A bridge spanning a body of water with a city skyline in the background during sunset.

Find hotels near Mississippi River, from ¥12,698

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Aug 23 - Aug 24
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Our top choices for Mississippi River hotels

1. Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
30.3 km from Mississippi River
United States
Steve
¥18,780
¥21,850 total
includes taxes & fees
Sep 13 - Sep 14
Sleep Inn & Suites Hannibal West

2. River's Edge Motel

River's Edge Motel
13.6 km from Mississippi River
United States
Payton
¥12,716
¥14,437 total
includes taxes & fees
Aug 26 - Aug 27
River's Edge Motel

3. The Eagles Nest Inn

The Eagles Nest Inn
14.2 km from Mississippi River
United States
Gary
¥17,882
¥20,304 total
includes taxes & fees
Aug 25 - Aug 26
The Eagles Nest Inn

4. Riverside Inn Hannibal

Riverside Inn Hannibal
25.1 km from Mississippi River
United States
Jack
¥25,351
¥34,743 total
includes taxes & fees
Sep 14 - Sep 15
Riverside Inn Hannibal

5. Best Western On The River

Best Western On The River
25.3 km from Mississippi River
United States
Carolyn
¥17,483
¥20,166 total
includes taxes & fees
Aug 25 - Aug 26
Best Western On The River

6. Oak Hill Inn & Suites

Oak Hill Inn & Suites
71.8 km from Mississippi River
United States
Candace
¥16,092
¥18,341 total
includes taxes & fees
Aug 24 - Aug 25
Oak Hill Inn & Suites

7. Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
30 km from Mississippi River
United States
James
¥10,930
¥12,717 total
includes taxes & fees
Aug 30 - Aug 31
Quality Inn & Suites Hannibal West

8. Heritage Hotel Quincy

Heritage Hotel Quincy
47.8 km from Mississippi River
United States
Dustine
¥11,141
¥12,698 total
includes taxes & fees
Aug 31 - Sep 1
Heritage Hotel Quincy

9. Holiday Inn Express & Suites Wentzville St Louis West by IHG

Holiday Inn Express & Suites Wentzville St Louis West by IHG
86.2 km from Mississippi River
United States
Karen
¥21,458
¥25,568 total
includes taxes & fees
Aug 30 - Aug 31
Holiday Inn Express & Suites Wentzville St Louis West by IHG

10. Drury Inn & Suites St. Louis St. Peters

Drury Inn & Suites St. Louis St. Peters
95.3 km from Mississippi River
United States
Melanie
¥17,483
¥20,096 total
includes taxes & fees
Aug 30 - Aug 31
Drury Inn & Suites St. Louis St. Peters

11. Holiday Inn Quincy East by IHG

Holiday Inn Quincy East by IHG
46.1 km from Mississippi River
United States
Debra
¥18,438
¥21,015 total
includes taxes & fees
Sep 20 - Sep 21
Holiday Inn Quincy East by IHG

12. Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles
104 km from Mississippi River
United States
Rebecca
¥22,251
¥25,794 total
includes taxes & fees
Aug 30 - Aug 31
Drury Plaza Hotel St. Louis St. Charles

13. Quality Inn & Suites Quincy - Downtown

Quality Inn & Suites Quincy - Downtown
47.8 km from Mississippi River
United States
leon
¥19,023
¥21,682 total
includes taxes & fees
Sep 23 - Sep 24
Quality Inn & Suites Quincy - Downtown

14. Lighthouse Inn & Suites

Lighthouse Inn & Suites
25.8 km from Mississippi River
United States
Kari
¥28,528
¥32,907 total
includes taxes & fees
Aug 24 - Aug 25
Lighthouse Inn & Suites

15. Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
26.2 km from Mississippi River
United States
Tracey
¥12,190
¥14,539 total
includes taxes & fees
Aug 30 - Aug 31
Comfort Inn & Suites - Hannibal

