Find hotels in Mission District, San Francisco

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Our top choices for Mission District hotels

Union Hotel

Union Hotel
2.0 star property
Mission District
7.0 out of 10, Good, (291)
"Great for the price point. Friendly staff and quiet hotel."
United States
Michael
The price is ¥8,455
¥9,852 total
includes taxes & fees
Dec 29 - Dec 30
Union Hotel

1906 Mission

1906 Mission
2.0 star property
Mission District
8.0 out of 10, Very Good, (177)
"Property is fine on a budget but conditions outside make it u safe to walk around "
United States
Damian
The price is ¥14,248
¥16,571 total
includes taxes & fees
Dec 29 - Dec 30
1906 Mission

Noe's Nest Bed and Breakfast

Noe's Nest Bed and Breakfast
3.5 star property
Mission District
9.4 out of 10, Exceptional, (122)
"Staying at Noe’s Nest was amazing. The hosts were friendly and helpful. Breakfast was served at a communal table so there was friendly interaction with the other guests. Convenient location for Uber and Waymo pickups and BART was quite close. The rooms were filled with interesting and eclectic memorabilia. Guest rooms were comfy and quiet. I will stay there again."
United States
Susan
The price is ¥36,794
¥42,795 total
includes taxes & fees
Dec 30 - Dec 31
Noe's Nest Bed and Breakfast

Parker Guest House San Francisco

Parker Guest House San Francisco
3.5 star property
Mission District
9.6 out of 10, Exceptional, (455)
"Best place to stay! Beautiful decorations, felt like I was home for Christmas! "
United States
Alison
The price is ¥31,157
¥36,300 total
includes taxes & fees
Dec 29 - Dec 30
Parker Guest House San Francisco

Hotel Sunrise

Hotel Sunrise
2.0 star property
Mission District
6.8 out of 10, (637)
"Great place to stay in the heart of the Mission District. Spartan accomodations but excellent. Location is amazing. Dining options are limitless and it is so close to public transportation. "
United States
Brock
The price is ¥10,502
¥12,215 total
includes taxes & fees
Jan 10 - Jan 11, 2026
Hotel Sunrise

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf
4.0 star property
Fisherman's Wharf, 5.3 km from Mission District
9.0 out of 10, Wonderful, (7242)
"Great place to stay!"
United States
Isaiah
The price is ¥15,606
¥24,819 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Hotel Riu Plaza Fisherman's Wharf

Hotel Caza Fisherman's Wharf

Hotel Caza Fisherman's Wharf
4.0 star property
Fisherman's Wharf, 5.3 km from Mission District
9.0 out of 10, Wonderful, (3834)
"Excellent stay and great location! "
United States
CHRISTINE
The price is ¥19,830
¥30,526 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hotel Caza Fisherman's Wharf

The Mosser

The Mosser
3.0 star property
South of Market, 3 km from Mission District
8.0 out of 10, Very Good, (1003)
"room was perfect, the bed so comfy, the bedroom had a full bath which is hard to find in sf and for the price was good, also perfect location, personnel was kind i will come back "
Mexico
Miguel
The price is ¥9,864
¥11,590 total
includes taxes & fees
Jan 3 - Jan 4, 2026
The Mosser

Holiday Inn Express and Suites Fisherman's Wharf by IHG

Holiday Inn Express and Suites Fisherman's Wharf by IHG
3.0 star property
Fisherman's Wharf, 5.2 km from Mission District
9.0 out of 10, Wonderful, (2232)
"This was a very nice hotel. Clean, friendly staff, close to everything but also not in the middle of the business of San Francisco. I will definetly stay here again. "
United States
Christina
The price is ¥16,910
¥24,599 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Holiday Inn Express and Suites Fisherman's Wharf by IHG

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG
3.5 star property
Nob Hill, 3.4 km from Mission District
9.0 out of 10, Wonderful, (5044)
"Rooms were great, staff was great, location was great. "
United States
Jonathan
The price is ¥17,536
¥20,640 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Holiday Inn Golden Gateway by IHG

Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco
4.0 star property
Financial District, 4.2 km from Mission District
8.8 out of 10, Excellent, (2832)
"Clean room, friendly staff and good location"
United States
Jose Eduardo
The price is ¥15,701
¥18,479 total
includes taxes & fees
Dec 30 - Dec 31
Club Quarters Hotel in San Francisco

Hilton San Francisco Financial District

Hilton San Francisco Financial District
4.0 star property
Financial District, 4.1 km from Mission District
8.8 out of 10, Excellent, (2196)
"Great hotel "
United States
Tanya
The price is ¥17,204
¥20,248 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hilton San Francisco Financial District

Chancellor Hotel on Union Square

Chancellor Hotel on Union Square
3.5 star property
3.3 km from Mission District
9.4 out of 10, Exceptional, (3113)
"Great place to stay in the coty"
United States
Steve
The price is ¥11,858
¥14,011 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Chancellor Hotel on Union Square

Hotel Zephyr San Francisco

Hotel Zephyr San Francisco
4.0 star property
Fisherman's Wharf, 5.4 km from Mission District
8.6 out of 10, Excellent, (2338)
"Great location"
United States
Deborah
The price is ¥19,667
¥28,676 total
includes taxes & fees
Jan 26 - Jan 27, 2026
Hotel Zephyr San Francisco

Hotel Shattuck Plaza

Hotel Shattuck Plaza
4.0 star property
17.9 km from Mission District
8.8 out of 10, Excellent, (1093)
"Wonderful, will stay here again."
United States
Jennifer
The price is ¥21,841
¥25,160 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Hotel Shattuck Plaza

Handlery Union Square Hotel

Handlery Union Square Hotel
3.5 star property
Union Square, 3.2 km from Mission District
8.8 out of 10, Excellent, (2795)
"Clean hotel, great location, kind staff! "
United States
Felix
The price is ¥19,863
¥23,378 total
includes taxes & fees
Dec 29 - Dec 30
Handlery Union Square Hotel

Hilton San Francisco Airport Bayfront

Hilton San Francisco Airport Bayfront
4.0 star property
19.9 km from Mission District
8.6 out of 10, Excellent, (2780)
"Breakfast was very good, many options to choose. "
United States
Hourn
The price is ¥16,421
¥18,669 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Hilton San Francisco Airport Bayfront

King George Hotel

King George Hotel
3.0 star property
3.1 km from Mission District
8.6 out of 10, Excellent, (2101)
"Great place!"
United States
Troy
The price is ¥12,466
¥17,023 total
includes taxes & fees
Jan 4 - Jan 5, 2026
King George Hotel

Hotel Zoe Fisherman's Wharf

Hotel Zoe Fisherman's Wharf
4.0 star property
Fisherman's Wharf, 5.3 km from Mission District
9.2 out of 10, Wonderful, (1638)
"Great location, service, and rooms!"
United States
Joyce
The price is ¥18,178
¥28,050 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Hotel Zoe Fisherman's Wharf

Orchard Garden Hotel

Orchard Garden Hotel
4.0 star property
Chinatown, 3.7 km from Mission District
9.6 out of 10, Exceptional, (1007)
"Great location "
Canada
Jorge
The price is ¥18,589
¥22,233 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Orchard Garden Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Mission District

Find the best Mission District areas and neighborhoods for the activities you enjoy most. Learn more about Mission District
Learn more about Mission District

Union Square

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

Downtown San Francisco

Serving as San Francisco's central business district, this area boasts Northern California's two tallest buildings, the Salesforce Tower and Transamerica Pyramid. Explore shopping malls like the Embarcadero Center and enjoy parks such as Sue Biermann Park, all easily accessible via Muni bus and rail lines.

Fisherman's Wharf

Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.

