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Nov 6 - Nov 8
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Nov 13 - Nov 15

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Our top choices for Santa Fe hotels

A hotel with a covered entrance, stone facade, and blue lighting accents.

1. Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
3.5 star property
Alachua
9.4 out of 10, Exceptional, (1,003 reviews)
"Great stay!!"
United States
Austin
The price is ļæ„15,598
ļæ„17,548 total
includes taxes & fees
Nov 15 - Nov 16
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
A modern kitchen area with a central counter, various food stations, and a chalkboard menu.

2. Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75
2.5 star property
Alachua
9.4 out of 10, Exceptional, (570 reviews)
"Great breakfast!"
United States
Pamela
The price is ļæ„17,276
ļæ„19,436 total
includes taxes & fees
Nov 8 - Nov 9
Hampton Inn & Suites Alachua I-75
A large, multi-story hotel with a central courtyard, palm trees, and an American flag.

3. Best Western Gateway Grand

Best Western Gateway Grand
3.0 star property
Gainesville
8.6 out of 10, Excellent, (1,517 reviews)
"We enjoyed our stay"
United States
Diane
The price is ļæ„13,323
ļæ„14,989 total
includes taxes & fees
Nov 8 - Nov 9
Best Western Gateway Grand
A modern hotel with a prominent 'La Quinta' sign, a covered entrance, and a well-maintained outdoor area with a parking lot.

4. La Quinta by Wyndham Gainesville

La Quinta by Wyndham Gainesville
3.0 star property
Gainesville
9.2 out of 10, Wonderful, (1,388 reviews)
"Good hotel."
United States
Andy H
The price is ļæ„15,598
ļæ„17,549 total
includes taxes & fees
Nov 2 - Nov 3
La Quinta by Wyndham Gainesville
A cozy restaurant with wooden beams, yellow walls, and a bar area with coffee machines.

5. Quality Inn Alachua - Gainesville Area

Quality Inn Alachua - Gainesville Area
2.5 star property
Alachua
7.2 out of 10, Good, (1,001 reviews)
"The staff was very nice. Bed was comfortable."
United States
Gerald
The price is ļæ„11,382
ļæ„12,805 total
includes taxes & fees
Nov 9 - Nov 10
Quality Inn Alachua - Gainesville Area
A poolside area with a fire pit, lounge chairs, and a glass of wine.

6. Hyatt Place Gainesville Downtown

Hyatt Place Gainesville Downtown
3.0 star property
Downtown Gainesville
9.2 out of 10, Wonderful, (1,241 reviews)
"Excelent Hotel!"
United States
Misak
The price is ļæ„18,119
ļæ„20,384 total
includes taxes & fees
Nov 8 - Nov 9
Hyatt Place Gainesville Downtown
A gym with exercise equipment, wooden flooring, and artwork on the walls.

7. Comfort Suites Gainesville near University

Comfort Suites Gainesville near University
2.5 star property
Gainesville
9.2 out of 10, Wonderful, (1,552 reviews)
"Nice property would stay again"
United States
Samantha
The price is ļæ„12,053
ļæ„14,032 total
includes taxes & fees
Nov 27 - Nov 28
Comfort Suites Gainesville near University
A multi-story hotel with a central entrance, palm trees, and a clear sky.

8. Country Inn & Suites by Radisson, Gainesville, FL

Country Inn & Suites by Radisson, Gainesville, FL
3.0 star property
Gainesville
9.2 out of 10, Wonderful, (2,029 reviews)
"Great place to stay"
United States
sherry
The price is ļæ„13,928
ļæ„15,669 total
includes taxes & fees
Nov 8 - Nov 9
Country Inn & Suites by Radisson, Gainesville, FL
A modern bar area with a long counter, green bar stools, and a television displaying a golf game.

9. Fairfield Inn & Suites by Marriott Gainesville I-75

Fairfield Inn & Suites by Marriott Gainesville I-75
3.0 star property
Gainesville
9.6 out of 10, Exceptional, (1,000 reviews)
"Great proximity to campus and wonderful breakfast!"
United States
Robert
The price is ļæ„18,750
ļæ„21,093 total
includes taxes & fees
Nov 8 - Nov 9
Fairfield Inn & Suites by Marriott Gainesville I-75
A modern hotel room with a large bed, a flat-screen TV, a desk, and a mural of a landscape.

