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Top Romantic Southeast Missouri Hotels

Historical 'Kage House' Short Term Rental located in "Old Town Cape"

Cape Girardeau MO

5 hours drive from Mark Twain National Forest

Whatever your love language might be, you and your special someone are sure to love the riverside location at this romantic apartment.

9.8/10 Exceptional! (173 reviews)

Great location, quality bedding and pillows, and other comfortable amenities for a short getaway in historic downtown Cape Girardeau. Excellent value!

Reviewed on Dec 15, 2025

Echo Bluff State Park

34489 Echo Bluff Dr Eminence MO

43 min drive from Mark Twain National Forest

Romance is in the air at this Art Deco hotel, featuring in-room fireplaces and onsite dining.

9.4/10 Exceptional! (221 reviews)

This entire trip was inspired by Tina, a staff member. I met Tina passing through the area and she provided me with a lot of information which gave me the idea to plan a weekend trip with my wife. The lodge room we had was clean and comfortable, My wife and I had a wonderful time exploring most of ...

Reviewed on Jan 19, 2026

See all 625 properties in Southeast Missouri

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.