South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

Nob Hill

Luxury hotels, historic mansions, and Michelin-starred restaurants abound in this upscale area. Explore Union Square shopping district, Grace Cathedral, and the SF Masonic Auditorium for a taste of culture and history.

Top Mission District Hotel Reviews

Find out more about Mission District

Top reasons to visit Mission District

  • Vibrant Street Art: Explore Balmy Alley and other areas adorned with stunning murals that reflect the rich culture of the Mission District.
  • Thriving Arts Scene: Discover local art galleries and participate in art walks that showcase the district's creativity.
  • Dynamic Nightlife: Experience energetic nightlife with a variety of nightclubs and bars to choose from.
  • Urban Parks: Enjoy outdoor activities in beautiful parks that blend urban life with nature.
  • Diverse Accommodations: Choose from a range of welcoming hotels that cater to different travelers' needs.

Find great hotels near Mission District

In the heart of San Francisco's vibrant Mission District, you'll discover a diverse selection of accommodations, including renowned hotel chains like Hilton. Expect welcoming environments tailored for business travelers and LGBTQIA guests alike, with convenient access to breakfast and accessible rooms. Whether you're looking for a comfortable stay or great shopping options, you'll find the perfect lodging through platforms like Agoda to enhance your visit.

  • Holiday Inn Golden Gateway by IHG: This 3.5-star hotel offers a modern business-themed experience for travelers seeking convenience and comfort. Located 3.2km from the vibrant Mission District, it features a central location ideal for exploring San Francisco. The hotel boasts extensive business amenities, including a 24-hour business center, multiple meeting rooms, and conference space, making it perfect for corporate travelers. Guests can unwind in well-appointed rooms, enjoy on-site dining, and take advantage of the fitness center. The Holiday Inn Golden Gateway is a great choice for those looking to balance work and leisure in the city.
  • The Westin St. Francis San Francisco on Union Square: This luxurious 4.5-star hotel combines a sophisticated city vibe with family-friendly amenities. Situated 3.2km from the Mission District, it is located in the heart of Union Square, perfect for shopping and entertainment. The Westin offers essential business facilities, including conference space and meeting rooms, while also catering to families with services like free cribs, babysitting options, and child safety features. Guests can enjoy elegant accommodations, renowned dining options, and a relaxing atmosphere that makes it an excellent choice for both business and leisure travelers.
  • Chancellor Hotel on Union Square: This charming 3.5-star hotel is perfect for shoppers and city explorers, situated 3.2km from Mission District in a bustling shopping district. The Chancellor Hotel’s prime location allows guests to easily access San Francisco’s iconic attractions. Known for its warm ambiance and personalized service, the hotel features cozy rooms and a welcoming atmosphere. Guests appreciate its central position, making it an ideal base for discovering the city’s rich culture and vibrant shopping scene. The Chancellor Hotel provides a delightful blend of convenience and comfort for any visitor.

Where to stay near Mission District

The Mission District is a vibrant neighborhood in San Francisco, perfect for families and city explorers alike. Here, you can wander through Balmy Alley, known for its stunning murals, and enjoy breathtaking city views from various lookout points. With a friendly atmosphere and plenty of outdoor spaces, you'll find a perfect blend of urban charm and scenic beauty while experiencing the local culture and cuisine.

