Find 4 Star Hotels in Central San Diego, CA from ￥21,135

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Check availability on Central San Diego 4 Star Hotels

Our top choices for Central San Diego 4-star hotels

Daily buffet breakfast for a fee
DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley
4.0 star property
Mission Valley
8.4 out of 10, Very Good, (1410)
"Great hotel in a great area - would definitely stay here again."
United States
Bhupinder
The price is ￥18,398
￥21,148 total
includes taxes & fees
Jan 4 - Jan 5, 2026
DoubleTree by Hilton Hotel San Diego - Mission Valley
Lobby
Hilton San Diego Mission Valley

Hilton San Diego Mission Valley

Hilton San Diego Mission Valley
4.0 star property
Mission Valley
8.0 out of 10, Very Good, (2246)
"Excelente hotel"
Mexico
Julio
The price is ￥18,409
￥21,160 total
includes taxes & fees
Dec 21 - Dec 22
Hilton San Diego Mission Valley
Garden
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
4.0 star property
Mission Valley
9.2 out of 10, Wonderful, (2951)
"Everything was super comfortable and the room was surprisingly affordable for the amenities you get. We will definitely stay there again if we go to San Diego."
United States
Eric
The price is ￥23,706
￥27,249 total
includes taxes & fees
Dec 16 - Dec 17
Legacy Resort Hotel & Spa
Outdoor pool, open 7:00 AM to 9:00 PM, cabanas (surcharge)
Lafayette Hotel & Club

Lafayette Hotel & Club

Lafayette Hotel & Club
4.0 star property
University Heights
9.4 out of 10, Exceptional, (1336)
"My wife loved everything about this vintage hotel."
United States
Eddie
The price is ￥35,680
￥40,943 total
includes taxes & fees
Dec 29 - Dec 30
Lafayette Hotel & Club
Outdoor pool
Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel
4.0 star property
Mission Valley
8.6 out of 10, Excellent, (1662)
"I really enjoyed the stay. Staff was really awesome"
United States
Glen
The price is ￥18,386
￥21,135 total
includes taxes & fees
Dec 21 - Dec 22
Sheraton Mission Valley San Diego Hotel
Terrace/patio
Embassy Suites by Hilton San Diego La Jolla

Embassy Suites by Hilton San Diego La Jolla

Embassy Suites by Hilton San Diego La Jolla
4.0 star property
University City
8.8 out of 10, Excellent, (1781)
"Good hot food!!"
United States
Cris
The price is ￥24,805
￥28,512 total
includes taxes & fees
Dec 21 - Dec 22
Embassy Suites by Hilton San Diego La Jolla
Property amenity
San Diego Marriott Mission Valley

San Diego Marriott Mission Valley

San Diego Marriott Mission Valley
4.0 star property
Mission Valley
8.8 out of 10, Excellent, (1011)
"Great room and staff"
United States
Mario
The price is ￥21,658
￥24,895 total
includes taxes & fees
Dec 22 - Dec 23
San Diego Marriott Mission Valley
Outdoor pool, sun loungers
Hyatt Regency La Jolla

Hyatt Regency La Jolla

Hyatt Regency La Jolla
4.0 star property
University City
8.8 out of 10, Excellent, (1006)
"Check in was great, employees were so nice"
United States
Noel
The price is ￥23,699
￥32,998 total
includes taxes & fees
Dec 19 - Dec 20
Hyatt Regency La Jolla
Outdoor pool
San Diego Marriott La Jolla

San Diego Marriott La Jolla

San Diego Marriott La Jolla
4.0 star property
University City
8.6 out of 10, Excellent, (2180)
"We had a great stay! Everything was clean and the staff was phenomenal!! "
United States
Mattie
The price is ￥24,147
￥27,786 total
includes taxes & fees
Jan 10 - Jan 11, 2026
San Diego Marriott La Jolla
Terrace/patio
DoubleTree by Hilton San Diego - Hotel Circle

DoubleTree by Hilton San Diego - Hotel Circle

DoubleTree by Hilton San Diego - Hotel Circle
4.0 star property
Mission Valley
7.4 out of 10, Good, (1774)
"Friendly staff, great value for the price."
United States
Bertha
The price is ￥18,409
￥21,160 total
includes taxes & fees
Dec 21 - Dec 22
DoubleTree by Hilton San Diego - Hotel Circle
2 outdoor pools, a heated pool, cabanas (surcharge), sun loungers
Town and Country San Diego

Town and Country San Diego

Town and Country San Diego
4.0 star property
Mission Valley
8.6 out of 10, Excellent, (1324)
"Clean room, friendly staff."
United States
Gail
The price is ￥22,382
￥31,104 total
includes taxes & fees
Dec 16 - Dec 17
Town and Country San Diego
Exterior
City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.6 out of 10, Exceptional, (106)
"would definitely go back and stay there again "
United States
Kounwick
City24 Hotel Little Italy Mission Hills
BBQ/picnic area
Residence Inn by Marriott San Diego Mission Valley

Residence Inn by Marriott San Diego Mission Valley

Residence Inn by Marriott San Diego Mission Valley
4.5 star property
Mission Valley
8.8 out of 10, Excellent, (1000)
"It was spacious and convenient but it was very dirty"
United States
Kabnne
Residence Inn by Marriott San Diego Mission Valley
Outdoor pool, a heated pool
15 Min driving to La Jolla Shore, Del Mar Beach, Torrey Pines State Reserve, UC

15 Min driving to La Jolla Shore, Del Mar Beach, Torrey Pines State Reserve, UC

15 Min driving to La Jolla Shore, Del Mar Beach, Torrey Pines State Reserve, UC
4.0 star property
University City
8.0 out of 10, Very Good, (1)
"Nice place to relax and well equipped. The property manager welcomed us with wine and made sure we had everything we needed. Brought patio umbrella, new dishes, glasses and silver ware. The mall and canyon for long walks is 5 min away. Less then 7 minute drive to the beach. Loved our stay."
United States
Ami Z.
15 Min driving to La Jolla Shore, Del Mar Beach, Torrey Pines State Reserve, UC
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Learn more about Central San Diego

Explore the seaside area of Central San Diego—a zoo, sports teams, and popular sights like San Diego Zoo.

See all hotels in Central San Diego
San Diego, California cityscape at the Gaslamp Quarter.; Shutterstock ID 446681584

Top Central San Diego Hotel Reviews

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

10/10 Excellent
"Very well and clean "
Silvia 1-night trip
Posted 2 days ago
Legacy Resort Hotel & Spa

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Central San Diego?
Expedia can help you easily locate the ideal 4-star hotel for your vacation in Central San Diego. Use our filter tool to tailor your search by things like price, conveniences and hotel star rating and get access to terrific deals in a couple of clicks.

  • Search for the lowest price from ￥21,135

What's the difference between 5-star and 4-star hotels in Central San Diego?
Offering a welcoming guest experience and upscale surroundings, 4-star hotels are a wonderful option for your Central San Diego escape. These kinds of stays generally feature loads of handy amenities that make it easy to unpack and unwind — think complimentary bathrobes, restaurants and pools. Or live in the lap of luxury at a 5-star hotel designed to spoil you with high-end perks and amenities. A personalized service, complimentary toiletries and gourmet dining are typically featured at these plush retreats.
Does Central San Diego have any 4-star all-inclusive resorts?
Finding your dream resort in Central San Diego is as simple as entering your travel dates and selecting our "All inclusive" filter. Stay and play where everything is already taken care of like your accommodations, food, activities and entertainment, or choose a standard 4-star resort in or around this leading destination.

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