A public park with a fountain featuring bronze sculptures of mythological figures, surrounded by trees and a large building in the background.

Find 5 Star Hotels in Downtown St. Louis, MO from ￥25,220

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Downtown St. Louis 5 Star Hotels

Our top choices for Downtown St. Louis 5-star hotels

Terrace/patio

1. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,001 reviews)
"The absolute best place to stay in St Louis."
United States
Brandy
The price is ￥59,801
￥69,924 total
includes taxes & fees
Aug 16 - Aug 17
Four Seasons Hotel St Louis
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Downtown St. Louis.
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

315 Chestnut St St. Louis MO
The price is ￥21,385 per night from Aug 15 to Aug 16
￥21,385
￥25,220 total
Aug 15 - Aug 16
includes taxes & fees
8.6/10 Excellent! (4,170 reviews)
Still don't see what you're looking for?
See all properties in Downtown St. Louis.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Downtown St. Louis Hotel Reviews

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

10/10 Excellent
"Loved it"
Maggie 1-night trip
Posted 2 days ago
Four Seasons Hotel St Louis

Frequently asked questions

What are the best 5-star hotels in Downtown St. Louis?
Enjoy top-class amenities and the highest level of service at Four Seasons Hotel St Louis. Located around the St. Louis neighborhood of Downtown St. Louis, this 5-star hotel is the preferred choice for many based on reviews by our customers.
How much does it cost to stay in a 5-star hotel in Downtown St. Louis?
How much you pay for a 5-star hotel in Downtown St. Louis can vary according to when you decide to travel and how long you plan to stay, among a number of factors. Take advantage of our price per night filter and other search tools to score the best deal on a high-end getaway.

  • Search for the lowest price per night from ￥25,220

What makes a hotel 5 stars in Downtown St. Louis?
In Downtown St. Louis, a hotel must provide a specific level of high-end amenities to be designated 5 stars. These may include gourmet restaurants, on-site gyms, saunas and spas, complimentary luxury toiletries, premium bedding and more. What also sets 5-star hotels apart is their superior standard of service. You can look forward to things like nightly turn-down services, concierge services and in-room massages. Some may even offer additional touches like a welcome gift.