Find hotels in Santee, SC from ￥10,116

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Mar 15 - Mar 16
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Mar 16 - Mar 17
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Mar 20 - Mar 22
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Mar 27 - Mar 29

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Our top choices for Santee hotels

Property amenity

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1,006 reviews)
"Clean comfortable stay. Breakfast was a nice plus."
United States
David
The price is ￥19,966
￥22,163 total
includes taxes & fees
Mar 22 - Mar 23
Fairfield Inn & Suites by Marriott Santee
Free breakfast

Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
2.5 star property
Santee
9.6 out of 10, Exceptional, (1,007 reviews)
"Clean, great staff"
United States
Joseph
The price is ￥21,319
￥23,665 total
includes taxes & fees
Mar 23 - Mar 24
Hampton Inn Santee-I-95
Exterior

Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,005 reviews)
"Clean room, polite staff , "
United States
samantha
The price is ￥17,890
￥19,858 total
includes taxes & fees
Mar 16 - Mar 17
Best Western Plus Santee Inn
Desk, blackout drapes, iron/ironing board, free WiFi

Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1,427 reviews)
"Room were very clean and staff was very helpful. I would stay there again."
United States
Charolette
The price is ￥12,777
￥14,183 total
includes taxes & fees
Mar 16 - Mar 17
Baymont by Wyndham Santee
In-room safe, iron/ironing board, free WiFi, bed sheets

Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
2.0 star property
Santee
7.2 out of 10, Good, (706 reviews)
"Good location for amenities and walking and driving distance "
United States
Gezeall
The price is ￥10,063
￥11,170 total
includes taxes & fees
Mar 16 - Mar 17
Travelodge by Wyndham Santee
Free daily buffet breakfast

Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (759 reviews)
"Great place to stay."
United States
Deborah
The price is ￥18,369
￥20,390 total
includes taxes & fees
Mar 23 - Mar 24
Tru By Hilton Santee
Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1,003 reviews)
"Hotel was a little dated but clean."
United States
Deborah
The price is ￥16,971
￥18,838 total
includes taxes & fees
Mar 22 - Mar 23
Comfort Inn & Suites Santee
Exterior

Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
3.0 star property
Santee
8.2 out of 10, Very Good, (1,001 reviews)
"Staff was amazing — but they were very short staffed so the one person at the bar/restaurant (Dee) and the one person at the desk did the job of 3 people each!! Place is being renovated so not quite there yet but clean and good stay. And again incredible staff!!! "
United States
Deborah
The price is ￥20,925
￥23,227 total
includes taxes & fees
Mar 22 - Mar 23
Holiday Inn Santee by IHG
Lobby

Super 8 by Wyndham Santee

Super 8 by Wyndham Santee
2.0 star property
Santee
6.8 out of 10, (446 reviews)
"The beds are super comfy. I liked how quiet it was in the room and the staff was very friendly "
United States
Kathy
The price is ￥11,980
￥13,298 total
includes taxes & fees
Mar 16 - Mar 17
Super 8 by Wyndham Santee
Free daily full breakfast

Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
2.5 star property
Santee
6.0 out of 10, (483 reviews)
"Rooms are updated and clean. Very good value for the price of the room. "
United States
Mark
The price is ￥8,689
￥10,530 total
includes taxes & fees
Mar 22 - Mar 23
Quality Inn & Suites Santee I-95
Exterior

Red Roof Inn Santee

Red Roof Inn Santee
2.0 star property
Santee
6.6 out of 10, (646 reviews)
"A good option if traveling with pets. The hotel is clean and well maintained but dated. "
United States
Karen
The price is ￥9,343
￥10,370 total
includes taxes & fees
Mar 22 - Mar 23
Red Roof Inn Santee
Desk, iron/ironing board, free WiFi, bed sheets

Econo Lodge Santee

Econo Lodge Santee
2.0 star property
Santee
6.4 out of 10, (311 reviews)
"Last minute arrangements stay was quiet and peaceful "
United States
Iasia
The price is ￥10,903
￥12,102 total
includes taxes & fees
Mar 29 - Mar 30
Econo Lodge Santee
Desk, blackout drapes, iron/ironing board, free WiFi

Peach Tree Inn

Peach Tree Inn
2.5 star property
St. George
7.4 out of 10, Good, (175 reviews)
"Clean carpetted floor.."
Canada
Conrad
The price is ￥10,782
￥11,645 total
includes taxes & fees
Mar 16 - Mar 17
Peach Tree Inn
Breakfast area

