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Our top choices for Charleston hotels

Room
Breakfast area
Lobby
Lobby

1. Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
Charleston
United States
Crystal
￥9,140
￥10,143 total
includes taxes & fees
Sep 13 - Sep 14
Super 8 by Wyndham Charleston/Sikeston East MO
Exterior
Breakfast buffet
Reception
Lobby sitting area

2. The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
Charleston
United States
Jay
￥10,213
￥11,334 total
includes taxes & fees
Sep 15 - Sep 16
The Riverstone Hotel Charleston-Sikeston
Room, 1 King Bed, Non Smoking | View from room
Room, 1 King Bed, Non Smoking | Bathroom
Room
Coffee service

3. Eagle Inn Charleston

Eagle Inn Charleston
Charleston
United States
Jackson
￥11,826
￥13,124 total
includes taxes & fees
Sep 13 - Sep 14
Eagle Inn Charleston
Pool
Lobby
Room
Property amenity

4. Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
Sikeston
United States
Scott Andrew
￥15,667
￥18,014 total
includes taxes & fees
Sep 17 - Sep 18
Drury Inn & Suites Sikeston, MO
Exterior
Lobby
Breakfast area
Pool

5. Hampton Inn Sikeston

Hampton Inn Sikeston
Sikeston
United States
Jeffrey
￥15,619
￥17,684 total
includes taxes & fees
Oct 11 - Oct 12
Hampton Inn Sikeston
Room, 1 King Bed, Accessible, Non Smoking
Breakfast area
Room
Suite, 2 Queen Beds, Non Smoking

6. Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
Sikeston
United States
Kevin
￥8,774
￥10,001 total
includes taxes & fees
Sep 20 - Sep 21
Super 8 by Wyndham Sikeston/Miner Area
Room
Exterior
Coffee service
Pool

7. Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
Sikeston
United States
michael
￥15,054
￥17,046 total
includes taxes & fees
Oct 11 - Oct 12
Holiday Inn Express & Suites Sikeston Southwest by IHG
Room
Breakfast area
Living area
Interior

8. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Sikeston
United States
Sharika West
￥9,607
￥10,949 total
includes taxes & fees
Sep 16 - Sep 17
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Breakfast area
Pool
Lobby
Standard Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (with Sofabed)

9. Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
Sikeston
United States
Bernice
￥13,393
￥15,265 total
includes taxes & fees
Sep 13 - Sep 14
Best Western Plus Sikeston I-55
Lobby
Standard Room, 1 King Bed, Non Smoking
Exterior
Lobby

10. Quality Inn Cairo I-57

Quality Inn Cairo I-57
Cairo
United States
Santiago
￥10,736
￥11,915 total
includes taxes & fees
Oct 2 - Oct 3
Quality Inn Cairo I-57
Room
Exterior
Lobby
Lobby

11. Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
Sikeston
United States
Val
￥10,186
￥11,610 total
includes taxes & fees
Sep 15 - Sep 16
Days Inn and Suites by Wyndham Sikeston
Property amenity
View from property
Bar (on property)
Pool

12. Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
Sikeston
United States
Allen
￥15,515
￥17,567 total
includes taxes & fees
Sep 20 - Sep 21
Fairfield Inn & Suites by Marriott Sikeston
Lobby
Pool
Lobby
Exterior

13. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
United States
Sandra
￥15,359
￥17,327 total
includes taxes & fees
Sep 17 - Sep 18
Drury Plaza Hotel Cape Girardeau Conference Center
Basic Double Room | Living area
Basic Double Room
Basic Double Room | Living area
Front of property

14. La Center Motel

La Center Motel
La Center
United States
Carrie
￥7,466
￥8,816 total
includes taxes & fees
Sep 20 - Sep 21
La Center Motel
Room
Lobby
Exterior
Breakfast area

15. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
Canada
Raidas
￥11,058
￥12,476 total
includes taxes & fees
Sep 20 - Sep 21
Pear Tree Inn Cape Girardeau West
Room
Food and drink
Food and drink
Food and drink

16. Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
Cape Girardeau
United States
Cheryl
￥13,823
￥15,594 total
includes taxes & fees
Sep 20 - Sep 21
Drury Inn & Suites Cape Girardeau
Exterior
Exterior
Indoor pool
Breakfast area

17. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
United States
ELAINE
￥15,515
￥17,657 total
includes taxes & fees
Sep 20 - Sep 21
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Exterior
Room
Pool
Lobby

18. Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
Sikeston
United States
Lakeysha
￥13,647
￥15,554 total
includes taxes & fees
Oct 4 - Oct 5
Comfort Inn & Suites Sikeston I-55
Lobby sitting area
Jackpot Suite | Living area
Bar (on property)
Restaurant

19. The Riverview

The Riverview
Cape Girardeau
United States
Alyssa
￥16,152
￥18,223 total
includes taxes & fees
Sep 16 - Sep 17
The Riverview
Room
Reception
Room
Exterior

20. Country Yard Inn and Suite

Country Yard Inn and Suite
Sikeston
United States
William
￥8,847
￥10,524 total
includes taxes & fees
Sep 16 - Sep 17
Country Yard Inn and Suite
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Learn more about Charleston

Quaint Charleston is calling! Discover its opera, entertainment, cathedral, and more.

See all hotels in Charleston
A sunset over a calm lake with tall trees reflected in the water.

