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Compare 96 hotels in Mississippi County with room rates, reviews, and availability. Most hotels are fully refundable.

Our top choices for Mississippi County hotels

Super 8 by Wyndham Charleston/Sikeston East MO
Front of property - evening/night

Super 8 by Wyndham Charleston/Sikeston East MO

2.0 star property
6.6 out of 10, (585)
"Rooms was clean "
The price is ￥8,396
￥9,319 total
includes taxes & fees
Oct 2 - Oct 3
Super 8 by Wyndham Charleston/Sikeston East MO
Quality Inn Charleston - Sikeston
Desk, laptop workspace, blackout drapes, iron/ironing board

Quality Inn Charleston - Sikeston

2.5 star property
6.8 out of 10, (399)
"I consistently choose to stay there due to positive past encounters."
The price is ￥9,720
￥10,787 total
includes taxes & fees
Oct 6 - Oct 7
Quality Inn Charleston - Sikeston
Eagle Inn Charleston
Desk, iron/ironing board, free WiFi, alarm clocks

Eagle Inn Charleston

2.0 star property
6.8 out of 10, (100)
"Comfortable bed, easy access to room"
The price is ￥9,405
￥10,438 total
includes taxes & fees
Sep 7 - Sep 8
Eagle Inn Charleston
Quality Inn Cairo I-57
Lobby

Quality Inn Cairo I-57

2.5 star property
6.6 out of 10, (265)
"The hotel is in need of some serious upkeep and cleaning. It is in fairly poor condition, but it the only hotel in town."
The price is ￥10,025
￥11,125 total
includes taxes & fees
Oct 6 - Oct 7
Quality Inn Cairo I-57
Charming 3-bedroom house near ball park in quiet neighborhood
Fridge, microwave, oven, stovetop

Charming 3-bedroom house near ball park in quiet neighborhood

10.0 out of 10, Exceptional, (9)
"Quaint stay to see Grand and kids. "
The price is ￥13,269
￥23,676 total
includes taxes & fees
Sep 11 - Sep 12
Charming 3-bedroom house near ball park in quiet neighborhood
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mississippi County Hotel Reviews

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