Find hotels in Wykoff, MN from ￥9,129

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Dec 12 - Dec 13
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Dec 13 - Dec 14
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Our top choices for Wykoff hotels

Front of property
Stone Mill Hotel & Suites

Stone Mill Hotel & Suites

Stone Mill Hotel & Suites
3.0 star property
Lanesboro
9.2 out of 10, Wonderful, (661)
Experience outdoor adventure from this welcoming retreat offering hiking trails, kayaking and cross-country skiing nearby. Enjoy complimentary breakfast, WiFi and parking while staying minutes from Commonweal Theatre and Lanesboro Arts Center.
"Great service, location"
United States
Eric
The price is ￥16,326
￥17,531 total
includes taxes & fees
Dec 14 - Dec 15
Stone Mill Hotel & Suites
Loft | Iron/ironing board, free WiFi
Country Lodge inn

Country Lodge inn

Country Lodge inn
2.0 star property
Harmony
9.0 out of 10, Wonderful, (39)
Surrounded by Minnesota countryside, this welcoming lodge offers convenient access to Slim's Woodshed and Museum. Enjoy the tranquil setting with free WiFi and parking while exploring nearby Niagara Cave.
"Old motel but clean, with friendly owners."
United States
Fred
The price is ￥20,725
￥23,791 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Country Lodge inn
Deluxe Double Room | Down comforters, pillowtop beds, individually decorated
Country Trails Inn & Suites

Country Trails Inn & Suites

Country Trails Inn & Suites
2.0 star property
Preston
9.4 out of 10, Exceptional, (102)
Escape to this golf hotel in Preston featuring a charming winery. After a refreshing morning swim, relax in the hot tub. Free amenities include breakfast, WiFi, and parking. The Old Barn Resort Course is nearby.
"Great desk host, nice property, comfortable rooms, nice breakfast & dining room within walking from Casey’s gas & market. "
United States
Nancy
The price is ￥17,703
￥19,541 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Country Trails Inn & Suites
Front of property
White Valley Motel

White Valley Motel

White Valley Motel
2.5 star property
St. Charles
5.8 out of 10, (125)
Located in St. Charles, this welcoming motel offers free WiFi and parking with 24-hour front desk service. Enjoy easy access to the scenic Whitewater River while having a comfortable base for exploring the area.
"Very nice owner i wil come back again thank you.. "
United States
Rolando
The price is ￥10,729
￥11,965 total
includes taxes & fees
Dec 14 - Dec 15
White Valley Motel
Property entrance
Country Inn & Suites Rochester South Mayo Clinic

Country Inn & Suites Rochester South Mayo Clinic

Country Inn & Suites Rochester South Mayo Clinic
3.0 star property
Rochester
8.4 out of 10, Very Good, (1003)
Just a 10-minute drive from Mayo Clinic, this Rochester retreat features a relaxing hot tub, indoor pool, and fitness center. Guests appreciate the peaceful atmosphere, helpful staff, and convenient perks like free breakfast, WiFi, and parking.
"Clean room, fun staff."
United States
Thomas
The price is ￥15,067
￥17,345 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Country Inn & Suites Rochester South Mayo Clinic
Lobby
Americas Best Value Inn & Suites Spring Valley

Americas Best Value Inn & Suites Spring Valley

Americas Best Value Inn & Suites Spring Valley
2.0 star property
Spring Valley
8.2 out of 10, Very Good, (432)
Enjoy free morning meals and convenient parking at this well-maintained property. Work out in the fitness center after exploring nearby Masonic Park and Four Daughters Vineyard & Winery. Clean rooms and business-friendly amenities create a comfortable base for your stay.
"Breakfast was fresh and plentiful. The service was amazing. We always stay here when we come to Spring Valley to meet family. We really enjoy this hotel. We had three rooms this time and they were great"
United States
Carol
The price is ￥12,284
￥13,558 total
includes taxes & fees
Dec 14 - Dec 15
Americas Best Value Inn & Suites Spring Valley
BBQ/picnic area
Aspen Suites

