Find Business Hotels in Central San Diego, CA
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Our top choices for Central San Diego business-friendly hotels
DoubleTree by Hilton Hotel San Diego - Mission Valley
DoubleTree by Hilton Hotel San Diego - Mission ValleyMission Valley
8.4 out of 10, Very Good, (1440)
"The room was super quiet and clean. The staff was kind at check in and check out. We would definitely stay here again. "
Janelle
The price is ￥17,522
￥20,140 total
includes taxes & fees
Jan 3 - Jan 4, 2026
8.8 out of 10, Excellent, (1332)
"Checking in was easy and friendly staff."
Elvira
The price is ￥14,370
￥16,518 total
includes taxes & fees
Jan 25 - Jan 26, 2026
Courtyard by Marriott San Diego Mission Valley/Hotel Circle
Courtyard by Marriott San Diego Mission Valley/Hotel CircleMission Valley
8.4 out of 10, Very Good, (1447)
"Staff was very friendly, everything was very clean. "
Cristine
The price is ￥14,848
￥17,066 total
includes taxes & fees
Jan 4 - Jan 5, 2026
9.2 out of 10, Wonderful, (2946)
"Great boutique hotel!!"
Maksim
Best Western Plus Hacienda Hotel Old Town
Best Western Plus Hacienda Hotel Old TownOld Town San Diego
8.4 out of 10, Very Good, (1875)
"Great location, friendly staff, clean room. "
Marleny
The price is ￥18,110
￥20,817 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hilton Garden Inn San Diego Mission Valley Stadium
Hilton Garden Inn San Diego Mission Valley StadiumKearny Mesa
8.0 out of 10, Very Good, (1005)
"Great staff and room was nice and clean. My family and I will definitely be back. "
Bo
The price is ￥16,564
￥19,039 total
includes taxes & fees
Jan 11 - Jan 12, 2026
8.2 out of 10, Very Good, (2260)
"Room and staff were excellent"
Bryant
7.2 out of 10, Good, (1079)
"Another great stay 😇👍"
Dan
The price is ￥11,932
￥13,454 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Central San Diego Hotel Reviews
DoubleTree by Hilton San Diego - Hotel Circle
10/10 Excellent
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