16. Hampton Inn & Suites St. Louis/Alton

Hampton Inn & Suites St. Louis/Alton
110.3 km from Mississippi River
United States
Willie
¥20,724
¥23,621 total
includes taxes & fees
Aug 30 - Aug 31
Hampton Inn & Suites St. Louis/Alton

17. TownePlace Suites by Marriott Wentzville

TownePlace Suites by Marriott Wentzville
86.6 km from Mississippi River
United States
Adrian
¥24,184
¥28,509 total
includes taxes & fees
Aug 30 - Aug 31
TownePlace Suites by Marriott Wentzville

18. Stoney Creek Inn Quincy

Stoney Creek Inn Quincy
46.5 km from Mississippi River
United States
Axel
¥18,279
¥20,835 total
includes taxes & fees
Sep 20 - Sep 21
Stoney Creek Inn Quincy

19. Holiday Inn Express & Suites St Peters by IHG

Holiday Inn Express & Suites St Peters by IHG
93.3 km from Mississippi River
United States
Serah
¥17,643
¥21,253 total
includes taxes & fees
Sep 20 - Sep 21
Holiday Inn Express & Suites St Peters by IHG

20. Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
103.7 km from Mississippi River
United States
Susan Greening.
¥21,452
¥24,653 total
includes taxes & fees
Aug 30 - Aug 31
Country Inn & Suites by Radisson, St. Charles Historic District
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Compare popular hotels close to Mississippi River

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A Sleep Inn & Suites building with a covered entrance, stone facade, and a flag.
Sleep Inn & Suites Hannibal West
9.6
Exceptional
1,003 reviews
View
A gazebo with a table and benches, surrounded by trees and a body of water.
River's Edge Motel
9.0
Wonderful
384 reviews
View
A restaurant with a bar area, wooden flooring, checkered tablecloths, and a brick wall.
The Eagles Nest Inn
9.4
Exceptional
26 reviews
View
A room with a beige leather sofa, a wooden coffee table, a floor lamp, and a patterned carpet.
Riverside Inn Hannibal
9.6
Exceptional
192 reviews
View
A hotel room with a large bed, a separate bathroom with a bathtub, and a desk with a chair.
Best Western On The River
8.6
Excellent
1,006 reviews
View

Top Mississippi River Hotel Reviews

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

10/10 Excellent
"Good location to events nice shuttle worth the money room clean ."
Laura 2-night trip
Posted 3 hours ago
Hollywood Casino & Hotel St. Louis
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent
"We truly enjoyed the location of the hotel , as the arch was right behind it ( walk out the door and there is the arch ) ! We was able to walk to the casino and to the Busch stadium for the concert . We felt safe at this location . The rooms were clean and comfortable . We had a 10 th floor interior with 2 queen beds and sofa sleeper . Only thing is the main area was cool but the bedroom don’t cool down much at all so we was sweating at night time . The breakfast and kickback was good as well . We will definitely stay again"
Stacey 1-night trip
Posted 4 hours ago
Drury Plaza Hotel St. Louis at the Arch
 The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

10/10 Excellent
"1. You can park for free from 7 pm to 8 am across the streets to the west and north, and during other times I paid about $2.65 per hour. 2. The pool was a thrill and I thought "the best $25 (resort fee) I ever spent. 3. We were given a coupon for two free drinks in the bar, and got two glasses of wine - filled to the top - I have never seen any place fill a wine glass to the top! 4. The room was a suite, and huge, and they gave us the 9th floor looking south. I could sit on the couch and look out over Forest Park. 5. The bed was super comfortable. 6. We considered the Indigo and another, but for the night we wanted the rate was only maybe $50 more a night, so we splurged for this. 7. On the first floor there is a hallway through the residential building north of this, out to Maryland Place, a fun area to walk, and a guard sits at that door who can sort of watch your car. 8. The business center is just one computer and printer beyond the check in counter and one has to stand to use it, but that was ok. 9. A new building is being constructed across the street to the south, and there is a very low rumble of noise starting around 6:30 a.m., so do be aware of that if you want to sleep later, but it was a very low and distant sound, and only when a truck came in or something, I almost had to strain to hear it. 10. This is one of the Historic Hotels of America, and you can save 15% on the Sonesta website by joining that, but then the rate is the same as on Expedia"
Seth 2-night trip
Posted 7 hours ago
The Royal Sonesta Chase Park Plaza St. Louis
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

