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Discover 4,951 East San Mateo hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Residence Inn by Marriott San Francisco Airport/ San Mateo
Residence Inn by Marriott San Francisco Airport/ San Mateo

Hampton Inn & Suites San Mateo-San Francisco Airport
Hampton Inn & Suites San Mateo-San Francisco Airport

Hilton Garden Inn San Mateo
Hilton Garden Inn San Mateo

Extended Stay America Suites San Francisco San Mateo SFO
Extended Stay America Suites San Francisco San Mateo SFO

Holiday Inn Hotel & Suites San Mateo-San Francisco SFO by IHG
Holiday Inn Hotel & Suites San Mateo-San Francisco SFO by IHG

Inn@Bayshore
Inn@Bayshore
Where to stay in East San Mateo

Fisherman's Wharf
Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.

Union Square
Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

Downtown San Francisco
Serving as San Francisco's central business district, this area boasts Northern California's two tallest buildings, the Salesforce Tower and Transamerica Pyramid. Explore shopping malls like the Embarcadero Center and enjoy parks such as Sue Biermann Park, all easily accessible via Muni bus and rail lines.

South of Market
From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

Nob Hill
Luxury hotels, historic mansions, and Michelin-starred restaurants abound in this upscale area. Explore Union Square shopping district, Grace Cathedral, and the SF Masonic Auditorium for a taste of culture and history.
Top East San Mateo Hotel Reviews

Club Quarters Hotel in San Francisco
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