Go further with the Expedia app