Travelodge by Wyndham Orangeburg

Travelodge by Wyndham Orangeburg
2.0 star property
Orangeburg
8.2 out of 10, Very Good, (1,005 reviews)
"Conveniently located just off I26, this motel is very clean and beds are comfortable and rooms are quiet. Rooms could use some updating but can’t complain for the price. Lots of restaurants around to choose from and motel supplies coffee and cereal for breakfast in front dining area. "
Canada
Yvonne
The price is ￥11,357
￥12,607 total
includes taxes & fees
Apr 14 - Apr 15
Travelodge by Wyndham Orangeburg
Free daily buffet breakfast

Tru by Hilton Orangeburg

Tru by Hilton Orangeburg
2.5 star property
Orangeburg
9.2 out of 10, Wonderful, (1,002 reviews)
"Excellent stopover for us!"
United States
Georgina
The price is ￥18,206
￥20,208 total
includes taxes & fees
Apr 5 - Apr 6
Tru by Hilton Orangeburg
Lobby

Fairfield Inn by Marriott Orangeburg

Fairfield Inn by Marriott Orangeburg
3.0 star property
Orangeburg
8.4 out of 10, Very Good, (737 reviews)
"Bed was wonderhul...very satisfied "
United States
catherine
The price is ￥14,120
￥15,674 total
includes taxes & fees
Apr 13 - Apr 14
Fairfield Inn by Marriott Orangeburg
Exterior

Hampton Inn & Suites Orangeburg

Hampton Inn & Suites Orangeburg
2.5 star property
Orangeburg
9.4 out of 10, Exceptional, (793 reviews)
"We travel regularly and this was the best breakfast of any of the places we had stayed. Facility was clean and service was friendly."
United States
Janet
The price is ￥21,303
￥23,647 total
includes taxes & fees
Mar 30 - Mar 31
Hampton Inn & Suites Orangeburg
Property amenity

SpringHill Suites by Marriott Orangeburg

SpringHill Suites by Marriott Orangeburg
2.5 star property
Orangeburg
8.8 out of 10, Excellent, (715 reviews)
"3rd stay at this location would highly recommend "
United States
Athanassios
The price is ￥20,945
￥23,249 total
includes taxes & fees
Apr 1 - Apr 2
SpringHill Suites by Marriott Orangeburg
Seasonal outdoor pool

Spark by Hilton Orangeburg

Spark by Hilton Orangeburg
2.5 star property
Orangeburg
7.8 out of 10, Good, (1,006 reviews)
"Newly Renovated, clean carpet, comfortable bed and pillows."
United States
Vivian
The price is ￥16,484
￥18,296 total
includes taxes & fees
Mar 22 - Mar 23
Spark by Hilton Orangeburg
Room, 2 Queen Beds, Accessible, Non Smoking (Efficiency) | Desk, iron/ironing board, free cribs/infant beds, free WiFi

Comfort Inn & Suites Orangeburg

Comfort Inn & Suites Orangeburg
2.5 star property
Orangeburg
8.0 out of 10, Very Good, (586 reviews)
"Great location "
United States
Cynthia
The price is ￥17,113
￥18,996 total
includes taxes & fees
Mar 24 - Mar 25
Comfort Inn & Suites Orangeburg
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Santee attractions

Santee State Park

4.0/5 (112 reviews)
Perched on Lake Marion's shores, Santee State Park offers unique rondette cabins built over water. Hike through cypress swamps and sinkholes while spotting alligators, fox squirrels, and diverse birdlife.
See properties

Santee Cooper Country Club

3.9/5 (47 reviews)
This George Cobb-designed course winds through majestic pines with strategic doglegs and panoramic Lake Marion views. Enjoy the signature closing hole and well-maintained fairways perfect for golfers of all skill levels.
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Learn more about Santee

Nestled along Lake Marion, this charming town offers prime fishing and boating opportunities for outdoor enthusiasts. Visitors can tee off at Santee National Golf Club or explore nearby Santee State Park's hiking trails and campgrounds.

