Santee Vacation Rentals

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Check prices for these dates

In two weeks
Oct 10 - Oct 12
In one month
Oct 24 - Oct 26
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Nov 21 - Nov 23
In three months
Dec 19 - Dec 21

Vacation Rentals in Santee

Our top choices for Santee vacation rentals

Wyndham Vacation Resorts Lake Marion
Exterior

Wyndham Vacation Resorts Lake Marion

4.0 star property
9.2 out of 10, Wonderful, (20)
"Friendly staff. Excellent accomodations. Peaceful and beautiful vacation."
Wyndham Vacation Resorts Lake Marion
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Smart TV, offices

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

10.0 out of 10, Exceptional, (35)
"1at class accommodations"
The price is ￥15,960
￥50,321 total
includes taxes & fees
Sep 30 - Oct 1
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Sunsets on Lake Marion
Property grounds

Sunsets on Lake Marion

9.4 out of 10, Exceptional, (13)
"Great place to stay. "
Sunsets on Lake Marion
Lake Marion - Majestic Big Water View!
Outdoor pool

Lake Marion - Majestic Big Water View!

10.0 out of 10, Exceptional, (9)
"Very very nice. Would recommend it for a great stay. "
Lake Marion - Majestic Big Water View!
Charming 2 Bedroom Waterfront Lake Marion Condo
Outdoor pool

Charming 2 Bedroom Waterfront Lake Marion Condo

10.0 out of 10, Exceptional, (4)
"Fantastic location on the lake and access to the pool as well. Home was clean and had everything we needed for our stay. Amazing communication with the owner. Will stay again."
Charming 2 Bedroom Waterfront Lake Marion Condo
Lakeside Charming 2-bedroom house in lovely Santee with AC, WiFi
Private kitchen

Lakeside Charming 2-bedroom house in lovely Santee with AC, WiFi

Lakeside Charming 2-bedroom house in lovely Santee with AC, WiFi
Lake Side Condo Getaway
Pool

Lake Side Condo Getaway

8.4 out of 10, Very Good, (8)
"My husband played in a golf tournament and I explored the area. Santee is home to a fabulous State Park, there are shopping and antiquing options, plenty of decent restaurants, Charleston is an easy drive and EVERYONE of the locals is helpful and hospitable. Tons of GREAT golf courses. Fishing is everywhere but we don’t fish."
Lake Side Condo Getaway
Lakeside vacationing close to golf courses, restaurants and boat rental company!
Pool

Lakeside vacationing close to golf courses, restaurants and boat rental company!

9.6 out of 10, Exceptional, (9)
"I had a very nice time and I will definitely come back here"
Lakeside vacationing close to golf courses, restaurants and boat rental company!
Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!
Smart TV, video games, books

Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!

10.0 out of 10, Exceptional, (9)
"Nice place great location "
Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!
Elloree Vacation Rental ~ 7 Mi to Lake Marion!
House (3 Bedrooms) | Interior

Elloree Vacation Rental ~ 7 Mi to Lake Marion!

3.0 star property
Elloree Vacation Rental ~ 7 Mi to Lake Marion!
Bells Marina & Resort
BBQ/picnic area

Bells Marina & Resort

2.5 star property
8.6 out of 10, Excellent, (75)
"Had a great stay"
Bells Marina & Resort
Pet friendly country cottage with large fenced-in yard & horses on property
Property grounds

Pet friendly country cottage with large fenced-in yard & horses on property

10.0 out of 10, Exceptional, (111)
"My daughter, dog and I were traveling from NC to Tampa, FL. on local roads and Kay's cottage was the best place to stop at! Her cottage has everything you need for a comfortable stay and a perfect fenced in front yard for our dog. We truly enjoyed our stay. Wish we could have stayed longer! "
The price is ￥16,606
￥30,232 total
includes taxes & fees
Sep 29 - Sep 30
Pet friendly country cottage with large fenced-in yard & horses on property
Lake Marion Lakehouse with 180° lake view
Exterior

Lake Marion Lakehouse with 180° lake view

10.0 out of 10, Exceptional, (71)
"I would stay here again. Great location."
Lake Marion Lakehouse with 180° lake view
SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable
Marina

SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable

9.6 out of 10, Exceptional, (241)
"The property was nice and had enough room for all 12 of us, 3 boats and all of the fishing equipment. Loved the long dock and the location that’s not far from the big water. We would stay here again when we come back to fish Lake Marion."
SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable
Sweet Marion - Dock + Boat Ramp + Hot Tub!
Terrace/patio

Sweet Marion - Dock + Boat Ramp + Hot Tub!