10/10 Excellent
"This is our second time staying at the hotel. The hotel staff were very proactive in fixing our bathroom when there was an issue. They have breakfast included in the tariff, but we did not partake in it. They have an evening beer and wine time with chips, popcorn etc. That was a nice touch! The shuttles are very convenient to get to and from the airport!"
Sangeetha 6-night trip
Posted 7 hours ago
Pear Tree Inn St. Louis Airport
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

10/10 Excellent
"We we're staying 2 nights in the hotel and we booked the second night a little closer to our trip so the room was a little different. I really wanted to stay in the same room so we didn't have to lug our stuff to the car and check back in when it was time for check in so I asked the front desk if it was possible to stay in the same room. He said yes and checked us out and right back in right there. It was a great stay, and the breakfast was good also the pool. We we're headed to the aquarium and it was only a short walk. We will definitely be staying again."
Rachael 1-night trip
Posted 10 hours ago
Pear Tree Inn St. Louis Near Union Station
Forest Park Hotel by MDR

Forest Park Hotel by MDR

10/10 Excellent
"Perfect place to stay and affordable 👌 ✨️ close to downtown and other fun places to visit.."
wahwah 1-night trip
Posted 14 hours ago
Forest Park Hotel by MDR
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

10/10 Excellent
"Amazing staff, made my 30th a night to remember. The front desk lady had me laughing out my knees. Friendly and accommodating 10/10 would recommend"
Ashley 3-night trip
Posted 17 hours ago
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Drury Inn & Suites St. Louis Airport

Drury Inn & Suites St. Louis Airport

10/10 Excellent
"Amazing staff&stay. Great location near UMSL- what a way to give a parent ease for freshman drop off!!! Thank you"
Candace 2-night trip
Posted 17 hours ago
Drury Inn & Suites St. Louis Airport
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

10/10 Excellent
"Room was a great size for the money. Hotel was clean and quiet and easy to access from the garage. Great pool as well."
Stephanie 2-night trip
Posted 3 days ago
Ameristar Casino Resort and Spa

Other attractions near Mississippi River

Mark Twain Cave

8.8/10 (89 reviews)
You can find out about the history of Hannibal with a visit to Mark Twain Cave. While in this family-friendly area, you can savor the top-notch restaurants.
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Sawyer's Creek Fun Park

7.8/10 (16 reviews)
Explore the great outdoors at Sawyer's Creek Fun Park, a lovely green space in Hannibal. While in this walkable area, you can savor the top-notch restaurants.
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Lovers Leap

8.8/10 (171 reviews)
Find out about the history of Hannibal with a stop at Lovers Leap. While in this walkable area, you can savor the top-notch restaurants.
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Sodalis Nature Preserve

Explore the great outdoors at Sodalis Nature Preserve, a lovely green space in Hannibal. While in this family-friendly area, you can savor the top-notch restaurants.
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Bluff City Theater

7.6/10 (5 reviews)
Enjoy a show at Bluff City Theater, a theater with a story to tell in Hannibal. While in this walkable area, you can savor the top-notch restaurants.
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Planters Barn Theater

8.8/10 (22 reviews)
Enjoy a show at Planters Barn Theater, a storied theater in Hannibal. While in this walkable area, you can savor the top-notch restaurants.
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Big River Train Town

8.0/10 (25 reviews)
You can browse the exhibits at Big River Train Town, a museum with a story of its own, during your travels to Hannibal. While in this family-friendly area, you can savor the top-notch restaurants.
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Mark Twain Boyhood Home and Museum

