A red train on tracks, palm trees, and modern buildings.

Central San Diego Vacation Rentals

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Check prices for these dates

In two weeks
Oct 16 - Oct 18
In two months
Nov 27 - Nov 29
In three months
Dec 25 - Dec 27
In four months
Jan 22 - Jan 24

Our top choices for Central San Diego vacation rentals

A narrow, enclosed walkway with wooden railings and a metal grid barrier, leading to a building entrance.

1. City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.6 out of 10, Exceptional, (217 reviews)
"Top stay when we go out with our friends !"
United States
Jesus
The price is ￥18,246
￥25,926 total
includes taxes & fees
Oct 26 - Oct 27
City24 Hotel Little Italy Mission Hills
A spacious lobby with a sofa, chairs, a bookshelf, and a large window with a view of greenery.

2. Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Uptown Inn by Vantaggio - Limited Service Apart-Hotel
2.5 star property
Hillcrest
8.4 out of 10, Very good, (477 reviews)
"It's good hotel for small day 1 to 3 nights no more then that due to the size of the room."
Canada
patrick
The price is ￥14,719
￥16,596 total
includes taxes & fees
Oct 5 - Oct 6
Uptown Inn by Vantaggio - Limited Service Apart-Hotel
A bedroom with a bed, a desk, a chair, a ceiling fan, and a door leading to another room.

3. Private Entrance With Crisp Sheets And A Cozy Grotto Shower

Private Entrance With Crisp Sheets And A Cozy Grotto Shower
Mid-City
10.0 out of 10, Exceptional, (1 review)
"Simple property that does the job! Pleasant experience!"
United States
Brandon S.
The price is ￥9,918
￥22,319 total
includes taxes & fees
Oct 13 - Oct 14
Private Entrance With Crisp Sheets And A Cozy Grotto Shower
A two-story house with a prominent front entrance, a balcony, and a garage.

4. San Diego Centralized Retreat

San Diego Centralized Retreat
Birdland
10.0 out of 10, Exceptional, (1 review)
"A beautiful apartment! Definitely going to reserve that location for more days next time. Kitchen is great and loved having upstairs-downstairs for separate spaces when one of us was working"
United States
Margaret C.
The price is ￥10,976
￥31,322 total
includes taxes & fees
Oct 14 - Oct 15
San Diego Centralized Retreat
A living room with a blue sofa, a round coffee table, and a world map on the wall.

5. Charming 2 bedroom San Diego home-Close to Downtown/Balboa Park/SeaWorld/Beaches

Charming 2 bedroom San Diego home-Close to Downtown/Balboa Park/SeaWorld/Beaches
Mid-City
8.0 out of 10, Very good, (4 reviews)
"We thoroughly appreciated the communications provided by the host. Initially had a few teething issues, with the keylock code not working, and a smell in the bedroom and the living area, but this was rectified and a cleaning crew came in twice for it. Place is perfectly situated (with car use) but a bit less so if on foot, or public transportation. The laundry in the shed and the kitchen are always welcome especially as our booking was over 2 weeks long! Thanks again for a suitable stay for us!"
United States
Carlo Luis
The price is ￥16,832
￥71,618 total
includes taxes & fees
Oct 12 - Oct 13
Charming 2 bedroom San Diego home-Close to Downtown/Balboa Park/SeaWorld/Beaches
A modern living room with a green sofa, a round coffee table, and a dining area with a table and chairs.

6. 1BR King Bed Apartment with AC in sunny San Diego

1BR King Bed Apartment with AC in sunny San Diego
Mid-City
The price is ￥14,877
￥42,010 total
includes taxes & fees
Oct 4 - Oct 5
1BR King Bed Apartment with AC in sunny San Diego
A patio with outdoor furniture, a pathway, and a fence.

7. Cozy 2-Bedroom Cottage Near Balboa Park

Cozy 2-Bedroom Cottage Near Balboa Park
Mid-City
8.8 out of 10, Excellent, (12 reviews)
"Overall it was a great place to stay."
United States
Cristal M.
The price is ￥20,308
￥47,303 total
includes taxes & fees
Oct 4 - Oct 5
Cozy 2-Bedroom Cottage Near Balboa Park
A hotel room with two beds, a large mirror, and decorative wall art.