  • San Francisco: San Francisco is a vibrant city known for its iconic landmarks, diverse culture, and stunning landscapes. Nestled along the Northern California coast, it offers a unique blend of urban charm and natural beauty. Visitors can enjoy a variety of experiences, from exploring the bustling Fisherman’s Wharf to taking a scenic walk across the Golden Gate Bridge. The Mission District itself is famous for its rich Latino heritage, colorful murals, and fantastic food scene, making it a must-visit for food lovers and art enthusiasts alike. Don’t miss the chance to stroll through the lush Golden Gate Park or catch a game at Oracle Park, home of the San Francisco Giants.
  • Union Square: Located just 3.2km from the Mission District, Union Square is the heart of San Francisco’s shopping and cultural scene. This vibrant neighborhood features an array of high-end retailers, boutique shops, and art galleries, attracting shoppers and sightseers alike. The square often hosts events, making it a lively gathering place for both locals and tourists. Nearby, you can catch a show at the historic Curran Theatre or enjoy a meal at one of the many acclaimed restaurants. Union Square is also conveniently located near public transportation, making it easy to explore the rest of the city.
  • Downtown San Francisco: Also situated 3.2km from the Mission District, Downtown San Francisco is a bustling business hub teeming with energy and activity. Here, you’ll find skyscrapers, tech startups, and a blend of modern and historic architecture. The neighborhood is a shopper's paradise, featuring everything from luxury boutiques to popular department stores, along with a vibrant dining scene. Highlights include the iconic Ferry Building Marketplace and the Embarcadero waterfront, where you can enjoy stunning views of the Bay Bridge. Downtown is also home to cultural attractions, including theaters and museums, ensuring there’s always something exciting happening.

Things to do in and around Mission District

The Mission District in San Francisco is perfect for family outings and urban adventures. Explore vibrant theaters, unique shopping areas, and lively malls. Don't miss the local art walks and the thriving arts community that showcase the district's creativity. For nightlife, check out the big nightclubs that add to the energetic atmosphere. With plenty of activities and attractions, the Mission District promises a memorable experience for every visitor.

Shopping

The shopping experience in the Mission District includes unique spots like Paxton Gate, where you can find eclectic gifts and souvenirs. For a bit of a drive, check out Ghirardelli Square for a variety of shops and a taste of San Francisco's charm. Don't miss Boudin Bakery for local treats.

Recreation

Enjoy an exhilarating day at Oracle Park, where you can soak in the vibrant sports atmosphere. For a dose of culture, head to the Bill Graham Civic Auditorium for captivating live performances. Finally, unwind at Presidio Golf Course, surrounded by stunning nature and scenic outdoor vibes.

Adventure

The Union Square Ice Rink offers a thrilling winter activity with ice skating amid vibrant city lights, located 3.2km away. For nature lovers, the Ecology Trail provides scenic hiking through beautiful landscapes, just 1.6km away. Perimeter Road invites outdoor enthusiasts for adventurous exploration, located 11.3km away.

Nightlife

The Mission District boasts a vibrant nightlife, with the Orpheum Theatre offering cultural performances and romantic evenings just 1.6km away. Nearby, the Castro Theatre adds to the entertainment scene with its charming cinema experience, while the Herschell-Spillman Carousel provides whimsical fun a couple of miles away.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Mission District

To save money during your visit to the Mission District, consider traveling in February or November to December, when accommodation prices are lower. Book your stay on a Friday for the best rates, as Tuesdays tend to be the most expensive. Utilize Expedia's search tool to find budget-friendly hotel options and consider package deals that combine flights and activities for additional savings. Take advantage of public transport, which is affordable and efficient, and look for beverage discounts at local establishments to stretch your budget further.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Mission District are February and November to December, where the prices are slightly lower. This is in comparison to August to October, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Mission District is Friday. The most expensive day to stay around Mission District is Tuesday.
  • Find cheap hotels on Expedia: Utilize Expedia’s search tool to narrow down your options based on your budget, desired location, and preferred hotel type. For the best prices and deals, be sure to arrange the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your hotel stay in the Mission District with your flights and activities through an Expedia package deal.

Find the best attractions near Mission District

The Mission District in San Francisco is perfect for family-friendly, urban adventures. Visitors can explore vibrant urban parks, art galleries, and colorful street murals that reflect the area's rich culture. With a variety of attractions catering to those seeking a blend of city life and family experiences, the Mission District offers an engaging vacation filled with artistic charm and outdoor fun.

