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Our top choices for Mississippi River hotels

River's Edge Motel

River's Edge Motel
2.0 star property
13.6 km from Mississippi River
9.0 out of 10, Wonderful, (359 reviews)
"Excellent stay !!! Quite "
United States
Bradley
The price is ¥12,259
¥13,919 total
includes taxes & fees
Mar 3 - Mar 4
River's Edge Motel

The Eagles Nest Inn

The Eagles Nest Inn
3.0 star property
14.2 km from Mississippi River
9.4 out of 10, Exceptional, (21 reviews)
"Room was spacious and clean. Had a great stay. The restaurant was delicious. "
United States
James
The price is ¥14,774
¥16,773 total
includes taxes & fees
Feb 13 - Feb 14
The Eagles Nest Inn

Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal
2.5 star property
26.3 km from Mississippi River
6.4 out of 10, (740 reviews)
"The staff was very welcoming and the room was clean "
United States
Tracy
The price is ¥8,965
¥10,365 total
includes taxes & fees
Feb 17 - Feb 18
Baymont by Wyndham Hannibal

Best Western On The River

Best Western On The River
2.5 star property
25.3 km from Mississippi River
8.6 out of 10, Excellent, (1,001 reviews)
"Everything was great. Will definitely stay again."
United States
Ethan
The price is ¥10,011
¥11,499 total
includes taxes & fees
Feb 15 - Feb 16
Best Western On The River

Riverside Inn Hannibal

Riverside Inn Hannibal
2.5 star property
25.1 km from Mississippi River
9.4 out of 10, Exceptional, (167 reviews)
"Great place to stay!"
United States
Sandy
The price is ¥21,803
¥30,320 total
includes taxes & fees
Feb 20 - Feb 21
Riverside Inn Hannibal

Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
2.5 star property
30.3 km from Mississippi River
9.6 out of 10, Exceptional, (1,002 reviews)
"Desk staff very nice, clean room, very nice facility!"
United States
Peg
The price is ¥15,157
¥17,559 total
includes taxes & fees
Feb 22 - Feb 23
Sleep Inn & Suites Hannibal West

Super 8 by Wyndham O'Fallon MO/St. Louis Area

Super 8 by Wyndham O'Fallon MO/St. Louis Area
2.0 star property
90.7 km from Mississippi River
6.8 out of 10, (1,000 reviews)
"Staff was awesome and accomodating. Room and price was great. "
United States
Anthony
The price is ¥9,719
¥11,464 total
includes taxes & fees
Feb 19 - Feb 20
Super 8 by Wyndham O'Fallon MO/St. Louis Area

Economy Inn Wentzville

Economy Inn Wentzville
2.0 star property
86.8 km from Mississippi River
6.4 out of 10, (517 reviews)
"The heating unit was noise, the sink was plumbed backwards but the room was clean."
United States
Gordon
The price is ¥9,194
¥10,431 total
includes taxes & fees
Feb 14 - Feb 15
Economy Inn Wentzville

Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
25.8 km from Mississippi River
8.8 out of 10, Excellent, (25 reviews)
"Nice room. Matched the pictures. Exactly what we were looking for."
United States
John
The price is ¥25,876
¥29,716 total
includes taxes & fees
Feb 17 - Feb 18
Lighthouse Inn & Suites

Garden House Bed and Breakfast

Garden House Bed and Breakfast
2.0 star property
25.2 km from Mississippi River
8.6 out of 10, Excellent, (38 reviews)
"Great location. Clean rooms, Staff very friendly."
United States
Charles
The price is ¥16,412
¥18,849 total
includes taxes & fees
Feb 20 - Feb 21
Garden House Bed and Breakfast

Relax Inn Saint Charles

Relax Inn Saint Charles
2.0 star property
98 km from Mississippi River
6.8 out of 10, (1,000 reviews)
"Clean room very nice staff it’s nice"
United States
Mercedez
The price is ¥9,461
¥10,873 total
includes taxes & fees
Feb 22 - Feb 23
Relax Inn Saint Charles

Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
2.5 star property
26.2 km from Mississippi River
7.6 out of 10, Good, (673 reviews)
"Everything was clean and staff was friendly. Just needed some updates. "
United States
Georgia
The price is ¥11,125
¥13,243 total
includes taxes & fees
Feb 22 - Feb 23
Comfort Inn & Suites - Hannibal