8. Modern 1BR/1BA Getaway in Central San Diego – Walk to Zoo, Balboa Park & Dining

Modern 1BR/1BA Getaway in Central San Diego – Walk to Zoo, Balboa Park & Dining
University City
10.0 out of 10, Exceptional, (1 review)
"Nice spacious 1 bed room apartment in very nice area "
United States
ILL W.
The price is ￥28,337
￥49,886 total
includes taxes & fees
Oct 13 - Oct 14
Modern 1BR/1BA Getaway in Central San Diego – Walk to Zoo, Balboa Park & Dining
A modern living room with a grey sofa, a small round coffee table, and a ceiling fan.

9. Charming 1-bedroom house in Beautiful San Diego with WiFi, AC

Charming 1-bedroom house in Beautiful San Diego with WiFi, AC
Mid-City
10.0 out of 10, Exceptional, (2 reviews)
"Our stay was excellent. We enjoyed the space. Used TV, sofa and bed… nothing else. Quiet and easy access to property. "
United States
Socorro C.
The price is ￥22,040
￥47,481 total
includes taxes & fees
Oct 5 - Oct 6
Charming 1-bedroom house in Beautiful San Diego with WiFi, AC
A modern kitchen with white cabinetry, a built-in microwave, a dishwasher, and a stainless steel refrigerator.

10. Luxury San Diego 1BR with Premium Conveniences

Luxury San Diego 1BR with Premium Conveniences
Mid-City
The price is ￥18,419
￥44,858 total
includes taxes & fees
Oct 12 - Oct 13
Luxury San Diego 1BR with Premium Conveniences
A living room with a green sofa, a coffee table, and a dining area with a table and chairs. There are plants and framed pictures on the walls.

11. Colorful & Cozy Oasis: Walk Score 95/100, Free Pkg

Colorful & Cozy Oasis: Walk Score 95/100, Free Pkg
North Park
9.6 out of 10, Exceptional, (9 reviews)
"Very kind host and great walkable location. The yard made it very convenient for my dog and the bed was super comfy"
United States
Rae-Matthew E.
The price is ￥16,832
￥50,679 total
includes taxes & fees
Oct 4 - Oct 5
Colorful & Cozy Oasis: Walk Score 95/100, Free Pkg
A modern living room with a dark wood floor, a black leather sofa, a dining table with chairs, and a large potted plant.

12. Charming 2-bedroom apartment in terrific San Diego North Park Area with WiFi

Charming 2-bedroom apartment in terrific San Diego North Park Area with WiFi
North Park
7.4 out of 10, Good, (6 reviews)
"We left something at the home & host contacted us to figure it out."
United States
Blake G.
The price is ￥18,892
￥44,504 total
includes taxes & fees
Oct 4 - Oct 5
Charming 2-bedroom apartment in terrific San Diego North Park Area with WiFi
A balcony with a fire feature, a grill, and a view of a cityscape at sunset.

13. Close to Airport | Walk to Restaurants

Close to Airport | Walk to Restaurants
Middletown
8.8 out of 10, Excellent, (3 reviews)
"Exactly as advertised. Door to bathroom being shutters was an interesting decision but apart from that it was clean and in good condition and generally a good place to stay. Great location, close to a row of restaurants and can see the taxiways for San Diego international."
United States
Yan W.
The price is ￥13,854
￥52,764 total
includes taxes & fees
Oct 14 - Oct 15
Close to Airport | Walk to Restaurants
A building with a covered outdoor seating area, surrounded by various plants and a large rock.