Aspen Suites

Aspen Suites
3.0 star property
Rochester
9.0 out of 10, Wonderful, (688)
Just 5 minutes from Mayo Clinic, this hotel offers a relaxing indoor pool and hot tub after a long day. Enjoy free breakfast, WiFi, and parking while the attentive staff ensures a stress-free stay near Kutzky Park Tennis Center.
"I always stay at this hotel , love it clean comfortable rooms, they gave us vouchers for 4 free meals for Thanksgiving dinner"
United States
Cindy
The price is ￥24,099
￥29,131 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Aspen Suites
Lunch and dinner served, American cuisine
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
3.0 star property
Historic Southwest
8.6 out of 10, Excellent, (1002)
This quiet hotel offers convenience with an indoor pool and 24-hour fitness center. A quick walk to Mayo Clinic and hospital, guests love the helpful staff and American cuisine at Twigs Tavern. Free breakfast, parking, and WiFi enhance your Rochester stay.
"The room was clean, the staff was very friendly and helpful."
United States
kenneth
The price is ￥19,156
￥22,053 total
includes taxes & fees
Dec 20 - Dec 21
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Terrace/patio
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
3.0 star property
Kutzky Park
9.2 out of 10, Wonderful, (476)
Located minutes from Mayo Clinic, this Rochester hotel offers spacious rooms with sofa beds and refrigerators. Start your day with free breakfast before a swim in the indoor pool. The 24-hour fitness center and helpful staff ensure comfort during medical visits.
"Clean room, breakfast selection"
United States
Sonya
The price is ￥14,802
￥17,042 total
includes taxes & fees
Dec 21 - Dec 22
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
Lobby
Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG
3.0 star property
Kutzky Park
9.4 out of 10, Exceptional, (419)
Just a short walk to Mayo Clinic Hospital, this Rochester hotel offers an indoor pool and hot tub. Even Kitchen & Bar serves daily meals, while the 24-hour fitness center keeps routines on track. Kutzky Park Tennis Center is nearby.
"Breakfast is great, staff is chill, place is clean, comfortable. "
United States
Sarah
The price is ￥16,415
￥19,210 total
includes taxes & fees
Dec 13 - Dec 14
Staybridge Suites Rochester - Mayo Clinic Area by IHG
Coffee service
Aspen Select

Aspen Select

Aspen Select
3.5 star property
Rochester
8.4 out of 10, Very Good, (1001)
Five minutes from Mayo Clinic, this hotel offers free WiFi, parking, and continental breakfast served daily. A fitness center keeps your routine on track while the walkable location puts you near Kutzky Park Tennis Center and Cascade Lake Beach.
"Beds are very comfortable!"
United States
Laurie
Aspen Select
View from property
Kahler Grand Hotel

Kahler Grand Hotel

Kahler Grand Hotel
3.0 star property
Downtown Rochester
8.4 out of 10, Very Good, (1821)
Conveniently located just 5 minutes from Mayo Clinic, this historic hotel offers 2 restaurants including Lord Essex Tavern & Grill. Guests appreciate the helpful staff, clean accommodations, and peaceful atmosphere, plus easy access to Plummer Building.
"Staff was friendly and helpful! Will continue to stay here while at the Mayo, "
United States
Gayle
The price is ￥20,851
￥24,005 total
includes taxes & fees
Dec 17 - Dec 18
Kahler Grand Hotel
Exterior
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
3.0 star property
Kutzky Park
9.2 out of 10, Wonderful, (767)
"Clean room and housekeeping service was excellent"
United States
Dawn
The price is ￥13,061
￥15,037 total
includes taxes & fees
Dec 21 - Dec 22
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Pub
TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area
3.0 star property
Downtown Rochester
9.6 out of 10, Exceptional, (480)
This hotel offers easy access to Mayo Clinic within a 15-minute walk, plus a convenient free area shuttle. Guests appreciate the helpful staff, complimentary breakfast, and 24-hour fitness center. Unwind at the bar after visiting nearby Plummer Building.
"Overall great place"
United States
Jill
The price is ￥18,348
￥21,123 total
includes taxes & fees
Dec 26 - Dec 27
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Terrace/patio
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area
3.0 star property
Downtown Rochester
9.2 out of 10, Wonderful, (1002)
Enjoy your stay with an indoor pool, hot tub, and fitness center at this convenient Rochester hotel. A complimentary shuttle, full breakfast, and in-room kitchenettes enhance your visit. The friendly staff provides exceptional service near Shops University Square.
"Clean rooms, very friendly staff and was perfect for our stay, was a 5 to 10 minute walk to Mayo clinic. Great location."
United States
Kim
The price is ￥20,058
￥23,092 total
includes taxes & fees
Dec 21 - Dec 22
Hyatt House Rochester/Mayo Clinic Area
Lobby sitting area
Brentwood Inn & Suites