10. Clarion Pointe Alachua - Gainesville Area

Clarion Pointe Alachua - Gainesville Area
2.0 star property
Alachua
8.0 out of 10, Very good, (26 reviews)
"Big beautiful pool, room was very clean, bed was super comfortable, staff was awesome!"
United States
Debra
The price is ļæ„9,480
ļæ„11,454 total
includes taxes & fees
Nov 22 - Nov 23
Clarion Pointe Alachua - Gainesville Area
A modern reception desk area with a blue geometric wall design, wooden accents, and a visible reception counter.

11. Holiday Inn Express Starke by IHG

Holiday Inn Express Starke by IHG
2.5 star property
Starke
9.6 out of 10, Exceptional, (644 reviews)
"Very clean rooms and wonderful staff."
United States
Georgia
The price is ļæ„16,229
ļæ„18,015 total
includes taxes & fees
Nov 29 - Nov 30
Holiday Inn Express Starke by IHG
A hotel room with a bed, bedside tables, a TV, a window with curtains, and a wall with artwork.

12. Sleep Inn & Suites University/Shands

Sleep Inn & Suites University/Shands
2.5 star property
Gainesville
8.8 out of 10, Excellent, (1,324 reviews)
"The hotel is nice, the staff was friendly, great location and the room was very clean"
United States
Rose
The price is ļæ„12,053
ļæ„14,446 total
includes taxes & fees
Dec 2 - Dec 3
Sleep Inn & Suites University/Shands
An outdoor patio with wicker furniture, stone walls, and a barbecue grill.

13. TownePlace Suites by Marriott Gainesville Northwest

TownePlace Suites by Marriott Gainesville Northwest
3.0 star property
Gainesville
8.4 out of 10, Very good, (784 reviews)
"Overall experience was excellent! I would definitely stay again when Iā€™m back in Gainesville,Fl. Go Gators!!!"
United States
Adrian Jose
The price is ļæ„16,500
ļæ„18,563 total
includes taxes & fees
Dec 1 - Dec 2
TownePlace Suites by Marriott Gainesville Northwest
A swimming pool with a metal ladder, surrounded by a white fence and green chairs.

14. Best Western Waldo Inn and Suites

Best Western Waldo Inn and Suites
2.5 star property
Waldo
8.8 out of 10, Excellent, (1,004 reviews)
"Close to downtown St Augustine - about 15 mins away"
United States
Sarah
The price is ļæ„13,257
ļæ„14,914 total
includes taxes & fees
Nov 9 - Nov 10
Best Western Waldo Inn and Suites
A stone water feature with cascading water, surrounded by a brick wall and greenery.

15. BlueGem Motel

BlueGem Motel
2.0 star property
High Springs
9.2 out of 10, Wonderful, (484 reviews)
"Very clean rooms and homey atmosphere!"
United States
Myra
The price is ļæ„13,574
ļæ„15,271 total
includes taxes & fees
Nov 2 - Nov 3
BlueGem Motel
A modern hotel lobby with a curved ceiling, a central seating area with a sofa and ottoman, a bar area, and a dining space with chairs and tables.

16. SpringHill Suites by Marriott Gainesville

SpringHill Suites by Marriott Gainesville
3.0 star property
Gainesville
8.8 out of 10, Excellent, (1,000 reviews)
"Clean room , nice staffs !"
United States
Hoang
The price is ļæ„13,437
ļæ„15,116 total
includes taxes & fees
Nov 15 - Nov 16
SpringHill Suites by Marriott Gainesville
A spacious lobby with a sectional sofa, a wooden cabinet, and a television mounted on the wall.

17. Drury Inn & Suites Gainesville

Drury Inn & Suites Gainesville
3.0 star property
Gainesville
9.6 out of 10, Exceptional, (1,674 reviews)
"Hotel was immaculate-Staff extremely friendly and Meals included were great"
United States
Michael
The price is ļæ„16,542
ļæ„18,610 total
includes taxes & fees
Nov 26 - Nov 27
Drury Inn & Suites Gainesville
Lobby sitting area

18. HOM Hotel Gainesville, SureStay Collection by Best Western

HOM Hotel Gainesville, SureStay Collection by Best Western
2.5 star property
Gainesville
8.6 out of 10, Excellent, (2,163 reviews)
"Great hotel"
Canada
Jenna
The price is ļæ„11,414
ļæ„12,841 total
includes taxes & fees
Nov 8 - Nov 9
HOM Hotel Gainesville, SureStay Collection by Best Western
An outdoor seating area with wicker furniture and a central fire feature.