Top Charleston Hotel Reviews

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

10/10 Excellent
"Excellent full breakfast."
Teresa 1-night trip
Posted 1 hour ago
Drury Inn & Suites Cape Girardeau
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

10/10 Excellent
"The nicest staff! Even the housekeeping staff, who were just walking in to start their shift and hadn’t even clocked in gave me a genuine “Good morning” and a smile. I love these people!"
Richard 2-night trip
Posted 5 hours ago
Pear Tree Inn Cape Girardeau West
The Riverview

The Riverview

10/10 Excellent
"I can’t rave enough about this hotel. 5 ♥️s. It takes zero effort to be kind. The staff is kind and helpful. Highly recommend to anyone staying in Cape Girardeau, MO. This hotel rises above the chain hotels 🏨."
Jennifer 1-night trip
Posted 8 hours ago
The Riverview
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

10/10 Excellent
"Excellent breakfast,friendly staff and clean rooms"
Serapia 1-night trip
Posted 11 hours ago
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston

10/10 Excellent
"A"
Barbara 1-night trip
Posted 2 days ago
Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

10/10 Excellent
"The receptionist was very courteous. Helped answer all my questions. We loved the room. And we had a great breakfast before we left."
David 1-night trip
Posted 4 days ago
Fairfield Inn & Suites by Marriott Cape Girardeau
Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

10/10 Excellent
"We had no problem checking in. The room was nice and clean. The staff were courteous and helpful. Parking was acceptable. Close to our room. No complaints."
Carol 2-night trip
Posted 4 days ago
Super 8 by Wyndham Sikeston/Miner Area
Hampton Inn Sikeston

Hampton Inn Sikeston

10/10 Excellent
"Really quiet place close to good restaurants and stores."
james 1-night trip
Posted 4 days ago
Hampton Inn Sikeston
The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston

10/10 Excellent
"Everything was fine for a one night stay."
Jay 1-night trip
Posted 6 days ago
The Riverstone Hotel Charleston-Sikeston

More cheap stays in Charleston

Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

2609 E Malone Ave Sikeston MO
￥8,774
￥10,001 total
Sep 20 - Sep 21
includes taxes & fees
7/10 Good! (673 reviews)
Super 8 by Wyndham Sikeston/Miner Area
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

100 Matthews Lane Sikeston MO
￥9,607
￥10,949 total
Sep 16 - Sep 17
includes taxes & fees
8.4/10 Very Good! (821 reviews)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO
￥10,186
￥11,610 total
Sep 15 - Sep 16
includes taxes & fees
Days Inn and Suites by Wyndham Sikeston
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy Cape Girardeau MO
￥11,058
￥12,476 total
Sep 20 - Sep 21
includes taxes & fees
9.2/10 Wonderful! (1,004 reviews)
Pear Tree Inn Cape Girardeau West
Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55

120 S Interstate Drive Sikeston MO
￥13,393
￥15,265 total
Sep 13 - Sep 14
includes taxes & fees
8.4/10 Very Good! (1,001 reviews)
Best Western Plus Sikeston I-55
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

3253 William Street Cape Girardeau MO
￥15,515
￥17,657 total
Sep 20 - Sep 21
includes taxes & fees
9.4/10 Exceptional! (1,002 reviews)
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Frequently asked questions

Where is the best place for a stay in Charleston?
Based on our traveler data, The Riverstone Hotel Charleston-Sikeston is one of the top choices for your stay. This hotel offers free breakfast and free parking. Other good options for your trip include Super 8 by Wyndham Charleston/Sikeston East MO and Eagle Inn Charleston. See all available top hotels, or vacation rentals in Charleston.
What's the top vacation rental that Charleston has to offer?
Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286: Visitors like this Charleston vacation home rental. It is located in a rural location and has a patio, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games. See all vacation rentals in Charleston.
If I need to cancel my hotel reservation in Charleston, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable if cancelled before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, you might still have the option to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Charleston.
Where can I learn more about changing or cancelling my trip to Charleston?
To find more details about changing or cancelling your trip to Charleston, click here.
What's the best LGBTQ-friendly place to stay in Charleston?
The Riverstone Hotel Charleston-Sikeston is a top LGBTQ-friendly hotel that features free breakfast and free WiFi.
What's the best pet-friendly hotel in Charleston?
The Riverstone Hotel Charleston-Sikeston is a top dog-friendly hotel, and offers a seasonal outdoor pool and laundry facilities for its human guests. Two other good options for you and your pet's trip include Super 8 by Wyndham Charleston/Sikeston East MO and Eagle Inn Charleston. See more pet-friendly hotel accommodations in Charleston.
What's the best accommodation near Lambert-St. Louis International Airport (STL)?
Marriott St. Louis Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.5 km) from Lambert-St. Louis Intl. Airport. Other good choices within close proximity to the airport include Pear Tree Inn Airport - St. Louis - St. Ann, MO and Drury Inn & Suites St. Louis Airport.
How is it to stay in Charleston?
Visitors to Charleston are sure to enjoy the restaurants. Tourists can also enjoy the city's entertainment choices, theaters, and churches. In Charleston, there are 3 hotels and other accommodations to choose from. Find out more about Charleston.
What are the top places to visit in Charleston?
The picturesque setting of Mississippi River and Ohio River exemplify the area's natural beauty. You'll also find Columbus-Belmont State Park and Fort Defiance State Park in the area. Check out what more to see and do in Expedia's Charleston guide.
What's the seasonal weather like in Charleston?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Charleston is 59 inches.

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