Find hotels in Santee, SC from ¥9,556

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Our top choices for Santee hotels

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
2.5 star property
Santee
9.8 out of 10, Exceptional, (1005)
Set in a peaceful location, this hotel offers free breakfast, WiFi, and parking. Guests can enjoy the outdoor pool or workout at the health club. The helpful staff ensure comfort while Santee Cooper Country Club and Santee National Golf Club are just moments away.

"Spotless clean room The staff was so courteous and friendly "
United States
Amani
The price is ¥18,853
¥20,928 total
includes taxes & fees
Dec 23 - Dec 24
Fairfield Inn & Suites by Marriott Santee

Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (637)
Energizing Santee hotel with an indoor pool for morning swims and a 24-hour fitness center. Enjoy free breakfast, WiFi, and parking. Close to Santee Cooper Country Club and Santee National Golf Club. Guests rave about the helpful staff.

"Nice place to stay"
Canada
Tanya
The price is ¥15,082
¥16,741 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Tru By Hilton Santee

Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
2.5 star property
Santee
9.6 out of 10, Exceptional, (1002)
"Rooms are clean, friendly staff and easy to get off and back on the highway. "
United States
Michelle
The price is ¥17,450
¥19,371 total
includes taxes & fees
Dec 23 - Dec 24
Hampton Inn Santee-I-95

Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1415)
This peaceful hotel offers complimentary breakfast, WiFi and parking near Santee National Golf Club. Guests consistently praise the quiet atmosphere, comfortable accommodations and helpful staff. The convenient location provides easy access to everything needed.

"Very friendly staff. "
United States
Ramil
The price is ¥12,463
¥13,834 total
includes taxes & fees
Dec 16 - Dec 17
Baymont by Wyndham Santee

Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1001)
"Nice rooms and very good breakfast items."
United States
Stephen
The price is ¥18,409
¥20,433 total
includes taxes & fees
Dec 22 - Dec 23
Best Western Plus Santee Inn

Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
3.0 star property
Santee
8.2 out of 10, Very Good, (972)
Adjacent to a golf course, this hotel offers an indoor pool and convenient on-site dining. Guests love the helpful staff and clean rooms. Nearby attractions include Santee Cooper Country Club and Santee National Golf Club, while free WiFi and parking enhance your stay.

"Was able to walk to convenience store and other dinning alternatives. Safe secure building"
United States
Joan
The price is ¥16,204
¥17,986 total
includes taxes & fees
Dec 17 - Dec 18
Holiday Inn Santee by IHG

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1002)
Escape to a tranquil retreat in Santee's entertainment district where helpful staff welcome you. Enjoy the seasonal outdoor pool after exploring nearby Santee Cooper Country Club, then recharge with complimentary breakfast before your next adventure.

"Close to the highway with a safe location."
United States
Benjamin
The price is ¥16,025
¥17,787 total
includes taxes & fees
Dec 21 - Dec 22
Comfort Inn & Suites Santee

Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
2.0 star property
Santee
7.0 out of 10, Good, (678)
This Santee hotel offers daily continental breakfast and complimentary WiFi and parking. Praised for helpful staff and clean rooms, the location provides easy access to Santee Cooper Country Club and Santee National Golf Club.

"The room was very nice. It was newly renovated and I loved the upgrade. The beds were comfortable and warm. We didn’t eat breakfast because we were meeting someone for breakfast. "
United States
Alice
The price is ¥9,504
¥10,550 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Travelodge by Wyndham Santee

Red Roof Inn Santee

Red Roof Inn Santee
2.0 star property
Santee
6.6 out of 10, (637)
A perfect stopover with free breakfast, parking, and WiFi at this lakeside hotel. Just minutes from Santee Cooper Country Club and offering easy access to water skiing adventures. Modern rooms provide a restful retreat after exploring Santee National Golf Club.

"It's a good stop for the price "
United States
Martin
The price is ¥10,905
¥12,104 total
includes taxes & fees
Dec 16 - Dec 17
Red Roof Inn Santee

Super 8 by Wyndham Santee

Super 8 by Wyndham Santee
2.0 star property
Santee
6.8 out of 10, (440)
Tranquil accommodations next to Santee Cooper Country Club with a refreshing seasonal outdoor pool. Free perks include daily on-the-go breakfast, WiFi, and parking. Conveniently located near Santee National Golf Club for the perfect golf getaway.

"The staff was very friendly and helpful. Room was clean and beds were so comfortable. "
United States
Kathy
The price is ¥10,907
¥12,106 total
includes taxes & fees
Dec 16 - Dec 17
Super 8 by Wyndham Santee

Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
2.5 star property
Santee
6.0 out of 10, (455)
Immerse yourself in Southern hospitality at this Quality Inn where 7 restaurants and a seasonal outdoor pool await. Enjoy free breakfast, WiFi and parking while exploring nearby Santee Cooper Country Club. Guests consistently praise the helpful staff and clean accommodations.

