A beach with a pier extending into the ocean, a person standing on the shore, and the sun setting over the water.

South San Diego Vacation Rentals

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Our top choices for South San Diego vacation rentals

1. Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
Downtown San Diego
9.4 out of 10, Exceptional, (1,260 reviews)
"Amazing stay! Would definitely come back!"
United States
Dirosia
The price is ¥22,679
¥26,295 total
includes taxes & fees
Nov 19 - Nov 20
Marriott Vacation Club®, San Diego

2. Coronado Beach Resort

Coronado Beach Resort
3.0 star property
Historic Downtown Coronado
9.2 out of 10, Wonderful, (840 reviews)
"Amazing location, amenities, staff"
United States
Javier
The price is ¥25,922
¥28,515 total
includes taxes & fees
Nov 29 - Nov 30
Coronado Beach Resort

3. City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.6 out of 10, Exceptional, (241 reviews)
"Location is great because it is so close to the airport and you won’t even be able to hear the planes. The room is so roomy and has every utility you need !"
United States
Stephanie
The price is ¥18,413
¥26,145 total
includes taxes & fees
Dec 2 - Dec 3
City24 Hotel Little Italy Mission Hills

4. Little Italy Inn - Limited Service Apart Hotel

Little Italy Inn - Limited Service Apart Hotel
2.5 star property
Downtown San Diego
8.4 out of 10, Very good, (406 reviews)
"Great stay nice staff"
United States
Olivia
The price is ¥15,482
¥17,920 total
includes taxes & fees
Nov 9 - Nov 10
Little Italy Inn - Limited Service Apart Hotel

5. Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Uptown Inn by Vantaggio - Limited Service Apart-Hotel
2.5 star property
Hillcrest
8.4 out of 10, Very good, (512 reviews)
"Front desk service was amazing and love the central location to all the LGBTQ bars and restaurants."
United States
Victor
The price is ¥14,806
¥16,694 total
includes taxes & fees
Nov 9 - Nov 10
Uptown Inn by Vantaggio - Limited Service Apart-Hotel

6. Kasa Little Italy San Diego

Kasa Little Italy San Diego
4.5 star property
Downtown San Diego
9.6 out of 10, Exceptional, (561 reviews)
"Super nice amenities - would stay again. Great location"
United States
Nirmeen
The price is ¥32,128
¥48,735 total
includes taxes & fees
Nov 8 - Nov 9
Kasa Little Italy San Diego

7. Stroll to Shore + Mission Blvd: Dog-friendly Home

Stroll to Shore + Mission Blvd: Dog-friendly Home
3.0 star property
Mission Beach
The price is ¥35,278
¥94,082 total
includes taxes & fees
Nov 8 - Nov 9
Stroll to Shore + Mission Blvd: Dog-friendly Home

8. 2 Bedroom Townhome 2 Mins. to the Beach

2 Bedroom Townhome 2 Mins. to the Beach
3.5 star property
Mission Beach
5.8 out of 10, (7 reviews)
"The owner of property cancelled my stay and I can not get anyone to give me a refund. I would appreciate someone getting back to me for this. I will not let it go unsettled. "
United States
Randy
The price is ¥34,837
¥125,085 total
includes taxes & fees
Nov 24 - Nov 25
2 Bedroom Townhome 2 Mins. to the Beach

9. Large Group Wellness Retreat w Spa & Gym

Large Group Wellness Retreat w Spa & Gym
3.0 star property
University City
The price is ¥132,064
¥237,994 total
includes taxes & fees
Nov 13 - Nov 14
Large Group Wellness Retreat w Spa & Gym

10. Kasa Gaslamp Quarter San Diego

Kasa Gaslamp Quarter San Diego
3.5 star property
Downtown San Diego
7.8 out of 10, Good, (240 reviews)
"Wonderful place!"
Canada
Eric
The price is ¥16,568
¥18,878 total
includes taxes & fees
Dec 7 - Dec 8
Kasa Gaslamp Quarter San Diego

11. < 2 Mi to Pacific Beach! Sunny San Diego Escape

< 2 Mi to Pacific Beach! Sunny San Diego Escape
3.0 star property
Pacific Beach
7.4 out of 10, Good, (3 reviews)
"Strategic location for beach, amusement parks and restaurants. Close to major freeways and airport. House has plenty of room across the three floors. Kids loved seeing the seaworld fireworks from the open air rooftop patio. This property has it all. Owner quickly addressed any of our questions and needs. "
United States
Thomas
The price is ¥50,712
¥116,914 total
includes taxes & fees
Nov 15 - Nov 16
< 2 Mi to Pacific Beach! Sunny San Diego Escape

12. Rooftop w/ Views: Modern Little Italy Townhome

Rooftop w/ Views: Modern Little Italy Townhome
3.5 star property
Downtown San Diego
10.0 out of 10, Exceptional, (1 review)
The price is ¥44,570
¥103,293 total
includes taxes & fees
Nov 22 - Nov 23
Rooftop w/ Views: Modern Little Italy Townhome
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top South San Diego Hotel Reviews

Find out more about South San Diego

Search for holiday rentals in South San Diego on Expedia! You can easily find your home rentals, villas, holiday apartments in South San Diego using one of the methods below:

  • View our selection of featured holiday rentals in South San Diego
  • Use the map to find apartments and other holiday homes in the South San Diego neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in South San Diego while they last

Look no further and take a look at our great range of rental properties in South San Diego!

Explore a world of travel with Expedia