Find hotels in South Main, Memphis from ￥10,325

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 1 - Dec 2
Tomorrow
Dec 2 - Dec 3
This weekend
Dec 5 - Dec 7
Next weekend
Dec 12 - Dec 14

Filter by

Guest rating
Guest rating
Star rating

Discover 1,626 South Main hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Exterior
The Central Station Memphis, Curio Collection by Hilton

The Central Station Memphis, Curio Collection by Hilton

4.0 star property
South Main
9.0 out of 10, Wonderful, (1004)
"Awesome staff friendly and helpful and awesome location. "
United States
Timothy
The price is ￥17,453
￥21,036 total
includes taxes & fees
Dec 18 - Dec 19
The Central Station Memphis, Curio Collection by Hilton
Egyptian cotton sheets, premium bedding, pillowtop beds, minibar
ARRIVE Memphis

ARRIVE Memphis

4.0 star property
South Main
9.6 out of 10, Exceptional, (1016)
"Great stay "
United States
LaKera
The price is ￥28,112
￥33,695 total
includes taxes & fees
Dec 3 - Dec 4
ARRIVE Memphis
Luxury Penthouse, 6 Bedrooms | Individually decorated, individually furnished, laptop workspace
The Rambler

The Rambler

4.0 star property
South Main
9.2 out of 10, Wonderful, (520)
"The property is wonderful for travel with family. It is a complete apartment, clean beautiful with a good price. I love it "
United States
Rosa
The price is ￥18,748
￥22,576 total
includes taxes & fees
Dec 3 - Dec 4
The Rambler
Grand Suite | Premium bedding, minibar, blackout drapes, iron/ironing board
Hotel Pontotoc

Hotel Pontotoc

2.0 star property
South Main
10.0 out of 10, Exceptional, (2)
"Beautiful hotel, great bar, spacious rooms. Excellent!!!"
United States
Cheryl
The price is ￥40,232
￥47,776 total
includes taxes & fees
Dec 7 - Dec 8
Hotel Pontotoc
Exterior
Big Cypress Lodge

Big Cypress Lodge

5.0 star property
Pinch District, 2.3 km from South Main
9.0 out of 10, Wonderful, (1706)
"Great place to stay!!"
United States
Windy
The price is ￥32,642
￥42,200 total
includes taxes & fees
Dec 2 - Dec 3
Big Cypress Lodge
Lunch and dinner served, American cuisine
Hyatt Place Memphis/Wolfchase Galleria

Hyatt Place Memphis/Wolfchase Galleria

3.0 star property
Wolfchase, 24.7 km from South Main
9.0 out of 10, Wonderful, (1365)
" We really enjoyed our stay."
United States
Jassmin
The price is ￥13,807
￥16,708 total
includes taxes & fees
Dec 21 - Dec 22
Hyatt Place Memphis/Wolfchase Galleria
Seasonal outdoor pool
Comfort Inn Memphis Downtown

Comfort Inn Memphis Downtown

2.5 star property
Downtown Memphis, 1.6 km from South Main
8.8 out of 10, Excellent, (1026)
"Great hotel "
United States
Andre
The price is ￥14,556
￥17,597 total
includes taxes & fees
Dec 7 - Dec 8
Comfort Inn Memphis Downtown
Exterior
avid hotel Memphis - Southaven by IHG

avid hotel Memphis - Southaven by IHG

2.5 star property
20.5 km from South Main
9.0 out of 10, Wonderful, (1010)
"Great place to stay"
United States
Elizabeth
The price is ￥14,868
￥16,355 total
includes taxes & fees
Dec 14 - Dec 15
avid hotel Memphis - Southaven by IHG
Free buffet breakfast
Holiday Inn Express Hotel & Suites Memphis Southwind by IHG

