Apart Hotels in South San Diego for Rent

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
Jan 9 - Jan 11
In two months
Feb 20 - Feb 22
In three months
Mar 20 - Mar 22
In four months
Apr 17 - Apr 19

Our top choices for South San Diego aparthotels

Premium bedding, pillowtop beds, desk, laptop workspace
Sentral Gaslamp Quarter

Aparthotel in Downtown San Diego

Sentral Gaslamp Quarter
4.0 star property
9.2 out of 10, Wonderful, (609)
"Everything was splendid. Very friendly staff as well. "
United States
Irving
The price is ￥17,121
￥24,375 total
includes taxes & fees
Jan 14 - Jan 15, 2026
Sentral Gaslamp Quarter
Exterior
City24 Hotel Little Italy Mission Hills

Aparthotel in Middletown

City24 Hotel Little Italy Mission Hills
4.5 star property
9.6 out of 10, Exceptional, (108)
"would definitely go back and stay there again "
United States
Kounwick
City24 Hotel Little Italy Mission Hills
Lobby sitting area
Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Aparthotel in Hillcrest

Uptown Inn by Vantaggio - Limited Service Apart-Hotel
2.5 star property
8.4 out of 10, Very Good, (264)
"Overall good place."
United States
Isaac
The price is ￥15,178
￥17,113 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Uptown Inn by Vantaggio - Limited Service Apart-Hotel
Outdoor pool
Kasa Little Italy San Diego

Aparthotel in Downtown San Diego

Kasa Little Italy San Diego
4.5 star property
9.6 out of 10, Exceptional, (356)
"Clean room, Kitchen was fully equipped. Had a great stay!"
United States
Miranda
The price is ￥30,223
￥48,174 total
includes taxes & fees
Dec 30 - Dec 31
Kasa Little Italy San Diego
Deluxe Studio, 1 Queen Bed (Self Check-in with Virtual Front Desk) | Individually decorated, individually furnished, laptop workspace
Kasa Gaslamp Quarter San Diego

Aparthotel in Downtown San Diego

Kasa Gaslamp Quarter San Diego
3.5 star property
8.0 out of 10, Very Good, (154)
"Everything was perfect about the room and location. The minor flaw was the stench in the lobby from the downstairs restaurant and bar. I loved staying here. "
United States
Chris
Kasa Gaslamp Quarter San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top South San Diego Hotel Reviews

Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

10/10 Excellent
"The room was very clean and comfortable and the staff were friendly and helpful. A great value! "
Brandi 5-night trip
Posted 19 hours ago
Days Inn by Wyndham San Diego Hotel Circle

Find out more about South San Diego

South San Diego Aparthotels information

Number of reviews
1,488
Accommodation
10 Aparthotels
Lowest Price
￥17,113
Highest Price
￥48,174

Explore a world of travel with Expedia