Find Luxury Hotels in St. Charles, MO

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Check availability on St. Charles Luxury Hotels

Our top choices for St. Charles luxury hotels

Seasonal outdoor pool
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.4 out of 10, Very Good, (1005)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
United States
Robyn
The price is ￥23,585
￥30,135 total
includes taxes & fees
Dec 21 - Dec 22
Ameristar Casino Resort and Spa
Exterior
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
St. Charles Historic District
9.4 out of 10, Exceptional, (1007)
"The staff were awesome "
United States
Corey
The price is ￥17,299
￥19,881 total
includes taxes & fees
Dec 28 - Dec 29
Country Inn & Suites by Radisson, St. Charles Historic District
Cleanliness standards
Relax Inn Saint Charles

Relax Inn Saint Charles

Relax Inn Saint Charles
2.0 star property
St. Charles
6.6 out of 10, (1000)
"Great place to stay "
United States
Askar
The price is ￥9,473
￥10,886 total
includes taxes & fees
Dec 17 - Dec 18
Relax Inn Saint Charles
Lobby
Baymont by Wyndham St. Charles

Baymont by Wyndham St. Charles

Baymont by Wyndham St. Charles
2.5 star property
St. Charles
8.0 out of 10, Very Good, (1000)
"Friendly staff, great breakfast and clean"
United States
Darin
Baymont by Wyndham St. Charles
Lobby
Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles
3.5 star property
St. Charles
8.8 out of 10, Excellent, (1018)
"I Loved it I would definitely stay there again"
United States
Roberta
The price is ￥18,477
￥21,235 total
includes taxes & fees
Dec 28 - Dec 29
Embassy Suites by Hilton St. Louis St. Charles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St. Charles Hotel Reviews

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

10/10 Excellent
"I like the hotel."
Qingshu 1-night trip
Posted 23 hours ago
Pear Tree Inn St. Louis Airport

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Frequently asked questions

Are you looking for a luxury hotel for your stay in St. Charles?
During your visit, you might want to enjoy the casinos and shopping which St. Charles is known for.
What's the best luxury hotel in St. Charles?
Ameristar Casino Resort and Spa is a luxury hotel with 6 restaurants and 2 bars, and it's a popular choice for Expedia travelers looking for an elegant place to stay.
When can I expect good weather in St. Charles?
Planning for the weather is an important factor for making your trip to St. Charles a success, especially when you're splurging. The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 37°F. Average annual precipitation for St. Charles is 46 inches.
What's there to see and do in St. Charles?
When you're in St. Charles, enjoy exploring the sights and attractions here including Historic Main Street, First Missouri State Capitol Historic Site, and Katy Trail. If you have a little extra time during your trip, you might want to make a stop at Lewis & Clark Boathouse and Nature Center and St Charles Convention Center.