Brentwood Inn & Suites

Brentwood Inn & Suites
2.5 star property
Downtown Rochester
8.8 out of 10, Excellent, (1003)
Convenient for medical visits, this hotel is just a 5-minute drive from Mayo Clinic and Saint Marys Campus. Guests love the comfortable beds, helpful staff, and daily continental breakfast served from 6-9 AM. Plummer Building and Shops University Square are located nearby.
"Room was clean breakfast was good everybody was helpful "
United States
james
The price is ￥17,493
￥20,138 total
includes taxes & fees
Dec 16 - Dec 17
Brentwood Inn & Suites
View from property
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
2.5 star property
Kutzky Park
9.6 out of 10, Exceptional, (676)
Ideally positioned just 5 minutes from Mayo Clinic with a free area shuttle, this Rochester hotel offers an indoor pool and fitness center. Rooms include refrigerators and microwaves, while free breakfast and parking enhance the value.
"Good place to stay when traveling to Mayo apots"
United States
Carolyn
The price is ￥13,839
￥15,930 total
includes taxes & fees
Dec 22 - Dec 23
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
Courtyard
EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG
4.0 star property
Kutzky Park
9.4 out of 10, Exceptional, (956)
Focused on well-being, this Rochester hotel is a 15-minute walk from Mayo Clinic campuses. Refresh in the indoor pool and hot tub, energize at the 24-hour fitness center, or relax at the bar after exploring nearby Plummer Building.
"Rooms are comfortable and staff was was so professional and helpful."
United States
William
The price is ￥15,753
￥18,446 total
includes taxes & fees
Dec 13 - Dec 14
EVEN Hotel Rochester - Mayo Clinic Area by IHG
Indoor pool, open 9:00 AM to 10:00 PM, pool umbrellas, sun loungers
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 star property
Rochester
8.2 out of 10, Very Good, (785)
Situated just minutes from Mayo Clinic, this Rochester hotel offers an indoor pool and hot tub for relaxation after appointments. Enjoy free breakfast, WiFi, and parking, plus American dining at Wildwood Sports Bar. Nearby shops and restaurants enhance the stay.
"Great place to stay. Freindly staff"
United States
joel
The price is ￥13,887
￥15,987 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Indoor pool, open 5:00 AM to 10:00 PM, sun loungers
Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area
3.5 star property
Downtown Rochester
9.6 out of 10, Exceptional, (543)
Conveniently located near Mayo Clinic, this hotel offers 2 restaurants including rooftop dining, plus a rejuvenating spa and indoor pool. Guest rooms feature refrigerators and microwaves for added comfort during medical visits.
"Very courteous staff, loved the valet guy!"
United States
Jean
The price is ￥26,648
￥30,679 total
includes taxes & fees
Dec 24 - Dec 25
Hilton Rochester Mayo Clinic Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Wykoff attractions

Ed's Museum

You can spend time exploring the galleries in Ed's Museum during your travels in Wykoff. Discover the countryside while you're in the area.
See properties

Top Wykoff Hotel Reviews

Aspen Suites

Aspen Suites

10/10 Excellent
"Everything was impeccable. The staff incredible. Amenities incredible. Colton at the desk was extremely professional and courteous to all of the guests. So impressive and he knew all of the guests by there names and remembered what their needs were. Colton is an employee anyone would want at the helm. Also he was so professional serving soup to guests. This hotel hit all of the marks that anyone would look for during their travel. Thank you all so much. Amazing. Chef JSW"
John 2-night trip
Posted 2 days ago
Aspen Suites

More cheap stays in Wykoff

Super 8 by Wyndham Rochester Mayo Clinic Area

Super 8 by Wyndham Rochester Mayo Clinic Area

106 SE 21st Street Rochester MN
The price is ￥7,930 per night from Dec 20 to Dec 21
￥7,930
￥9,129 total
Dec 20 - Dec 21
includes taxes & fees
7.6/10 Good! (1,004 reviews)

Frequently asked questions

Where is the best place to stay in Wykoff?
Located 24 mi (38.6 km) from the heart of Wykoff, Kahler Grand Hotel is a top choice for your stay based on our traveler data. Other good choices for your stay in the area are Kahler Inn and Suites - Mayo Clinic Area and Hampton Inn Rochester-South. See all available top hotels, or vacation rentals in Wykoff.
What's the top vacation rental that Wykoff has to offer?
SUNNY 3BD, 2BA…ONLY BLOCKS FROM MAYO: Visitors like this Wykoff vacation home rental. It offers a patio, a garden, and air-conditioning to help you feel perfectly comfortable in your new surroundings. See all vacation rentals in Wykoff.
If I need to cancel my hotel reservation in Wykoff, will I receive a refund?
Yes, most hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Wykoff.
Where can I learn more about changing or cancelling my trip to Wykoff?
For more details about changing or cancelling your trip to Wykoff, click here.
What's the best hotel to stay with easy access to Ed's Museum?
Quiet, comfortable bed & breakfast in a gorgeous rural setting! is one of the top choices for your stay based on our traveler data, and this B&B offers free breakfast and private decks. You'll find it 5.5 mi (8.9 km) from Ed's Museum. Other good options around the area include Americas Best Value Inn & Suites Spring Valley and Oakenwald Terrace.
What is the best accommodation for staying close to Rochester International Airport (RST)?
AmericInn by Wyndham Rochester Airport is a popular hotel, featuring free breakfast and an indoor pool. It's located a short 0.6 mi (1 km) from Rochester Intl. Airport. Other choices near the airport include La Quinta Inn & Suites by Wyndham Rochester and Comfort Suites.
How is it staying in Wykoff?
Visitors can enjoy all that Wykoff has to offer including its museums. There are 319 hotels and other accommodations in the surrounding area. Find out more about Wykoff.
What are the top places to visit in Wykoff?
A favorite place to visit is Ed's Museum. You'll also find Forestville Mystery Cave State Park and Four Daughters Vineyard & Winery in the area. Check out what more to see and do in Expedia's Wykoff guide.
What's the weather like in Wykoff?
The hottest months are usually July and August with an average temp of 68°F, while the coldest months are January and February with an average of 22°F. The snowiest months in Wykoff are January, March, February, and April, with each month seeing an average of 8 inches of snowfall.

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