Photo by Southernmost Illinois Tourism Bureau

Find hotels in Southern Illinois, IL from ¥7,535

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Compare 1,053 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Drury Plaza Hotel Mt. Vernon

3.0 star property
9.6 out of 10, Exceptional, (1413)
"Very nice staff and great place to stay"
The price is ¥13,886
¥15,705 total
includes taxes & fees
Aug 31 - Sep 1
Drury Plaza Hotel Mt. Vernon

Drury Inn & Suites Marion

3.0 star property
9.4 out of 10, Exceptional, (1004)
"This hotel was excellent! Clean and friendly staff "
The price is ¥9,602
¥11,521 total
includes taxes & fees
Aug 31 - Sep 1
Drury Inn & Suites Marion

SureStay Hotel by Best Western Whittington Rend Lake

2.5 star property
8.8 out of 10, Excellent, (844)
"Very good place to stay"
The price is ¥9,971
¥11,066 total
includes taxes & fees
Aug 18 - Aug 19
SureStay Hotel by Best Western Whittington Rend Lake

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

2.5 star property
9.4 out of 10, Exceptional, (462)
"Staff was very friendly, and the room was clean, and cozy, with the bed being very comfortable!"
The price is ¥15,365
¥17,052 total
includes taxes & fees
Aug 17 - Aug 18
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

The Principal Hotel

3.5 star property
9.8 out of 10, Exceptional, (116)
"Perfect stay! "
The price is ¥15,500
¥17,202 total
includes taxes & fees
Aug 21 - Aug 22
The Principal Hotel

Country Inn & Suites by Radisson, Effingham, IL

2.5 star property
8.8 out of 10, Excellent, (1005)
"We had a very nice stay."
The price is ¥15,291
¥16,969 total
includes taxes & fees
Aug 14 - Aug 15
Country Inn & Suites by Radisson, Effingham, IL

Eighteen-Ninety Sleepover

2.5 star property
9.6 out of 10, Exceptional, (291)
"Beautiful restored small hotel,adorable small town ,very walkable to coffee shop,restaurants and ice cream ."
The price is ¥16,157
¥18,092 total
includes taxes & fees
Aug 24 - Aug 25
Eighteen-Ninety Sleepover

Super 8 by Wyndham Grayville

2.0 star property
8.2 out of 10, Very Good, (441)
"Very calm and quiet stay and close to the Garden of Gods park"
The price is ¥10,674
¥11,312 total
includes taxes & fees
Aug 20 - Aug 21
Super 8 by Wyndham Grayville

Harrah's Metropolis Hotel & Casino

3.5 star property
8.4 out of 10, Very Good, (1005)
"Great stay"
The price is ¥13,688
¥17,556 total
includes taxes & fees
Aug 17 - Aug 18
Harrah's Metropolis Hotel & Casino

Cobblestone Inn & Suites - Altamont

2.5 star property
9.6 out of 10, Exceptional, (746)
"Always a great place with comfortable rooms."
Cobblestone Inn & Suites - Altamont

Best Western Marion Hotel

2.5 star property
8.2 out of 10, Very Good, (1001)
"Clean room - nice accessible shower - firm but comfortable bed - decent breakfast options."
The price is ¥10,165
¥12,195 total
includes taxes & fees
Aug 24 - Aug 25
Best Western Marion Hotel

Drury Inn & Suites St. Louis Collinsville

3.0 star property
9.6 out of 10, Exceptional, (1007)
"Great place to stay "
The price is ¥15,659
¥18,005 total
includes taxes & fees
Aug 17 - Aug 18
Drury Inn & Suites St. Louis Collinsville

Economy Inn & Suites

2.0 star property
8.0 out of 10, Very Good, (54)
"The staff was awesome. The room nice and clean But you guys could work on what the outside looks like All and all it was a great stay. Would stay again "
The price is ¥10,342
¥11,477 total
includes taxes & fees
Aug 15 - Aug 16
Economy Inn & Suites

Baymont by Wyndham Marion

2.5 star property
8.4 out of 10, Very Good, (1037)
"Just stayed 1 night Very good 👍 "
The price is ¥11,967
¥14,357 total
includes taxes & fees
Aug 24 - Aug 25
Baymont by Wyndham Marion

Best Western Plus Parkside Inn & Suites

2.5 star property
9.8 out of 10, Exceptional, (292)
"Very clean, quiet and friendly stay"
The price is ¥16,883
¥18,736 total
includes taxes & fees
Sep 7 - Sep 8
Best Western Plus Parkside Inn & Suites

Hilton Garden Inn Mattoon, Il

3.0 star property
8.8 out of 10, Excellent, (174)
"Best accommodations in the area and pet friendly. "
The price is ¥19,967
¥22,159 total
includes taxes & fees
Aug 17 - Aug 18
Hilton Garden Inn Mattoon, Il

Days Inn & Suites by Wyndham Casey

2.0 star property
7.4 out of 10, Good, (760)
"Great location and a quite place to stay and relax "
The price is ¥9,573
¥10,625 total
includes taxes & fees
Sep 1 - Sep 2
Days Inn & Suites by Wyndham Casey

Walker's Bluff Casino Resort

4.5 star property
9.4 out of 10, Exceptional, (362)
"I would love to stay here again, shoutout to their beds!! "
Walker's Bluff Casino Resort

Quality Inn Effingham North

2.5 star property
8.4 out of 10, Very Good, (909)
"Great hotel. Will stay again. "
The price is ¥12,626
¥14,012 total
includes taxes & fees
Aug 18 - Aug 19
Quality Inn Effingham North

Cobblestone Hotel & Suites - Newton

2.5 star property
9.2 out of 10, Wonderful, (313)
"Clean, pet friendly, nice breakfast,nice bar area staff was helpful and friendly "
The price is ¥15,476
¥17,175 total
includes taxes & fees
Aug 19 - Aug 20
Cobblestone Hotel & Suites - Newton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Southern Illinois, IL

Showing deals for:Aug 22 - Aug 24
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Southern Illinois attractions

Southern Illinois University
Campus Lake at Southern Illinois University in Carbondale, IL.

Southern Illinois University

Take a campus tour or just explore the area of Southern Illinois University, during your trip to Carbondale. Check out the shops and top-notch restaurants in this family-friendly area.

Scott Air Force Base

Scott Air Force Base

After visiting Scott Air Force Base, make a plan to see the other sights and activities in Scott Air Force Base. Attend a sporting event in this family-friendly area.

DuQuoin State Fairgrounds

DuQuoin State Fairgrounds

Catch an event at DuQuoin State Fairgrounds during your trip to Du Quoin. Experience the area's festivals and live music.

Learn more about Southern Illinois

Discover the culture and history of this region shaped by indigenous and pioneering communities and spend time in its peaceful, picturesque landscapes.

Southern Illinois showing forest scenes, a sunset and landscape views
Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau

Top Southern Illinois Hotel Reviews