
Find hotels in Central San Diego, CA from ¥12,882
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Central San Diego hotels

Lafayette Hotel & Club
Lafayette Hotel & ClubUniversity Heights
9.2 out of 10, Wonderful, (1,564 reviews)
The price is ¥39,758
¥45,701 total
includes taxes & fees
Apr 6 - Apr 7

Kings Inn San Diego
Kings Inn San DiegoMission Valley
8.8 out of 10, Excellent, (3,656 reviews)
The price is ¥14,542
¥16,687 total
includes taxes & fees
Apr 6 - Apr 7

Hilton Garden Inn San Diego Old Town/SeaWorld Area
Hilton Garden Inn San Diego Old Town/SeaWorld AreaOld Town San Diego
8.8 out of 10, Excellent, (1,388 reviews)
The price is ¥23,357
¥26,849 total
includes taxes & fees
Apr 12 - Apr 13

Holiday Inn Express San Diego Airport - Old Town by IHG
Holiday Inn Express San Diego Airport - Old Town by IHGMission Hills
9.2 out of 10, Wonderful, (1,059 reviews)
The price is ¥22,513
¥25,878 total
includes taxes & fees
Apr 12 - Apr 13

Old Town Western Inn & Suites
Old Town Western Inn & SuitesOld Town San Diego
7.6 out of 10, Good, (1,005 reviews)
The price is ¥15,201
¥17,139 total
includes taxes & fees
Apr 6 - Apr 7

HYATT house San Diego/Sorrento Mesa
HYATT house San Diego/Sorrento MesaSorrento Valley
9.0 out of 10, Wonderful, (1,002 reviews)
The price is ¥24,270
¥27,897 total
includes taxes & fees
May 3 - May 4

Hyatt Regency La Jolla
Hyatt Regency La JollaUniversity City
8.8 out of 10, Excellent, (1,009 reviews)
The price is ¥24,825
¥34,435 total
includes taxes & fees
Apr 6 - Apr 7

Pleasant Inn
Pleasant InnClairemont
8.6 out of 10, Excellent, (1,359 reviews)
The price is ¥14,929
¥17,131 total
includes taxes & fees
Apr 12 - Apr 13

Best Western Plus Hacienda Hotel Old Town
Best Western Plus Hacienda Hotel Old TownOld Town San Diego
8.4 out of 10, Very Good, (1,944 reviews)
The price is ¥21,413
¥24,613 total
includes taxes & fees
Apr 26 - Apr 27

Comfort Inn San Diego Old Town
Comfort Inn San Diego Old TownOld Town San Diego
8.2 out of 10, Very Good, (2,007 reviews)
The price is ¥18,865
¥21,685 total
includes taxes & fees
Apr 26 - Apr 27

Crowne Plaza San Diego - Mission Valley by IHG
Crowne Plaza San Diego - Mission Valley by IHGMission Valley
8.0 out of 10, Very Good, (1,015 reviews)
The price is ¥18,841
¥21,715 total
includes taxes & fees
Apr 13 - Apr 14

Hampton Inn San Diego-Kearny Mesa
Hampton Inn San Diego-Kearny MesaKearny Mesa
9.2 out of 10, Wonderful, (1,006 reviews)
The price is ¥20,163
¥23,137 total
includes taxes & fees
Apr 12 - Apr 13

Courtyard by Marriott San Diego Central
Courtyard by Marriott San Diego CentralKearny Mesa
8.6 out of 10, Excellent, (1,003 reviews)
The price is ¥20,687
¥23,778 total
includes taxes & fees
Apr 26 - Apr 27

Four Points by Sheraton San Diego
Four Points by Sheraton San DiegoKearny Mesa
8.2 out of 10, Very Good, (1,004 reviews)
The price is ¥18,322
¥21,061 total
includes taxes & fees
May 6 - May 7

Best Western San Diego/Miramar Hotel
Best Western San Diego/Miramar HotelMiramar
7.8 out of 10, Good, (1,260 reviews)
The price is ¥17,302
¥19,888 total
includes taxes & fees
Apr 6 - Apr 7

Courtyard by Marriott San Diego Sorrento Valley
Courtyard by Marriott San Diego Sorrento ValleySorrento Valley
8.8 out of 10, Excellent, (1,001 reviews)
The price is ¥22,833
¥26,289 total
includes taxes & fees
Apr 12 - Apr 13

California Suites Hotel
California Suites HotelClairemont
7.8 out of 10, Good, (2,437 reviews)
The price is ¥14,226
¥16,324 total
includes taxes & fees
Apr 12 - Apr 13

Homewood Suites by Hilton San Diego Central
Homewood Suites by Hilton San Diego CentralScripps Ranch
8.6 out of 10, Excellent, (884 reviews)
The price is ¥18,199
¥20,919 total
includes taxes & fees
Apr 19 - Apr 20

