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Our top choices for Mississippi River hotels

River's Edge Motel

River's Edge Motel
2.0 star property
13.6 km from Mississippi River
9.0 out of 10, Wonderful, (366 reviews)
"We were just driving through and needed a place to stay for the night. It was an easy check in and very friendly staff so perfect for us."
United States
Brent
The price is ¥12,823
¥14,559 total
includes taxes & fees
Jun 7 - Jun 8
River's Edge Motel

The Eagles Nest Inn

The Eagles Nest Inn
3.0 star property
14.2 km from Mississippi River
9.4 out of 10, Exceptional, (25 reviews)
"Very nice place to stay loved the brick walls and wood floors leading up to the rooms"
United States
Gary
The price is ¥17,031
¥19,336 total
includes taxes & fees
Jun 19 - Jun 20
The Eagles Nest Inn

Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal
2.5 star property
26.3 km from Mississippi River
6.4 out of 10, (769 reviews)
"The staff were very friendly and helpful, The breakfast was probably the best we had experienced at any hotel where we have stayed. If we pass through the area again, we will likely choose to stay there again."
United States
Carol
The price is ¥10,098
¥11,728 total
includes taxes & fees
Jun 7 - Jun 8
Baymont by Wyndham Hannibal

Best Western On The River

Best Western On The River
2.5 star property
25.3 km from Mississippi River
8.6 out of 10, Excellent, (1,005 reviews)
"Clean rooms, decent breakfast"
United States
Christina
The price is ¥17,694
¥20,409 total
includes taxes & fees
Jun 28 - Jun 29
Best Western On The River

Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
2.5 star property
30.3 km from Mississippi River
9.6 out of 10, Exceptional, (1,002 reviews)
"Good breakfast"
United States
Neah
The price is ¥19,644
¥22,855 total
includes taxes & fees
Jun 28 - Jun 29
Sleep Inn & Suites Hannibal West

Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
25.8 km from Mississippi River
9.0 out of 10, Wonderful, (30 reviews)
"Fun themed rooms."
United States
Kelly
The price is ¥27,386
¥37,137 total
includes taxes & fees
Jun 7 - Jun 8
Lighthouse Inn & Suites

Economy Inn Wentzville

Economy Inn Wentzville
2.0 star property
86.8 km from Mississippi River
6.4 out of 10, (544 reviews)
"Room was clean but basic"
United States
James
The price is ¥11,220
¥12,730 total
includes taxes & fees
Jun 7 - Jun 8
Economy Inn Wentzville

Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
2.5 star property
26.2 km from Mississippi River
7.6 out of 10, Good, (698 reviews)
"Beds comfortable- nice breakfast choices. A pleasant peaceful setting "
United States
Wanda J
The price is ¥16,750
¥19,802 total
includes taxes & fees
Jun 14 - Jun 15
Comfort Inn & Suites - Hannibal

Motel 6 Hannibal, MO

Motel 6 Hannibal, MO
2.0 star property
26.1 km from Mississippi River
7.4 out of 10, Good, (1,005 reviews)
"Nice staff, good parking, clean room."
United States
Susan
The price is ¥8,654
¥9,982 total
includes taxes & fees
Jun 14 - Jun 15
Motel 6 Hannibal, MO

Garden House Bed and Breakfast

Garden House Bed and Breakfast
2.0 star property
25.2 km from Mississippi River
8.4 out of 10, Very Good, (43 reviews)
"Very welcoming hosts, they went the extra mile and had a very comfortable bed! There were lots of cool antiques and they knew a lot of history on the home itself. We would recommend staying here again. "
United States
Andy Nicole
The price is ¥17,092
¥19,718 total
includes taxes & fees
Jun 10 - Jun 11
Garden House Bed and Breakfast

Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal
2.0 star property
26.3 km from Mississippi River
7.2 out of 10, Good, (1,002 reviews)
"Property was clean and staff was friendly."
United States
Etta
The price is ¥10,661
¥12,298 total
includes taxes & fees
Jun 22 - Jun 23
Super 8 by Wyndham Hannibal

Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal
2.0 star property
26.4 km from Mississippi River
7.4 out of 10, Good, (249 reviews)
"A good place to stay in Hannibal."
United States
Marcia
The price is ¥10,900
¥12,573 total
includes taxes & fees
Jun 21 - Jun 22
Days Inn by Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal
2.0 star property
26.3 km from Mississippi River
7.4 out of 10, Good, (168 reviews)
"The room was clean . The staff was helpful on things to do in the area. It was a very relaxing and the town was beautiful"
United States
Samantha
The price is ¥9,898
¥11,496 total
includes taxes & fees
Jun 11 - Jun 12
Howard Johnson BY Wyndham Hannibal