9.0/10 (278 reviews)
Find out about the history of Hannibal when you take a trip to Mark Twain Boyhood Home and Museum. While in this walkable area, you can savor the top-notch restaurants.
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Find out more about Mississippi River

Top reasons to visit Mississippi River

  • Vibrant Activities: Enjoy baseball games, live music, and sports events along the river.
  • Scenic Day Trips: Experience breathtaking landscapes and explore charming towns like Minneapolis and the Mississippi Delta.
  • Historic Exploration: Visit historic houses, museums, and engage in river studies for an educational adventure.
  • Steamboat Cruises: Take a ride on iconic steamboats for a unique view of this majestic waterway.
  • Diverse Accommodations: Choose from cozy bed & breakfasts to modern hotels for a perfect stay.

Find great hotels near Mississippi River

Discover a range of charming accommodations along the majestic Mississippi River, from cozy bed & breakfasts to modern hotels. Whether you're seeking a family-friendly retreat, a pet-friendly getaway, or a romantic escape, you're sure to find the perfect place to relax. Explore options like the Hampton Inn and unique wilderness cabins, all designed to enhance your experience in this beautiful region.

  • Best Western On The River: Located in the heart of the city, Best Western On The River offers a budget-friendly stay with a family-oriented atmosphere. With a guest rating of 8.6 out of 10, this hotel is ideal for both business and leisure travelers. Enjoy amenities designed for families, including a PoolGate for children's safety. The convenient city center location provides easy access to local attractions, making it a practical choice for those looking to explore the area while enjoying comfortable accommodations.
  • Super 8 by Wyndham Bowling Green: Super 8 by Wyndham Bowling Green is a cozy and budget-friendly motel located 24km from the Mississippi River, boasting a guest rating of 8.4 out of 10. Guests can start their day with complimentary breakfast options, including a daily breakfast and to-go breakfasts. The motel also features entertainment amenities such as DVD players and televisions with premium channels, ensuring a relaxing stay for travelers. This welcoming environment caters well to those looking for both comfort and convenience.
  • River's Edge Motel: Offering a unique pet-friendly experience, River's Edge Motel is just 13km from the Mississippi River and has garnered a guest rating of 9.0 out of 10. This budget-friendly motel welcomes pets with certain restrictions, making it a great choice for travelers who wish to bring their furry companions along. The property ensures a comfortable stay with its friendly atmosphere and is an excellent option for those seeking a relaxing getaway close to nature.

Where to stay near Mississippi River

Embark on an unforgettable journey along the majestic Mississippi River, where friendly locals and family-friendly activities await. Explore vibrant cities like Minneapolis, rich in culture and history, or relax in the serene beauty of the Mississippi Delta. Don't miss the chance to discover the scenic Iowa River and the picturesque Minnesota River, both offering excellent opportunities for excursions and relaxation amidst nature's splendor.

  • Louisiana: A charming city located 14km from the Mississippi River, Louisiana offers a delightful blend of outdoor activities and scenic beauty. This city attracts visitors year-round, with peak seasons in April, July, and September. Here, you can indulge in romantic strolls along the river or explore the tranquil lakes and nearby national parks. Louisiana is also home to various recreational areas, theaters, and entertainment facilities, making it a perfect destination for those seeking an enriching travel experience.
  • New Canton: Situated 11km from the Mississippi River, New Canton is a family-friendly city known for its seasonal visitor influx. Peak travel times occur between January to February, April, August, and November. Families flock to New Canton for its outdoor adventures, scenic landscapes, and educational opportunities. With golf courses and a natural history museum within reach, it’s an ideal spot for those looking to combine fun and learning during their vacation. The picturesque river and lake further enhance the city's appeal.
  • Rockport: Located 13km from the Mississippi River, Rockport is a vibrant city that offers a mix of family-oriented and city-themed experiences. This destination sees its highest visitor numbers in May, July, and September. Rockport features numerous educational venues, theaters, and golf facilities, catering to diverse interests. Local attractions include an urban park, a history museum, and a modern college university, providing plenty of opportunities for exploration and engagement. The city’s welcoming atmosphere makes it a fantastic place for making lasting memories.

