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Aug 22 - Aug 23
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Discover 363 Downtown Rochester hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Our top choices for Downtown Rochester hotels

Kahler Grand Hotel
Front of property - evening/night

Kahler Grand Hotel

3.0 star property
8.2 out of 10, Very Good, (1528)
"The location is excellent."
Kahler Grand Hotel
Hyatt House Rochester/Mayo Clinic Area
Terrace/patio

Hyatt House Rochester/Mayo Clinic Area

3.0 star property
9.2 out of 10, Wonderful, (999)
"Nice breakfast and soup"
The price is ￥19,135
￥22,030 total
includes taxes & fees
Aug 28 - Aug 29
Hyatt House Rochester/Mayo Clinic Area
Kahler Inn and Suites - Mayo Clinic Area
Room, 2 Queen Beds | Desk, blackout drapes, iron/ironing board, free cribs/infant beds

Kahler Inn and Suites - Mayo Clinic Area

3.5 star property
7.8 out of 10, Good, (1399)
"This hotel is very convenient It is very close to the Mayo! "
Kahler Inn and Suites - Mayo Clinic Area
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Property amenity

TownePlace Suites by Marriott Rochester Mayo Clinic Area

3.0 star property
9.6 out of 10, Exceptional, (447)
"Truly a great place to stay! "
The price is ￥15,426
￥17,759 total
includes taxes & fees
Aug 29 - Aug 30
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Brentwood Inn & Suites
Desk, iron/ironing board, free WiFi, bed sheets

Brentwood Inn & Suites

2.5 star property
8.6 out of 10, Excellent, (1004)
"I enjoyed my stay. Room was clean and the staff was helpful and friendly."
The price is ￥16,687
￥19,210 total
includes taxes & fees
Aug 24 - Aug 25
Brentwood Inn & Suites
Marriott Rochester Mayo Clinic
View from property

Marriott Rochester Mayo Clinic

3.5 star property
8.2 out of 10, Very Good, (514)
"When we walked back to the hotel from a restaurant across the street, there was the smell of urine and a puddle of urine where the cars drive up to the entrance of the hotel"
The price is ￥31,001
￥35,691 total
includes taxes & fees
Sep 12 - Sep 13
Marriott Rochester Mayo Clinic
The Towers At Kahler Grand Hotel
Front of property

The Towers At Kahler Grand Hotel

4.0 star property
9.4 out of 10, Exceptional, (87)
"Great location next to Mayo Clinic."
The price is ￥52,686
￥60,655 total
includes taxes & fees
Aug 24 - Aug 25
The Towers At Kahler Grand Hotel
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Exterior

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 star property
8.8 out of 10, Excellent, (813)
"Great place, staff was friendly. Beds were comfortable. Would stay again. "
The price is ￥11,421
￥13,594 total
includes taxes & fees
Sep 12 - Sep 13
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Hilton Rochester Mayo Clinic Area
Lobby

Hilton Rochester Mayo Clinic Area

3.5 star property
9.6 out of 10, Exceptional, (508)
"Very close to Mayo and numerous restaurants."
The price is ￥26,351
￥30,336 total
includes taxes & fees
Aug 30 - Aug 31
Hilton Rochester Mayo Clinic Area
Hilton Garden Inn Rochester Downtown, MN
Breakfast served

Hilton Garden Inn Rochester Downtown, MN

3.0 star property
8.8 out of 10, Excellent, (801)
"Very good location "
The price is ￥17,525
￥20,176 total
includes taxes & fees
Aug 29 - Aug 30
Hilton Garden Inn Rochester Downtown, MN
Broadway Plaza, Trademark Collection by Wyndham
Fridge, microwave, oven, stovetop

Broadway Plaza, Trademark Collection by Wyndham

3.0 star property
9.2 out of 10, Wonderful, (159)
"Very close to Mayo"
The price is ￥23,672
￥27,254 total
includes taxes & fees
Aug 29 - Aug 30
Broadway Plaza, Trademark Collection by Wyndham
Residence Inn by Marriott Rochester Mayo Clinic Area
Terrace/patio

Residence Inn by Marriott Rochester Mayo Clinic Area

3.0 star property
8.4 out of 10, Very Good, (198)
"Hotel is being renovated. Great location, nice room, good breakfast and service. "
The price is ￥29,518
￥33,983 total
includes taxes & fees
Aug 24 - Aug 25
Residence Inn by Marriott Rochester Mayo Clinic Area
Econo Lodge Mayo Clinic Area
Free daily full breakfast

Econo Lodge Mayo Clinic Area

2.0 star property
9.0 out of 10, Wonderful, (769)
"Good clean older hotel."
The price is ￥9,330
￥10,742 total
includes taxes & fees
Sep 7 - Sep 8
Econo Lodge Mayo Clinic Area
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Front of property