"exellent service"
United States
Mirjana
The price is ¥8,476
¥10,273 total
includes taxes & fees
Dec 21 - Dec 22
Quality Inn & Suites Santee I-95

Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95
2.0 star property
Santee
6.2 out of 10, (541)
This golf-adjacent hotel offers an outdoor pool with poolside bar, plus a 24-hour fitness center for active travelers. Rooms include refrigerators and microwaves. Santee Cooper Country Club is nearby, with free WiFi and parking for added convenience.

"The grounds and property were clean and you could tell they take pride in what they're offering."
United States
Eric
The price is ¥11,371
¥12,621 total
includes taxes & fees
Jan 10 - Jan 11, 2026
Ramada by Wyndham Santee I-95

Econo Lodge Santee

Econo Lodge Santee
2.0 star property
Santee
6.4 out of 10, (309)
This budget-friendly hotel sits close to Santee Cooper Country Club and Santee National Golf Club. Guests appreciate the convenient amenities including complimentary WiFi, free parking, and 24-hour reception service.

"Check in was easy."
United States
Amy
The price is ¥9,853
¥10,937 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Econo Lodge Santee

Tru by Hilton Orangeburg

Tru by Hilton Orangeburg
2.5 star property
Orangeburg
9.2 out of 10, Wonderful, (1004)
"Staff are great, room is clean and amenities very amusing "
United States
Salah
The price is ¥16,079
¥17,848 total
includes taxes & fees
Dec 21 - Dec 22
Tru by Hilton Orangeburg

Fairfield Inn by Marriott Orangeburg

Fairfield Inn by Marriott Orangeburg
2.5 star property
Orangeburg
8.4 out of 10, Very Good, (695)
Situated near attractions like Smith-Hammond-Middleton Memorial Center, this hotel offers seasonal swimming and convenient workout options. Enjoy complimentary breakfast, WiFi, and parking while business travelers appreciate the friendly staff and clean accommodations.

"The room was absolutely a pleasure to stay in. The bed was incredibly comfortable. The room was well stocked and thoroughly clean. "
United States
Robin
The price is ¥13,088
¥14,528 total
includes taxes & fees
Dec 16 - Dec 17
Fairfield Inn by Marriott Orangeburg

SpringHill Suites by Marriott Orangeburg

SpringHill Suites by Marriott Orangeburg
2.5 star property
Orangeburg
9.0 out of 10, Wonderful, (673)
Dive into this Orangeburg hotel's refreshing indoor pool, then start your day with complimentary continental breakfast. With free WiFi and parking, plus a helpful staff and clean accommodations, you'll be minutes from local attractions and museums.

"The room was perfect and the staff was friendly and welcoming "
United States
Milton
The price is ¥16,316
¥18,112 total
includes taxes & fees
Dec 21 - Dec 22
SpringHill Suites by Marriott Orangeburg

Hampton Inn Manning

Hampton Inn Manning
2.5 star property
Manning
8.4 out of 10, Very Good, (1000)
Located just a short drive from Charleston International Airport, this hotel offers clean accommodations with premium comfort. Relax at the bar after a workout in the 24-hour fitness center. Free breakfast, WiFi, and parking enhance your visit.

"Clean, great staff, and comfortable beds. "
United States
Micah
The price is ¥18,074
¥20,062 total
includes taxes & fees
Dec 22 - Dec 23
Hampton Inn Manning

SureStay Hotel by Best Western Manning

SureStay Hotel by Best Western Manning
2.5 star property
Manning
8.6 out of 10, Excellent, (1003)
This business-friendly hotel offers free WiFi and full breakfast daily. Clean rooms provide a relaxing atmosphere after exploring Manning. Previous guests highly praise the helpful staff and overall cleanliness.

"Easy check in and out. Friendly staff, quiet and cozy. Breakfast is average but plenty to choose from. "
United States
Monica
The price is ¥13,867
¥15,392 total
includes taxes & fees
Dec 21 - Dec 22
SureStay Hotel by Best Western Manning

Holiday Inn Express & Suites Orangeburg by IHG

Holiday Inn Express & Suites Orangeburg by IHG
2.5 star property
Orangeburg
8.6 out of 10, Excellent, (793)
Just off Interstate 26, this Orangeburg hotel offers a seasonal outdoor pool and 24-hour fitness center. Enjoy complimentary WiFi, breakfast, and parking. Clean rooms provide a comfortable base for exploring nearby attractions including the I.P. Stanback Museum & Planetarium.

"The room was spotless and the staff was courteous. "
United States
Terrance
The price is ¥17,762
¥19,716 total
includes taxes & fees
Dec 21 - Dec 22
Holiday Inn Express & Suites Orangeburg by IHG

Red Roof Inn St George, SC

Red Roof Inn St George, SC
2.5 star property
St. George
7.4 out of 10, Good, (633)
This roadside hotel in St. George offers convenient freebies including WiFi, parking, and on-the-go breakfast. Clean rooms provide a comfortable base while exploring nearby Saint George Public Library and Jennie J McMahan Library.