Things to do in Mississippi River

Shopping

In the Mississippi River region, visit the River Market in Little Rock for local crafts and unique souvenirs. If you're up for a drive, check out the Mall of America in Bloomington, located over 16km away, featuring a wide array of shops and entertainment options.

Recreation

The Riverbend Wellness Center offers rejuvenating yoga classes and meditation sessions overlooking the Mississippi River. Nearby, the Natchez Trace Parkway invites visitors to explore scenic trails, ideal for hiking and cycling amidst nature's beauty, promoting relaxation and mindfulness.

Adventure

Explore the Mississippi River on a guided kayak tour, where you can paddle through scenic waterways and witness local wildlife. For a thrilling experience, try zip-lining above the river or take a riverboat cruise to enjoy panoramic views of the landscape and historic sites along the shore.

Nightlife

The nightlife along the Mississippi River features lively spots like the iconic Beale Street in Memphis, known for its blues clubs, and the vibrant bars in New Orleans' French Quarter, where jazz fills the air. Enjoy craft cocktails at rooftop lounges or savor local cuisine at late-night eateries.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions near Mississippi River

The Mississippi River offers a variety of attractions for every type of traveler, including historic houses, caves, and museums. Visitors can immerse themselves in culture and adventure while exploring the Mississippi embayment, river corridor, and the stunning landscapes along the river. Don't miss the chance to experience the fascinating Mississippi River Project and take a ride on the iconic steamboats that cruise this amazing waterway.

  • Mark Twain Boyhood Home and Museum: Explore the charming home where the famous author grew up. The museum showcases artifacts and exhibits that reflect the culture and history of Twain's formative years, offering a glimpse into the life that inspired beloved tales.
  • Mark Twain Cave: Venture into the depths of this fascinating cave, which offers an adventurous experience amid stunning natural formations. Guided tours provide insights into the cave's history and its connection to Twain's stories, making it a thrilling outdoor activity.
  • Mark Twain Memorial Lighthouse: Visit this historic lighthouse that stands as a tribute to the literary legend. Enjoy scenic views of the river and learn about Twain's impact on American literature, all while soaking in the cultural significance of the site.

The nearest major airports for your trip to Mississippi River

Flying into the Mississippi River region is convenient with several major airports nearby. St. Louis Lambert International Airport (STL) is 113km away, offering luxurious hotels like The Ritz-Carlton and Ameristar Casino Resort, both 11km from the airport. Columbia Regional Airport (COU), located 122km from the river, features nearby options like The Broadway Columbia, also 18km away. For those considering Peoria International Airport (PIA), situated 175km from the river, the Embassy Suites is 8km away and provides transportation services to the airport. Each location offers a variety of accommodations to suit your travel needs.

Frequently asked questions

What's the area like around Mississippi River?
Mississippi River is located in an area that travelers like for its baseball games. When you want to settle in and find a place to stay, check out some of the hotels and other accommodations that Expedia offers in the area.
What's the best place to stay close to Mississippi River?
Hollywood Casino & Hotel St. Louis is one of the top choices for your stay based on our traveler data, and this hotel offers a casino and 7 restaurants. You'll find it 65.7 mi (105.7 km) from Mississippi River. Other good options around the area include Hyatt Regency St. Louis at The Arch and Clayton Plaza Hotel & Extended Stay.
If I need to cancel the hotel reservation for my stay near Mississippi River, will I receive a refund?
Yes, you'll find most hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get top deals close to Mississippi River.
Where can I learn more about changing or cancelling my trip in the area near Mississippi River?
For additional details about updating your stay near Mississippi River or cancelling it, head over to our customer service page.