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Sep 8 - Sep 9
Tomorrow
Sep 9 - Sep 10
This weekend
Sep 11 - Sep 13
Next weekend
Sep 18 - Sep 20

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Our top choices for Wykoff hotels

Deluxe Double Room | Down comforters, pillowtop beds, blackout drapes, soundproofing
Fireplace
Lobby sitting area
Free daily continental breakfast

1. Country Trails Inn & Suites

Country Trails Inn & Suites
Preston
United States
Marsha
￥19,498
￥21,520 total
includes taxes & fees
Sep 9 - Sep 10
Country Trails Inn & Suites
Lobby
Coffee service
Business center
In-room safe, desk, iron/ironing board, rollaway beds (surcharge)

2. Americas Best Value Inn & Suites Spring Valley

Americas Best Value Inn & Suites Spring Valley
Spring Valley
United States
Donna
￥13,719
￥15,143 total
includes taxes & fees
Sep 10 - Sep 11
Americas Best Value Inn & Suites Spring Valley
Front of property
Suite (Buffalo Bill Suite) | Living area | Flat-screen TV
Boat Whirlpool Suite | Desk, iron/ironing board (on request), WiFi (free)
Lobby

3. Stone Mill Hotel & Suites

Stone Mill Hotel & Suites
Lanesboro
United States
Jenifer
￥16,186
￥17,381 total
includes taxes & fees
Sep 16 - Sep 17
Stone Mill Hotel & Suites
Exterior
Front of property
Grand Double Room Single Use, 1 Bedroom, Kitchenette, River View | Soundproofing, iron/ironing board, rollaway beds (surcharge)
Courtyard

4. Green Gables Inn

Green Gables Inn
Lanesboro
United States
MaryPat
￥14,983
￥16,088 total
includes taxes & fees
Oct 4 - Oct 5
Green Gables Inn
Loft | Iron/ironing board, WiFi (free)
Classic Room | Iron/ironing board, WiFi (free)
Lobby
Terrace/patio

5. Country Lodge inn

Country Lodge inn
Harmony
United States
Marti
￥22,560
￥25,896 total
includes taxes & fees
Sep 9 - Sep 10
Country Lodge inn
Reception
Snack bar
Exterior
Lobby

6. Spark by Hilton Rochester South

Spark by Hilton Rochester South
Rochester
United States
Helena
￥13,778
￥15,862 total
includes taxes & fees
Sep 24 - Sep 25
Spark by Hilton Rochester South
Reception
Front of property
Lobby sitting area
Handrails in stairways

7. America's Stay Inn Stewartville

America's Stay Inn Stewartville
Stewartville
United States
Ginger
￥9,018
￥10,145 total
includes taxes & fees
Oct 1 - Oct 2
America's Stay Inn Stewartville
Desk, blackout drapes, iron/ironing board, cribs (free)
Indoor pool, open 7:00 AM to 11:00 PM, sun loungers
Fitness facility
Lobby

8. Comfort Inn & Suites Rochester South Mayo Clinic

Comfort Inn & Suites Rochester South Mayo Clinic
Rochester
United States
Richard
￥13,232
￥15,235 total
includes taxes & fees
Oct 8 - Oct 9
Comfort Inn & Suites Rochester South Mayo Clinic
Front of property
Lobby sitting area
Restaurant
Lobby

9. La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Rochester
United States
Jason
￥11,661
￥13,424 total
includes taxes & fees
Sep 27 - Sep 28
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Desk, laptop workspace, soundproofing, iron/ironing board
Free daily continental breakfast
Lobby sitting area
Lobby

10. MainStay Suites Rochester South Mayo Clinic

MainStay Suites Rochester South Mayo Clinic
Rochester
United States
Linda
￥9,372
￥10,790 total
includes taxes & fees
Sep 27 - Sep 28
MainStay Suites Rochester South Mayo Clinic
Serves lunch, dinner, and happy hour
Indoor pool
Apartment, 1 Bedroom, 2 Queen Beds, Non Smoking | Premium bedding, down comforters, pillowtop beds, desk
Lunch and dinner served

11. AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic
Rochester
United States
Cathy
￥12,387
￥14,261 total
includes taxes & fees
Sep 27 - Sep 28
AmericInn by Wyndham Rochester Near Mayo Clinic
Exterior
Restaurant
Exterior
Suite, 1 King Bed, Jetted Tub | In-room safe, desk, laptop workspace, iron/ironing board

