Mississippi County Vacation Rentals from ￥22,364: Search Short-Term Rentals

A bridge over a muddy river with green trees and hills in the background.

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Our top choices for Mississippi County vacation rentals

1. Spacious, secluded 4-bedroom house, just minutes from Reelfoot Lake State Park

Hornbeak

￥35,277 total

includes taxes & fees

Aug 12 - Aug 13

2. Peaceful secluded cabin located near Horseshoe Lake

Miller City

George B.

￥34,440 total

includes taxes & fees

Sep 9 - Sep 10

Coffee/tea maker, fridge, microwave, stovetop

3. Quiet Country Stay: Modern Home Near Paducah

Cunningham

Sheila C.

￥47,397 total

includes taxes & fees

Aug 17 - Aug 18

4. Cozy cabins on beautiful Horseshoe Lake

Olive Branch

Matthew

￥22,364 total

includes taxes & fees

Aug 12 - Aug 13

Coffee/tea maker, fridge, microwave, oven

5. Charming Home just minutes from Interstate and Mall

Kevil

Deannena H.

￥33,054 total

includes taxes & fees

Aug 30 - Aug 31

6. Vacation rental attached to our house out in the country.

Union City

Sherrie S.

￥23,664 total

includes taxes & fees

Sep 7 - Sep 8

7. The Rested Duck Mallard Room

Olive Branch

John S.

￥22,364 total

includes taxes & fees

Aug 12 - Aug 13

8. Quiet Country Stay: Modern Home Near Paducah

Cunningham

￥46,259 total

includes taxes & fees

Aug 17 - Aug 18

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Top Mississippi County Hotel Reviews

Duck Hunting, Fishing or Relaxing Family Vacation

10/10 Excellent

"This property was one of the cleanest we have ever stayed at. They had one of the nicest coffee stations I have ever seen in a VRBO and everything you could need !"

The Riverstone Hotel Charleston-Sikeston

8/10 Good

"The ad and picture for the hotel is a little deceiving. It shows a large fountain in front of the front lobby. There was none. This is the former Quality Inn Hotel was not good at all. The hotel has been cleaned up and rebranded. The room was nice. My only concern was all the bugs that were outside the room door and flew into the room when you opened your door at night. The other thing that I did not like was the surprise $100 fee that I had to pay up front for potential damage to the room. This fee was returned during check out."

Hampton Inn Sikeston

8/10 Good

"Hotel was nice but unfortunately someone decided to smoke in the elevator one night which made it shut down. So, until the repair was completed, everyone one the upper floors had to take the stairs down multiple floors. Usually not that big of an issue, but we were there for a bike ride and had to carry our bikes down three floors in the morning. Thankfully the elevator was fixed by the time we got back. Not really anything the hotel or staff caused, but just repercussions from the act of one person doing something stupid! We will definitely stay here again"

Peaceful secluded cabin located near Horseshoe Lake

10/10 Excellent

"We had a great stay at this cabin. This was a dreamy cabin, cozy, and quiet within beautiful nature. The town was small and cute to enjoy local stuff. The hosts were very nice and friendly and give us really good suggestions to enjoy our stay. Very clean, nicely designed, and accessible. Staying in this cabin is a must if you are in the neighborhood."

Find out more about Mississippi County

Vacation Apartments in Mississippi County

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Room 1

Change your mind

Treat yourself

Be picky

Our top choices for Mississippi County vacation rentals

1. Spacious, secluded 4-bedroom house, just minutes from Reelfoot Lake State Park

2. Peaceful secluded cabin located near Horseshoe Lake

3. Quiet Country Stay: Modern Home Near Paducah

4. Cozy cabins on beautiful Horseshoe Lake

5. Charming Home just minutes from Interstate and Mall

6. Vacation rental attached to our house out in the country.

7. The Rested Duck Mallard Room

8. Quiet Country Stay: Modern Home Near Paducah

9. Tiny house on the lake with tv free internet walk shower

10. Welcoming 4-bedroom house with AC in charming La Center

11. Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge

12. Come and relax at the Refuge at beautiful Reelfoot Lake!

13. The Hut. Cozy 2-bedroom mobile home on peaceful Reelfoot Lake with boat shed

14. Charming 3-bedroom house with free wifi and coffee it is close to the lake

15. Fish cleaning station, screened porch, covered front porch, fire pit, 3 BR

16. 3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters

17. Sunkist beach house. Lake side house 3 bedroom house

18. Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!

19. 3-bedroom house in charming Tiptonville with cool AC and washer and dryer

20. The Hut II on Reelfoot Lake

Find vacation rentals that suit your style

Top Mississippi County Hotel Reviews

Duck Hunting, Fishing or Relaxing Family Vacation

The Riverstone Hotel Charleston-Sikeston

Hampton Inn Sikeston

Sleep Inn at Discovery Park of America

Super 8 by Wyndham Charleston/Sikeston East MO

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Best Western Plus Sikeston I-55

Comfort Inn & Suites Sikeston I-55

Peaceful secluded cabin located near Horseshoe Lake

Find out more about Mississippi County

Vacation Apartments in Mississippi County

Vacation Rentals in Mississippi County

Change your mind

Treat yourself

Be picky

Our top choices for Mississippi County vacation rentals

1. Spacious, secluded 4-bedroom house, just minutes from Reelfoot Lake State Park

2. Peaceful secluded cabin located near Horseshoe Lake

3. Quiet Country Stay: Modern Home Near Paducah

4. Cozy cabins on beautiful Horseshoe Lake

5. Charming Home just minutes from Interstate and Mall

6. Vacation rental attached to our house out in the country.

7. The Rested Duck Mallard Room

8. Quiet Country Stay: Modern Home Near Paducah

9. Tiny house on the lake with tv free internet walk shower

10. Welcoming 4-bedroom house with AC in charming La Center

11. Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge

12. Come and relax at the Refuge at beautiful Reelfoot Lake!

13. The Hut. Cozy 2-bedroom mobile home on peaceful Reelfoot Lake with boat shed

14. Charming 3-bedroom house with free wifi and coffee it is close to the lake

15. Fish cleaning station, screened porch, covered front porch, fire pit, 3 BR

16. 3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters

17. Sunkist beach house. Lake side house 3 bedroom house

18. Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!

19. 3-bedroom house in charming Tiptonville with cool AC and washer and dryer

20. The Hut II on Reelfoot Lake

Find vacation rentals that suit your style

Top Mississippi County Hotel Reviews

Duck Hunting, Fishing or Relaxing Family Vacation

Find out more about Mississippi County

Vacation Apartments in Mississippi County