8.6 out of 10, Excellent, (15)
"Group of us older guys went for a golf weekend at Santee. The house was great and we really enjoyed our stay."
The price is ￥18,109
￥68,767 total
includes taxes & fees
Oct 20 - Oct 21
Sweet Marion - Dock + Boat Ramp + Hot Tub!
Country Resting Spot just off I95. 12 miles west on hwy 6.
Beach

Country Resting Spot just off I95. 12 miles west on hwy 6.

2.0 star property
9.2 out of 10, Wonderful, (19)
"It was very clean and had everything i needed. The host checked in with me while i was there though messages which was nice too. "
The price is ￥15,278
￥22,284 total
includes taxes & fees
Sep 25 - Sep 26
Country Resting Spot just off I95. 12 miles west on hwy 6.
Beautiful Lake Marion Views!! Pet Friendly! Newly renovated and updated!!
Fridge, microwave, oven, stovetop

Beautiful Lake Marion Views!! Pet Friendly! Newly renovated and updated!!

9.4 out of 10, Exceptional, (43)
"Clean house. Had a nice dock and view of lake. Owner live next door and was very friendly. Great place, would stay again."
Beautiful Lake Marion Views!! Pet Friendly! Newly renovated and updated!!
Waterfront with dock, less than 5 min to boat landing, gas, ABC and restaurant.
Property grounds

Waterfront with dock, less than 5 min to boat landing, gas, ABC and restaurant.

10.0 out of 10, Exceptional, (7)
"Nice dock, very shady waterfront all day long, and the screened in porch is so cozy. House has everything you need and then some. Cleanest rental I have seen and will be going back!"
Waterfront with dock, less than 5 min to boat landing, gas, ABC and restaurant.
Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy
Interior

Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy

9.8 out of 10, Exceptional, (90)
"Perfect for a big family. Loved the house and the location. Beautiful lake. A very happy stay. "
Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy
Big Mama's Lakeside Cottage Lake Marion
Fireplace

Big Mama's Lakeside Cottage Lake Marion

10.0 out of 10, Exceptional, (13)
"This is a very nice location, with great access to the lake."
Big Mama's Lakeside Cottage Lake Marion
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santee Hotel Reviews

Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

10/10 Excellent
"I like everything about this property! "
jillian 1-night trip
Posted 6 days ago
Hampton Inn Santee-I-95

Find out more about Santee

Find out more about Santee

Search for holiday rentals in Santee on Expedia! You can easily find your home rentals, villas, holiday apartments in Santee using one of the methods below:

  • View our selection of featured holiday rentals in Santee
  • Use the map to find apartments and other holiday homes in the Santee neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Santee while they last

Look no further and take a look at our great range of rental properties in Santee!

Frequently asked questions

Can I find vacation rentals in Santee?

Yes, we offer vacation rentals near the most popular points of interest in Santee, or you can select a more remote option if you'd like a relaxing place to stay. Tourists appreciate the top-notch restaurants and coffeehouses in Santee. Make sure you have time to check out the golf courses and lake views during your trip.

What are some of the best vacation home rentals in Santee?

Wyndham Vacation Resorts Lake Marion: This highly rated vacation home rental in Santee is equipped with an outdoor pool, a TV, and free WiFi to help you feel comfortable during your stay. It has 3 bedrooms as well as a kitchen with a full-sized fridge, a dishwasher, and a stovetop, so you can cook with friends or family. Another good choice for your trip to Santee is Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!.

How many vacation rentals are there in Santee?

Expedia has 9 vacation rentals for your stay in Santee.

What can I see and do in Santee?

While you're exploring the area, Lake Marion and Taw Caw Creek are a couple of picturesque spots to get outside and enjoy nature. Santee Cooper Country Club and Santee National Golf Club are other places to visit while you're in town.

What are vacation rentals like in Santee?

Vacation rentals are private accommodations you can book for several days or more in Santee. Vacation rentals feature amenities like kitchens and laundry facilities so you'll feel just like you're at home. If you're concerned about a sanitized environment, a vacation rental can provide a sense of safety away from public hotel elevators and bustling concierge desks while still allowing you the experience of travel. You'll also get more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a great choice for family gatherings.