12. Holiday Inn Express Rochester South - Mayo Area by IHG

Holiday Inn Express Rochester South - Mayo Area by IHG
Rochester
United States
Dezel
￥15,415
￥17,747 total
includes taxes & fees
Oct 1 - Oct 2
Holiday Inn Express Rochester South - Mayo Area by IHG
Reception
Restaurant
Indoor pool
In-room safe, laptop workspace, blackout drapes, iron/ironing board

13. Hampton Inn Rochester-South

Hampton Inn Rochester-South
Rochester
United States
Lynne
￥14,536
￥16,733 total
includes taxes & fees
Oct 1 - Oct 2
Hampton Inn Rochester-South
Indoor pool, open 9:00 AM to 10:00 PM, pool umbrellas, sun loungers
Free daily full breakfast
Standard Room, 2 Queen Beds, Accessible, Refrigerator & Microwave | Blackout drapes, soundproofing, iron/ironing board
Executive Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave (Living Room) | Blackout drapes, soundproofing, iron/ironing board

14. Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Rochester
United States
Margita
￥14,696
￥16,919 total
includes taxes & fees
Sep 18 - Sep 19
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Free daily full breakfast
Lobby sitting area
Standard Room, 1 King Bed, Non Smoking | Desk, WiFi (free), bed sheets
Laundry room

15. Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
Rochester
United States
James
￥10,811
￥12,447 total
includes taxes & fees
Oct 4 - Oct 5
Econo Lodge Mayo Clinic Area
2 indoor pools
Desk, laptop workspace, iron/ironing board, WiFi (free)
Lobby sitting area
Fitness facility

16. Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area
Kutzky Park
United States
Hailey
￥9,711
￥11,180 total
includes taxes & fees
Sep 9 - Sep 10
Med City Inn & Suites - Mayo Clinic Area
View from property
Lobby
Exterior
Free daily continental breakfast

17. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
Kutzky Park
United States
Jon
￥17,203
￥19,806 total
includes taxes & fees
Sep 25 - Sep 26
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
Lunch and dinner served
Reception
Hallway
Terrace/patio

18. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Historic Southwest
United States
Carrie
￥16,626
￥19,139 total
includes taxes & fees
Sep 11 - Sep 12
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Terrace/patio
Indoor pool
Egyptian cotton sheets, premium bedding, pillowtop beds, in-room safe
Free daily buffet breakfast

19. Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area
Rochester
United States
Vickie
￥18,834
￥21,682 total
includes taxes & fees
Sep 25 - Sep 26
Home2 Suites by Hilton Rochester Mayo Clinic Area
Lobby
Laundry room
Exterior
Room, 2 Queen Beds, Non Smoking (Ground Floor) | Laptop workspace, iron/ironing board, WiFi (free)

20. Super 8 by Wyndham Rochester Mayo Clinic Area

Super 8 by Wyndham Rochester Mayo Clinic Area
Rochester
United States
Amber
￥8,386
￥9,653 total
includes taxes & fees
Sep 27 - Sep 28
Super 8 by Wyndham Rochester Mayo Clinic Area
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Stay near popular Wykoff attractions

Ed's Museum

You can spend time exploring the galleries in Ed's Museum during your travels in Wykoff. Discover the countryside while you're in the area.
See properties

Top Wykoff Hotel Reviews

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

10/10 Excellent
"The hotel and staff were great. The pool area is one of the best I've seen. It even has a small pool for the kids. The hot tub was great and he pool was warm which made it more enjoyable. Twigs restaurant on site was phenomenal. If you love ribs you have to get them. I will definitely be going back."
Shane 2-night trip
Posted 14 hours ago
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

8/10 Good
"Good"
Quynh 3-night trip
Posted 18 hours ago
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
Comfort Inn & Suites Rochester South Mayo Clinic

Comfort Inn & Suites Rochester South Mayo Clinic

8/10 Good
"They didn’t give us clean towels or take our garbage the 2 days we stayed"
Dennis 2-night trip
Posted 18 hours ago
Comfort Inn & Suites Rochester South Mayo Clinic
EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

10/10 Excellent
"Wish breakfast was included in the room price but great hotel and not too far from Mayo Clinic they do have a shuttle service"
Ashley 1-night trip
Posted 1 day ago
EVEN Hotel Rochester - Mayo Clinic Area by IHG
Hampton Inn Rochester-South

Hampton Inn Rochester-South

10/10 Excellent
"Would recommend!!!"
Amy 2-night trip
Posted 2 days ago
Hampton Inn Rochester-South
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

10/10 Excellent
"Everything was exceptional"
James 2-night trip
Posted 2 days ago
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Aspen Select

Aspen Select

10/10 Excellent
"The room had everything we needed.Restaurant right next Door.We would return."
Claudia 2-night trip
Posted 3 days ago
Aspen Select
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

