Effingham Vacation Rentals

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Check prices for these dates

In two weeks
Apr 24 - Apr 26
In two months
Jun 5 - Jun 7
In three months
Jul 3 - Jul 5
In four months
Jul 31 - Aug 2

Our top choices for Effingham vacation rentals

1 bedroom, iron/ironing board, travel crib, free WiFi

Charming Cottage with easy access to local attractions-pet and kid friendly

Charming Cottage with easy access to local attractions-pet and kid friendly
Sellers
9.6 out of 10, Exceptional, (24 reviews)
"Great host!!"
United States
Donna H.
The price is ￥15,034
￥31,128 total
includes taxes & fees
Apr 19 - Apr 20
Charming Cottage with easy access to local attractions-pet and kid friendly
Interior

Secret SC Cabin on 100 acres Hot Tub Large Pond

Secret SC Cabin on 100 acres Hot Tub Large Pond
Marion
9.6 out of 10, Exceptional, (183 reviews)
"Great location and house and the host was excellent!"
United States
Josh R.
The price is ￥32,216
￥74,827 total
includes taxes & fees
Apr 14 - Apr 15
Secret SC Cabin on 100 acres Hot Tub Large Pond
Interior

Walking distance from one of South Carolina's top Medical centers.

Walking distance from one of South Carolina's top Medical centers.
Florence
9.8 out of 10, Exceptional, (49 reviews)
"Everything was great!"
United States
Debra B.
The price is ￥21,334
￥36,366 total
includes taxes & fees
Apr 13 - Apr 14
Walking distance from one of South Carolina's top Medical centers.
Dining

Located in Marion. Only 1 hour from Myrtle Beach, 35 minutes from Florence!

Located in Marion. Only 1 hour from Myrtle Beach, 35 minutes from Florence!
Marion
9.0 out of 10, Wonderful, (6 reviews)
"It was a great place. "
United States
Cindy N.
The price is ￥31,818
￥95,201 total
includes taxes & fees
Apr 12 - Apr 13
Located in Marion. Only 1 hour from Myrtle Beach, 35 minutes from Florence!
Dining

Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence.

Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence.
Florence
8.6 out of 10, Excellent, (4 reviews)
"Convenient location"
United States
Bonney W.
The price is ￥24,846
￥81,699 total
includes taxes & fees
Apr 13 - Apr 14
Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence.
Interior

Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's

Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's
Florence
10.0 out of 10, Exceptional, (50 reviews)
"The host was very welcoming. The house is so nice and clean and comfortable. One of the best I've ever stayed at. "
United States
Gail H.
The price is ￥40,520
￥51,262 total
includes taxes & fees
Apr 13 - Apr 14
Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's
Fridge, microwave, oven, stovetop

The Pinecone Retreat - Only 1 mile from i95

The Pinecone Retreat - Only 1 mile from i95
Latta
The price is ￥15,909
￥20,809 total
includes taxes & fees
Apr 12 - Apr 13
The Pinecone Retreat - Only 1 mile from i95
Interior

Perfect Stop • Near I-95, Downtown & Civic Center and Darlington

Perfect Stop • Near I-95, Downtown & Civic Center and Darlington
Florence
9.8 out of 10, Exceptional, (8 reviews)
"It was perfect! And the host was the best everrrr I loved every second I will be returning! "
United States
Kimesha C.
The price is ￥35,509
￥44,758 total
includes taxes & fees
Apr 12 - Apr 13
Perfect Stop • Near I-95, Downtown & Civic Center and Darlington
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Effingham Hotel Reviews

SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence

2/10 Terrible
"I booked with Expedia a month ahead of time and because the hotel overbooked, they cancelled my reservation and lied to me, saying Expedia cancelled it. The manager on duty 4/4/26 about 6pm also lied to me and then would not come back out to speak with me after I talked to Expedia. A nightmare for my grandkids Spring Break vacation"
Angel 1-night trip
Posted 6 hours ago
SpringHill Suites by Marriott Florence

Find out more about Effingham

Search for holiday rentals in Effingham on Expedia! You can easily find your home rentals, villas, holiday apartments in Effingham using one of the methods below:

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Look no further and take a look at our great range of rental properties in Effingham!

Frequently asked questions

Can I find vacation rentals in Effingham?

Yes, we have vacation rentals close to popular attractions in Effingham, or you can choose a more secluded option if you want a relaxing place to stay.

What are some of the best vacation rentals in Effingham?

Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's: Visitors like this Effingham vacation home rental. It offers a fireplace, a patio, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the garden in this rental home to help you unwind.

What’s there to see and do in Effingham?

While you're exploring the area, Palmetto Shores Lake and Florence Veterans Park are a couple of picturesque spots to get outside and enjoy nature. Lynches River State Park and Florence National Cemetery are a couple of places you'll find in the larger area.

What are vacation rentals like in Effingham?

Vacation rentals are privately owned properties you can reserve for a couple days or more in Effingham. Vacation rentals offer amenities like kitchens and laundry facilities so you'll have all the conveniences of home. If you're concerned about a sanitized environment, a vacation rental can offer a sense of security away from public hotel elevators and busy lobbies while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a great choice for a small group gathering.