Find hotels in Byron, MN from ￥9,901

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
May 29 - May 31
Next weekend
Jun 5 - Jun 7

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Byron hotels

Lobby

Americas Best Value Inn & Suites Spring Valley

Americas Best Value Inn & Suites Spring Valley
2.0 star property
Spring Valley
8.2 out of 10, Very Good, (447 reviews)
"Staff was helpful and attentive. Breakfast had more options than other lodgings on our trip in same price range. Lay out was convenient for loading in/out and amenities. Would definitely stay here again."
United States
Jenifer
The price is ￥12,582
￥13,887 total
includes taxes & fees
May 28 - May 29
Americas Best Value Inn & Suites Spring Valley
Reception

America's Stay Inn Stewartville

America's Stay Inn Stewartville
2.5 star property
Stewartville
8.0 out of 10, Very Good, (444 reviews)
"Very nice clean rooms with plenty of parking. Will stay here again when traveling in the future."
United States
Debbie
The price is ￥10,032
￥10,772 total
includes taxes & fees
May 28 - May 29
America's Stay Inn Stewartville
Lobby

Comfort Inn & Suites Rochester South Mayo Clinic

Comfort Inn & Suites Rochester South Mayo Clinic
2.0 star property
Rochester
8.8 out of 10, Excellent, (1,005 reviews)
"Breakfast was good"
United States
Thomas
The price is ￥11,976
￥13,788 total
includes taxes & fees
Jun 7 - Jun 8
Comfort Inn & Suites Rochester South Mayo Clinic
Reception

Spark by Hilton Rochester South

Spark by Hilton Rochester South
3.0 star property
Rochester
9.4 out of 10, Exceptional, (485 reviews)
"Comfortable beds, and friendly staff."
United States
Desyre
The price is ￥12,724
￥14,649 total
includes taxes & fees
Jun 14 - Jun 15
Spark by Hilton Rochester South
Front of property

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3.0 star property
Rochester
7.4 out of 10, Good, (1,059 reviews)
"Very clean room. For the price this motel was an excellent stay. Great location. "
United States
Lorrie
The price is ￥11,952
￥13,760 total
includes taxes & fees
Jun 14 - Jun 15
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Restaurant

Hampton Inn & Suites Rochester-North

Hampton Inn & Suites Rochester-North
2.5 star property
Rochester
9.2 out of 10, Wonderful, (1,000 reviews)
"Our favorite is the hotels shuttle service to Mayo"
United States
Laureen
The price is ￥17,630
￥20,298 total
includes taxes & fees
Jun 4 - Jun 5
Hampton Inn & Suites Rochester-North
Exterior

Holiday Inn Express Rochester South - Mayo Area by IHG

Holiday Inn Express Rochester South - Mayo Area by IHG
2.5 star property
Rochester
8.8 out of 10, Excellent, (1,000 reviews)
"We enjoyed a nice quiet stay with great breakfast. "
United States
Joyce
The price is ￥15,289
￥17,601 total
includes taxes & fees
Jun 7 - Jun 8
Holiday Inn Express Rochester South - Mayo Area by IHG
Serves lunch, dinner, and happy hour

AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic
3.0 star property
Rochester
8.0 out of 10, Very Good, (1,338 reviews)
"Good breakfast, good value, and a restaurant on site."
United States
Timothy
The price is ￥12,454
￥14,337 total
includes taxes & fees
Jun 14 - Jun 15
AmericInn by Wyndham Rochester Near Mayo Clinic
Indoor pool, open 9:00 AM to 10:00 PM, pool umbrellas, sun loungers

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 star property
Rochester
8.2 out of 10, Very Good, (926 reviews)
"Great pool area, decent breakfast."
United States
Jessica
The price is ￥14,978
￥17,242 total
includes taxes & fees
Jun 18 - Jun 19
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Free daily full breakfast

Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
2.0 star property
Rochester
9.0 out of 10, Wonderful, (986 reviews)
"My stay was short and sweet so it was very comfortable and Staff was great."
United States
Kristy
The price is ￥11,452
￥13,183 total
includes taxes & fees
Jun 21 - Jun 22
Econo Lodge Mayo Clinic Area
Coffee service

Americas Best Value Inn Zumbrota

Americas Best Value Inn Zumbrota
2.0 star property
Zumbrota
7.4 out of 10, Good, (531 reviews)
"Great staff"
United States
Roberto
The price is ￥11,125
￥11,946 total
includes taxes & fees
Jun 4 - Jun 5
Americas Best Value Inn Zumbrota
2 indoor pools

Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area
2.5 star property
Kutzky Park
8.0 out of 10, Very Good, (1,012 reviews)
"Good place to stay"
United States
Janet
The price is ￥12,040
￥13,861 total
includes taxes & fees
May 28 - May 29
Med City Inn & Suites - Mayo Clinic Area
Pub

TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area
3.0 star property
Kutzky Park
9.6 out of 10, Exceptional, (531 reviews)
"Great place! Clean, spacious rooms and a lovely breakfast."
United States
Todd
The price is ￥21,659
￥24,934 total
includes taxes & fees
Jun 12 - Jun 13
TownePlace Suites by Marriott Rochester Mayo Clinic Area
In-room safe, desk, iron/ironing board, free cribs/infant beds

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
2.0 star property
Rochester
8.0 out of 10, Very Good, (1,001 reviews)
"Clean room, excellent customer service. "
United States
Olubodun
The price is ￥11,100
￥12,780 total
includes taxes & fees
May 31 - Jun 1
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
Suite, 1 King Bed, Non Smoking | Desk, laptop workspace, iron/ironing board, free wired internet