  • Moscone Convention Center: Experience the dynamic atmosphere of this premier event venue, perfect for conferences and exhibitions. With its modern facilities and business-oriented environment, it's a hub for innovation and networking, drawing professionals from around the globe.
  • Union Square: Enjoy the vibrant energy of Union Square, a bustling urban plaza surrounded by shops, galleries, and cafes. This iconic square is the heart of San Francisco's shopping district, offering a lively city vibe that's perfect for people-watching and relaxation.
  • University of San Francisco: Explore the beautiful campus of this prestigious university, which blends stunning architecture with lush gardens. The university's urban setting provides a unique educational environment and a rich cultural experience, making it a great spot for a leisurely stroll.

Best time to go to Mission District

The best time to visit Mission District is dependant on what kind of holiday you are seeking. September is its hottest month on average. At this time, visitor numbers are average and weather is sunny with no rain. December is its coolest month on average. At this time, visitor numbers are slightly low and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January51.4°F (10.8°C)Light RainMostly SunnyAverageAverage
February52.2°F (11.2°C)Light RainMostly SunnyAverageSlightly Low
March53.4°F (11.9°C)Light RainMostly SunnySlightly HighAverage
April55.8°F (13.2°C)No RainMostly SunnySlightly HighAverage
May58.1°F (14.5°C)No RainSunnyAverageAverage
June62.1°F (16.7°C)No RainSunnyAverageAverage
July63.1°F (17.3°C)No RainSunnySlightly HighAverage
August64.2°F (17.9°C)No RainSunnyAverageSlightly High
September64.9°F (18.3°C)No RainSunnyAverageSlightly High
October62.6°F (17.0°C)No RainSunnySlightly LowSlightly High
November56.1°F (13.4°C)No RainMostly SunnySlightly LowSlightly Low
December51.3°F (10.7°C)Light RainMostly SunnySlightly LowSlightly Low

The nearest major airports for your trip to Mission District

Traveling to the Mission District in San Francisco is convenient with several major airports nearby. San Francisco International Airport (SFO) is situated 16.1km away, with luxurious hotel options like the Fairmont San Francisco and Palace Hotel, both offering transfers to the airport. Oakland International Airport (OAK) is 19.3km from the Mission District, featuring upscale accommodations such as 1 Hotel San Francisco and Claremont Resort & Club, which also provide easy access to the airport. Additionally, Norman Y. Mineta San Jose International Airport (SJC) is located 61.2km away, with elegant hotels like Shashi Hotel Mountain View Palo Alto offering nearby access.

Frequently asked questions

What is Mission District like?
Mission District is a neighborhood that travelers like for its bars. Are you looking for Mission District travel tips? Be sure to check out SOMA Pilipinas and Southern Exposure while you're in the neighborhood.
Where is the best place to stay in Mission District?
Based on Expedia customer reviews, Inn San Francisco is the highest ranked property in Mission District. This B&B offers free breakfast and a rooftop terrace. Other top choices in the neighborhood include Parker Guest House San Francisco and 1906 Mission.
How many hotels should I expect to find in the Mission District area?
Expedia has 75 hotels and other accommodations in Mission District to choose from, making this an ideal home base for exploring the greater San Francisco area.
If I need to cancel my hotel reservation in Mission District, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and receive a refund within a 24-hour period of booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to get top deals in Mission District.
Where can I learn more about changing or cancelling my trip to Mission District?
To access more information about rescheduling or cancelling your trip to Mission District, click here.
What are the top things to see and do in Mission District?
Mission District's sights and attractions like Marsh Theater, Victoria Theatre, and Creativity Explored offer insight into the local culture. SOMA Pilipinas and Southern Exposure are also a couple of places to visit in the neighborhood. Oracle Park, Paxton Gate, and Incline Gallery are just a few of the places to visit in and around Mission District. While you're out sightseeing in San Francisco, be sure to visit other sights like Mission Bowling Club or Clarion Alley.
How can I get around Mission District and the greater San Francisco area?
For a quick way to explore the city, catch a ride on metro transit at 16th Street Mission Station, 24th Street Mission Station, or Right Of Way/20th St Stop.

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