Holiday Inn Express Hotel & Suites Memphis Southwind by IHG

3.0 star property
Southwind, 26.1 km from South Main
8.4 out of 10, Very Good, (1021)
"Our stay was great the room was clean and nicer than expected breakfast was good we enjoyed our stay"
United States
Willie
The price is ￥13,900
￥15,881 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Holiday Inn Express Hotel & Suites Memphis Southwind by IHG
Exterior
Candlewood Suites Memphis East by IHG

Candlewood Suites Memphis East by IHG

2.5 star property
20.8 km from South Main
7.6 out of 10, Good, (372)
"Great place to stay. "
United States
Karista
The price is ￥12,369
￥14,131 total
includes taxes & fees
Dec 14 - Dec 15
Candlewood Suites Memphis East by IHG
Food and drink
Hu. Hotel

Hu. Hotel

3.5 star property
Downtown Memphis, 1.3 km from South Main
8.4 out of 10, Very Good, (1600)
"Great stay!"
United States
Roderick
The price is ￥11,987
￥14,904 total
includes taxes & fees
Dec 7 - Dec 8
Hu. Hotel
Reception
La Quinta Inn & Suites by Wyndham Memphis Airport Graceland

La Quinta Inn & Suites by Wyndham Memphis Airport Graceland

3.0 star property
8.8 km from South Main
7.4 out of 10, Good, (2193)
"Best place to stay"
United States
Mazhar
The price is ￥9,293
￥11,350 total
includes taxes & fees
Dec 4 - Dec 5
La Quinta Inn & Suites by Wyndham Memphis Airport Graceland
Courtyard view
The Guest House at Graceland

The Guest House at Graceland

4.0 star property
Whitehaven, 10 km from South Main
9.4 out of 10, Exceptional, (2872)
"Great hotel"
United States
Ieda
The price is ￥34,064
￥43,619 total
includes taxes & fees
Dec 3 - Dec 4
The Guest House at Graceland
Property amenity
Days Inn by Wyndham Southaven MS

Days Inn by Wyndham Southaven MS

2.0 star property
17.1 km from South Main
7.6 out of 10, Good, (907)
"All good, great location near all services. Great place, well maintained "
Canada
Francois
The price is ￥10,933
￥12,026 total
includes taxes & fees
Dec 2 - Dec 3
Days Inn by Wyndham Southaven MS
Desk, iron/ironing board, free WiFi, bed sheets
Studio 6 Memphis, TN – East Memphis

Studio 6 Memphis, TN – East Memphis

2.0 star property
20.8 km from South Main
7.0 out of 10, Good, (874)
"Good stay "
United States
Cherine
The price is ￥8,432
￥10,325 total
includes taxes & fees
Dec 15 - Dec 16
Studio 6 Memphis, TN – East Memphis
Exterior
La Quinta Inn & Suites by Wyndham Memphis I-240

La Quinta Inn & Suites by Wyndham Memphis I-240

3.0 star property
15.5 km from South Main
8.8 out of 10, Excellent, (471)
"Clean room, staff were polite and helpful and the breakfast was fresh and really good. "
Canada
Sashikala
The price is ￥13,213
￥16,003 total
includes taxes & fees
Dec 14 - Dec 15
La Quinta Inn & Suites by Wyndham Memphis I-240
Terrace/patio
Hyatt Centric Beale Street Memphis

Hyatt Centric Beale Street Memphis

4.0 star property
Downtown Memphis, 0.7 km from South Main
8.8 out of 10, Excellent, (1395)
"Amazing hotel and staff and very convenient location to restaurants and shopping. "
United States
Timothy
The price is ￥22,350
￥26,852 total
includes taxes & fees
Dec 7 - Dec 8
Hyatt Centric Beale Street Memphis
Hypo-allergenic bedding, pillowtop beds, minibar, in-room safe
The Westin Memphis Beale Street

