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Our top choices for Downtown Rochester hotels

Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area
3.5 star property
Downtown Rochester
9.6 out of 10, Exceptional, (599 reviews)
"This hotel was beautiful and spotless! Staff was friendly. Even the option to order Benedicts directly to your room! Will definitely choose to stay here again!"
United States
Marcie
The price is ¥28,507
¥32,819 total
includes taxes & fees
Jun 12 - Jun 13
Hilton Rochester Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area
3.0 star property
Downtown Rochester
9.0 out of 10, Wonderful, (1,000 reviews)
"Great stay for my daughters volleyball weekend! "
United States
Lori
The price is ¥22,065
¥25,402 total
includes taxes & fees
May 31 - Jun 1
Hyatt House Rochester/Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area
3.5 star property
Downtown Rochester
8.0 out of 10, Very Good, (1,568 reviews)
"Staff are very friendly and helpful"
United States
Shelby
The price is ¥20,668
¥23,794 total
includes taxes & fees
May 18 - May 19
Kahler Inn and Suites - Mayo Clinic Area

The Towers At Kahler Grand Hotel

The Towers At Kahler Grand Hotel
4.0 star property
Downtown Rochester
9.4 out of 10, Exceptional, (101 reviews)
"Excellent accommodations, amazing staff"
United States
Shannon
The price is ¥55,103
¥63,438 total
includes taxes & fees
May 22 - May 23
The Towers At Kahler Grand Hotel

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 star property
Downtown Rochester
8.8 out of 10, Excellent, (1,000 reviews)
"Clean, comfortable hotel in a great location. It’s surrounded by bars and restaurants. The parking garage attached to the hotel is not included in the nightly price but when we were there, it was only $16 for the night, not bad."
United States
Veronica
The price is ¥14,763
¥16,996 total
includes taxes & fees
May 24 - May 25
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN
3.0 star property
Downtown Rochester
8.8 out of 10, Excellent, (904 reviews)
"Nice hotel near mayo. "
United States
Rob
The price is ¥19,395
¥22,329 total
includes taxes & fees
May 25 - May 26
Hilton Garden Inn Rochester Downtown, MN

Kahler Grand Hotel

Kahler Grand Hotel
3.0 star property
Downtown Rochester
8.4 out of 10, Very Good, (2,088 reviews)
"Beautiful, well maintained hotel very convenient to Mayo Clinic offices."
United States
Jeffrey
The price is ¥19,868
¥22,873 total
includes taxes & fees
May 21 - May 22
Kahler Grand Hotel

Marriott Rochester Mayo Clinic

Marriott Rochester Mayo Clinic
3.5 star property
Downtown Rochester
8.4 out of 10, Very Good, (552 reviews)
"Rooms were very nice and the front staff was very helpful "
United States
Shawna
The price is ¥30,002
¥34,540 total
includes taxes & fees
May 22 - May 23
Marriott Rochester Mayo Clinic

Brentwood Inn & Suites

Brentwood Inn & Suites
2.5 star property
Downtown Rochester
8.8 out of 10, Excellent, (1,003 reviews)
"Very good and well stocked breakfast , good parking staff was helpful and friendly "
United States
Brian
The price is ¥17,858
¥20,558 total
includes taxes & fees
May 24 - May 25
Brentwood Inn & Suites

Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham
3.0 star property
Downtown Rochester
9.2 out of 10, Wonderful, (177 reviews)
"As always excellent staff, clean and comfortable rooms. Great central location. "
Canada
Anita
The price is ¥24,152
¥27,804 total
includes taxes & fees
May 31 - Jun 1
Broadway Plaza, Trademark Collection by Wyndham

Residence Inn by Marriott Rochester Mayo Clinic Area

Residence Inn by Marriott Rochester Mayo Clinic Area
3.0 star property
Downtown Rochester
8.4 out of 10, Very Good, (208 reviews)
"Dan, the manager was so friendly and accommodating! "
United States
Brittany
The price is ¥26,827
¥30,886 total
includes taxes & fees
May 23 - May 24
Residence Inn by Marriott Rochester Mayo Clinic Area

Comfort Inn & Suites Rochester South Mayo Clinic

Comfort Inn & Suites Rochester South Mayo Clinic
2.0 star property
11.8 km from Downtown Rochester
8.8 out of 10, Excellent, (1,006 reviews)
"Breakfast was good"
United States
Thomas
The price is ¥10,429
¥12,007 total
includes taxes & fees
May 31 - Jun 1
Comfort Inn & Suites Rochester South Mayo Clinic

America's Stay Inn Stewartville

America's Stay Inn Stewartville
2.5 star property
17.2 km from Downtown Rochester
8.0 out of 10, Very Good, (442 reviews)
"Very nice clean rooms with plenty of parking. Will stay here again when traveling in the future."
United States
Debbie
The price is ¥9,570
¥10,276 total
includes taxes & fees
May 18 - May 19
America's Stay Inn Stewartville

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3.0 star property
6.9 km from Downtown Rochester
7.4 out of 10, Good, (1,064 reviews)
"clean room and whole building,very quite"
United States
Gunnar
The price is ¥11,975
¥13,786 total
includes taxes & fees
Jun 10 - Jun 11
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

Hampton Inn Rochester-South

Hampton Inn Rochester-South
2.5 star property
2.9 km from Downtown Rochester
9.0 out of 10, Wonderful, (1,005 reviews)
"Everything with the room and staff was great."
United States
Susan R
The price is ¥16,097
¥18,531 total
includes taxes & fees
Jun 16 - Jun 17
Hampton Inn Rochester-South