See all hotels in Santee
Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina

Top Santee Hotel Reviews

Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95

8/10 Good
"The. Property is old, the facilities are old indeed, but they work alright. I recommend. To upgrade bathroom."
Maria 1-night trip
Posted 1 hour ago
Quality Inn & Suites Santee I-95

More cheap stays in Santee

Super 8 by Wyndham, Orangeburg

Super 8 by Wyndham, Orangeburg

3608 Saint Matthews Rd Orangeburg SC
The price is ￥9,200 per night from Mar 22 to Mar 23
￥9,200
￥10,212 total
Mar 22 - Mar 23
includes taxes & fees
6.8/10 (927 reviews)

Frequently asked questions

Where is the best place for a stay in Santee?
Hampton Inn Santee-I-95 is a favorite property for Expedia customers. This hotel offers free breakfast and free parking. Other top choices based on traveler reviews include Fairfield Inn & Suites by Marriott Santee and Tru By Hilton Santee. See all available top hotels, or vacation rentals in Santee.
What are some of the best vacation rentals in Santee?
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!: Visitors give good reviews to this Santee vacation home rental, which is located on a lake and has a patio, a selection of games, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. See all vacation rentals in Santee.
If I need to cancel my hotel reservation in Santee, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santee.
Where can I learn more about changing or cancelling my trip to Santee?
For more information about updating your trip to Santee or cancelling it, click here.
What's the best budget-friendly hotel in Santee?
Based on reviews, Baymont by Wyndham Santee is a popular hotel for our travelers who want a more economical choice, and features free breakfast and free WiFi. View all budget hotels in Santee.
What's the best hotel for a family vacation in Santee?
Fairfield Inn & Suites by Marriott Santee is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Comfort Inn & Suites Santee is another choice for your family trip. Find more child-friendly accommodations in Santee.
What is the top LGBTQ-friendly accommodation in Santee?
Fairfield Inn & Suites by Marriott Santee is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Hampton Inn Santee-I-95 and Holiday Inn Santee by IHG are other good options for your stay. See all available hotels listed as LGBTQ-friendly in Santee.
What's the best pet-friendly accommodation in Santee?
Baymont by Wyndham Santee is a top hotel for people traveling with their pets, and offers concierge services and free WiFi for its human guests. Other good choices for you and your pet's trip include Tru By Hilton Santee and Best Western Plus Santee Inn. See more pet-friendly hotel accommodations in Santee.
Where is the best place to stay near Santee State Park?
Baymont by Wyndham Santee is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free parking. It's located 3 mi (4.8 km) from Santee State Park. Other good choices within 5 miles include Best Western Plus Santee Inn and Holiday Inn Santee, an IHG Hotel.
What about the best place to stay close to Santee Outlets?
One of the top choices for your stay is Baymont by Wyndham Santee, located a short 0.4 mi (0.6 km) from Santee Outlets, and this hotel offers free breakfast and free parking. Best Western Plus Santee Inn and Fairfield Inn & Suites by Marriott Santee are two other good choices in the immediate area.
What's the best golf hotel in Santee?
Holiday Inn Santee by IHG is a top hotel that has an adjacent golf course and features free WiFi. Other good options to stay near a golf course include Ramada by Wyndham Santee I-95 and Super 8 by Wyndham Santee. Visit Santee Cooper Country Club or Santee National Golf Club to perfect your golf swing. See more golf hotels in Santee.
What are some accommodations with pools in Santee?
Fairfield Inn & Suites by Marriott Santee is a top hotel with a pool, free buffet breakfast, and free WiFi. Quality Inn & Suites Santee I-95 is another choice with an onsite pool. View all hotels with pools in Santee.
What's the best place to stay near Columbia Metropolitan Airport (CAE)?
Country Inn & Suites by Radisson, Columbia Airport, SC is a popular hotel, featuring free breakfast and an indoor pool. It's located a short 1.7 mi (2.8 km) from Columbia Metropolitan Airport. Other places to stay close to the airport are Sleep Inn Airport and Red Roof Inn Columbia, SC Airport.
What is staying in Santee like?
Families will find kid-friendly activities in Santee, and visitors give high marks for the top-notch restaurants. This welcoming city also attracts tourists with its golf courses and coffeehouses. In Santee, there are 125 hotels and other accommodations to choose from. Find out more about Santee.
What is there to see in Santee?
Favorite places to visit include Santee Cooper Country Club, Santee National Golf Club, and Santee State Park. A couple of additional sights to add to your agenda are Lake Marion and Santee Town Hall. Check out what more to see and do in Expedia's Santee guide.
What's the seasonal weather like in Santee?
The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 52°F. Average annual precipitation for Santee is 55 inches.

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