19. Hotel Indigo Gainesville-Celebration Pointe by IHG

Hotel Indigo Gainesville-Celebration Pointe by IHG
3.5 star property
Gainesville
9.2 out of 10, Wonderful, (1,056 reviews)
"Very clean and nice hotel! Stayed with our 2 kids and felt very safe to stay there"
United States
Dalton
The price is ļæ„15,441
ļæ„17,545 total
includes taxes & fees
Nov 29 - Nov 30
Hotel Indigo Gainesville-Celebration Pointe by IHG
A spacious living area with a curved ceiling, a large flat-screen TV, and a modern sofa.

20. Holiday Inn Gainesville - University Center by IHG

Holiday Inn Gainesville - University Center by IHG
3.0 star property
University Heights
8.2 out of 10, Very good, (1,000 reviews)
"Always a great place to stay when visiting my son at UF"
United States
Tonya
The price is ļæ„14,338
ļæ„16,130 total
includes taxes & fees
Nov 29 - Nov 30
Holiday Inn Gainesville - University Center by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Hotels recommended for families in Santa Fe

A hotel with a covered entrance, stone facade, and blue lighting accents.

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
3.5 star property
Alachua
9.4 out of 10, Exceptional, (1,003)
The price is ļæ„15,598
ļæ„17,548 total
includes taxes & fees
Nov 15 - Nov 16
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
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Top Santa Fe Hotel Reviews

HOM Hotel Gainesville, SureStay Collection by Best Western

HOM Hotel Gainesville, SureStay Collection by Best Western

10/10 Excellent
"This is my 2nd time here. Highly recommended. Very happy with everything."
Farhana 2-night trip
Posted 15 hours ago
HOM Hotel Gainesville, SureStay Collection by Best Western
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

10/10 Excellent
"Everything was awesome! Breakfast was great, rooms were awesome and the staff was top notch!! We will be back"
Joanne 2-night trip
Posted 1 day ago
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

More cheap stays in Santa Fe

Red Roof Inn PLUS+ Gainesville

Red Roof Inn PLUS+ Gainesville

3500 Southwest 42nd St Gainesville FL
The price is ļæ„9,216 per night from Dec 1 to Dec 2
ļæ„9,216
ļæ„10,368 total
Dec 1 - Dec 2
includes taxes & fees

Frequently asked questions

What's the best place for a stay in Santa Fe?
Located 18.6 mi (30 km) from the heart of Santa Fe, Drury Inn & Suites Gainesville is a top choice for your stay based on our traveler data. Other good choices for your visit to the area are Sleep Inn & Suites University/Shands and Country Inn & Suites by Radisson, Gainesville, FL. See all available top hotels, or vacation rentals in Santa Fe.
What are some of the best vacation rentals in Santa Fe?
5BR UF Family Retreat with Private Pool, Pond, Game Room ā€“ Sleeps 10: This vacation home rental outside of Santa Fe is located on a lake and has an outdoor pool, a fireplace, and a barbecue grill to put you at ease in your new surroundings. It has 5 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. It offers a patio, a garden, and a selection of games so you can immerse yourself in your vacation. See all vacation rentals in Santa Fe.
If I need to cancel my hotel reservation in Santa Fe, will I receive a refund?
Yes, most hotel bookings are fully refundable if cancelled before the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you have a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Fe.
Where can I learn more about changing or cancelling my trip to Santa Fe?
To access more information about picking new dates or cancelling your trip to Santa Fe, go to https://www.expedia.com/service/.
What is staying in Santa Fe like?
Travelers to Santa Fe will find plenty to explore and enjoy. There are 796 hotels and other accommodations in the surrounding area. Find out more about Santa Fe.
What are the top places to visit in Santa Fe?
Places to visit in the wider area include Turkey Creek Golf Course, O'Leno State Park, and San Felasco Hammock Preserve State Park. You'll also find Devil's Milhopper Geological State Park and Gainesville Raceway in the area. Check out what more to see and do in Expedia's Santa Fe guide.
What's the seasonal weather like in Santa Fe?
The hottest months are usually July and August with an average temp of 80Ā°F, while the coldest months are January and February with an average of 59Ā°F. The rainiest months in Santa Fe are August, June, July, and September, with each month seeing an average of 7 inches of rainfall.

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