Find hotels in Santee, SC from ¥9,779

Start date: Check-in selected.
To Date
End date: Check-out

    Change your mind

    Book hotels with free cancellation

    Treat yourself

    Sign in to save 10% or more on thousands of hotels

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Compare 290 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Tru By Hilton Santee
2.5 star property
9.2 out of 10, Wonderful, (575)
"Great stay"
United States
Shannon
The price is ¥14,954
¥16,597 total
includes taxes & fees
Nov 2 - Nov 3
Tru By Hilton Santee
Comfort Inn & Suites Santee
2.5 star property
8.0 out of 10, Very Good, (1000)
"Service was great breakfast was good"
United States
Gary
The price is ¥15,434
¥17,132 total
includes taxes & fees
Nov 2 - Nov 3
Comfort Inn & Suites Santee
Baymont by Wyndham Santee
2.5 star property
8.0 out of 10, Very Good, (1374)
"Good overall stay."
United States
Junming
The price is ¥11,392
¥12,644 total
includes taxes & fees
Oct 26 - Oct 27
Baymont by Wyndham Santee
Fairfield Inn & Suites by Marriott Santee
2.5 star property
9.8 out of 10, Exceptional, (1003)
"Great stay for a quick weekend getaway!"
United States
Danielle
The price is ¥19,074
¥21,173 total
includes taxes & fees
Nov 11 - Nov 12
Fairfield Inn & Suites by Marriott Santee
Hampton Inn Santee-I-95
2.5 star property
9.6 out of 10, Exceptional, (1001)
"Rooms were nice size and very clean. Staff was so nice and helped us find some local spots to eat. Highly recommend "
United States
Lisa
The price is ¥18,675
¥20,730 total
includes taxes & fees
Nov 2 - Nov 3
Hampton Inn Santee-I-95
Holiday Inn Santee by IHG
3.0 star property
8.2 out of 10, Very Good, (956)
"Great hotel w"
United States
Elizabeth
The price is ¥18,006
¥19,986 total
includes taxes & fees
Nov 23 - Nov 24
Holiday Inn Santee by IHG
Travelodge by Wyndham Santee
2.0 star property
7.0 out of 10, Good, (663)
"Good location "
United States
Jessica
The price is ¥8,811
¥9,779 total
includes taxes & fees
Nov 5 - Nov 6
Travelodge by Wyndham Santee
Quality Inn & Suites
2.5 star property
6.0 out of 10, (443)
"Great place. Excellent people. Great service"
United States
Jesse
The price is ¥8,264
¥10,015 total
includes taxes & fees
Oct 30 - Oct 31
Quality Inn & Suites
Best Western Plus Santee Inn
2.5 star property
8.8 out of 10, Excellent, (1000)
"We really enjoyed our stay and will be back!"
United States
Mary
The price is ¥20,660
¥22,933 total
includes taxes & fees
Nov 3 - Nov 4
Best Western Plus Santee Inn
Ramada by Wyndham Santee I-95
2.0 star property
6.2 out of 10, (537)
"The grounds and property were clean and you could tell they take pride in what they're offering."
United States
Eric
The price is ¥10,510
¥11,667 total
includes taxes & fees
Nov 3 - Nov 4
Ramada by Wyndham Santee I-95
Red Roof Inn Santee
2.0 star property
6.6 out of 10, (630)
"Despite offering breakfast, it was lackluster "
United States
Seth
The price is ¥9,569
¥10,623 total
includes taxes & fees
Nov 3 - Nov 4
Red Roof Inn Santee
Super 8 by Wyndham Santee
2.0 star property
6.8 out of 10, (435)
"The nicest bathroom on our 12 day trip"
United States
Rhonda
The price is ¥11,393
¥12,646 total
includes taxes & fees
Nov 5 - Nov 6
Super 8 by Wyndham Santee
Econo Lodge
2.0 star property
6.4 out of 10, (309)
"Check in was easy."
United States
Amy
The price is ¥9,613
¥10,671 total
includes taxes & fees
Nov 6 - Nov 7
Econo Lodge
Tru by Hilton Orangeburg
2.5 star property
9.2 out of 10, Wonderful, (1002)
"Great little hotel. Perfect for a short stay. "
United States
Mark
The price is ¥16,069
¥17,837 total
includes taxes & fees
Nov 11 - Nov 12
Tru by Hilton Orangeburg
Spark by Hilton Orangeburg
2.5 star property
7.8 out of 10, Good, (1001)
"Clean, quiet, nice place for an overnight stay"
United States
Joseph
The price is ¥13,247
¥14,704 total
includes taxes & fees
Nov 2 - Nov 3
Spark by Hilton Orangeburg
Comfort Inn & Suites Orangeburg
2.5 star property
8.0 out of 10, Very Good, (523)
"EVERYTHING WAS CLEAN AND NICE"
United States
Debra
The price is ¥14,849
¥16,484 total
includes taxes & fees
Nov 2 - Nov 3
Comfort Inn & Suites Orangeburg
Days Inn by Wyndham St George
2.5 star property
7.6 out of 10, Good, (1003)
"The host was very helpful. The rooms are nice and the beds are very comfortable."
United States
Lloyd
The price is ¥10,201
¥11,323 total
includes taxes & fees
Nov 9 - Nov 10
Days Inn by Wyndham St George
Hampton Inn Manning
2.5 star property
8.4 out of 10, Very Good, (985)
"Clean, great staff, and comfortable beds. "
United States
Micah
The price is ¥18,196
¥20,198 total
includes taxes & fees
Nov 4 - Nov 5
Hampton Inn Manning
SureStay Hotel by Best Western Manning
2.5 star property
8.6 out of 10, Excellent, (1005)
"My favorite place to stay when in Manning, SC Newly renovated- from floor to ceiling Great front desk staff- 5 Star plus"
United States
Rebecca
The price is ¥15,106
¥16,768 total
includes taxes & fees
Nov 23 - Nov 24
SureStay Hotel by Best Western Manning
Fairfield Inn by Marriott Orangeburg
2.5 star property
8.4 out of 10, Very Good, (663)
"Enjoyed my stay for homecoming go Bulldogs ! "
United States
David
The price is ¥12,760
¥14,164 total
includes taxes & fees
Nov 2 - Nov 3
Fairfield Inn by Marriott Orangeburg
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Santee attractions