Berkshire Motor Hotel
Berkshire Motor HotelNorth Park
8.4 out of 10, Very Good, (1,006 reviews)
The price is ¥15,074
¥16,996 total
includes taxes & fees
Apr 6 - Apr 7

Cosmopolitan Hotel & Restaurant
Cosmopolitan Hotel & RestaurantOld Town San Diego
9.0 out of 10, Wonderful, (713 reviews)
The price is ¥24,286
¥27,382 total
includes taxes & fees
Apr 6 - Apr 7
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Vacation Rentals in Central San Diego
Aparthotel

Uptown Inn by Vantaggio - Limited Service Apart-Hotel
Uptown Inn by Vantaggio - Limited Service Apart-HotelHillcrest
8.4 out of 10, Very Good, (330 reviews)
Save an average of 15% on thousands of hotels when you're signed in
Top Central San Diego Hotel Reviews
Hotels in Central San Diego with star-rating
Explore a world of travel with Expedia
- Cheap Hotels in Old Town San Diego
- Ski Hotels in Mission Valley
- Rv Parks in Mission San Diego Station
- Mission Valley Hotels
- Torrey Pines Hotels
- Cheap Hotels in La Jolla
- Houseboats in La Jolla
- Farmstay in Fiesta Island
- North Pacific Beach Hotels
- Resorts & Hotels with Spas in La Jolla
- Luxury Hotels in Kearny Mesa
- Residences in La Jolla
- Residences in Central San Diego
- Winery Hotels in Central San Diego
- Mira Mesa Hotels
- Hostels in La Jolla
- Adventure Hotels in La Jolla Village
- Beach Hotels in Mission Valley
- Hillcrest Hotels
- Business Hotels in Kearny Mesa
- Hotels near Westfield UTC
- Family Hotels in Linda Vista
- Hotels near Birch Aquarium
- Hotels near Mission San Diego Station
- Hotels near University of San Diego
- Cheap Hotels in Mira Mesa
- Cheap Hotels in Hillcrest
- Luxury Hotels in La Jolla
- Resorts & Hotels with Spas in Miramar
- La Jolla Shores Hotels
- Hotels near Marine Corps Air Station Miramar
- Family Hotels in San Carlos
- Apartments in Fenton Parkway Station
- Kearny Mesa Hotels
- Clairemont Hotels
- Cheap Hotels in Sorrento Valley
- Cheap Hotels in Torrey Pines
- Palaces in La Jolla
- Family Hotels in La Jolla Village
- Hotels near University of California
- Resorts in Fiesta Island
- All-Inclusive Hotel Hotels in Pacific Beach
- Shopping Hotels in Mission Valley
- Rv Parks in Central San Diego
- Boutique Hotels in Torrey Pines
- Romantic Hotels in La Jolla
- Cheap Hotels in City Heights
- Cheap Hotels in Central San Diego
- Village of La Jolla Hotels
- Golf Hotels in Torrey Pines
- Beach Hotels in Village of La Jolla
- Clairemont Mesa Hotels
- La Jolla Village Hotels
- Clairemont Mesa East Hotels
- Miramar Hotels
- Villas in La Jolla
- Cheap Hotels in Central Mission Beach
- Luxury Hotels in Pacific Beach
- Scripps Ranch Hotels
- Pet-Friendly Hotels in Central San Diego
- Luxury Hotels in North Park
- Beach Hotels in Pacific Beach
- Hotels near Mission Valley Mall
- Boutique Hotels in La Jolla Village
- Pet-Friendly Hotels in Miramar
- Cheap Hotels in University City
- Linda Vista Hotels
- Hotels near Fashion Valley Mall
- Hotels near Convoy District
- Luxury Hotels in Miramar
- Cheap Hotels in Mission Beach
- Boutique Hotels in Little Italy
- Sorrento Valley Hotels
- Rv Parks in North Central San Diego
- Pet-Friendly Hotels in Mission Valley
- Hotels near Hotel Circle
- Cheap Hotels in La Jolla Shores
- Luxury Hotels in La Jolla Shores
- Pousadas in La Jolla
- Cheap Hotels in Kearny Mesa
- Resorts in La Jolla
- Ski Hotels in Mira Mesa
- All-Inclusive Hotel Hotels in Mission Valley
- Luxury Hotels in Serra Mesa
- University City Hotels
- Luxury Hotels in Mira Mesa
- Resorts in San Diego Coaster Sorrento Valley Station
- Ski Hotels in North Park
- All-Inclusive Hotel Hotels in Bay Park
- Hotels near Montgomery Field
- Business Hotels in Old Town San Diego
- Hotels near Black's Beach
- Aparthotels in Central San Diego
- Guest Houses in La Jolla
- Hotels near La Jolla Cove
- Condo Resorts in Central San Diego



















































