8/10 Good
"Everything"
jaime 1-night trip
Posted 3 days ago
Med City Inn & Suites - Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

8/10 Good
"Great location, 5 minute walk to Mayo. Great pillows, cold AC! Both very important to us. 4th floor patio is awesome. Staff is very friendly and helpful! Breakfast was also very good. Forgot to mention, with all of the construction around Mayo, this place was super easy to get in and out of."
Mike 1-night trip
Posted 5 days ago
Hyatt House Rochester/Mayo Clinic Area

More cheap stays in Wykoff

Birch Hill Suite Rochester – Med City

Birch Hill Suite Rochester – Med City

3595 Commercial Drive SW Rochester MN
￥8,947
￥10,300 total
Oct 4 - Oct 5
includes taxes & fees
Birch Hill Suite Rochester – Med City
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

435 16th Ave Nw Rochester MN
￥9,711
￥11,180 total
Sep 9 - Sep 10
includes taxes & fees
Med City Inn & Suites - Mayo Clinic Area
Comfort Inn & Suites Rochester South Mayo Clinic

Comfort Inn & Suites Rochester South Mayo Clinic

7320 Airport View Dr Sw Rochester MN
￥13,232
￥15,235 total
Oct 8 - Oct 9
includes taxes & fees
8.8/10 Excellent! (1,009 reviews)
Comfort Inn & Suites Rochester South Mayo Clinic
Brentwood Inn & Suites

Brentwood Inn & Suites

123 Fourth Ave. NW Rochester MN
￥14,452
￥16,638 total
Sep 10 - Sep 11
includes taxes & fees
Brentwood Inn & Suites
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

1517 16th St Sw Rochester MN
￥14,696
￥16,919 total
Sep 18 - Sep 19
includes taxes & fees
8.2/10 Very Good! (1,012 reviews)
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Holiday Inn Express Rochester South - Mayo Area by IHG

Holiday Inn Express Rochester South - Mayo Area by IHG

4141 Maine Avenue SE Rochester MN
￥15,415
￥17,747 total
Oct 1 - Oct 2
includes taxes & fees
Holiday Inn Express Rochester South - Mayo Area by IHG

Frequently asked questions

Where is the best place to stay in Wykoff?
Located 24 mi (38.5 km) from the heart of Wykoff, Kahler Grand Hotel is a top choice for your stay based on our traveler data. Other good choices for your stay in the area are Kahler Inn and Suites - Mayo Clinic Area and Med City Inn & Suites - Mayo Clinic Area. See all available top hotels, or vacation rentals in Wykoff.
What's the top vacation rental that Wykoff has to offer?
Wykoff Historical Jail Haus with Original Jail Cell Bunks.: This Wykoff vacation home rental is equipped with a garden, air-conditioning, and a Smart TV to help you feel comfortable during your stay. See all vacation rentals in Wykoff.
If I need to cancel my hotel reservation in Wykoff, will I receive a refund?
Yes, most hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Wykoff.
Where can I learn more about changing or cancelling my trip to Wykoff?
For more details about changing or cancelling your trip to Wykoff, click here.
What's the best hotel to stay with easy access to Ed's Museum?
Quiet, comfortable bed & breakfast in a gorgeous rural setting! is one of the top choices for your stay based on our traveler data, and this B&B offers free breakfast and private decks. You'll find it 5.5 mi (8.9 km) from Ed's Museum. Other good options around the area include Americas Best Value Inn & Suites Spring Valley and Oakenwald Terrace.
What is the best accommodation for staying close to Rochester International Airport (RST)?
AmericInn by Wyndham Rochester Airport is a popular hotel, featuring free breakfast and an indoor pool. It's located a short 0.6 mi (1 km) from Rochester Intl. Airport. Other choices near the airport include La Quinta Inn & Suites by Wyndham Rochester and Comfort Suites.
How is it staying in Wykoff?
Visitors can enjoy all that Wykoff has to offer including its museums. There are 320 hotels and other accommodations in the surrounding area. Find out more about Wykoff.
What are the top places to visit in Wykoff?
A favorite place to visit is Ed's Museum. You'll also find Forestville Mystery Cave State Park and Four Daughters Vineyard & Winery in the area. Check out what more to see and do in Expedia's Wykoff guide.
What's the weather like in Wykoff?
The hottest months are usually July and August with an average temp of 68°F, while the coldest months are January and February with an average of 22°F. The snowiest months in Wykoff are January, March, February, and April, with each month seeing an average of 8 inches of snowfall.

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