Baymont by Wyndham Keokuk

Baymont by Wyndham Keokuk
2.5 star property
96.1 km from Mississippi River
6.2 out of 10, (517 reviews)
"I would book this same hotel again . It’s older, but very accommodating. "
United States
Michael
The price is ¥11,829
¥13,249 total
includes taxes & fees
Jun 7 - Jun 8
Baymont by Wyndham Keokuk

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
2.5 star property
30 km from Mississippi River
8.0 out of 10, Very Good, (1,005 reviews)
"Parking was easy and safe, when the staff was available, they were courteous, and breakfast was good."
United States
Dan
The price is ¥13,309
¥15,486 total
includes taxes & fees
Jun 28 - Jun 29
Quality Inn & Suites Hannibal West

LAKEVIEWINN

LAKEVIEWINN
2.5 star property
89.4 km from Mississippi River
5.6 out of 10, (50 reviews)
"It’s okay and decently priced"
United States
Krischel
The price is ¥9,829
¥11,102 total
includes taxes & fees
Jun 14 - Jun 15
LAKEVIEWINN

La Quinta Inn & Suites by Wyndham St. Louis Hazelwood/ North

La Quinta Inn & Suites by Wyndham St. Louis Hazelwood/ North
3.0 star property
109.6 km from Mississippi River
6.6 out of 10, (1,007 reviews)
"Great stay"
United States
Micaela
The price is ¥11,308
¥13,822 total
includes taxes & fees
Jun 14 - Jun 15
La Quinta Inn & Suites by Wyndham St. Louis Hazelwood/ North

Sleep Inn Saint Charles North

Sleep Inn Saint Charles North
2.5 star property
97.1 km from Mississippi River
5.8 out of 10, (541 reviews)
"I enjoy my fligth"
United States
Eulogio
The price is ¥12,099
¥13,905 total
includes taxes & fees
Jul 3 - Jul 4
Sleep Inn Saint Charles North

Extended Stay America Select Suites St Louis Earth City

Extended Stay America Select Suites St Louis Earth City
2.5 star property
107.1 km from Mississippi River
6.6 out of 10, (910 reviews)
"Not a bad place"
United States
Robert
The price is ¥14,857
¥17,750 total
includes taxes & fees
Jun 21 - Jun 22
Extended Stay America Select Suites St Louis Earth City

Motel 6 Maryland Heights, MO

Motel 6 Maryland Heights, MO
2.0 star property
111 km from Mississippi River
6.2 out of 10, (1,005 reviews)
"Stay was ok, room wasn't the best but was clean and staff helpful"
United States
Bradley
The price is ¥9,617
¥11,155 total
includes taxes & fees
Jun 10 - Jun 11
Motel 6 Maryland Heights, MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Mississippi River

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Property grounds
River's Edge Motel
2.0 star property
9.0
Wonderful
366 reviews
View
Lunch and dinner served
The Eagles Nest Inn
3.0 star property
9.4
Exceptional
25 reviews
View
Indoor pool
Baymont by Wyndham Hannibal
2.5 star property
6.4
769 reviews
View
Desk, iron/ironing board, WiFi, bed sheets
Best Western On The River
2.5 star property
8.6
Excellent
1,005 reviews
View
Exterior
Sleep Inn & Suites Hannibal West
2.5 star property
9.6
Exceptional
1,002 reviews
View

Top Mississippi River Hotel Reviews

Hotels near other Mississippi River attractions

Frequently asked questions

What's the area like around Mississippi River?
Mississippi River is located in an area that travelers like for its baseball games. When you want to settle in and find a place to stay, check out some of the hotels and other accommodations that Expedia offers in the area.
What's the best place to stay close to Mississippi River?
Hyatt Regency St. Louis at The Arch is one of the top choices for your stay based on our traveler data, and this hotel offers 3 restaurants and 2 bars. You'll find it 82.1 mi (132.1 km) from Mississippi River. Other good options around the area include Pear Tree Inn St. Louis Airport and Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham.
If I need to cancel the hotel reservation for my stay near Mississippi River, will I receive a refund?
Yes, you'll find most hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get top deals close to Mississippi River.
Where can I learn more about changing or cancelling my trip in the area near Mississippi River?
For additional details about updating your stay near Mississippi River or cancelling it, head over to our customer service page.