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Find Boutique Hotels in Upstate South Carolina, SC

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Check availability on Upstate South Carolina Boutique Hotels

Our top choices for Upstate South Carolina boutique hotels

Bar (on property)
Hotel Domestique

Hotel Domestique

Hotel Domestique
4.0 star property
Travelers Rest
9.6 out of 10, Exceptional, (30)
"Overall it was an exceptional experience and would highly recommend to anyone looking for a quiet get away."
United States
Chuck
The price is ￥42,829
￥47,112 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Hotel Domestique
Porch
Lake Rabun Hotel & Restaurant

Lake Rabun Hotel & Restaurant

Lake Rabun Hotel & Restaurant
4.0 star property
Lakemont
8.6 out of 10, Excellent, (642)
"This was a perfect get-away spot and we thoroughly enjoyed our time here!"
United States
Meredith
The price is ￥17,045
￥20,381 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Lake Rabun Hotel & Restaurant
Porch
Outpost Inn

Outpost Inn

Outpost Inn
3.0 star property
Highlands
8.6 out of 10, Excellent, (294)
"Very clean room, excellent staff."
United States
Pamela
The price is ￥28,168
￥33,351 total
includes taxes & fees
Dec 16 - Dec 17
Outpost Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Upstate South Carolina Hotel Reviews

Hyatt Place Greenville/Haywood

Hyatt Place Greenville/Haywood

10/10 Excellent
"The room was very nice. Very spacious. The staff was very friendly. The location was great too. "
April 1-night trip
Posted 3 days ago
Hyatt Place Greenville/Haywood

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