The Best Resorts & Hotels with Spas in Great Diamond Island, ME from ￥22,244 in 2026

A calm sea with a sailboat and rocky coastline.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check availability on Great Diamond Island Resorts & Hotels with Spas

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Great Diamond Island hotels with a spa

A hot tub area with a tiled floor, a wooden bench, a potted plant, and towels on a rack.

A brick building with a red awning labeled "Chateau Riverside."

A balcony with a table and chairs, overlooking a street with buildings and parked cars.

A restaurant with a brick fireplace, white chairs, and tables set for dining.

1. Portland Regency Hotel & Spa

Downtown Portland

Revitalize in a historic waterfront hotel with 7 treatment rooms offering aromatherapy and couples massages for a luxurious escape.

￥21,395

￥23,672 total

includes taxes & fees

Nov 1 - Nov 2

A hotel corridor with a modern design, featuring a glass railing, round tables with candles, and a view of the cityscape through the windows.

A spacious lounge with leather seating, round tables, and large windows offering a view of a body of water and buildings.

A modern hotel lobby with a large chandelier, reception desk, and a staircase leading to other areas.

A spacious bar area with wooden stools, a counter, and large windows offering a view of the outdoors.

2. The Westin Portland Harborview

Downtown Portland

Indulge in a serene retreat at this hotel with 4 treatment rooms offering deep-tissue massages, facials, and couples treatments.

￥20,105

￥22,244 total

includes taxes & fees

Nov 11 - Nov 12

A modern interior with a wooden sauna, a round table with books and cups, and wooden chairs.

A multi-story brick building with a flat roof, large windows, and outdoor seating areas.

A wellness spa interior with a reception desk, potted plants, and wellness-related posters.

A hotel room with a bed, a small table, and a window with curtains.

3. Longfellow Hotel

Parkside

Indulge in soulful relaxation at this elegant hotel with a full-service spa and tranquil nature reserve views.

￥29,778

￥39,069 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with a wooden door, a robe hanging on a hook, a bed with a brown quilt, a vanity with toiletries, and a small table with candles.

A backyard with a fire pit, wooden chairs, and a house with a porch.

A wooden pathway surrounded by lush greenery and flowers, leading to a row of houses with a staircase.

A covered porch with two wooden chairs and a view of a lake and greenery.

4. Inn By The Sea

Cape Elizabeth

Oceanfront spa sanctuary offers rejuvenating treatments amid coastal elegance.

￥52,161

￥61,194 total

includes taxes & fees

Nov 10 - Nov 11

View all properties

Choose what matters most at spa hotels in Great Diamond Island

Pool

Breakfast included

Hot tub

4 stars

5 stars

Top Great Diamond Island Hotel Reviews

Clarion Hotel Portland Airport ME

10/10 Excellent

"Very convenient to the airport for an early morning flight."

Holiday Inn Portland-By the Bay by IHG

10/10 Excellent

"We were in Portland for three (3) days on the tail end of our 2-week east coast trip. While the hotel is showing some signs of age, it did not disappoint and fully met our needs. The breakfast was great, especially the cook to order omelets. The hotel is not in the Old Port area but is still a comfortable 15-minute walk to get to the harbor area for dinner, bay tours and site seeing. The only negative was our last day and being awakened with two (2) room attendant staffers arguing in the hall. It lasted about 5 minutes until we came out into the hallway and glared at both of the participants. We will definitely stay here again when we come back either in 27 or 28."