Learn more about Santee

Nestled along Lake Marion, this charming town offers prime fishing and boating opportunities for outdoor enthusiasts. Visitors can tee off at Santee National Golf Club or explore nearby Santee State Park's hiking trails and campgrounds.

Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina

Top Santee Hotel Reviews

More cheap stays in Santee

Frequently asked questions

Where is the best place for a stay in Santee?
Hampton Inn Santee-I-95 is a favorite property for Expedia customers. This hotel offers free breakfast and free parking. Other top choices based on traveler reviews include Fairfield Inn & Suites by Marriott Santee and Tru By Hilton Santee. See all available top hotels, or vacation rentals in Santee.
What are some of the best vacation rentals in Santee?
Wyndham Vacation Resorts Lake Marion: Visitors give good reviews to this Santee vacation home rental, which is equipped with an outdoor pool, free WiFi, and cable TV to help you feel comfortable during your stay. It has 3 bedrooms as well as a kitchen with a full-sized fridge, a dishwasher, and a stovetop, so you can cook with friends or family. Our travelers also rate Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95! as a favorite home for rent in Santee. See all vacation rentals in Santee.
If I need to cancel my hotel reservation in Santee, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santee.
Where can I learn more about changing or cancelling my trip to Santee?
For more information about updating your trip to Santee or cancelling it, click here.
What's the best budget-friendly hotel in Santee?
Based on reviews, Baymont by Wyndham Santee is a popular hotel for our travelers who want a more economical choice, and features free breakfast and free WiFi. View all budget hotels in Santee.
What's the best hotel for a family vacation in Santee?
Fairfield Inn & Suites by Marriott Santee is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Comfort Inn & Suites Santee is another choice for your family trip. Find more child-friendly accommodations in Santee.
What is the top LGBTQ-friendly accommodation in Santee?
Fairfield Inn & Suites by Marriott Santee is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Hampton Inn Santee-I-95 and Holiday Inn Santee by IHG are other good options for your stay. See all available hotels listed as LGBTQ-friendly in Santee.
What's the best pet-friendly accommodation in Santee?
Baymont by Wyndham Santee is a top hotel for people traveling with their pets, and offers concierge services and free WiFi for its human guests. Other good choices for you and your pet's trip include Tru By Hilton Santee and Fairfield Inn & Suites by Marriott Santee. See more pet-friendly hotel accommodations in Santee.
Where is the best place to stay near Santee State Park?
Baymont by Wyndham Santee is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free parking. It's located 3 mi (4.8 km) from Santee State Park. Other good choices within 5 miles include Best Western Plus Santee Inn and Holiday Inn Santee, an IHG Hotel.
What about the best place to stay close to Santee Outlets?
One of the top choices for your stay is Baymont by Wyndham Santee, located a short 0.4 mi (0.6 km) from Santee Outlets, and this hotel offers free breakfast and free parking. Best Western Plus Santee Inn and Fairfield Inn & Suites by Marriott Santee are two other good choices in the immediate area.
What's the best golf hotel in Santee?
Holiday Inn Santee by IHG is a top hotel that has an adjacent golf course and features free WiFi. Other good options to stay near a golf course include Ramada by Wyndham Santee I-95 and Super 8 by Wyndham Santee. Visit Santee Cooper Country Club or Santee National Golf Club to perfect your golf swing. See more golf hotels in Santee.
What are some accommodations with pools in Santee?
Fairfield Inn & Suites by Marriott Santee is a top hotel with a pool, free buffet breakfast, and free WiFi. Quality Inn & Suites is another choice with an onsite pool. View all hotels with pools in Santee.
What's the best place to stay near Columbia Metropolitan Airport (CAE)?
Country Inn & Suites by Radisson, Columbia Airport, SC is a popular hotel, featuring free breakfast and an indoor pool. It's located a short 1.7 mi (2.8 km) from Columbia Metropolitan Airport. Other places to stay close to the airport are Sleep Inn Airport and Red Roof Inn Columbia, SC Airport.
What is staying in Santee like?
Families will find kid-friendly activities in Santee, and visitors give high marks for the top-notch restaurants. This welcoming city also attracts tourists with its golf courses and coffeehouses. In Santee, there are 127 hotels and other accommodations to choose from. Find out more about Santee.
What is there to see in Santee?
Favorite places to visit include Santee Cooper Country Club, Santee National Golf Club, and Santee State Park. A couple of additional sights to add to your agenda are Lake Marion and Santee Town Hall. Check out what more to see and do in Expedia's Santee guide.
What's the seasonal weather like in Santee?
The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 52°F. Average annual precipitation for Santee is 55 inches.

Explore a world of travel with Expedia