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

3.0 star property
7.2 out of 10, Good, (1002)
"Loved the kid area in the pool"
The price is ￥10,679
￥12,295 total
includes taxes & fees
Aug 24 - Aug 25
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Aspen Suites
Exterior

Aspen Suites

3.0 star property
9.0 out of 10, Wonderful, (642)
"Convenient and nice hotel. "
Aspen Suites
AmericInn by Wyndham Rochester Near Mayo Clinic
Serves lunch, dinner, and happy hour

AmericInn by Wyndham Rochester Near Mayo Clinic

3.0 star property
8.0 out of 10, Very Good, (988)
"It was in a good location near the downtown."
The price is ￥11,085
￥12,761 total
includes taxes & fees
Sep 23 - Sep 24
AmericInn by Wyndham Rochester Near Mayo Clinic
EVEN Hotel Rochester - Mayo Clinic Area by IHG
Courtyard

EVEN Hotel Rochester - Mayo Clinic Area by IHG

4.0 star property
9.4 out of 10, Exceptional, (874)
"Excellent and very clean property, beds were amazing "
The price is ￥17,651
￥20,618 total
includes taxes & fees
Aug 31 - Sep 1
EVEN Hotel Rochester - Mayo Clinic Area by IHG
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
In-room safe, desk, iron/ironing board, free cribs/infant beds

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

2.0 star property
8.0 out of 10, Very Good, (1002)
"I liked the quietness, cleanliness, and the breakfasts. The bus stop is ever so close. I was happy to see Mayo Clinic is within walking distance.l enjoyed my stay."
The price is ￥9,836
￥11,323 total
includes taxes & fees
Sep 5 - Sep 6
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room) | 1 bedroom, blackout drapes, soundproofing, iron/ironing board

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

2.5 star property
8.2 out of 10, Very Good, (702)
"Nice place to stay"
The price is ￥12,541
￥14,437 total
includes taxes & fees
Aug 26 - Aug 27
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Aspen Select
Exterior

Aspen Select

3.5 star property
8.4 out of 10, Very Good, (1001)
"great receptionist ! "
Aspen Select
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Downtown Rochester

Find the best Downtown Rochester areas and neighborhoods for the activities you enjoy most.

Kutzky Park

While there might not be top attractions in Kutzky Park, you can explore the larger area and discover places like Soldiers Field Veterans Memorial and Mayo Civic Center.

Rochester featuring forest scenes and a river or creek
Photo by Chad Johnson
Open Photo by Chad Johnson

Historic Southwest

While visiting Historic Southwest, you might make a stop by sights like Soldiers Field Veterans Memorial and Plummer House.

East Side Pioneers

If you're spending some time in East Side Pioneers, Rochester Art Center and Mayo Civic Center are top sights worth seeing.

Slatterly Park

Slatterly Park might not have many top sights, but Rochester Art Center and Soldiers Field Veterans Memorial are two attractions nearby that you can check out.

Northrup

Though Northrup might not have many top sights, you can venture to the surrounding area to see attractions like Mayo Civic Center and Rochester Art Center.

Top Downtown Rochester Hotel Reviews

AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

10/10 Excellent
"Great stay"
Kevin 1-night trip
Posted 10 hours ago
AmericInn by Wyndham Rochester Near Mayo Clinic

Frequently asked questions

What's it like in Downtown Rochester?

You'll be sure to have fun visiting Rochester's Downtown Rochester neighborhood. Are you looking for Downtown Rochester travel tips? Be sure to check out Mayo Civic Center and Rochester Art Center while you're in the neighborhood.

What's a favorite place to stay in Downtown Rochester?

Based on Expedia customer reviews, TownePlace Suites by Marriott Rochester Mayo Clinic Area is the highest ranked property in Downtown Rochester. This hotel is a short 5-minute walk from Mayo Clinic, and it offers free breakfast and a 24-hour fitness center. Other favorite options in the area include Hilton Rochester Mayo Clinic Area and The Towers At Kahler Grand Hotel.

How many hotels will I be able to find in the Downtown Rochester area?

If you're searching for places to stay in Rochester, choose from one of Expedia's 19 hotels and other accommodations in Downtown Rochester.

If I need to cancel my hotel reservation in Downtown Rochester, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to view the top deals on offer in Downtown Rochester.

Where can I learn more about changing or cancelling my trip to Downtown Rochester?

For additional details about rescheduling or cancelling your trip to Downtown Rochester, click here.

What is there to do in this Rochester neighborhood?

Mayo Civic Center, Rochester Art Center, and Shops University Square are just a few attractions to check out in Downtown Rochester. Rochester Civic Theater and Plummer Building are also a couple of places to visit in the neighborhood. A few places to visit in the area around Downtown Rochester include Rochester Public Library, Soldiers Field Veterans Memorial, and Soldiers Field Golf Course. Kutzky Park Tennis Center and Plummer House are also worth a visit when you're out sightseeing in Rochester.