Top Destination Hotels in James Island, SC from ￥31,342

A lighthouse on a pier extending into a calm body of water.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for James Island Destination Hotels

A resort with multiple swimming pools, lounge areas, and a fire pit.

A coastal town with beachfront properties and a marina.

A golf course with bunkers, a sand trap, and a building in the background.

A resort with multiple buildings, two swimming pools, and a beach area with sun loungers.

1. Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

Isle of Palms

John

￥23,157

￥31,342 total

includes taxes & fees

Nov 18 - Nov 19

A beachfront hotel with a pool, beach access, and a sunset view.

A balcony with a view of the ocean, furnished with yellow chairs and a table, and decorated with flowers and candles.

A coastal hotel with multiple buildings, a beach in the background, and surrounding greenery.

2. Wild Dunes Resort – Residences at Sweetgrass

Isle of Palms

Jeff

￥33,081

￥44,467 total

includes taxes & fees

Nov 15 - Nov 16

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Top James Island Hotel Reviews

The Francis Marion Hotel

10/10 Excellent

"Awesome!"

Drury Plaza Hotel North Charleston

10/10 Excellent

"Quite simply one of the finest lodging experiences of my life! Wonderful, welcoming staff who bend over backwards to “make your stay as good as possible!” No issues whatsoever. Room was beautiful. Food offerings were great. I will definitely look to stay there again sometime in the future."

The Ryder Hotel

10/10 Excellent

"We adored The Ryder! From the amenities, to the staff, everything was excellent."

The Charleston Place

10/10 Excellent

"Beautiful hotel. The breakfast restaurant was rather slow and when an issue arose did not deal with it as well as one would expect from a 5 star place. Their bar place also gets filled up quickly. Stay here but eat elsewhere."

Harborside at Charleston Harbor Resort and Marina

10/10 Excellent

"I really enjoyed the location and views."

The Palms Oceanfront Hotel

8/10 Good

"We really enjoyed our visit to IOP..The hotel is in a great location..We had a gorgeous view! The room was clean and the staff was very friendly and helpful.. The parking arrangement was not the best, and the bathroom was very small, but overall a pleasant stay."

The Cooper

10/10 Excellent

"Great location, awesome staff , clean and can’t wait to go back"

Cambria Hotel Mount Pleasant – Charleston

10/10 Excellent

"Staff was mostly friendly, rooms were very nice, modern and clean. The only thing I would say was a little off was the TV being adjacent to bed on a wall, and no streaming options was a little inconvenient if you planned on watching some TV in bed to unwind. Bar and staff was fantastic. Location to both Charleston and beaches like Isle of Palms is very reasonable, 25 minutes and 15 minutes respectively. I would stay there again if/when the price is right."