Find 4 Star Hotels in Central San Diego, CA from ¥19,648

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Central San Diego 4 Star Hotels

This weekend
Next weekend

Compare Central San Diego 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

DoubleTree by Hilton Hotel San Diego - Mission Valley

4.0 star property
Mission Valley
8.4 out of 10, Very Good, (1376)
"Great hotel in a great area - would definitely stay here again."
United States
Bhupinder
The price is ¥17,093
¥19,648 total
includes taxes & fees
Dec 18 - Dec 19
DoubleTree by Hilton Hotel San Diego - Mission Valley

Hilton San Diego Mission Valley

4.0 star property
Mission Valley
8.0 out of 10, Very Good, (2218)
"Very good place to stay at"
Canada
Shan
The price is ¥18,379
¥21,125 total
includes taxes & fees
Dec 23 - Dec 24
Hilton San Diego Mission Valley

Legacy Resort Hotel & Spa

4.0 star property
Mission Valley
9.2 out of 10, Wonderful, (2987)
"Friendly, staff was very helpful, great size rooms, and over all was an amazing stay"
United States
Naya
The price is ¥23,668
¥27,205 total
includes taxes & fees
Dec 11 - Dec 12
Legacy Resort Hotel & Spa

Lafayette Hotel & Club

4.0 star property
University Heights
9.4 out of 10, Exceptional, (1309)
"Loved everything, I could stay there forever"
United States
Mariana
The price is ¥35,157
¥40,343 total
includes taxes & fees
Dec 15 - Dec 16
Lafayette Hotel & Club

Sheraton Mission Valley San Diego Hotel

4.0 star property
Mission Valley
8.6 out of 10, Excellent, (1643)
"The room was a great size and super clean, the staff is super nice "
United States
Ligia
The price is ¥18,356
¥21,099 total
includes taxes & fees
Dec 11 - Dec 12
Sheraton Mission Valley San Diego Hotel

Embassy Suites by Hilton San Diego La Jolla

4.0 star property
University City
8.8 out of 10, Excellent, (1777)
"Very pleasant area!!! Nice hotel"
United States
Yvette
The price is ¥23,521
¥27,037 total
includes taxes & fees
Dec 18 - Dec 19
Embassy Suites by Hilton San Diego La Jolla

San Diego Marriott Mission Valley

4.0 star property
Mission Valley
8.8 out of 10, Excellent, (1015)
"Great location, hotel is under construction so part of the hotel is completely closed off for construction. "
United States
Amama
The price is ¥19,702
¥22,647 total
includes taxes & fees
Dec 15 - Dec 16
San Diego Marriott Mission Valley

Hyatt Regency La Jolla

4.0 star property
University City
8.8 out of 10, Excellent, (1002)
"Clean rooms, excellent staff and Drift restaurant is also very nice "
United States
Paresh
The price is ¥22,376
¥31,479 total
includes taxes & fees
Dec 14 - Dec 15
Hyatt Regency La Jolla

San Diego Marriott La Jolla

4.0 star property
University City
8.6 out of 10, Excellent, (2156)
"Very nice hotel and clean rooms"
United States
Noor
The price is ¥25,384
¥29,206 total
includes taxes & fees
Jan 3 - Jan 4, 2026
San Diego Marriott La Jolla

DoubleTree by Hilton San Diego - Hotel Circle

4.0 star property
Mission Valley
7.4 out of 10, Good, (1764)
"Very comfortable stay. "
United States
Rosa
The price is ¥18,379
¥21,125 total
includes taxes & fees
Dec 29 - Dec 30
DoubleTree by Hilton San Diego - Hotel Circle

Town and Country San Diego

4.0 star property
Mission Valley
8.6 out of 10, Excellent, (1316)
"Great place for family "
United States
Leslie
The price is ¥22,961
¥31,762 total
includes taxes & fees
Dec 4 - Dec 5
Town and Country San Diego

City24 Hotel Little Italy Mission Hills

4.5 star property
Middletown
9.6 out of 10, Exceptional, (102)
"would definitely go back and stay there again "
United States
Kounwick
City24 Hotel Little Italy Mission Hills

Residence Inn by Marriott San Diego Mission Valley

4.5 star property
Mission Valley
8.8 out of 10, Excellent, (1000)
"It was spacious and convenient but it was very dirty"
United States
Kabnne
Residence Inn by Marriott San Diego Mission Valley

15 Min driving to La Jolla Shore, Del Mar Beach, Torrey Pines State Reserve, UC

4.0 star property
University City
8.0 out of 10, Very Good, (1)
"Nice place to relax and well equipped. The property manager welcomed us with wine and made sure we had everything we needed. Brought patio umbrella, new dishes, glasses and silver ware. The mall and canyon for long walks is 5 min away. Less then 7 minute drive to the beach. Loved our stay."
United States
Ami Z.
15 Min driving to La Jolla Shore, Del Mar Beach, Torrey Pines State Reserve, UC
Save an average of 15% on thousands of hotels when you're signed in

Learn more about Central San Diego

Explore the seaside area of Central San Diego—a zoo, sports teams, and popular sights like San Diego Zoo.

San Diego, California cityscape at the Gaslamp Quarter.; Shutterstock ID 446681584

Top Central San Diego Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Central San Diego?
Expedia can help you easily locate the ideal 4-star hotel for your vacation in Central San Diego. Use our filter tool to tailor your search by things like price, conveniences and hotel star rating and get access to terrific deals in a couple of clicks.

  • Search for the lowest price from ¥19,648

What's the difference between 5-star and 4-star hotels in Central San Diego?
Offering a welcoming guest experience and upscale surroundings, 4-star hotels are a wonderful option for your Central San Diego escape. These kinds of stays generally feature loads of handy amenities that make it easy to unpack and unwind — think complimentary bathrobes, restaurants and pools. Or live in the lap of luxury at a 5-star hotel designed to spoil you with high-end perks and amenities. A personalized service, complimentary toiletries and gourmet dining are typically featured at these plush retreats.
Does Central San Diego have any 4-star all-inclusive resorts?
Finding your dream resort in Central San Diego is as simple as entering your travel dates and selecting our "All inclusive" filter. Stay and play where everything is already taken care of like your accommodations, food, activities and entertainment, or choose a standard 4-star resort in or around this leading destination.

Explore a world of travel with Expedia