"Room was clean and the staff were good. Overall I would recommend this hotel!"
Canada
George
The price is ¥10,312
¥11,446 total
includes taxes & fees
Dec 21 - Dec 22
Red Roof Inn St George, SC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Santee attractions

Learn more about Santee

Nestled along Lake Marion, this charming town offers prime fishing and boating opportunities for outdoor enthusiasts. Visitors can tee off at Santee National Golf Club or explore nearby Santee State Park's hiking trails and campgrounds.

Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina

Top Santee Hotel Reviews

More cheap stays in Santee

Frequently asked questions

Where is the best place for a stay in Santee?
Hampton Inn Santee-I-95 is a favorite property for Expedia customers. This hotel offers free breakfast and free parking. Other top choices based on traveler reviews include Fairfield Inn & Suites by Marriott Santee and Tru By Hilton Santee. See all available top hotels, or vacation rentals in Santee.
What are some of the best vacation rentals in Santee?
Wyndham Vacation Resorts Lake Marion: Visitors give good reviews to this Santee vacation home rental, which is equipped with an outdoor pool, free WiFi, and cable TV to help you feel comfortable during your stay. Kitchen amenities include a full-sized fridge, a dishwasher, and a stovetop. Our travelers also rate Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95! as a favorite home for rent in Santee. See all vacation rentals in Santee.
If I need to cancel my hotel reservation in Santee, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santee.
Where can I learn more about changing or cancelling my trip to Santee?
For more information about updating your trip to Santee or cancelling it, click here.
What's the best budget-friendly hotel in Santee?
Based on reviews, Baymont by Wyndham Santee is a popular hotel for our travelers who want a more economical choice, and features free breakfast and free WiFi. View all budget hotels in Santee.
What's the best hotel for a family vacation in Santee?
Fairfield Inn & Suites by Marriott Santee is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Comfort Inn & Suites Santee is another choice for your family trip. Find more child-friendly accommodations in Santee.
What is the top LGBTQ-friendly accommodation in Santee?
Fairfield Inn & Suites by Marriott Santee is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Hampton Inn Santee-I-95 and Holiday Inn Santee by IHG are other good options for your stay. See all available hotels listed as LGBTQ-friendly in Santee.
What's the best pet-friendly accommodation in Santee?
Tru By Hilton Santee is a top dog-friendly hotel, and offers an indoor pool along with free WiFi for its human guests. Other good choices for you and your pet's trip include Baymont by Wyndham Santee and Fairfield Inn & Suites by Marriott Santee. See more pet-friendly hotel accommodations in Santee.
Where is the best place to stay near Santee State Park?
Baymont by Wyndham Santee is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free parking. It's located 3 mi (4.8 km) from Santee State Park. Other good choices within 5 miles include Best Western Plus Santee Inn and Holiday Inn Santee, an IHG Hotel.
What about the best place to stay close to Santee Outlets?
One of the top choices for your stay is Baymont by Wyndham Santee, located a short 0.4 mi (0.6 km) from Santee Outlets, and this hotel offers free breakfast and free parking. Best Western Plus Santee Inn and Fairfield Inn & Suites by Marriott Santee are two other good choices in the immediate area.
What's the best golf hotel in Santee?
Holiday Inn Santee by IHG is a top hotel that has an adjacent golf course and features free WiFi. Other good options to stay near a golf course include Ramada by Wyndham Santee I-95 and Waterfront Condo on Lake Marion. Visit Santee Cooper Country Club or Santee National Golf Club to perfect your golf swing. See more golf hotels in Santee.
What are some accommodations with pools in Santee?
Fairfield Inn & Suites by Marriott Santee is a top hotel with a pool, free buffet breakfast, and free WiFi. Quality Inn & Suites Santee I-95 is another choice with an onsite pool. View all hotels with pools in Santee.
What's the best place to stay near Columbia Metropolitan Airport (CAE)?
Country Inn & Suites by Radisson, Columbia Airport, SC is a popular hotel, featuring free breakfast and an indoor pool. It's located a short 1.7 mi (2.8 km) from Columbia Metropolitan Airport. Other places to stay close to the airport are Sleep Inn Airport and Red Roof Inn Columbia, SC Airport.
What is staying in Santee like?
Families will find kid-friendly activities in Santee, and visitors give high marks for the top-notch restaurants. This welcoming city also attracts tourists with its golf courses and coffeehouses. In Santee, there are 127 hotels and other accommodations to choose from. Find out more about Santee.
What is there to see in Santee?
Favorite places to visit include Santee Cooper Country Club, Santee State Park, and Lake Marion. A couple of additional sights to add to your agenda are Santee National Golf Club and Santee Town Hall. Check out what more to see and do in Expedia's Santee guide.
What's the seasonal weather like in Santee?
The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 52°F. Average annual precipitation for Santee is 55 inches.

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