Quality Inn near Medical Center

Quality Inn near Medical Center
2.5 star property
Rochester
7.8 out of 10, Good, (895 reviews)
"Stayed with our softball team and front desk staff was friendly and helpful. "
United States
Crystal
The price is ￥10,017
￥11,531 total
includes taxes & fees
Jun 21 - Jun 22
Quality Inn near Medical Center
Reception

Hampton Inn Rochester-South

Hampton Inn Rochester-South
2.5 star property
Rochester
9.0 out of 10, Wonderful, (1,001 reviews)
"The room was nice and very clean. The breakfast was tasty with plenty of options. The staff was friendly and helpful. "
United States
Lori
The price is ￥16,633
￥19,148 total
includes taxes & fees
Jun 21 - Jun 22
Hampton Inn Rochester-South
Exterior

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 star property
Downtown Rochester
8.8 out of 10, Excellent, (1,006 reviews)
"Great hotel! Easy access to Mayo, Great restaurant!!!"
United States
Jared
The price is ￥17,041
￥19,619 total
includes taxes & fees
Jun 20 - Jun 21
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Indoor pool, open 7:00 AM to 10:00 PM, sun loungers

Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area
3.5 star property
Downtown Rochester
8.0 out of 10, Very Good, (1,569 reviews)
"Staff are very friendly and helpful"
United States
Shelby
The price is ￥22,171
￥25,526 total
includes taxes & fees
Jun 19 - Jun 20
Kahler Inn and Suites - Mayo Clinic Area
Front of property

Aspen Suites

Aspen Suites
3.0 star property
Rochester
9.0 out of 10, Wonderful, (843 reviews)
"Our room was clean, breakfast was delicious and the staff was excellent. "
United States
Jeff
The price is ￥21,030
￥25,419 total
includes taxes & fees
May 28 - May 29
Aspen Suites
View from property

Kahler Grand Hotel

Kahler Grand Hotel
3.0 star property
Downtown Rochester
8.4 out of 10, Very Good, (2,115 reviews)
"Beautiful, well maintained hotel very convenient to Mayo Clinic offices."
United States
Jeffrey
The price is ￥21,357
￥24,587 total
includes taxes & fees
May 31 - Jun 1
Kahler Grand Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Stay near popular Byron attractions

Oxbow Park

4.4/5 (5 reviews)
Explore the great outdoors at Oxbow Park, a lovely green space in Byron. Check out the top-notch restaurants or charming coffeehouses in this walkable area.
See properties

Top Byron Hotel Reviews

Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

4/10 Poor
"Never replaced towels daily. Doesn’t offer toothbrush or toothpaste.Rooms are dingy and old. Breakfast is ok. Pool facilities are ok. Management is nonchalant but one desk attendant was really nice . A young black guy. Would never stay at this hotel again. Only booked because of the shuttle bus to the hospital. Don’t book because if the price . Spend that extra $20 and go somewhere better. Thank me later"
LaTasha 3-night trip
Posted 1 hour ago
Med City Inn & Suites - Mayo Clinic Area

More cheap stays in Byron

Quality Inn near Medical Center

Quality Inn near Medical Center

5708 Bandel Road NW Rochester MN
The price is ￥10,017 per night from Jun 21 to Jun 22
￥10,017
￥11,531 total
Jun 21 - Jun 22
includes taxes & fees
7.8/10 Good! (895 reviews)

Frequently asked questions

Where is the best place to stay in Byron?
Located 9 mi (14.4 km) from the heart of Byron, Kahler Grand Hotel is a top choice for your stay based on our traveler data. Other good choices for your visit to the area are Kahler Inn and Suites - Mayo Clinic Area and Hyatt House Rochester/Mayo Clinic Area. See all available top hotels, or vacation rentals in Byron.
What's the top vacation rental in Byron?
Magical Nest Hideaway: Visitors like this Byron vacation home rental. It is located on a river and offers a patio, air-conditioning, and WiFi to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. See all vacation rentals in Byron.
If I need to cancel my hotel reservation in Byron, will I receive a refund?
Yes! Most hotel room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Byron.
Where can I learn more about changing or cancelling my trip to Byron?
To find more details about updating your trip to Byron or cancelling it, head over to our customer service page.
Where is the best place to stay near Oxbow Park?
Staybridge Suites Rochester - Commerce Dr NW, an IHG Hotel is one of the top choices for your stay based on our traveler data, and this 3-star hotel offers free breakfast and an indoor pool. You'll find it 7 mi (11.3 km) from Oxbow Park. Other good choices around the area include Baymont by Wyndham Kasson Rochester Area and Hampton Inn & Suites Rochester-North.
How is it to stay in Byron?
Visitors can enjoy all that Byron has to offer including the zoo, golf courses, and bars. Tourists can also enjoy the city's parks and art. In Byron, there are 2 hotels and other accommodations to choose from. Find out more about Byron.
What should I see while I'm in Byron?
Favorite places to visit include Oxbow Park, Links of Byron Mini Golf, and Cheery Meadows Center. A couple of additional sights to add to your agenda are High Point Shopping Center and Byron Town Square. Check out what more to see and do in Expedia's Byron guide.
What's the weather like in Byron?
The hottest months are usually July and August with an average temp of 67°F, while the coldest months are January and February with an average of 21°F. The snowiest months in Byron are January, March, April, and February, with each month seeing an average of 8 inches of snowfall.

Explore a world of travel with Expedia