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
2.5 star property
30 km from Mississippi River
8.0 out of 10, Very Good, (1,007 reviews)
"Good breakfast selections. Close to a good restaurant. "
United States
Steve
The price is ¥11,461
¥13,278 total
includes taxes & fees
Mar 9 - Mar 10
Quality Inn & Suites Hannibal West

Motel 6 Hannibal, MO

Motel 6 Hannibal, MO
2.0 star property
26.1 km from Mississippi River
7.4 out of 10, Good, (1,001 reviews)
"Overall, very nice stay"
United States
Cary
The price is ¥8,427
¥9,677 total
includes taxes & fees
Mar 3 - Mar 4
Motel 6 Hannibal, MO

Days Inn by Wyndham St Peters/St Charles

Days Inn by Wyndham St Peters/St Charles
2.0 star property
93.8 km from Mississippi River
6.2 out of 10, (1,000 reviews)
"Room was excellent and clean"
United States
catherine
The price is ¥8,467
¥9,733 total
includes taxes & fees
Feb 15 - Feb 16
Days Inn by Wyndham St Peters/St Charles

Baymont by Wyndham Keokuk

Baymont by Wyndham Keokuk
2.5 star property
96.1 km from Mississippi River
6.2 out of 10, (497 reviews)
"Great location for geode hunting. Irish Pub behind the hotel is the best."
United States
Marty
The price is ¥8,761
¥9,813 total
includes taxes & fees
Feb 22 - Feb 23
Baymont by Wyndham Keokuk

Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal
2.0 star property
26.3 km from Mississippi River
7.2 out of 10, Good, (1,000 reviews)
"clean room - soft beds - friendly staff - very welcoming - lobby nice"
United States
Maxine
The price is ¥8,807
¥10,115 total
includes taxes & fees
Feb 22 - Feb 23
Super 8 by Wyndham Hannibal

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North
3.0 star property
109.6 km from Mississippi River
6.6 out of 10, (1,000 reviews)
"Great staff and the place is nice and clean and the breakfast is awesome."
United States
Kerry
The price is ¥9,062
¥11,076 total
includes taxes & fees
Mar 1 - Mar 2
La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North

LAKEVIEWINN

LAKEVIEWINN
2.5 star property
89.4 km from Mississippi River
5.6 out of 10, (34 reviews)
"I enjoyed it! And the owners were so sweet and understanding. I would absolutely stay there again!"
United States
Evelyn
The price is ¥10,344
¥11,683 total
includes taxes & fees
Feb 22 - Feb 23
LAKEVIEWINN

Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal
2.0 star property
26.3 km from Mississippi River
7.2 out of 10, Good, (153 reviews)
"Yes my stay was great"
United States
Aaron
The price is ¥8,735
¥10,102 total
includes taxes & fees
Mar 3 - Mar 4
Howard Johnson BY Wyndham Hannibal
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Mississippi River

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Property grounds
River's Edge Motel
2.0 star property
9.0
Wonderful
359 reviews
View
Interior
The Eagles Nest Inn
3.0 star property
9.4
Exceptional
21 reviews
View
Indoor pool
Baymont by Wyndham Hannibal
2.5 star property
6.4
740 reviews
View
Desk, iron/ironing board, WiFi, bed sheets
Best Western On The River
2.5 star property
8.6
Excellent
1,001 reviews
View
Honeymoon Room, River View | Egyptian cotton sheets, premium bedding, pillowtop beds
Riverside Inn Hannibal
2.5 star property
9.4
Exceptional
167 reviews
View

Top Mississippi River Hotel Reviews

Hotels near other Mississippi River attractions

Frequently asked questions

What's the area like around Mississippi River?
Mississippi River is located in an area that travelers like for its baseball games. When you want to settle in and find a place to stay, check out some of the hotels and other accommodations that Expedia offers in the area.
What's the best place to stay close to Mississippi River?
Clayton Plaza Hotel & Extended Stay is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. You'll find it 76 mi (122.3 km) from Mississippi River. Other good options around the area include 21C Museum Hotel St Louis and Hilton St. Louis Airport.
If I need to cancel the hotel reservation for my stay near Mississippi River, will I receive a refund?
Yes, you'll find most hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get top deals close to Mississippi River.
Where can I learn more about changing or cancelling my trip in the area near Mississippi River?
For additional details about updating your stay near Mississippi River or cancelling it, head over to our customer service page.