14. Adorable 1 bd cottage, heart of Old Town-- WE LOVE PETS! Insta @oldtownvacay

Adorable 1 bd cottage, heart of Old Town-- WE LOVE PETS! Insta @oldtownvacay
Old Town San Diego
10.0 out of 10, Exceptional, (304 reviews)
"Super cute, private little cottage in a great location. Loved the stay, very easy process and great host!"
United States
Ross
The price is ￥24,795
￥31,577 total
includes taxes & fees
Oct 5 - Oct 6
Adorable 1 bd cottage, heart of Old Town-- WE LOVE PETS! Insta @oldtownvacay
A bedroom with a bed, a TV, a ceiling fan, and a view of a living room with a blue sofa.

15. Stylish & Comfy Gem: Walk To Everything ~ Parking!

Stylish & Comfy Gem: Walk To Everything ~ Parking!
North Park
9.0 out of 10, Wonderful, (2 reviews)
"Great stay, very tight parking spot though!"
United States
Alana M.
The price is ￥16,832
￥50,679 total
includes taxes & fees
Oct 4 - Oct 5
Stylish & Comfy Gem: Walk To Everything ~ Parking!
A beach with waves and a sunset.

16. The Great Escape 1| Free Beach Gear | Hot Tub, Harbor Views & Fire Pit

The Great Escape 1| Free Beach Gear | Hot Tub, Harbor Views & Fire Pit
Middletown
8.4 out of 10, Very good, (5 reviews)
"The stay was wonderful, location was great, view was nice. Backyard was wonderful, had so much fun playing all of the games. Inside was a little small in the bedrooms but living room was spacious. But surprisingly….the best part was the bidet! We all were shocked with how nice it was as to have, will definitely be getting one of those going home!"
United States
Andrea W.
The price is ￥20,608
￥60,261 total
includes taxes & fees
Oct 20 - Oct 21
The Great Escape 1| Free Beach Gear | Hot Tub, Harbor Views & Fire Pit
A sunset over a beach with a pier in the background.

17. Adorable 1 bedroom house 8 min from La Jolla!

Adorable 1 bedroom house 8 min from La Jolla!
Bay Ho
10.0 out of 10, Exceptional, (62 reviews)
"Clean place, great location, great AC, can’t ask for more! Perfect for a couple."
United States
Justin H.
The price is ￥29,754
￥49,551 total
includes taxes & fees
Oct 14 - Oct 15
Adorable 1 bedroom house 8 min from La Jolla!
A modern living room with a grey sofa, a wooden coffee table, and a dining area with a small table and chairs.

18. Relaxing Retreat in North Park – 3943

Relaxing Retreat in North Park – 3943
North Park
8.0 out of 10, Very good, (3 reviews)
"Host is very responsive which I always appreciate. The place is very practical and the location is great."
United States
Andrea S.
The price is ￥14,962
￥40,807 total
includes taxes & fees
Oct 20 - Oct 21
Relaxing Retreat in North Park – 3943
An outdoor patio area with seating, potted plants, and string lights.

19. Chic Brand-New Penthouse overlooking North Park

Chic Brand-New Penthouse overlooking North Park
North Park
9.8 out of 10, Exceptional, (30 reviews)
"Location is excellent very safe parking garage and secure parkingPlace was very cozy and clean with all the basics provided will definitely come back again"
United States
Spomenka S.
The price is ￥21,725
￥59,514 total
includes taxes & fees
Oct 5 - Oct 6
Chic Brand-New Penthouse overlooking North Park
A beachside hotel with multiple floors, a sandy beach in the foreground, and palm trees lining the shore.

20. Secluded, Charming and Unique! Spacious Apartment EXCELLENT Central Location

Secluded, Charming and Unique! Spacious Apartment EXCELLENT Central Location
Mission Valley
9.0 out of 10, Wonderful, (67 reviews)
"It was okay"
United States
Nicole
The price is ￥21,253
￥53,221 total
includes taxes & fees
Oct 6 - Oct 7
Secluded, Charming and Unique! Spacious Apartment EXCELLENT Central Location
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Central San Diego Hotel Reviews

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

10/10 Excellent
"Every thing was perfect clean staff breakfast bar and the location closed to every place with car"
Tamara 3-night trip
Posted less than an hour ago
Legacy Resort Hotel & Spa

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