The Westin Memphis Beale Street

4.0 star property
Downtown Memphis, 0.7 km from South Main
8.8 out of 10, Excellent, (1010)
"Very clean and perfect location"
United States
Destiny
The price is ￥21,108
￥25,377 total
includes taxes & fees
Dec 21 - Dec 22
The Westin Memphis Beale Street
Exterior
Courtyard by Marriott Memphis Airport

Courtyard by Marriott Memphis Airport

3.0 star property
8.6 km from South Main
8.2 out of 10, Very Good, (1004)
"The staff that checked me in was amazing "
United States
Cynthia
The price is ￥16,461
￥19,858 total
includes taxes & fees
Dec 7 - Dec 8
Courtyard by Marriott Memphis Airport
Exterior
Hilton Garden Inn Memphis/Southaven, MS

Hilton Garden Inn Memphis/Southaven, MS

3.0 star property
20.4 km from South Main
8.6 out of 10, Excellent, (1010)
"Parking , shopping and food near"
United States
Whitney
The price is ￥14,311
￥15,743 total
includes taxes & fees
Dec 13 - Dec 14
Hilton Garden Inn Memphis/Southaven, MS
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in South Main

Find the best South Main areas and neighborhoods for the activities you enjoy most.
Beale Street showing nightlife, night scenes and street scenes

Downtown Memphis

Home to the Memphis Redbirds and Grizzlies NBA team, this central business district offers entertainment, dining, and attractions like Beale Street, FedExForum, and AutoZone Park. Easily accessible via major highways and public transit options.

Pink Palace Museum featuring a house

East Memphis

East Memphis is beloved for its popular shops. Take some time to explore sights in the area like Theatre Memphis and Memphis Botanic Garden.

Memphis Zoo which includes street scenes

Midtown

Immerse yourself in the arts scene with institutions like Playhouse on the Square and Brooks Museum of Art, or explore Overton Park's Memphis Zoo. Enjoy live music at Cooper-Young's vibrant bars and restaurants, and easily navigate via bike lanes and trolley lines.

Graceland showing a house and a pool

Whitehaven

Graceland mansion, a major tourist attraction, and the renovated David Carnes Park await visitors in this South Memphis neighborhood. Do some shopping at Southland Mall or explore along Elvis Presley Boulevard.

North Memphis

Visitors to North Memphis like its bars and churches, and Burkle Estate is a sight worth a stop.

Top South Main Hotel Reviews

The Westin Memphis Beale Street

The Westin Memphis Beale Street

10/10 Excellent
"Room and location was very nice. "
DEREX 4-night trip
Posted 16 hours ago
The Westin Memphis Beale Street

Explore a world of travel with Expedia

Frequently asked questions

What is South Main like?
You'll be sure to have fun visiting Memphis's South Main neighborhood. Be sure to check out Blues Hall of Fame Museum and Railroad & Trolley Museum as part of your South Main travel plans.
What's a favorite place to stay in South Main?
Based on Expedia customer reviews, ARRIVE Memphis is the highest ranked property in South Main. This hotel is a short 11-minute walk from Beale Street, and it offers a restaurant and a fitness center. Another top choice in the area is The Central Station Memphis, Curio Collection by Hilton.
How many hotels are there in the South Main area?
Expedia has 65 hotels and other accommodations in South Main to choose from, making this an ideal home base for exploring the greater Memphis area.
If I need to cancel my hotel reservation in South Main, will I receive a refund?
Yes! The majority of hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of booking. Put your dates in and click on "Search", then filter by "fully refundable" to get the best deals in South Main.
Where can I learn more about changing or cancelling my trip to South Main?
For additional details about updating your trip to South Main or cancelling it, go to https://www.expedia.com/service/.
What are the top things to see and do in South Main?
Create some family memories with a visit to Blues Hall of Fame Museum or Railroad & Trolley Museum while you're in South Main. When you're sightseeing in Memphis, National Civil Rights Museum and Lorraine Motel are also worth a stop.
How can I get around South Main and the greater Memphis area?
To venture out of town, take a train from Memphis Central Station.