Holiday Inn Express Rochester South - Mayo Area by IHG

Holiday Inn Express Rochester South - Mayo Area by IHG
2.5 star property
6.7 km from Downtown Rochester
8.8 out of 10, Excellent, (1,001 reviews)
"We enjoyed a nice quiet stay with great breakfast. "
United States
Joyce
The price is ¥14,604
¥16,812 total
includes taxes & fees
May 24 - May 25
Holiday Inn Express Rochester South - Mayo Area by IHG

Residence Inn by Marriott Rochester Mayo Clinic Area South

Residence Inn by Marriott Rochester Mayo Clinic Area South
3.0 star property
2.5 km from Downtown Rochester
9.6 out of 10, Exceptional, (283 reviews)
"Great stay."
United States
Engen
The price is ¥20,954
¥24,124 total
includes taxes & fees
May 22 - May 23
Residence Inn by Marriott Rochester Mayo Clinic Area South

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 star property
2.9 km from Downtown Rochester
8.2 out of 10, Very Good, (917 reviews)
"Great pool area, decent breakfast."
United States
Jessica
The price is ¥14,929
¥17,186 total
includes taxes & fees
Jun 4 - Jun 5
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Spark by Hilton Rochester South

Spark by Hilton Rochester South
3.0 star property
6.8 km from Downtown Rochester
9.4 out of 10, Exceptional, (473 reviews)
"Comfortable beds, and friendly staff."
United States
Desyre
The price is ¥12,683
¥14,601 total
includes taxes & fees
Jun 7 - Jun 8
Spark by Hilton Rochester South

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
2.0 star property
5.8 km from Downtown Rochester
8.0 out of 10, Very Good, (1,000 reviews)
"Clean room, excellent customer service. "
United States
Olubodun
The price is ¥11,064
¥12,738 total
includes taxes & fees
May 19 - May 20
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Downtown Rochester

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Presidential Suite, Multiple Beds | Living area | 55-inch LCD TV with satellite channels, TV
Hilton Rochester Mayo Clinic Area
3.5 star property
9.6
Exceptional
599 reviews
View
Front of property - evening/night
The Towers At Kahler Grand Hotel
4.0 star property
9.4
Exceptional
101 reviews
View
Two-Bedroom Apartment - Mobility Accessible/Non-Smoking | In-room safe, individually furnished, desk, laptop workspace
Broadway Plaza, Trademark Collection by Wyndham
3.0 star property
9.2
Wonderful
177 reviews
View
Terrace/patio
Hyatt House Rochester/Mayo Clinic Area
3.0 star property
9.0
Wonderful
1,000 reviews
View
Lobby sitting area
Brentwood Inn & Suites
2.5 star property
8.8
Excellent
1,003 reviews
View

Where to stay in Downtown Rochester

Find the best Downtown Rochester areas and neighborhoods for the activities you enjoy most.

Kutzky Park

While there might not be top attractions in Kutzky Park, you can explore the larger area and discover places like Soldiers Field Veterans Memorial and Mayo Civic Center.

Historic Southwest

While visiting Historic Southwest, you might make a stop by sights like Soldiers Field Veterans Memorial and Plummer House.

Slatterly Park

Slatterly Park might not have many top sights, but Soldiers Field Golf Course and Rochester Art Center are two attractions nearby that you can check out.

East Side Pioneers

If you're spending some time in East Side Pioneers, Rochester Art Center and Mayo Civic Center are top sights worth seeing.

Northrup

Though Northrup might not have many top sights, you can venture to the surrounding area to see attractions like Mayo Civic Center and Rochester Art Center.

Top Downtown Rochester Hotel Reviews

Frequently asked questions

What's it like in Downtown Rochester?
You'll be sure to have fun visiting Rochester's Downtown Rochester neighborhood. Are you looking for Downtown Rochester travel tips? Be sure to check out Mayo Civic Center and Rochester Art Center while you're in the neighborhood.
What's a favorite place to stay in Downtown Rochester?
Based on our traveler data, Kahler Grand Hotel is one of the top choices for your stay in Downtown Rochester. This hotel is a short 4-minute walk from Mayo Clinic, and it offers 2 restaurants and an indoor pool. Other good options for your stay in the area include Kahler Inn and Suites - Mayo Clinic Area and Hyatt House Rochester/Mayo Clinic Area.
How many hotels will I be able to find in the Downtown Rochester area?
Expedia has 20 hotels and other accommodations in Downtown Rochester to choose from, making this an ideal home base for exploring the greater Rochester area.
If I need to cancel my hotel reservation in Downtown Rochester, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to view the top deals on offer in Downtown Rochester.
Where can I learn more about changing or cancelling my trip to Downtown Rochester?
For additional details about rescheduling or cancelling your trip to Downtown Rochester, click here.
What is there to do in this Rochester neighborhood?
Mayo Civic Center, Rochester Art Center, and Rochester Civic Theater are just a few attractions to check out in Downtown Rochester. Plummer Building and Shops University Square are also a couple of places to visit in the neighborhood. A few places to visit in the area around Downtown Rochester include Rochester Public Library, Soldiers Field Veterans Memorial, and Soldiers Field Golf Course. Kutzky Park Tennis Center and Plummer House are also worth a visit when you're out sightseeing in Rochester.

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